So baabi a ɛyɛ nwonwa wɔ wo honam ani? Ebetumi ayɛ DFSP (Dermatofibrosarcoma Protuberans)!

So woahu sɛ wo honam ani abubu ketewaa bi anaasɛ kɔla asakra pɛn? Ɛtɔ da bi a yɛmfa yɛn adwene nsi so pii, ɛnte saa? Nanso ɛtɔ mmere bi mpo a biribi ketewaa bi te sɛ eyi betumi ayɛ biribi a ɛsɛ sɛ ɛhaw yɛn ho. Ɛnnɛ, yɛbɛka honam ani kokoram bi a ɛntaa nsi nanso ɛho hia ho asɛm. Wɔfrɛ no Dermatofibrosarcoma Protuberans , anaa DFSP tiawa.

Dɛn ne DFSP (Dermatofibrosarcoma Protuberans)?

Sɛ yɛbɛka no tiawa a, DFSP yɛ honam ani kokoram a enyin brɛoo, nanso ɛntaa nsi kakra. Efi ase wɔ yɛn honam ani fã a ɛwɔ mfinimfini, dermis . Ebia wobɛte nso sɛ oduruyɛfo bi frɛ no DFSP.

Esiane sɛ eyi yɛ kokoram a enyin nkakrankakra nti, ɛntaa ntrɛw nkɔ nipadua no afã afoforo. Nanso, ɛnyɛ papa sɛ yebebu yɛn ani agu so. Ɛho hia yiye sɛ wubenya ayaresa a ɛfata na woayi saa akisikuru yi afi hɔ. Ɛno ansa na wobetumi asiw kokoram no agyae sanba (ɛsan ba bio) anaasɛ ɛtrɛw kɔ nipadua no afã afoforo (kokoram a ɛtrɛw kɔ mmeae afoforo) ano. Sɛ wɔsa no yare yie a, obi a ɔwɔ DFSP no wɔ hokwan pa ara sɛ ne ho bɛtɔ no.

So DFSP yi yɛ akisikuru kɛkɛ? Anaasɛ ɛyɛ kokoram?

Dabi, DFSP nyɛ akisikuru a ɛnyɛ hu kɛkɛ. Ɛyɛ tebea a ɛyɛ hu . Sɛ yɛbɛka no pɛpɛɛpɛ a, ɛyɛ kokoram bi a ɛwɔ ntini a ɛyɛ mmerɛw mu, ntini a ɛyɛ mmerɛw sarcoma bi . Sarcomas yɛ kokoram a ɛba mmeae te sɛ ntini, srade, ne honam ani. Ɛtɔ da bi a, wobetumi aka nnompe no nso.

So DFSP betumi atrɛw (metastasize) akɔ nipadua no afã afoforo?

DFSP ntaa nyɛ kokoram bi a ɛtrɛw ntɛmntɛm wɔ nipadua no mu nyinaa. Nanso, ɛntaa mma koraa sɛ nnipa 20 biara mu biako a wɔwɔ DFSP betumi anya kokoram no atrɛw akɔ akyiri asen baabi a edii kan fii ase no. Wɔfrɛ eyi kokoram a ɛtrɛw kɔ mmeae afoforo .

Ɛda adi kɛse sɛ eyi bɛtrɛw sɛ wɔannya ayaresa, anaasɛ sɛ kokoram no atrɛw akɔ honam ani tɔnn, akɔ srade ne ntini mu a.

Ade foforo ne sɛ, ɛwom sɛ wonnim nea ɛde ba ankasa de, nanso sɛ DFSP ba bere a wɔyem a, ebetumi ayɛ kɛse.

Afei nso, nnipa kakraa bi a wɔwɔ DFSP betumi anya bi a ɛyɛ basabasa kɛse na ɛtrɛw ntɛmntɛm a wɔfrɛ no fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS) . Sɛ wɔyɛ oprehyɛn yi DFSP-FS akisikuru yi mpo a, ɛda adi sɛ ɛbɛsan aba na ebetumi atrɛw akɔ mmeae afoforo.

Wɔfrɛ tebea yi sɛ DFSP abu so dɛn?

