Yɛn nyinaa nim sɛ kokoram a yɛbɛko atia no nyɛ mmerɛw. Wɔ ɔko yi mu no, wo nnuruyɛfo bɛkamfo ayaresa ahorow te sɛ nnuru a wɔde sa yare akyerɛ wo. Pegaspargase (ahyɛnsode: Oncaspar) yɛ nnuru a ɛho hia na tumi wom sen biara a wɔde sa mogya mu kokoram bi a wɔfrɛ no acute lymphoblastic leukemia (ALL) no mu biako . Enti, sɛ wɔde aduru yi rema wo anaa wo dɔfo bi a, ɛbɛyɛ ahotɔ kɛse ama wo sɛ wubenya ntease a ɛnyɛ den na emu da hɔ wɔ biribiara a ɛfa ho no ho. Momma yɛnka eyi ho asɛm.
Aduru bɛn na Pegaspargase yɛ?
Sɛ yɛbɛka no tiawa a, Pegaspargase yɛ nnuru a wɔde sa yare, kyerɛ sɛ, aduru a wɔde kum kokoram nkwammoaa . Asparagine yɛ aduannuru a ɛho hia ma kokoram nkwammoaa nyin. Nea Pegaspargase yɛ ne sɛ ɛpaapae saa asparagine aduannuru yi a ɛwɔ nipadua no mu, na ɛma kokoram nkwammoaa no nnya "aduan". Afei kokoram nkwammoaa no ntumi nnyin na wowuwu.
Ɛwom sɛ wɔde sa Acute Lymphoblastic Leukemia (ALL) titiriw de, nanso ɛtɔ mmere bi a wobetumi de adi dwuma ama kokoram ahorow afoforo sɛnea wo duruyɛfo kamfo kyerɛ no.
Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo ansa na woafi ayaresa ase
Ansa na wubefi saa ayaresa yi ase no, ɛho hia yiye sɛ woka w’akwahosan ho abakɔsɛm nyinaa kyerɛ wo duruyɛfo. Ebia saa aduru yi ne akwahosan tebea horow bi bedi nkitaho. Hwɛ hu sɛ wobɛka nneɛma yi ho asɛm titiriw akyerɛ wo duruyɛfo:
- Allergies: Hwɛ hu sɛ wobɛka akyerɛ yɛn sɛ wowɔ allergy bi wɔ Pegaspargase, L-asparaginase, E. coli proteins, nnuru afoforo, nnuan, anaa nnuru a wɔde yɛ nneɛma ho a.
- Pancreatitis: Sɛ woanya pancreatitis pɛn a.
- Mmɛn mu yare: Sɛ wowɔ mmerɛbo mu yare biara a.
- Mogya a ɛtwetwe ho haw ahorow: Sɛ wo mogya tu ntɛmntɛm anaasɛ wowɔ mogyatɔw ho haw ahorow a.
- Asikreyare: Sɛ wowɔ asikreyare anaa ɔhaw afoforo a ɛfa asikre dodow a ɛwɔ wo mogya mu ho a.
- Nyinsɛn: Ɛho hia sɛ woka kyerɛ wo duruyɛfo sɛ woanyinsɛn, worebɔ mmɔden sɛ wubenyinsɛn, anaa worenom nufu a. Eyi ho hia paa.
Ma wo duruyɛfo no nkyerɛw nnuru afoforo a wonom nyinaa, a vitamin, nnuru a wɔde di dwuma wɔ amanne kwan so, ne nnuru a wɔde ka aduan ho ka ho.
Ɔkwan bɛn so na wɔde aduru yi ma nipadua no?
Eyi nyɛ aduru a wubetumi de akɔ fie. Wɔde ma wɔ ayaresabea anaa ayaresabea., a oduruyɛfo anaa ayarehwɛfo adwumayɛfo a wɔanya ntetee titiriw wɔ eyi mu nkutoo na wɔyɛe.
