So ɛtɔ mmere bi a wote nka sɛ w’ani fitaa no yɛ kɔkɔɔ kakra? Anaasɛ w'adamfo bi abisa wo pɛn sɛ, "Dɛn nti na m'ani ayɛ kɔkɔɔ?"? Sɛ ɛba saa a, mpofirim ara wote ehu nka sɛ, "Oh, so me nso mewɔ jaundice?" Efisɛ yɛn nyinaa nim sɛ aniwa a ɛyɛ kɔkɔɔ betumi ayɛ ɔhaw bi a ɛwɔ mmerɛbo no ho ho sɛnkyerɛnne. Nanso ɛnyɛ mmerɛbo mu yare a emu yɛ den na ɛde jaundice nyinaa ba. Ɛnnɛ yɛbɛka tebea bi a nnipa pii wɔ ho asɛm, nanso ɛno nyɛ biribi a ɛsɛ sɛ wosuro dodo. Ɛno ne Gilbert Syndrome a ɛyɛ yare no.
Sɛ yɛbɛka no tiawa a, dɛn ne Gilbert Syndrome?
Gilbert Syndrome nyɛ yare a emu yɛ den. Ɛyɛ awosu mu tebea a abu so yiye a efi awo ntoatoaso so kɔ awo ntoatoaso so. Fa no sɛ mogya mu nkwammoaa kɔkɔɔ a ɛwɔ yɛn nipadua mu no wuwu bere a bere kɔ so no. Afei, sɛ wɔsɛe a, wɔyɛ nwura kɔkɔɔ bi a wɔfrɛ no bilirubin . Ɛte sɛ nwura a ɛyɛ ahabammono a ɛreporɔw. Yɛn mmerɛbo no dwumadi titiriw biako ne sɛ ebeyi ade fĩ a wɔfrɛ no bilirubin yi afi nipadua no mu.
Nnipa a wɔwɔ Gilbert Syndrome no wɔ ɔkwan a ɛyɛ brɛoo a wɔfa so yi bilirubin fi hɔ. Nea enti a ɛte saa ne sɛ wɔn mmerɛbo no mu enzyme bi a ɛboa ma wɔyɛ saa no sua. Wɔfrɛ awosu mu abɔde a ɛka eyi no `UGT1A1`. Sɛ wubenya saa tebea yi a, ɛsɛ sɛ wunya awosu mu abɔde a wɔasesa yi abien, biako fi wo maame hɔ na biako fi wo papa hɔ.
Sɛ yɛbɛka no tiawa a, ɛte sɛ adwumayɛbea a ɛwɔ mmerɛbo mu, baabi a bilirubin a wɔde yɛ nneɛma fĩ no reyɛ adwuma brɛoo kakra no. Enti ɛtɔ mmere bi a ade kɔkɔɔ a wɔfrɛ no bilirubin yi boaboa ano wɔ mogya no mu. Ɛno ne bere a aniwa ne honam ani hwɛbea yɛ kɔkɔɔ. Yɛsan frɛ eyi sɛ jaundice . Nanso kae sɛ Gilbert Syndrome nyɛ yare a ɛsɛe mmerɛbo no na ɛnyɛ biribi a ɛsɛ sɛ yesuro.
Dɛn ne sɛnkyerɛnne ahorow no? Dɛn nti na wopue mpofirim?
Mpɛn pii no, nnipa a wɔwɔ Gilbert Syndrome no nkyerɛ yare no ho sɛnkyerɛnne biara. Enzyme no dɔɔso sɛ ɛbɛhwɛ bilirubin dodow a ɛwɔ wɔn nipadua mu no so.
Nanso wɔ nsɛm titiriw bi mu no, bilirubin dodow a ɛwɔ mogya no mu no kɔ soro kakra. Ɛno na aniwa fitaa ne honam ani yɛ kɔkɔɔ. Yɛfrɛ eyi sɛ jaundice. Sɛ wuhu sɛ ɛyɛ kɔkɔɔ a ɛte sɛɛ a, akyinnye biara nni ho sɛ ɛsɛ sɛ wokɔ oduruyɛfo nkyɛn kɔhwehwɛ sɛ ebia biribi foforo bi a emu yɛ den de ba anaa.
Ɛtɔ da bi a, saa kɔkɔɔ yi betumi de tiyɛ, ɔbrɛ, ne yafunu a ɛyɛ mmerɛw aka ho.
Enti dɛn nti na bilirubin dodow yi kɔ soro mpofirim? Ntease pɔtee pii wɔ hɔ a ɛka no. Ma yɛnhwɛ nea wɔyɛ.
| Nneɛma a ɛkanyan obi a ɛma bilirubin dodow kɔ soro | Dɛn na ɛrekɔ so? |
|---|---|
| Ɔbrɛ | Nneɛma te sɛ sɔhwɛ ne adwuma mu haw betumi asakra nipadua no nneyɛe. |
| Nsu a ɛho ntew | Bere a wonnom nsu a ɛdɔɔso. |
| Adidi a wohuruw | Bere a woredi mmuada anaasɛ worehuruw adidi esiane adagyew nti. |
| Nyarewa a wɔde nyarewa ba | Sɛ wunya yare bi te sɛ atiridii anaa atiridiinini a, wo nipadua ko tia. |
| Apɔw-mu-teɛteɛ a emu yɛ den | Bere a wo nipadua abrɛ dodo sɛ ebetumi adi ho dwuma no. |
| Nsaden | Nsã ma mmerɛbo no yɛ den kɛse. |
| Brayɛbea a ɛba mmea mu | Ebia nsakrae a ɛba nipadua mu nkwaadɔm mu na ɛde tebea yi ba. |
Ɔkwan bɛn so na oduruyɛfo hu eyi?