DFSP yɛ kokoram a ɛntaa nsi koraa. Wɔ wiase nyinaa no, ɛka nnipa bɛyɛ baanan pɛ wɔ nnipa ɔpepem biara mu afe biara. DFSP yɛ 1% kosi 6% wɔ ntini a ɛyɛ mmerɛw sarcomas nyinaa mu.

Saa kokoram yi taa ba mpanyimfo a wɔadi fi mfe 20 kosi 50. Nanso, mmofra nkumaa nso betumi anya honam ani kokoram yi. Nkokoaa binom betumi anya DFSP bere a wɔawo wɔn. Nhwehwɛmu ada no adi sɛ abibifo betumi anya bi kakra sen nnipa a wofi mmusuakuw afoforo mu.

Dɛn ne DFSP ahorow titiriw?

Nyarewa ho animdefo, nnuruyɛfo a wɔde afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ nipadua mu ntini mu no betumi akyerɛ wo DFSP ko a wowɔ no pɛpɛɛpɛ denam nkwammoaa no mu nhwehwɛmu so. Ahorow atitiriw pii wɔ hɔ:

• Bednar tumors (a wɔsan frɛ no pigmented DFSP): Nkwammoaa ahorow yi wɔ melanin , aduru a ɛma honam ani kɔla no pii. Eyi nti na saa akisikuru yi tumi pue kɔla ahorow, a kɔkɔɔ, bruu, bruu, ne kɔkɔɔ ka ho. Saa ɔkwan yi na ɛyɛ bɛyɛ 5% wɔ DFSP a wɔhwehwɛ mu.
• Nkwammoaa akɛse fibroblastoma: Nkwammoaa akɛse a ɛwɔ hɔ na ɛda adi wɔ saa ɔkwan yi so. Wɔsan frɛ saa su yi sɛ mmofra DFSP efisɛ ɛtaa ba mmofra ne mpanyimfo nkumaa mu.
• Fibrosarcomatous dermatofibrosarcoma protuberans (DFSP-FS): Sɛnea yɛadi kan aka no, eyi yɛ ntini a ɛyɛ mmerɛw sarcoma a ɛyɛ basabasa kakra, na ɛtrɛw ntɛmntɛm.
• Myxoid DFSPs: Eyinom yɛ ntini bi a ɛka bom a ɛnyɛ ne kwan so a wɔfrɛ no myxoid stroma. Saa DFSP yi ho yɛ na koraa.

Dɛn na ɛde DFSP ba?

Nea ɛyɛ nwonwa no, nnipa 10 biara a wonya DFSP no mu 9 wɔ awosu mu nsakrae a ɛde tebea no ba . Saa awosu mu nkwaadɔm mu nsakrae yi ba yɛn nkwammoaa mu bere a wɔawo yɛn akyi. Eyi kyerɛ sɛ ɛnyɛ awosu mu sintɔ bi a yenya fii yɛn awofo hɔ na ɛde DFSP ba.

Dɛn ne asiane ahorow a ɛwɔ DFSP a wobenya mu?

Wɔ mmirikatu akyi no, sɛ obi nya honam ani opira anaa akuru biara a, ebetumi ama asiane a ɛwɔ hɔ sɛ obenya DFSP no ayɛ kɛse. Akwan pii wɔ hɔ a honam ani betumi afa so apira:

• Ɔhyew a ɛyɛ hyew
• Wɔreyɛ wɔn radiation therapy
• Oprehyɛn mu ntwitwiridii
• Tattoo ahorow a wɔde yɛ nneɛma

Fa no sɛ, woahyehye kɛse na woabɔ akuru kɛse pɛn. Anaasɛ, woanya mframa a wɔde sa yare foforo bi. Sɛ nneɛma a ɛte sɛɛ sɛe honam ani a, hokwan ketewaa bi wɔ hɔ sɛ tebea te sɛ DFSP bɛba daakye, ɛwom sɛ ɛntaa mma de. Ɛno nti na ɛsɛ sɛ yɛhwɛ nsakrae a ɛba honam ani bere nyinaa.

