So wo nipadua reyɛ kɛse na w’anim ayɛ kurukuruwa te sɛ ɔsram a ayɛ ma? Momma yɛnka ‘Cushing’s Syndrome’ ho asɛm!

So woahyɛ no nsow nnansa yi sɛ wo nipadua no nsusuwii asesa kakra, titiriw wɔ wo nipadua atifi ne wo yafunu ho, na w’anim ayɛ kurukuruwa te sɛ ɔsram a ayɛ ma? Ebia wowɔ srade ketewaa bi a ɛrenyin wɔ wo kɔn akyi. Eyinom nyɛ nneɛma a wɔanhyɛ da kɛkɛ. Ebia hormone tebea bi a wɔfrɛ no Cushing’s Syndrome . Mma ɛnhaw wo, eyi yɛ tebea a mpɛn pii no wobetumi asa. Momma yɛnka eyi ho asɛm tiawa, wɔ ɔkwan a obiara betumi ate ase so.

Sɛ yɛbɛka no tiawa a, dɛn ne Cushing Yare no?

Cushing’s Syndrome, anaa hypercortisolism , yɛ tebea bi a ɛba bere a yɛn nipadua no yɛ cortisol hormone pii dodo no. Seesei ebia woresusuw nea cortisol yɛ ho. Cortisol yɛ hormone a ɛho hia yiye a ntini nketenkete abien a ɛwɔ yɛn asaabo atifi, adrenal glands, na ɛyɛ. Ɛyɛ adwuma pii wɔ yɛn nipadua mu.

• Ɛhwɛ mogya mmoroso so .
• Ɛhwɛ asikre dodow a ɛwɔ mogya mu no so .
• Ɛtew ɔfe a ɛwɔ nipadua no mu so.
• Ɛboa ma aduan a yedi no dan ahoɔden.

Fa no sɛ eyi nyinaa si bere a cortisol dodow a ɛfata pɛpɛɛpɛ wɔ hɔ no. Nanso sɛ saa hormone yi dɔɔso dodo a, nipadua no mu nhyehyɛe afoforo dwumadi fi ase yɛ basabasa. Ɛno ne nea yɛfrɛ no Cushing’s Syndrome. Saa tebea yi abu so wɔ mmea mu sen mmarima. Ɛtaa ba nnipa a wɔadi fi mfe 25 kosi 40 so titiriw.

Dɛn ne nneɛma atitiriw a ɛde Cushing Yare no ba?

Ebia nneɛma pii nti na ɛte saa. Momma yɛnhwɛ emu atitiriw no.

1. Nnuru a wɔde di dwuma (nea ɛtaa de ba) .

Nea ɛtaa de tebea yi ba ne nnuru a wɔde di dwuma bere tenten a wɔfrɛ no glucocorticoids . Wɔtaa frɛ eyinom corticosteroids anaasɛ steroids kɛkɛ . Sɛ nhwɛso no, prednisoneWubetumi anom aduru a wɔfrɛ no. Nnuruyɛfo kamfo nnuru yi kyerɛ wɔ tebea horow te sɛ ayamtu, ntini mu yare, lupus, anaa bere a wɔde akwaa foforo ama obi akyi. Eyinom yɛ nnuru a ano yɛ den yiye a ɛhyɛ ɔfe so. Nanso, sɛ wɔde eyinom di dwuma bere tenten a, Cushing’s Syndrome betumi aba sɛ nea efi mu ba. Afei nso, saa tebea yi betumi aba esiane steroid a wɔde gu nipadua no mu bere nyinaa ma nneɛma te sɛ nkwaa mu yaw ne akyi yaw nti. Saa tebea yi ho yɛ na koraa esiane steroid cream a wɔde yɛ honam ani nyarewa nti, nanso ebetumi aba.

2. Akisikuru a ɛba nipadua no mu

Cortisol dodow nso betumi akɔ soro wɔ yɛn nipadua mu. Nea enti a ɛte saa ne akisikuru ahorow a ɛba nipadua no mu.

• Pituitary Tumors: Sɛ akisikuru ketewaa bi ba pituitary gland a ɛwɔ yɛn amemene no ase no mu a, efi ase yɛ hormone bi a wɔfrɛ no ACTH (Adrenocorticotropic hormone) pii . Saa ACTH hormone yi na ɛma adrenal ntini no yɛ cortisol . Enti sɛ ACTH kɔ soro a, cortisol a wɔyɛ nso kɔ soro ara kwa. Yɛsan frɛ tebea yi Cushing Yare .
• Adrenal Tumors: Ɛtɔ mmere bi a, akisikuru betumi aba adrenal gland no ankasa so, na ebetumi ama cortisol a ɛboro so aba tẽẽ.
• Akisikuru a Ɛwɔ Awotwaa no Akyi: Ɛntaa mma koraa sɛ akisikuru betumi aba wɔ baabi a wɔnyɛ ACTH hormone te sɛ ahurututu , dwensɔtwaa , anaa thyroid ntini , na afi ase ayɛ ACTH.

Saa akisikuru yi betumi ayɛ kokoram anaasɛ ɛnyɛ kokoram.

Dɛn ne yare yi ho sɛnkyerɛnne?

