Ebia wunim sɛnea calcium ho hia na ama yɛn nnompe ne yɛn sẽ ayɛ den dedaw. Nanso so wunim sɛ ɛsɛ sɛ calcium, aboɔden abo a ɛho hia no nso yɛ nea ɛfata na ama mogya ntini, ntini, ne ntini a ɛyɛ den no akɔ so ayɛ yiye? Sɛ nea efii wo mogya mu nhwehwɛmu nnansa yi mu bae no kyerɛ sɛ calcium dodow a ɛwɔ wo mu no dɔɔso dodo anaasɛ ɛba fam dodo a, ebia wo duruyɛfo no ahyɛ sɛ ɔsan nyɛ mogya mu nhwehwɛmu titiriw foforo. Ɛno ne sɔhwɛ a yɛreka ho asɛm nnɛ, a ɛkyerɛ wo parathyroid hormone (PTH) dodow.
Sɛ yɛbɛka no tiawa a, dɛn ne parathyroid hormone (PTH)?
Yɛwɔ ntini nketenkete anan paa wɔ yɛn kɔn mu. Wɔn kɛse bɛyɛ sɛ peas nketewa. Eyinom ne nea yɛfrɛ no
parathyroid ntini ahorow . Saa ntini ahorow yi na ɛma parathyroid hormone anaa PTH. Dwumadi titiriw a saa hormone yi yɛ ne sɛ ɛbɛhwɛ calcium dodow a ɛwɔ yɛn mogya mu no so. Ɛyɛ nhyehyɛe a ɛyɛ nwonwa yiye. Susuw ho saa kwan yi so:
- Sɛ wo mogya mu calcium dodow so tew , saa ntini ahorow yi yi hormone PTH no kɔ wo mogya mu. Saa PTH yi kɔboaboa calcium fi wo nnompe ne w’asaabo mu na ɛma wo calcium dodow san ba sɛnea na ɛte kan no.
- Sɛ wo mogya mu calcium dodow kɔ soro a , saa ntini ahorow yi gyae PTH hormone no gyae. Eyi hwɛ calcium dodow a ɛwɔ wo mogya mu no so.
Enti, sɛ wosusuw wo PTH dodow a, ɛboa kɛse ma nnuruyɛfo ma wohu nea ɛma wo mogya mu calcium so tew anaasɛ ɛkɔ soro ankasa.
Dɛn nti na oduruyɛfo bi bɛkamfo nhwehwɛmu yi akyerɛ?
Ade titiriw ne sɛ wubehu sɛ ebia nea ɛde wo mogya mu calcium dodow a ɛnteɛ ba no yɛ ɔhaw a ɛfa parathyroid ntini ahorow no dwumadi ho anaasɛ biribi foforo a ɛde ba. Sɛ wo PTH dodow ne wo calcium dodow hyia a, ɛkyerɛ sɛ nea ɛde calcium dodow a ɛnteɛ ba no yɛ biribi foforo. Mpɛn pii no, sɛ wowɔ sɛnkyerɛnne ahorow a edidi so yi a, ebia wo duruyɛfo bɛkamfo PTH nhwehwɛmu yi akyerɛ wo.
| Hypercalcemia - a ɛma calcium kɔ soro wɔ mogya mu | Hypocalcemia - calcium a esua wo mogya mu |
|---|
| Yafunu mu yaw | Adwenemhaw ne adwene a ɛtaa sakra |
| Sukɔm a ɛtra so | Ntini a ɛtwetwe anaa ɛtwetwe (Spasms) . |
| Ɛho hia sɛ wɔtaa tow nsu | Nsa, anan, ne ano a ɛyɛ mmerɛw anaasɛ ɛyɛ mmerɛw |
| Akisikuru ne ɔfe | Koma a ɛbɔ a ɛnyɛ ne kwan so |
| Ɔbrɛ | |
| Nipadua ne nnompe mu yaw | |
| Asaabo mu abo | |
So asiane bi wɔ sɔhwɛ yi mu?
Nokwarem no,
asiane kakraa bi pɛ na ɛwɔ mu. Sɛnea ɛte wɔ mogya mu nhwehwɛmu biara ho no, ebia wobɛte ɛyaw bi nka wɔ baabi a wɔde ade no ahyɛ mu no. Ebia wubenya akuru bi nso wɔ ɛno akyi. Ebia nnipa binom bɛte nka sɛ wɔn adwene atu afra kakra bere a wɔde mogya ama akyi. Nanso eyi yɛ ade a ɛfata koraa.
Mfaso kɛse a ɛwɔ sɔhwɛ yi so ne sɛ ɛma oduruyɛfo no hu pɛpɛɛpɛ sɛ ebia wo nipadua no reyɛ PTH hormone pii dodo anaasɛ kakraa bi dodo.
Eyi betumi asi parathyroid yare bi so dua anaasɛ ayera. Afei wo ne wo duruyɛfo betumi ahwehwɛ nneɛma afoforo a ɛde calcium dodow a ɛnteɛ ba.
So ɛsɛ sɛ wusiesie wo ho ansa na woayɛ sɔhwɛ no?
