Momma yensua endothelium - tumi a ahintaw wo wo nipadua mu ho ade.

Yɛn nyinaa nim sɛ mogya sen fa yɛn nipadua nyinaa mu, ɛnte saa? Saa mogya yi nsen fa nsukorade ahorow bi a wɔfrɛ no mogya ntini a ɛte sɛ nsu nhama mu kɛkɛ. Enti so woasusuw sɛnea saa nsukorade yi mu te ho pɛn? Ɛnnɛ yɛbɛka nkwammoaa a ɛyɛ nwonwa a ɛyɛ tratraa paa a ɛyɛ saa nsukorade no mu ho asɛm. Yɛfrɛ eyi ‘endothelium’ . Eyi nyɛ aduru a wɔde kata wo nipadua mu ara kwa, ɛyɛ nkwammoaa nketenkete nhyehyɛe bi a ɛyɛ nnwuma pii a ɛho hia yiye a ɛka wo nipadua nyinaa akwahosan.

Sɛ yɛbɛka no tiawa a, dɛn ne saa endothelium yi?

Fa no sɛ mogya ntini biara a ɛwɔ wo nipadua mu no wɔ ntini a ɛyɛ tratraa paa na ɛyɛ torotoro, a ne kɛse yɛ nkwammoaa biako pɛ, te sɛ ɔfasu ho mfonini. Ɛno ne endothelium no. Ɛyɛ nkwammoaa soronko bi a wɔfrɛ no endothelial cells.

Saa endothelium koro yi ara na ɛwɔ mmeae yi wɔ wo nipadua mu:

• Ntini: Ntini akɛse a ɛde mogya fi koma no mu kɔ nipadua no afã afoforo.
• Ntini: Mogya ntini a ɛde mogya fi nipadua no mu san kɔ koma no mu.
• Capillaries: Mogya ntini nketenkete a ɛyɛ fɛ yiye.
• Lymph capillaries: Ntini a ɛyɛ yɛn ntini nhyehyɛe no dea.

Ɛnyɛ ɔfasu bi kɛkɛ. Ɛyɛ adwuma sɛ beae titiriw a wo mogya ne wo nipadua mu ntini a aka no sesa nsɛm ne aduannuru. Ɛho hia yiye, mprempren nyansahufo bu endothelium sɛ ɛyɛ akwaa akɛse a ɛwɔ yɛn nipadua mu no mu biako . Yiw, ɛyɛ akwaa, te sɛ mmerɛbo ne koma no ara pɛ.

Ɔsom bɛn na endothelium no de ma yɛn nipadua?

Adwuma a nkwammoaa ketewaa yi yɛ no yɛ nwonwa. Ma yɛnhwɛ emu atitiriw no bi.

Ɛhwɛ mogya ntini a ɛtwetwe ne nea ɛtrɛw so

Ɛsɛ sɛ wo mogya ntini trɛw (vasodilate) bere a ɛho hia, na ɛyɛ teateaa (vasoconstrict) bere a ɛho hia. Endothelium no na ɛhwɛ eyi so.

Susuw ho saa kwan yi so.

• Sɛ woteɛteɛ w’apɔw mu a: Wo ntini hia mogya ne mframa pa pii. Endothelium no de nsɛnkyerɛnne kɔma ma ɛtrɛw mogya ntini a ɛwɔ saa beae no mu, na ɛma mogya tu ntɛmntɛm.
• Da a awɔw wom paa: Wopɛ sɛ wokora wo nipadua mu hyew so. Eyi ma mogya ntini a ɛwɔ wo nsa ne wo nan mu no twetwe kakra, na ɛboa ma mogya kɔ wo akwaa atitiriw no mu.

Saa kwan yi so no, ɛboa kɛse wɔ wo mogya mmoroso so na wohwɛ hu sɛ akwaa nyinaa benya mogya dodow a ɛho hia no mu.

Ɔhwɛ nsu dodow a efi mogya no mu kɔ ntini ahorow no mu no so

Endothelium no te sɛ nea wɔde yiyi mu. Ɛma aduannuru ne mframa pa a efi mogya no mu fa mu kɔ ntini ahorow no mu, na ɛsan yɛ adwuma sɛ akwanside a ɛbɔ ho ban a ɛmma nneɛma a epira ne awuduru ntumi nkɔ mogya no mu. Nanso, sɛ wunya ɔyare mmoawa a, ɛsɛ sɛ yɛn nipadua mu nkwammoaa a ɛko tia nyarewa no fi mogya no mu kɔ baabi a ɔyare no wɔ. Afei endothelium no ankasa bue kwan ma saa nkwammoaa no kɔ hɔ.

Ɛmma mogya ntumi nkɔ (Thrombosis) .

Mpɛn pii no, mogya a ɛtwetwe mogya ntini mu no yɛ asiane kɛse, ɛnte saa? Ebetumi de tebea horow a emu yɛ den te sɛ komayare ne akisikuru aba. Endothelium a ɛwɔ apɔwmuden no ma nnuru titiriw te sɛ nitric oxide pue, na ɛma mogya no kɔ so tra hɔ na ɛmma mogya no nkɔ so ntew a ɛho nhia.

Endothelium no kɛse te dɛn? Ɛhe na ɛwɔ yɛn nipadua mu?

Sɛ obi bisa wo baabi a wo koma wɔ a, wode wo nsa kyerɛ wo moma so. Sɛ obi bisa wo baabi a w’amemene wɔ a, ɔde ne nsa kyerɛ wo ti. Nanso sɛ obi bisa wo baabi a endothelium no wɔ a, wubetumi atwe adwene asi wo nipadua no fã biara so. Ɛtrɛw kɛse wɔ nipadua no nyinaa mu.

