So phosphate sua wɔ wo mogya mu? Momma yɛnka saa tebea yi ho asɛm (Hypophosphatemia)!

Ebia woahu biribi a wɔfrɛ no "Phosphate" bere a wohwɛ mogya ho amanneɛbɔ bi no, ɛnte saa? Anaasɛ ebia oduruyɛfo bi aka ho asɛm akyerɛ wo. Saa phosphate yi ho hia yɛn nipadua no yiye ankasa. Enti, sɛ phosphate dodow yi so tew wɔ mogya no mu a, dɛn na ɛba? Ɛno ne nea yɛfrɛ no `(Hypophosphatemia)`. Momma yɛnka eyi ho asɛm nkɔ akyiri, tiawa koraa, nnɛ.

Dɛn na phosphate a ɛba fam kyerɛ? So ɛyɛ `(Hypophosphatemia)`?

Sɛ yɛbɛka no tiawa a, yiw. Hypophosphatemia yɛ tebea a ɛma mineral bi a wɔfrɛ no phosphate dodow a ɛwɔ wo mogya mu no sua. Phosphate yɛ electrolyte a ɛho hia ma yɛn nipadua no dwumadi pii. Ɛyɛ adwuma te sɛ batere wɔ yɛn nipadua mu. Saa tebea yi betumi ayɛ nea emu nyɛ den anaasɛ emu yɛ den. Ebetumi nso aba mpofirim (acute) anaasɛ bere kɔ so (a enni sabea).

Enti, ɔkwan bɛn so na saa phosphate yi ho hia nipadua no?

Susuw sɛnea phosphate yi yɛ wɔ yɛn nipadua mu no ho hwɛ!

• Yɛn nnompe ne yɛn sẽ a yɛbɛkyekyere na yɛama ayɛ den: phosphorus a ɛwɔ yɛn nipadua mu no 85% wɔ yɛn nnompe mu. Enti eyi ho hia ma nnompe a ɛyɛ den.
• Ma ntini ahorow no nyɛ adwuma yiye: Yɛn ntini hia phosphate na ama yɛatumi ayɛ adwuma yiye.
• Ɛboa ma ntini twetwe: Sɛ yɛkeka yɛn nsa ne yɛn nan, na sɛ yɛn koma bɔ a, yɛn ntini twetwe, enti eyi nso boa wɔ ɛno mu.

Yɛnya saa phosphorus/phosphate yi firi aduane a yɛdi mu.

Nea ɛho hia no, phosphate dodow a ɛwɔ yɛn mogya mu no ne calcium dodow a ɛwɔ yɛn mogya mu no wɔ abusuabɔ tẽẽ. Wɔn baanu no yɛ adwuma wɔ ɔkwan a ɛne no bɔ abira so. Ɛne sɛ, bere a calcium dodow a ɛwɔ mogya no mu kɔ soro no, phosphate dodow so tew. Eyi rekɔ so sekan biara. Parathyroid hormone (PTH) a parathyroid ntini a ɛwɔ yɛn kɔn mu na ɛyɛ no na ɛhwɛ saa calcium ne phosphate dodow yi so.

Saa tebea yi abu so dɛn (Hypophosphatemia)?

Hypophosphatemia a emu nyɛ den yɛ tebea a ɛtaa ba a wohu wɔ mogya mu nhwehwɛmu mu. Amanneɛbɔ ahorow bi kyerɛ sɛ ɛka nnipa a wɔwɔ United States no mu bɛyɛ 5%. Mpɛn pii no, ɛnyɛ tebea a emu yɛ den na ɛmfa yare no ho sɛnkyerɛnne biara mma. Wɔtaa hu no wɔ akwanhyia mu.

Nanso, hypophosphatemia a ɛba mpofirim a emu yɛ den (hypophosphatemia a emu yɛ den, a emu yɛ den) abu so kɛse wɔ nnipa a wɔwɔ ayaresa tebea horow bi mu. Nhwɛsoɔ:

• Wɔn a nsanom ayɛ wɔn su `(Alcohol use disorder)`
• Wɔ ketoacidosis (DKA) a ɛde asikreyare ba ho no .
• Wɔ ɔyare mmoawa a emu yɛ den mu no, sepsis
• Wɔn a wɔahyew kɛse no fam

Wobetumi ahu saa tebea yi wɔ nnipa a wɔte sɛ eyi mu bɛyɛ 80% mu.