Yiw, ebia wo duruyɛfo bɛka akyerɛ wo sɛ gyae nnuru anaa vitamin (nneɛma a wɔde ka ho) bi a wobɛnom da a edi nhwehwɛmu no anim anaa da a wobɛyɛ no. Nanso
nnyae nnuru biara a wobɛnom da a wunni kan mmisa wo duruyɛfo .
Dɛn na ɛba bere a wɔreyɛ sɔhwɛ no ne bere a wɔawie no?
Eyi yɛ adeyɛ a ɛyɛ mmerɛw yiye. Woyi mogya kakraa bi fi ntini bi a ɛwɔ wo nsa mu mu. Onipa a ɔregye mogya no bedi kan de rɔba abɔ wo basa no atifi na wakyekye mu denneennen. Sɛ wopia wo basa a, mogya ntini no bɛda adi pefee. Afei, wɔde ade ketewaa bi bɛtwe mogya kakraa bi akɔ afiri bi a wɔde yɛ nhwehwɛmu mu. Eyi nhia mogya pii. Sɛ wɔtwe mogya no a, woyi afiri no na wɔde plaster ketewaa bi gu baabi a ɛwɔ no. Afei wɔde mogya yi kɔ aduruyɛdan mu kɔhwɛ sɛnea PTH, calcium, ne ebia nkwaadɔm ne mineral afoforo te.
Ɔkwan bɛn so na yɛbɛte nea efi mu ba no ase?
Ebetumi agye nna kakraa bi ansa na sɔhwɛ mu aba asan aba. Nanso ɛtɔ mmere bi a wobetumi anya nea efi mu ba ntɛmntɛm, a egyina aduruyɛdan ne oduruyɛfo no ahiade so. Wɔde picograms na ɛkyerɛ nea efi mu ba no wɔ mililita biara mu (pg/mL). PTH dodow a ɛfata no betumi ayɛ soronko kakra wɔ lab biara mu. Akwahosan kwan a ɛwɔ hɔ ma `intact molecule` type of PTH no taa yɛ
10 - 65 pg/mL .
Ade a ɛho hia sen biara ne sɛ akyinnye biara nni ho sɛ wo ne wo duruyɛfo bɛkasa na ama woate nea akontaahyɛde ahorow a ɛwɔ nea efi mu ba no kyerɛ ase ankasa.
PTH dodow ne nea ɛde ba Nneɛma a ebetumi ama PTH dodow akɔ soro (Hyperparathyroidism): Nneɛma a ebetumi ama PTH dodow akɔ fam (Hypoparathyroidism):
So ɛsɛ sɛ meyɛ sɔhwɛ pii?
Yiw, ebia wo duruyɛfo bɛkamfo akyerɛ sɛ wɔnyɛ nhwehwɛmu foforo a egyina wo PTH ne calcium dodow so.
- Sɛ nhwɛso no, sɛ wo PTH dodow dɔɔso nanso wo calcium dodow sua a, ebetumi akyerɛ sɛ wo parathyroid ntini no reyɛ adwuma yiye. Afei wo duruyɛfo bɛhwɛ wo vitamin D, phosphorus, ne magnesium dodow mu ahwɛ sɛ ɛrenya wo calcium dodow so nkɛntɛnso anaa.
- Ɔkwan foforo so no, sɛ wo calcium dodow dɔɔso na wo PTH dodow dɔɔso sen sɛnea ɛte daa a, ebia wubenya hyperparathyroidism. Sɛ ɛba saa a, wo duruyɛfo no bɛyɛ X-ray anaa mfoninitwa nhwehwɛmu foforo de ahwɛ wo parathyroid ntini no mu.
Sɛ ntini no ahonhon anaasɛ ɛwɔ akisikuru a, wobetumi ayɛ oprehyɛn de ayi ntini no afi hɔ. Nanso, sɛ wo tebea no mu nyɛ den na wunni sɛnkyerɛnne ahorow te sɛ asaabo mu haw anaa nnompe a ɛyɛ mmerɛw a, ebia wo duruyɛfo bɛpɛ sɛ ɔhwɛ wo calcium ne PTH dodow daa. Wobetumi nso akyerɛw aduru bi te sɛ Cinacalcet (Sensipar) ama obi. Wɔ nsɛm a ɛtete saa mu no, ebia ɛho renhia sɛ wɔyɛ oprehyɛn.
Nkrasɛm a Wɔde Kɔ Fie
- PTH mogya mu nhwehwɛmu yɛ nhwehwɛmu a ɛho hia a wɔde hwehwɛ nea ɛde calcium dodow a ɛnteɛ ba wo mogya mu.
- Eyi yɛ mogya mu nhwehwɛmu a wɔyɛ no daa a asiane kakraa bi na ɛwom, enti ɛho nhia sɛ wusuro.
- Wo duruyɛfo begyina wo sɛnkyerɛnne ahorow, calcium dodow, ne PTH dodow so asi nea ɔbɛyɛ akyi no ho gyinae.
- Sɛ wo nsa ka wo nhwehwɛmu no aba a, hwɛ hu sɛ wo ne wo duruyɛfo bɛkasa na wate ase yiye.
- Mma nnnyae wo nnuru nonom anaasɛ nsakra dodow a wode di dwuma no da a wunnya wo duruyɛfo afotu.
Parathyroid hormone, PTH nhwehwɛmu, calcium, mogya mu nhwehwɛmu, hypercalcemia, hypocalcemia, asaabo mu yare
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