Susuw ho hwɛ, sɛ wɔkyekyɛɛ mogya ntini a ɛwɔ onipa a wɔkyekyem pɛpɛɛpɛ mu nyinaa fi awiei kosi awiei a, anka ne tenten bɛyɛ kilomita 100,000 ! Ɛno boro nea ɛdɔɔso sɛ wobɛnantew wiase nyinaa mprenu. Na wɔde saa endothelium yi akata ne tenten yi nyinaa so. Sɛ wofa ne mpɔtam a, mpɛn pii no ɛsõ sen tɛnis agodibea ahorow pii. Afei nso, nhyehyɛe yi nyinaa yɛ endothelial nkwammoaa bɛboro ɔpepepem biako (1,000,000,000,000).

Dɛn ne Endothelial Dysfunction?

Eyi ne ɔfã a ɛho hia sen biara a ɛsɛ sɛ yɛn nyinaa yɛ aso. ‘Endothelial Dysfunction’ kyerɛ ara ne sɛ endothelial nkwammoaa no asɛe na wontumi nyɛ wɔn adwuma yiye. Ɛte sɛ nea asphalt a ɛwɔ ɔkwan bi so no afi hɔ, na ɛma ɛyɛ den ma kar ahorow sɛ wɔbɛka.

Dɛn na ɛba bere a endothelium no ankasa yɛ mmerɛw no?

Sɛ endothelium no sɛe a, ne soro a ɛyɛ torotoro no yɛ mmerɛw. Afei srade bɔne (LDL) fi ase boaboa ano wɔ saa mmeae a ɛhɔ yɛ toro no. Wɔ mmuaema mu no, nkwammoaa a efi nipadua no mu tumi a ɛko tia nyarewa no mu ba bɛboaboa ano wɔ hɔ. Eyinom nyinaa boaboa ano, na bere kɔ so no, ɛyɛ ‘srade a ɛwɔ so’ (plaque) .

Bere a srade a ɛwɔ mu yi nyin no, mogya ntini no twetwe fi mu. Afei eyi siw mogya a ɛsen no kwan. Sɛ da bi srade a ɛwɔ mu yi pae a, mogya a ɛbɛtɔ wɔ saa beae no na asiw mogya ntini no ano koraa.

Enti, obi a ne endothelium ayɛ mmerɛw no betumi anya asiane ahorow a edidi so yi:

• Koma mu yare
• Nnwodwoɔ
• Coronary ntini mu yare
• Ntini a ɛwɔ akyi no yare
• Asaabo mu yare
• Insulin a ɛko tia

Enti yɛbɛyɛ dɛn ama saa endothelium yi anya apɔwmuden?

Asɛmpa no ne sɛ yebetumi abɔ saa endothelium a ɛsom bo yi ho ban denam yɛn asetra kwan a yɛbɛsakra no so.

Sɛ yɛbɛka no tiawa a, yɛn nipadua no ma nneɛma bɔne bi a wɔfrɛ no ‘free radicals’ . Eyinom sɛe yɛn endothelial nkwammoaa no. Wɔfrɛ nneɛma pa a ɛboa ma woyi saa nneɛma bɔne yi fi hɔ no ‘antioxidants’ . Enti nea ɛsɛ sɛ yɛyɛ ne sɛ yɛbɛtew free radicals a ɛba no so denam nnuan a nnuru a ekum ɔyare mmoawa pii wom a yebedi so.

Nneɛma pa a ɛsɛ sɛ woyɛ

Di nnuan a nnuru a ekum ɔyare mmoawa pii wom pii.

• Nnuadewa a ɛyɛ ahabammono tuntum: spinach, kale, collard greens.
• Nnuaba ne nhabannuru a ne kɔla yɛ hyew: tomato, karɔt, beets, bell peppers, oranges, grapefruit.
• Aburow a wɔayam: aburow a ɛyɛ bruu, oats, ne atoko.
• Ngo a ahoɔden wom: ngodua ngo, avocado.

Wubetumi ne wo duruyɛfo akasa afa saa aduan yi ho (e.g., Mediterranea aduan) na woayɛ nsakrae a ɛfata wo.

Nneɛma bɔne a ɛsɛ sɛ wɔkwati

Saa nneɛma yi ma free radicals a ɛwɔ wo nipadua mu no yɛ kɛse.

• Sigaretnom: Eyi ne ɔtamfo a odi kan. Gyae nnɛ.
• Nnuan a asikre ne nnɔkɔnnɔkɔwade pii wom: Eyinom ma ɔfe a ɛwɔ nipadua no mu no yɛ kɛse.
• Nnuan a wɔayɛ ho adwuma: Ebia srade ne nnuru a epira wɔ eyinom mu.
• Adwennwen a ɛboro so.
• Da a wontumi nna sɛnea ɛsɛ.

Afei nso, apɔw-mu-teɛteɛ daa ho hia yiye ma endothelial akwahosan. Sɛ woteɛteɛ w’apɔw mu a, nitric oxide a wonya no kɔ soro, na ɛma wo mogya ntini no kɔ so yɛ den. Biribi a ɛyɛ mmerɛw te sɛ nantew simma 30 da biara mpo betumi ama nsakrae kɛse aba.

Sɛ wowɔ ayaresa tebea bi te sɛ mogya mmoroso, asikreyare, anaa srade dedaw a, ɛho hia sɛ wudi wo duruyɛfo ayaresa nhyehyɛe akyi pɛpɛɛpɛ . Nnuru yi botae ne sɛ wobedi tebea horow yi so na ama wo endothelium no asɛe no kakraa bi.