Mpɛn pii no, wohu sɛ obi anya Gilbert Syndrome wɔ akwanhyia mu. Ebia sɛ woreyɛ wo mogya mu nhwehwɛmu ahu tebea foforo bi a, wo duruyɛfo no hu sɛ wo bilirubin dodow boro nea ɛte daa no so kakra. Ɛno ne bere a wosusuw sɛ ɛyɛ saa.
Wɔtaa di anammɔn yi akyi de hu yare no:
- Mogya mu nhwehwɛmu:Wɔhwɛ sɛnea bilirubin dodow te. Wɔyɛ mmerɛbo dwumadi ho nhwehwɛmu nso de hwɛ sɛnea mmerɛbo no yɛ adwuma. Eyi betumi ayi mmerɛbo mu nyarewa afoforo a emu yɛ den afi hɔ.
- Ultrasound Scan: Ɛtɔ mmere bi a wobetumi ayɛ scan de ahwɛ ahu sɛ ɔhaw foforo biara nni mmerɛbo no ho (te sɛ abo anaa srade a ɛwɔ hɔ).
- Gene Tests: Wobetumi ayɛ saa sɔhwɛ yi de asi so dua sɛ ebia mutation bi wɔ `UGT1A1` gene no mu anaa. Nanso, ɛnyɛ bere nyinaa na wɔyɛ eyi.
- Liver Biopsy: Wɔntaa nyɛ eyi mfa nhwɛ sɛ ebia Gilbert Syndrome wɔ hɔ anaa. Sɛ wosusuw sɛ yare foforo a emu yɛ den bi wɔ hɔ nkutoo a, na wɔyɛ.
So aduru bi wɔ hɔ a wɔde sa Gilbert Syndrome? Dɛn na ɛsɛ sɛ yɛyɛ?
Asɛmpa no ni. Gilbert Syndrome nyɛ yare a ɛsɛ sɛ wɔsa. Yellowing (jaundice) a ɛde ba no rempira wo nipadua no bere tenten.
Enti nea ɛsɛ sɛ yɛyɛ ne sɛ yɛbɛtwe yɛn ho afi nneɛma a ɛkanyan adwene a ɛma bilirubin dodow kɔ soro a yɛadi kan aka ho asɛm no ho sɛnea yebetumi.
- Mma nntwa adidi so. Didi wɔ bere ano.
- Nom nsu pii. Ɛho hia paa sɛ anyɛ yiye koraa no wobɛnom nsu lita 2-3 da biara.
- Tew adwennwen so. Ma w’adwene dwo denam adwennwen, nnwom a wubetie, anaa anigyede bi a w’ani gye ho a wode wo ho bɛhyɛ mu no so.
- Da yiye. Anyɛ yiye koraa no, da nnɔnhwerew 7-8 da biara.
- To nsa nom ano hye anaasɛ gyae koraa.
- Kwati apɔw-mu-teɛteɛ a ɛma nipadua no yɛ den dodo. Nneɛma te sɛ nantew a wɔkɔ daa ne yoga ye.
Asɛm a ɛhaw adwene titiriw!
Eyi ne baabi a ɛsɛ sɛ wode w’adwene si so kɛse. Enzyme koro no ara a ɛpaapae bilirubin a ɛwɔ yɛn mmerɛbo mu no nso boa ma yeyi nnuru bi fi nipadua no mu. Esiane sɛ saa enzyme no yɛ adwuma brɛoo kakra wɔ obi a ɔwɔ Gilbert Syndrome mu nti, saa nnuru no tra nipadua no mu kyɛ na ɛda adi sɛ ɛde ɔhaw ahorow bɛba.
Sɛ́ obi a ɔwɔ Gilbert Syndrome no, ɛsɛ sɛ wo ne wo duruyɛfo kasa fa aduru foforo biara a worenom ho.
Sɛ nhwɛso no, nnuru a wɔtaa de di dwuma te sɛ acetaminophen (Panadol, Paracetamol) no hyɛ saa kuw yi mu. Nnuru te sɛ `Irinotecan` a wɔde sa kokoram, ne `Protease inhibitor` a wɔde sa HIV ne Hepatitis C nso ka ho.
Enti, sɛ wokɔ oduruyɛfo nkyɛn a, ɛho hia yiye sɛ woka sɛ, "Mewɔ Gilbert Syndrome." Afei oduruyɛfo no besusuw saa asɛm no ho bere a ɔrekyerɛw wo nnuru no.
Nkrasɛm a Wɔde Kɔ Fie
- Gilbert Syndrome nyɛ yare a ɛsɛ sɛ wosuro. Ɛyɛ awosu mu tebea a asiane biara nni ho a wɔde ma awo ntoatoaso ahorow.
- Nsɛnkyerɛnne titiriw ne aniwa ne honam ani yɛ kɔkɔɔ (jaundice) wɔ bere a adwennwen, yare, anaa mmuadadi mu.
- Saa tebea yi nhia ayaresa. Nea ɛsɛ sɛ woyɛ ne sɛ wobɛkwati nneɛma a ɛkanyan wo a ɛma bilirubin dodow kɔ soro.
- Sɛ w’ani anaa w’ani reyɛ kɔkɔɔ a, hwɛ hu sɛ wobɛhwehwɛ aduruyɛfo afotu na ama woahwɛ ahu sɛ ɛnyɛ tebea foforo a emu yɛ den.
- Sɛ wunim sɛ wowɔ Gilbert Syndrome a, ɛho hia yiye sɛ wobɛbɔ wo duruyɛfo amanneɛ ansa na woanom nnuru foforo biara.
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