Akwan abien na ɛwɔ hɔ a wɔfa so de aduru no ma:
1. Ntini a wɔde hyɛ nipadua no mu: Wɔde aduru bi , te sɛ nkyene, de nkakrankakra fa ntini bi mu kɔ nipadua no mu.
2. Intramuscular injection: Wɔde twitwiw ntini bi mu.
Wɔde eyi ma mmofra nkumaa, nkokoaa a wɔadi ɔsram biako mpo, wɔ tebea horow bi a wɔapaw mu. Nanso, mmofra oduruyɛfo na osi gyinae.
Nneɛma bɛn na ɛsɛ sɛ wususuw ho bere a wɔreyɛ ayaresa no?
Wo duruyɛfoɔ bɛhwɛ wo yie paa berɛ a worenom saa aduru yi.
- Mogya mu nhwehwɛmu: Ɛho behia sɛ woyɛ mogya mu nhwehwɛmu daa na ama woahu sɛnea aduru no renya wo nipadua no so nkɛntɛnso.
- Mogya mu asikre: Saa aduru yi betumi ama asikre dodow a ɛwɔ mogya mu no akɔ soro. Sɛ wowɔ asikreyare a, wo ne wo duruyɛfo nkasa mfa aduan a wudi ne sɛ ebia ɛsɛ sɛ wosakra wo asikreyare aduru no ho asɛm.
- Nneɛma a ɛma obi ho yɛ no hyew: Ɛtɔ mmere bi a, aduru yi ho adwenemhaw a emu yɛ den betumi aba. Sɛnea ɛbɛyɛ a asiane yi so bɛtew no, wo duruyɛfo betumi asi gyinae sɛ ɔbɛma wo nnuru afoforo (e.g. antihistamines, steroids) ansa na wama wo Pegaspargase.
- Nyinsɛn ne nufu a wɔde ma (CRITICAL): Eyi ho hia yiye.
- Mma nnyinsɛn esiane biribiara nti bere a worenom saa aduru yi **.
- Kwati sɛ wubenyinsɛn anyɛ yiye koraa no asram 3 bere a woagyae ayaresa no akyi .
- Akyinnye biara nni ho sɛ ɛsɛ sɛ wode awo ano aduru di dwuma wɔ saa bere yi mu. Nanso, esiane sɛ nnuru a wɔde siw nyinsɛn ano a hormone wom (nnuru a wɔde siw nyinsɛn ano) betumi ne saa aduru yi adi nkitaho nti, wo ne wo duruyɛfo nkasa mfa ɔkwan a ɛnyɛ hormone a wɔde siw nyinsɛn ano (e.g. kɔndɔm) a wode bedi dwuma ho.
- Sɛ wunya adwenem naayɛ ketewaa bi sɛ woanyinsɛn a, ka kyerɛ wo duruyɛfo ntɛm ara .
- Mma wo ba no nufu bere a wɔreyɛ ayaresa no ne ɔsram biako bere a woagyae no.
Nsunsuanso bɔne a ebetumi aba esiane nnuru nti
Te sɛ aduru biara no, Pegaspargase betumi de ɔhaw ahorow aba. Ɛnyɛ obiara na onya wɔn. Nanso, ɛho hia sɛ wohu saa sɛnkyerɛnne ahorow yi. Sɛ wuhu sɛnkyerɛnne bi a emu yɛ den a, ka kyerɛ nnuruyɛfo ntɛm ara anaa kɔ Dwumadibea a Ɛhwɛ Ntɛmntɛm (ETU) a ɛbɛn wo no nkyɛn .