Dɛn ne DFSP ho sɛnkyerɛnne ahorow?

DFSP ho sɛnkyerɛnne a edi kan no yɛ anifere araa ma ebia yɛrenhu anaasɛ yɛrenhu mpo. Saa akisikuru yi taa ba koko, akyi, mmati, yafunu, anaa akyi. Wobetumi nso anyin wɔ abasa, nan, ti nhwi, ne ano mu.

Mfiase no, ebia wubehu baabi ketewaa bi a ɛte sɛ akuru wɔ honam ani.Ɛyɛ petee na ɛnyɛ yaw. Ebia ɛbɛyɛ te sɛ nea ɛyɛ den kakra sɛ woka a, na kɔla no betumi asesa kakra.

Wɔ nkokoaa ne mmofra nkumaa mu no, DFSP betumi ayɛ te sɛ awo agyiraehyɛde . Saa nsensanee yi taa trɛw bɛyɛ nsateakwaa fã kosi nsateakwaa abien (sentimita 1 kosi 5).

DFSP ho sɛnkyerɛnne ahorow no da adi bere a kokoram no nyin no. Bere a akisikuru no nyin no, ɛpia kɔ honam ani fã a ɛwɔ soro (epidermis) no mu. Eyi ma akuru a ɛyɛ den (nodules) pue wɔ honam ani . Asɛmfua "protuberance" kyerɛ sɛ "ɛpue."

Ebia wubehu saa sɛnkyerɛnne ahorow yi wɔ saa akuru yi mu:

• Ebetumi apaapae anaasɛ mogya atu ntɛmntɛm.
• Ɛbata honam ani denneennen (wontumi mfa nkɔ baabiara).
• Bere a worenyin no, wo honam ani trɛw.
• Ɛyɛ den sɛ wobɛka, anaasɛ ɛte sɛ rɔba.
• Kɔla no betumi ayɛ kɔkɔɔ-biribiri, kɔkɔɔ, bruu, anaa kɔkɔɔ.
• Ebia ɛbɛyɛ mmerɛw kakra bere a wɔde wɔn nsa ka no.

So tebea afoforo wɔ hɔ a ɛde sɛnkyerɛnne ahorow a ɛte sɛ DFSP ba?

Yiw, honam ani yare bi a ɛnyɛ kokoram wɔ hɔ a wɔfrɛ no cellular dermatofibroma . Eyi betumi ayɛ te sɛ DFSP yiye, titiriw wɔ ne mfiase. Nkwammoaa mu dermatofibromas yɛ ntini a ɛyɛ mmerɛw a ɛnyɛ hu. Wɔtaa ba nan no so kɛse. Ɛtɔ mmere bi a, wobetumi ayɛ wɔn yaw na wɔayɛ wɔn yaw. Dermatofibromas dodow no ara nhia ayaresa. Nanso, nyansa wom sɛ woremfa abien no nfrafra, enti sɛ wuhu biribi foforo wɔ wo honam ani a, nyansa wom sɛ wobɛkɔ oduruyɛfo nkyɛn.

Ɔkwan bɛn so na wohu DFSP (Dermatofibrosarcoma Protuberans)?

DFSP yɛ nea honam ani yare ho animdefo , a wɔyɛ nnuruyɛfo a wɔanya ntetee titiriw wɔ honam ani kokoram ne honam ani nyarewa ho na wohu. Wo duruyɛfo bedi kan afa honam ani akisikuru anaa nsensanee no ketewaa bi na ɔde akɔma nhwehwɛmubea ma wɔayɛ ho nhwehwɛmu (wɔyɛ honam ani nipadua mu nhwehwɛmu) . Wobetumi ayi akuru no nyinaa na wɔde akɔma afiri a wɔde yɛ nhwehwɛmu. Afei nyarewa ho animdefo de afiri a wɔde hwɛ nneɛma nketenkete bɛhwɛ ntini no mu ahwɛ sɛ kokoram nkwammoaa wɔ mu anaa.