Enti, dɛn ne `(Hypophosphatemia)` ho sɛnkyerɛnne?

Nsɛnkyerɛnne no gyina sɛnea phosphate dodow no sua so.

Hypophosphatemia a Ɛnyɛ Den

Mpɛn pii no, nnipa a wɔwɔ hypophosphatemia a emu nyɛ den no nni sɛnkyerɛnne biara , nanso ebinom betumi anya ntini mu mmerɛwyɛ kakra na wɔabrɛ.

Sɛ emu yɛ den a (Severe Hypophosphatemia) .

Nanso, sɛ phosphate dodow sua koraa (hypophosphatemia a emu yɛ den) a, sɛnkyerɛnne ahorow a edidi so yi betumi aba, na ɛnsɛ sɛ wobu eyinom adewa :

• Ɛyaw a ɛba ntini ne nnompe mu
• Ntini mu mmerɛwyɛ a emu yɛ den
• Nsakrae a ɛba adwene mu - sɛ nhwɛso no, wontumi mfa n’adwene nsi biribi so, ɛnyɛ den sɛ obi bo fuw
• Ɔhome anaa koma a entumi nyɛ adwuma yiye
• Mmerewa a wɔte nka, sɛnea wɔyɛ wɔn ade no so tew
• Sɛ obi nya akisikuru (akisikuru) .

Eyi ho hia yiye: Sɛ wɔansa hypophosphatemia a emu yɛ den no ntɛm a , ebetumi ama obi akɔ komayare na owu mpo . Enti sɛ wo anaa obi a wunim no wɔ saa sɛnkyerɛnne ahorow a emu yɛ den yi a, ɛsɛ sɛ wokɔ ayaresabea a ɛbɛn wo ntɛm ara.

Sɛ ɛwɔ hɔ bere tenten a (Chronic Hypophosphatemia) .

Nnipa a phosphate dodow sua bere tenten (chronic hypophosphatemia) betumi anya sɛnkyerɛnne ahorow te sɛ:

• Ɛyaw a ɛba nnompe mu
• Nnompe a ɛpaapae
• Mrɛyɛ
• Akɔnnɔ

Mmofra nkumaa a phosphate dodow sua bere tenten no betumi anya tebea bi a wɔfrɛ no rickets , a nea ɛka ho ne:

• Ɔsorokɔ a wɔhwere esiane mfe a obi adi nti
• Nan no a ɛyɛ kurukuruwa te sɛ bow
• Nsateaa ne nansoaa no mmeae a ɛtrɛw esiane nsakrae a ɛba nnompe mu nti

Sɛ wo anaa wo ba wɔ saa sɛnkyerɛnne yi bi a, ɛho hia paa sɛ wobɛhwehwɛ aduruyɛfoɔ afotuo.

Dɛn ne nneɛma a ɛde `(Hypophosphatemia)` ba?

Nneɛma pii nti na tebea yi betumi aba. Ɛsono nea ɛde ba no gyina sɛ ebia ɛnyɛ den anaasɛ emu yɛ den, mpofirim, anaasɛ ɛtra hɔ kyɛ so.

Nneɛma a ɛde hypophosphatemia a ɛkɔ fam ne nea emu yɛ den ba

Phosphate a enni nipadua no mu a ɛkɔ fam kosi nea emu yɛ den betumi aba wɔ tebea horow a edidi so yi mu:

• Bere a obi ho retɔ no wɔ asikreyare ketoacidosis (DKA) mu no .
• Nsã a wɔnom ne nsa a wɔtwe wɔn ho fi ho
• Ɔhyew a emu yɛ den
• Refeeding syndrome : Eyi yɛ nea ɛyɛ den kakra. Sɛ yɛbɛka no tiawa a, ɛyɛ aduan a wɔsan kɔ mpofirim wɔ mmuadadi bere bi akyi, na ɛma nsu ne anyinam ahoɔden dodow a ɛwɔ nipadua no mu no sesa a ɛyɛ hu, na ɛtɔ mmere bi a ɛde nkwa to asiane mu.
• Ɔhome mu alkalosis a emu yɛ den: Eyi ne bere a carbon dioxide a ɛdɔɔso nni mogya no mu.