| Side effect category | Nneɛma a ɛsɛ sɛ yɛhwɛ yiye wɔ ho |
|---|---|
| Nneɛma a ɛsɛ sɛ woka kyerɛ wo duruyɛfo anaa ayaresabea adwumayɛfo ntɛm ara | |
| Nneɛma a Ɛyɛ Den a Ɛma Nnipa Ho Yɛ Den | Honam ani akisikuru, ɛyaw, anim, ano anaa tɛkrɛma a ɛho ahonhon, ɛyɛ den sɛ wobɛhome. |
| Mogya a ɛretu ho sɛnkyerɛnne | Nsu tuntum a wɔde tarry ayɛ; nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; ɔfe a ɛte sɛ kɔfe a wɔayam anaasɛ ɛfe mogya; nsensanee kɔkɔɔ a ɛwɔ honam ani; mogya a ɛyɛ soronko a efi aniwa, anom, anaa hwene mu ba. |
| Mogya a Ɛtwetwe Nsɛnkyerɛnne | Koko mu yaw; ɛyɛ den sɛ wobɛhome; nan mu yaw, ɛho ahonhon, anaa ɔhyew. |
| Nsɛnkyerɛnne a ɛkyerɛ sɛ mmerɛbo asɛe | Nsu a ɛyɛ kɔkɔɔ anaa bruu tuntum; aniwa anaa honam ani a ɛyɛ kɔkɔɔ; huraeɛ; aduan ho akɔnnɔ a ɛyera; ɛyaw a ɛba yafunu no fã a ɛwɔ soro nifa so; nsu a ɛyɛ mmerɛw. |
| Asikre a ɛwɔ mogya mu a ɛkɔ soro ho sɛnkyerɛnne | Sukɔm ne ɔkɔm a ɛyɛ soronko; a wɔtaa tow nsu; ɔbrɛ a ɛtra so; anisoadehu a ɛyɛ kusuu. |
| Nsɛnkyerɛnne afoforo a emu yɛ den | Tiyɛ a emu yɛ den yiye, yafunu mu yaw a emu yɛ den (ebia ɛyɛ dwensɔtwaa mu yare ho sɛnkyerɛnne). |
| Sɛ ɛkɔ so anaasɛ ɛhaw adwene a, ka kyerɛ wo duruyɛfo. | |
| Nneɛma bɔne a ɛtaa ba | Fifiri, mu duru a ɛso tew. |
So ɔhaw ahorow betumi aba wɔ nnuru afoforo ho? (Nkitahodi ahorow) .
Aane. Nnuru bi betumi de ɔhaw aba bere a wɔde Pegaspargase ka ho no. Nhwɛsoɔ:
- methotrexate a wɔde di dwuma
- vincristine a wɔde yɛ aduru
- cytarabine a wɔde di dwuma
- dexamethasone a wɔde ma
- Nnuru a wɔde siw awo ano (nnuru a wɔde siw nyinsɛn ano) .
Saa list yi nwie pɛyɛ. Enti, ka nnuru biara a wobɛnom, vitamin mpo ho asɛm kyerɛ wo duruyɛfo . Afei nso, mma wo werɛ mmfi sɛ wobɛka akyerɛ no sɛ wonom sigaret anaa wonom nsa a.
Nkrasɛm a Wɔde Kɔ Fie
- Pegaspargase yɛ nnuru a ano yɛ den a wɔde sa mogya mu kokoram bi a wɔfrɛ no Acute Lymphoblastic Leukemia (ALL).
- Wɔde saa aduru yi ma wɔ ayaresabea nkutoo, wɔ aduruyɛfo hwɛ ase.
- Ansa na wubefi ayaresa ase no, ka w’ayaresa mu tebea horow, wo ho akisikuru, ne nnuru afoforo a wonom nyinaa ho asɛm kyerɛ wo duruyɛfo.
- Sɛ wuhu sɛnkyerɛnne ahorow te sɛ akisikuru a emu yɛ den, mogya a ɛretu, mogya a ɛtɔ, anaa yafunu mu yaw a emu yɛ den a, bɔ nnuruyɛfo amanneɛ ntɛm ara.
- Kwati nyinsɛn koraa bere a wɔreyɛ ayaresa no ne asram 3 wɔ ɛno akyi. Fa ɔkwan a wotumi de ho to so a ɛnyɛ hormone a wɔde siw awo ano di dwuma.
- Yɛsrɛ sɛ kɔ wo ayaresa nhyehyɛe a woayɛ ho nhyehyɛe no ase a worennyae beat biara. Sɛ woantumi ankɔ a, yɛsrɛ sɛ di kan bɔ ayaresabea no amanneɛ.
- Sɛ wowɔ nsɛmmisa anaa nsɛm bi a ɛhaw wo wɔ aduru yi ho a, wo ne wo duruyɛfo nka ho asɛm pefee.
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