So wunim ‘srade a ahintaw’ yi ho asɛm? Momma yensua Lipoprotein (a) ho ade!

Sɛ woyɛ wo mogya mu nhwehwɛmu sɛ ebia srade wom anaa a, ebia woahu din te sɛ LDL, HDL, ne triglycerides wɔ amanneɛbɔ a wunya no mu, ɛnte saa? Yɛtaa ka "srade pa" (HDL) ne "srade bɔne" (LDL) ho asɛm. Nanso biako wɔ hɔ a enni list no mu a obiara ka ho asɛm, ahintaw kakra, nanso ebetumi anya koma akwahosan so nkɛntɛnso kɛse. Ɛno ne Lipoprotein (a) , anaa Lp(a) tiawa. Ɛte sɛ abusua mu ahintasɛm, na ɛtɔ mmere bi a yebetumi de ɔhaw akɛse aba yɛn nipadua mu a yennim.

Sɛ yɛbɛka no tiawa a, dɛn ne Lipoprotein (a)?

Okay, momma yɛmfa no saa kwan yi so. Lipoprotein (a) yɛ LDL (Low-Density Lipoprotein) bi, a wɔsan frɛ no “srade bɔne.” Sɛ LDL srade kɔ soro wɔ nipadua no mu a, dɛn na ɛba? Ɛboaboa ano wɔ yɛn mogya ntini no afasu so, na ɛyɛ abopon a ɛte sɛ ahoɔhare a ɛbɔ wɔ kwan so. Wɔ nnuruyɛ mu no, yɛfrɛ saa abopon yi . Bere a ahoɔhare a ɛbɔ yi dɔɔso no, mogya no ntumi nkɔ yiye. Awiei koraa no, eyinom betumi asiw mogya ntini no mu koraa na ama mogya no agyae. Eyi yɛ ade titiriw a ɛde komayare ne akisikuru ba.

Afei, ade titiriw a ɛwɔ Lp(a) ho ne sɛ ɛyɛ aniberesɛm kakra sen LDL. Nneɛma abien nti na ɛte saa:

1. Mogya no tu ntɛmntɛm: Lp(a) mu nneɛma nketenkete boa ma yɛn mogya tu ntɛmntɛm sen sɛnea ɛte daa.

2. Ɛma mogya a ɛretu no ntumi nkɔ: Ɛsan nso siw mogya a ɛretu a ayɛ no ano.

Fa no sɛ, srade (plaque) bi ayɛ wɔ mogya ntini bi mu. Sɛ saa ɔfa no pae esiane Lp(a) nti a, hokwan kɛse wɔ hɔ sɛ mogya a ɛbɛtɔ ntɛmntɛm na asiw mogya ntini no ano koraa. Ɛno nti na ɛsɛ sɛ yɛhwɛ yiye titiriw wɔ Lp(a) ho no.

So Lp(a) level yɛ biribi a efi awosu mu nkwaadɔm mu?

Aane. Ɛte saa. Eyi ne ade a ɛho hia sen biara na ebia ɛyɛ awerɛhow kakra wɔ eyi ho. Wo Lp(a) dodow no gyina awosu mu nkwaadɔm a wunya fi wo maame ne wo papa hɔ. Eyi kyerɛ sɛ ɛmfa ho sɛnea woteɛteɛ w’apɔw mu anaasɛ wohwɛ w’aduan so yiye no, wuntumi ntew wo Lp(a) dodow so kɛse. Ɛda adi sɛ Lp(a) dodow a wowɔ bere a woyɛ abofra no bɛyɛ wo de wo nkwa nna nyinaa.

Mɛyɛ dɛn ahu me Lp(a) level?

Wobetumi de mogya mu nhwehwɛmu a ɛnyɛ den ahu eyi. Nanso ade ketewaa bi wɔ ha. Mpɛn pii no, woyɛ srade mu nhwehwɛmu, a wɔfrɛ no Lipid Profile.Nokwarem no, wɔmfa saa Lp(a) dodow yi nsusuw ho. Ɛsɛ sɛ wɔyɛ no wɔ ɔkwan soronko so, titiriw denam bisa a wɔbɛsrɛ so. Wo duruyɛfo betumi asi gyinae sɛ wuhia na ɔde wo akɔma no.

Dɛn nti na oduruyɛfo bi bɛkamfo nhwehwɛmu yi akyerɛ?

Ɛnyɛ obiara na ohia nhwehwɛmu yi, nanso sɛ wowɔ nneɛma afoforo a ɛma asiane a ɛwɔ hɔ sɛ wubenya komayare no yɛ kɛse a, ebia wo duruyɛfo no besi gyinae sɛ ɔbɛhwɛ eyi nso mu.

Lp(a) levels ne nea ɛkyerɛ

Akwan abien na ɛwɔ hɔ a wɔfa so susuw Lp(a) dodow. Biako ne sɛ wobesusuw Lp(a) dodow a ɛwɔ mogya no mu. Wɔde gyinapɛn ahorow no ama wɔ miligram mu wɔ deciliter biara mu (mg/dL). Ɔfoforo no ne sɛ wobesusuw Lp(a) nneɛma nketenkete dodow a ɛwɔ mogya no mu. Wɔde gyinapɛn ahorow no ama wɔ nanomoles mu wɔ lita biara mu (nmol/L). Ɛho hia sɛ wubisa wo duruyɛfo no unit ahorow a wo amanneɛbɔ no wɔ mu.