Nneɛma a ɛde hypophosphatemia a ɛtra hɔ kyɛ ba

• Parathyroid hormone dodow a ɛkɔ soro, sɛ nhwɛso no wɔ tebea ``Hyperparathyroidism`` mu.
• Nkwammoaa afoforo a ɛnkari pɛ, te sɛ Cushing yare.
• Vitamin D a enni nipadua mu.
• Malabsorption yɛ tebea a aduan ntumi nkɔ nipadua no mu yiye esiane aduan pa a wonnya nni ne dwensɔtwaa mu haw ahorow nti.
• Electrolyte afoforo a ɛnkari pɛ, te sɛ magnesium a ɛba fam (hypomagnesemia) ne potassium a ɛba fam (hypokalemia).
• Ayaresa a wɔde sa dade a enni nipadua mu ne dade a wɔde fa IV mu, titiriw nea wɔfrɛ no ferric carboxymaltose (FCM). Eyi taa ba bere a wɔkɔ so nom dade wɔ saa kwan yi so no.
• Nnuru a wɔde siw nsu mu a wɔde bedi dwuma bere tenten.
• Nnuru a ɛko tia acid a ɛkyekyere phosphate a wɔtaa de di dwuma anaasɛ ɛboro so, a wɔtɔ fi nnurutɔnbea a wonni aduruyɛ mu afotu. Nea ɛka eyi ho ne nnuru a ekum asikre a aluminium, calcium, ne magnesium wom.
• Aduru bi a wɔfrɛ no theophylline a wɔde ma mmea a wɔyem no awuduru.

Nnipa a wɔwɔ asaabo mu yare a akɔ anim (titiriw wɔn a wɔreyɛ dialysis) nom nnuru a wɔfrɛ no "phosphate binders" ka aduan ho, a wɔn asaabo ho ɔbenfo kyerɛw ma wɔn, na ama phosphate a wɔtwe fi aduan mu no ano brɛ ase. Eyinom nso betumi ama phosphate dodow akɔ fam sɛ wɔde di dwuma bere tenten a.

Ɔkwan bɛn so na wohu saa tebea yi `(Hypophosphatemia)`?

Eyi yɛ mmerɛw yiye sɛ wobehu. A doctor will do a blood test to check the level of phosphate in your blood . Sɛ wo mogya mu phosphate dodow nnu miligram 2.5 wɔ deciliter biara mu (mg/dL) a, wɔka sɛ wowɔ ``Hypophosphatemia''.

Phosphate dodow a ɛfata wɔ mogya mu ma mpanyimfo no yɛ 2.5 kosi 4.5 mg/dL, na mmofra fam no, ɛyɛ 4.5 kosi 6.5 mg/dL. Nanso, saa gyinapɛn ahorow yi betumi ayɛ soronko kakra wɔ lab biara mu.

Mpɛn pii no, titiriw wɔ hypophosphatemia a emu yɛ den mu no, wobetumi agyina w’ayaresa ho abakɔsɛm ne wo sɛnkyerɛnne ahorow so ahu nea ɛde ba no pefee.

Esiane sɛ mpɛn pii no, hypophosphatemia fi aduruyɛ mu tebea foforo mu nti, wo duruyɛfo betumi ahyɛ sɛ wɔnyɛ nhwehwɛmu foforo na ama wɔahu nea ɛde ba na wɔahwɛ w’akwahosan nyinaa mu. Ebia eyinom bi ne:

• Mogya mu nhwehwɛmu afoforo: Asaabo dwumadi mu nhwehwɛmu, calcium mogya mu nhwehwɛmu, vitamin D mogya mu nhwehwɛmu.
• Nsu mu nhwehwɛmu.
• Ebia mfoninitwa scan ahorow.

Dɛn ne ayaresa a wɔde sa `(Hypophosphatemia)`?

Ayaresa titiriw ne sɛ wɔbɛsa nea ɛde tebea yi ba titiriw, bere a wɔsan de phosphate dodow a ɛwɔ mogya no mu no nso ba.

Wɔtaa ma nnipa a wɔwɔ hypophosphatemia a emu nyɛ den kosi nea ɛkɔ fam nnuru a wɔnom de si phosphate ananmu . Ebia wo duruyɛfo nso bɛkamfo akyerɛ sɛ di nnuan a phosphorus pii wom.

Nanso sɛ tebea no mu yɛ den a, wɔde phosphate fa ntini mu (denam IV so) .

So biribi wɔ hɔ a yebetumi ayɛ de asiw tebea yi ano?