Sɛ honam ani nhwehwɛmu no si so dua sɛ wowɔ DFSP a, afei wobetumi aka akyerɛ wo sɛ wɔnyɛ MRI scan . Eyi bɛboa ma wɔahu akisikuru no kɛse pɔtee ne sɛnea atrɛw akɔ honam ani. Saa nsɛm yi ho hia yiye ma ayaresa ho nhyehyɛe.

Dɛn ne ayaresa ahorow a wɔde sa DFSP (Dermatofibrosarcoma Protuberans)?

The main and best treatment for DFSP is to remove the tumor surgically. Mpɛn pii no, honam ani yare ho animdefo de ɔkwan titiriw bi a wɔfrɛ no Mohs oprehyɛn di dwuma de yi DFSP akisikuru no fi hɔ. Nea ɛkɔ so wɔ oprehyɛn yi mu ni:

• Nea edi kan no, wɔde aduru bi a ɛma obi dwensɔ gu baabi a wɔsa yare no, enti worente ɛyaw biara.
• Afei, oduruyɛfo no twa kokoram akisikuru no na oyi fi hɔ. Nanso ɛnyɛ akisikuru no nko, na mmom honam ani fã ketewaa bi a ɛwɔ apɔwmuden a atwa ho ahyia nso. Wɔfrɛ eyi sɛ margin .
• Afei, wɔde afiri a wɔde hwɛ nneɛma nketenkete hwehwɛ ntini a wɔayi afi mu no anoano (ahye) mu hwɛ sɛ kokoram nkwammoaa bi da so ara wɔ hɔ anaa.
• Sɛ kokoram nkwammoaa da so ara wɔ anoano a, oduruyɛfo no beyi ntini foforo bi afi baabi a wɔyɛɛ oprehyɛn no bio no.
• Wɔ saa kwan yi so no, wɔkɔ so yi ntini ahorow no kosi sɛ wonhu kokoram nkwammoaa biara wɔ nkyɛnkyɛn.
• , ‍ (reconstructive surgery) .

So ayaresa afoforo wɔ hɔ a wɔde sa DFSP a wɔnyɛ oprehyɛn?

Sɛ wɔyɛ oprehyɛn yi DFSP akisikuru no mpo a, ɛtɔ mmere bi a ebetumi asan aba. Wɔ typical wide excision akyi no, 20% kosi 30% hokwan wɔ hɔ sɛ wɔbɛsan aba wɔ mfe abiɛsa ntam. Mohs oprehyɛn akyi no, asiane yi so tew kɔ 4% kosi 5%. Nanso, ɛho hia sɛ yɛma yɛn ani da hɔ, efisɛ akisikuru betumi asan aba bio wɔ mfe 10 anaa nea ɛboro saa akyi mpo.

Ɛtɔ mmere bi a, sɛ kokoram no atrɛw akɔ nipadua no afã afoforo (metastatic DFSP), anaasɛ sɛ akisikuru no sõ dodo anaasɛ ɛwɔ baabiara dodo sɛ wobetumi ayɛ oprehyɛn ayi afi hɔ a, nnuruyɛfo de aduru bi a wɔfrɛ no Imatinib di dwuma. Saa aduru yi nso tumi ma akisikuru no so tew, na ɛma ɛyɛ mmerɛw sɛ wobeyi afi hɔ wɔ oprehyɛn mu.

Afei nso, sɛ oprehyɛn ntumi nyi kokoram no mfi hɔ koraa, anaasɛ oprehyɛn no ntumi nyɛ yiye koraa a, wobetumi de mframa a wɔde sa yare adi dwuma.

Dɛn ne obi a ɔwɔ DFSP no anidasoɔ?

Eyi yɛ asɛm a ɛma awerɛkyekye ankasa. Since DFSP is a slow-growing, indolent cancer, with proper treatment, more than 99% of people will survive for 10 years or more. Enti, ade a ɛho hia sen biara ne sɛ woremmɔ hu na wudi wo duruyɛfo afotu akyi.

Dɛn na metumi ayɛ na ama m’adwene atu mpɔn?