Yɛtaa kyekyɛ mg/dL gyinapɛn ahorow mu sɛnea edidi so yi:

• Sɛnea ɛte daa: Ennu 30 mg/dL.
• Asiane a ɛwɔ ɔhye so: Ɛwɔ 30 mg/dL ne 50 mg/dL ntam.
• Asiane kɛse: Bɛboro 50 mg/dL.

Wɔ nmol/L mu no, wobu bo a ɛboro 100 nmol/L sɛ asiane kɛse.

Wo Lp(a) dodow a ɛkɔ soro no kyerɛ sɛ wowɔ asiane kɛse mu sɛ wubenya komayare ne mogya ntini mu yare, sɛ mpo wo srade afoforo no ye a.

Nhwehwɛmu ada no adi sɛ Lp(a) dodow a ɛkɔ soro no ne nyarewa yi wɔ abusuabɔ tẽẽ:

• Koma mu yare
• Koma mu yare
• Nnwodwoɔ
• Aortic valve a ɛyɛ mmerɛw
• Ntini a ɛwɔ nipadua no akyi (PAD) .

So sɛnkyerɛnne ahorow bi wɔ hɔ a ɛkyerɛ sɛ Lp(a) dodow kɔ soro?

Dabi, ɛno ne ɔfã a ɛyɛ hu no. Nnipa pii a wɔwɔ Lp(a) dodow a ɛkɔ soro no nkyerɛ yare no ho sɛnkyerɛnne biara. Wonnim sɛ wɔwɔ asiane mu kosi sɛ biribi a anibere wom te sɛ komayare bɛba. Ɛno nti, sɛ wowɔ abusua abakɔsɛm a ɛkyerɛ sɛ wowɔ komayare a, ɛho hia yiye sɛ wo ne wo duruyɛfo kasa fa ho ntɛm na sɛ ɛho hia a, woyɛ ho nhwehwɛmu.

Okay, afei yɛbɛyɛ dɛn atew saa Lp(a) yi so?

Eyi yɛ asɛmmisa a obiara wɔ. Sɛ yɛbɛka nokware a, mprempren aduru pɔtee biara nni hɔ a wɔapene so sɛ wɔde bɛto Lp(a) dodow so na akɔ fam. Nhwehwɛmufo reyɛ nnuru foforo pii a wɔde bɛyɛ eyi na wɔresɔ ahwɛ. Enti yɛwɔ anidaso sɛ daakye a enni akyiri benya ano aduru pa.

Ɛwom sɛ yentumi ntew Lp(a) dodow so tẽẽ de, nanso ade a eye sen biara a yebetumi ayɛ ne sɛ yebedi nneɛma afoforo a ɛma komayare ho asiane yɛ kɛse nyinaa so . Ɔkwan foforo so no, sɛ Lp(a) nkutoo ne tuo a yɛwɔ a, ɛte sɛ nea yɛredi afoforo no nyinaa adwuma.

Nneɛma a wubetumi ayɛ:

• Gyae tawa ho nneɛma a wode di dwuma koraa. Sigaretnom ne ade kɛse a ɛsɛe mogya ntini.
• Yɛ apɔw-mu-teɛteɛ daa. Yɛ biribi te sɛ nantew anaa mmirikatu anyɛ yiye koraa no simma 30, nnafua 5 dapɛn biara.
• Kura mu duru a ɛfata mu.
• Fa aduan a ɛma koma nya ahoɔden tom. Di ngo, nkyene, ne asikre kakraa bi, na di nhabannuru, nnuaba, nhabannuru, ne nnuan a ahoɔdennuru wom pii.
• Ma wo mogya mmoroso ne asikreyare nni wo so. Fa nnuru a wo duruyɛfo akyerɛw ama eyinom no di dwuma pɛpɛɛpɛ.
• Di LDL srade dodow a ɛwɔ nipadua mu no so. Ɛwom sɛ ɛrentumi nyɛ yiye sɛ wɔbɛtew Lp(a) so de, nanso nnuru a ɛtew LDL srade so te sɛ statin anaa PCSK9 inhibitors , betumi atew asiane no nyinaa so kɛse.
• Di adwennwen so.

Ɛdenam asiane a ɛwɔ hɔ so no, wo duruyɛfo betumi akyerɛw aduru bi te sɛ aspirin ama wo na ama mogya a ɛtwetwe no so atew.

Wɔ wɔn a Lp(a) dodow kɔ soro yiye, titiriw wɔn a wɔwɔ Family Hypercholesterolemia fam no, aduru bi wɔ hɔ a wɔfrɛ no Apheresis . Eyi te sɛ dialysis bere a asaabo no di nkogu no. Wɔde wo abɔ afiri bi ho na wɔayi Lp(a) nketenkete no fi mogya no mu. Nanso, eyi yɛ ayaresa a egye nnɔnhwerew pii, ehia sɛ wɔyɛ no pɛnkoro anaa mprenu dapɛn biara, na wɔyɛ ma ayarefo a wɔyɛ soronko koraa nkutoo.