Nokwarem no, ɛnyɛ hypophosphatemia nyinaa na wobetumi asiw ano, titiriw nea emu yɛ den na ɛba mpofirim no. Nanso, aduan a ahoɔden wom na ɛkari pɛ a wobedi no betumi akɔ ɔkwan bi so ma wɔasiw phosphate dodow a ɛnyɛ den ano.

Nnuan bɛn na phosphorus pii wom?

• Nam, mpataa ne protein afoforo: Afã horow te sɛ nkesua, akokɔ, akokɔnam, mprako nam, ɛpo mu nnuan, ne mmerɛbo.
• Nufusu a wɔde yɛ nneɛma: nufusu, kyiisi, cottage cheese, yogurt.
• Nnuadewa ne aba: almond, cashews, Brazil nnuaba, akutu aba, sesame aba.

Nea ɛho hia: Ansa na wobɛyɛ nsakrae kɛse biara wɔ w’aduan mu no, hwɛ hu sɛ wo ne oduruyɛfo anaa aduannuru ho ɔbenfo bɛkasa.

Sɛ wowɔ tebea bi a ɛde wo to asiane kɛse mu sɛ wubenya hypophosphatemia, te sɛ hyperparathyroidism, nsɛm a ɛfa sɛnea obi ntumi nnye nsu, anaa vitamin D a wunni ho a, ɛho hia sɛ wokɔ wo duruyɛfo nkyɛn daa na wudi w’ayaresa nhyehyɛe no akyi. Eyi betumi aboa ma wɔasiw hypophosphatemia ano.

Dɛn na ɛbɛba daakye? (Nkɔmhyɛ) .

Tebea yi ho nkɔmhyɛ gyina sɛ ebia ɛnyɛ den anaasɛ emu yɛ den, efi ase mpofirim, anaasɛ ɛtra hɔ kyɛ so. Mpɛn pii no, nsɛm a emu nyɛ den no yɛ wɔn ade yiye bere a wɔde sa yare no, a ɛkyerɛ sɛ wobetumi asa wɔn yare. Nanso, nsɛm a emu yɛ den a efi ase mpofirim no betumi de nsɛnnennen a emu yɛ den aba sɛ wɔansa no ntɛm a.

So nsɛnnennen betumi aba esiane `(Hypophosphatemia)` nti?

Yiw, sɛ wɔansa, titiriw sɛ phosphate (hypophosphatemia a enni sabea) so tew bere tenten a, tebea bi a wɔfrɛ no osteomalacia betumi aba. Sɛ yɛbɛka no tiawa a, eyi ne bere a nnompe no yɛ mmerɛw na ɛbubu ntɛmntɛm .

Sɛnea yɛadi kan aka no, sɛ wowɔ hypophosphatemia ho sɛnkyerɛnne a emu yɛ den, te sɛ ntini mu yaw a wontumi nkyerɛkyerɛ mu ne nsakrae a ɛba w’adwene mu a, ɛho hia yiye sɛ wokɔ ayaresabea a ɛbɛn wo ntɛm ara sɛnea wubetumi.

Nea etwa to no, kae eyi.

Enti, saa phosphate yi a yɛkaa ho asɛm nnɛ no yɛ ``electrolyte`` a ɛho hia yiye wɔ yɛn mogya mu. Wobetumi ahu phosphate a ɛso tew kakra (``mild hypophosphatemia``) wɔ mogya mu nhwehwɛmu mu na ɛnyɛ biribi a ɛsɛ sɛ ɛhaw adwene. Sɛ ɛba saa a, wo duruyɛfo bɛka akyerɛ wo sɛ di nnuan a phosphorus pii wom pii.

Nanso, sɛ wowɔ aduruyɛ mu tebea bi anaa su bi a ɛde wo to asiane mu sɛ phosphate a wunni kɛse te sɛ nsa a wobɛnom boro so anaasɛ wo dwensɔtwaa mu a ɛnyɛ yiye a, ɛbɛyɛ papa sɛ wo ne wo duruyɛfo bɛkasa afa ho. Bisa wɔn sɛnea wobetumi asiw hypophosphatemia ano ne sɛnkyerɛnne ahorow a ɛsɛ sɛ wɔhwɛ yiye wɔ ho. Kae sɛ wo duruyɛfo yɛ w’adamfo paa wɔ w’akwahosan akwantu no mu. Wobetumi aboa wo.

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