Ebia ɛsono sɛnea yare no ho sɛnkyerɛnne wɔ onipa biara mu, nanso sɛnkyerɛnne ahorow bi wɔ hɔ a ɛtaa ba a wotumi hu bere a yare no mu ayɛ den no. Momma yɛnhwɛ eyinom wɔ pon bi so. Nea ɛka ho no, ebia nnipa binom behu sɛ wɔn yafunu, wɔn asen, wɔn nsa, ne wɔn moma so ntrɛwmu a ɛyɛ kɔkɔɔ anaa pink . Bere a nnompe no reyɛ mmerɛw no, ebia wɔn akyi bɛyɛ wɔn yaw anaasɛ wɔn mpampam abubu, ɛnyɛ bere a wɔkotow, ma nneɛma a emu yɛ duru so nko, na mmom bere a wɔresɔre afi akongua so nso. Sɛ mmofra nkumaa nya saa tebea yi a, wɔn nyin bɛyɛ brɛoo paa , na ebia wɔbɛyɛ kɛse mmoroso nso.

Ɔkwan bɛn so na oduruyɛfo no hu yare yi?

Ebia ebegye nsrahwɛ pii ansa na wo duruyɛfo no atumi akyerɛ sɛ woahu yare no. Nea edi kan no, ɔbɛhwehwɛ wo nipadua mu na wabisa wo nsɛm kakraa bi.

• Dɛn ne wo yare no ho sɛnkyerɛnne?
• Bere bɛn na wudii kan huu eyinom?
• Nnuru bɛn na worenom? (Titiriw steroid) .
• So wote nka sɛ nsakrae bi aba w’adwene mu?

Sɛ oduruyɛfo no gyina saa nsɛm yi so a, sɛ wosusuw sɛ ɔwɔ Cushing Syndrome a, ɔbɛkamfo akyerɛ sɛ wɔnyɛ nhwehwɛmu pii.

• Nnɔnhwerew 24 cortisol sɔhwɛ a wɔmfa nsu mu: Ɛsusuw cortisol dodow a ɛwɔ nsu a wɔaboaboa ano wɔ nnɔnhwerew 24 mu.
• Dexamethasone a wɔde siw ano ho sɔhwɛ: Wɔma steroid aduru a wɔmfa nni dwuma pii bɛyɛ 11 p.m., na ade kyee anɔpa no wɔyɛ mogya mu nhwehwɛmu de hwɛ sɛnea nipadua no da so ara yɛ cortisol dodow.
• Cortisol dodow a ɛwɔ nnompe mu anadwo anadwo: Ɛsusuw cortisol dodow a ɛwɔ nnompe nhwɛsode a wɔfa anadwo mu.

Sɛ nhwehwɛmu ahorow yi si so dua sɛ wowɔ Cushing Syndrome a, ade a edi hɔ ne sɛ wubehu nea ɛde ba . Nea ɛbɛyɛ na wayɛ eyi no, oduruyɛfo titiriw bi betumi ayɛ nhwehwɛmu afoforo pii. Sɛ nhwɛso no, mogya mu nhwehwɛmu de hwɛ ACTH hormone dodow, CT anaa MRI scan.

Dɛn ne ayaresa ahorow a wɔde sa eyi?

Ɔkwan a wɔfa so sa yare no gyina nea ɛde wo tebea no reba no so.

• • Sɛ nea ɛde ba ne steroid nnuru a: Wo duruyɛfo befi ase atew wo steroid dodow so nkakrankakra bere a wodi w’ayaresa tebea foforo (e.g. ayamtu, ntini mu yare) so no.

Nea ɛho hia sen biara: Nnyae steroid a wobɛnom mpofirim a wunnya wo duruyɛfo afotu. Saa a wobɛyɛ no betumi de ɔhaw ahorow a emu yɛ den aba.

• Sɛ nea ɛde ba ne akisikuru a: Ebia ɛho behia sɛ wɔyɛ oprehyɛn na wɔayi akisikuru no afi hɔ. Ɛtɔ mmere bi a, wobetumi de mframa a wɔde sa yare ama de aka oprehyɛn ho.
• Ayaresa afoforo: Sɛ oprehyɛn anaa mframa a wɔde sa yare no antumi anyɛ yiye a, wobetumi de nnuru ama de asiw cortisol a ɛba no ano. Nanso, nnuru yi nso betumi anya ɔhaw ahorow, enti ɛsɛ sɛ wɔnom wɔ aduruyɛfo hwɛ ase.

Ɔkwan bɛn so na wɔbɛsakra asetra ne aduan a wodi aka ayaresa ho?

Bere a woreyɛ ayaresa no, nsakrae a wobɛyɛ wɔ w’asetra kwan ne w’aduan mu no betumi aboa kɛse ma woadi yare no ho sɛnkyerɛnne ahorow so.

• Di aduan pa:
• Di nnuan a calcium ne vitamin D pii wom. Saa tebea yi ma nnompe yɛ mmerɛw. Nufusu, yogurt, kyiisi, nhabannuru a ɛyɛ ahabammono, ne mpataa nketewa (a nnompe wom) ye.
• Tow nnuan a sodium ne ngo/srade pii wom ano hye . Eyinom betumi ama mogya mmoroso ne ne mu duru akɔ soro.
• Di ɛyaw so: .Nneɛma te sɛ aguare a ɛyɛ hyew, aduru a wɔde twitwiw nipadua no brɛoo, ne nsu a wɔde yɛ aerobics betumi aboa ma ntini mu yaw so atew.
• Adwene mu akwahosan: Saa tebea yi betumi ama obi ayɛ mmerɛw. Wo ne w’abusuafo ne wo nnamfo nka eyi ho asɛm. Bisa wɔn mmoa. Sɛ ɛho hia a, hwehwɛ mmoa fi ɔfotufo bi hɔ. Wubetumi abisa wo duruyɛfo no akwankyerɛ.

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