Nneɛma pii wɔ hɔ a wubetumi ayɛ na ama w’adwene atu mpɔn:

• Yɛ honam ani nhwehwɛmu daa. Hwehwɛ nsakrae foforo biara, nsensanee, anaa akuru biara a ɛwɔ wo honam ani. Sɛ wuhu biribi a, ka kyerɛ wo duruyɛfo ntɛm ara.
• Sɛ wosa yare wie a, anyɛ yiye koraa no, kɔ wo duruyɛfo nkyɛn kɔhwɛ wo honam ani asram abiɛsa kosi asia biara wɔ mfe abiɛsa a edi kan no mu. Afei kɔ kɔhwɛ pɛnkoro afe biara, anaa sɛnea wo duruyɛfo kyerɛ no.
• Tew owia a wobɛbɔ no so. UV mframa a efi owia mu no ma asiane a ɛwɔ hɔ sɛ obi benya honam ani kokoram afoforo no yɛ kɛse. Enti, hyɛ aduru a ɛbɔ wo ho ban fi owia ho bere a worekɔ owia mu no, hyɛ ntade a ɛbɔ wo ho ban , na to bere a wode bɛbɔ abɔnten wɔ da no fã a ɛyɛ hyew sen biara no ano hye.

Bere bɛn na ɛsɛ sɛ mekɔ oduruyɛfo nkyɛn?

Sɛ wuhu nsakrae foforo biara wɔ wo honam ani, titiriw sɛ wowɔ nea edidi so yi bi a, hwɛ hu sɛ wobɛkɔ oduruyɛfo nkyɛn:

• Nkuruwankuruwa anaa nsensanee foforo a ɛkɔ so tra hɔ, anaasɛ honam ani nyini foforo.
• Nsakrae a ɛba akisikuru, awo agyiraehyɛde, akuru dedaw, anaa tattoo mu.
• Sɛ akuru a ɛwɔ honam ani no mogya tu ntɛmntɛm a.

Kae sɛ mpɛn pii no, honam ani nsakrae betumi ayɛ nea asiane biara nni ho. Nanso, nsakrae bi betumi ayɛ honam ani kokoram ho sɛnkyerɛnne. Enti, sɛ w’adwene mu yɛ wo naa a, ɛbɛyɛ papa sɛ wobɛkɔ oduruyɛfo nkyɛn akɔsiesie.

Dɛn na ɛsɛ sɛ mibisa me duruyɛfo?

Sɛ wohu sɛ wowɔ DFSP a, ebia wobɛpɛ sɛ wubisa wo duruyɛfo nsɛm te sɛ:

• Dɛn nti na minyaa honam ani kokoram yi?
• So mewɔ asiane mu sɛ menya honam ani kokoram ahorow afoforo?
• Dɛn ne ayaresa a eye sen biara ma me?
• So asiane wɔ hɔ sɛ kokoram yi bɛtrɛw akɔ nipadua no afã afoforo?
• Mpɛn ahe na ɛsɛ sɛ meba ma wɔyɛ kokoram ho nhwehwɛmu?

Sɛ wuhu nsɛmmisa yi ho mmuae a, ɛbɛboa wo ma woate tebea no ase yiye na ebetumi aboa wo ma w’ayaresa ne daakye nhyehyɛe ahorow mu ada hɔ.

Nea etwa to no, nneɛma a ɛsɛ sɛ yɛkae

Ɛwom sɛ DFSP yɛ honam ani kokoram a ɛntaa nsi de, nanso ɛnyɛ den koraa sɛ ɛbɛtrɛw akɔ nipadua no afã afoforo. Nanso, oprehyɛn a wɔde sa yare ho hia na ama nyin no agyae. Sɛ wuhu ntɛm na wosa wo yare yiye a, ebetumi ama w’adwene atu mpɔn kɛse. Enti, hwɛ wo honam ani hwɛbea na sɛ wuhu biribi a ɛyɛ soronko a, kɔ oduruyɛfo nkyɛn. Ɛnyɛ wo nko ara, na nnuruyɛfo bi wɔ hɔ a wobetumi aboa wo wɔ akwantu yi mu.

` DFSP, honam ani kokoram, honam ani kokoram, honam ani akuru, Mohs oprehyɛn, kokoram ho sɛnkyerɛnne, honam ani nyarewa