Ɛyɛ den sɛ wobɛka nea wote nka bere a wuhu sɛ wowɔ kokoram no ho asɛm wɔ nsɛm mu. Nanso sɛ oduruyɛfo no ka ayaresa ho asɛm na wote nsɛm te sɛ ‘chemotherapy’ a, ɛyɛ ade a ɛfata sɛ wobɛte ehu nka kɛse mpo, wopɛ sɛ wuhu nneɛma pii, na w’adwene tu fra. Chemo nnuru a wɔtaa de sa kokoram no mu biako ne ‘Taxane.’ Ɛnnɛ, yɛbɛka eyi ho asɛm tiawa koraa, wɔ ɔkwan a wubetumi ate ase so, te sɛ nea wo ne w’adamfo paa bi rekasa.
Dɛn ankasa ne Taxane?
Sɛ yɛbɛka no tiawa a, taxanes yɛ nnuru a wɔde sa yare a ekum kokoram nkwammoaa na ɛma akisikuru nyin. Nea ɛka nnuru a wɔde sa yare ho ne sɛ yɛde nnuru yi bɛka yɛn mogya a ɛnam nipadua no nyinaa mu kɔhwehwɛ kokoram nkwammoaa na ɛsɛe no ho.
Nea ɛma saa nnuru a wɔde taxane yɛ yi yɛ soronko ne sɛ wonya fi awosu mu fi nnua mu. Wodii kan yii fii ‘Yew’ dua no ntini mu . Nokwarem no, taxanes yɛ nnuru ahorow abien a wɔde yɛ chemo a wonya fi afifide mu no mu biako. Ɔkwan foforo no ne nnuru kuw bi a wɔfrɛ no ‘Vinca alkaloids’, a wonya fi ‘Mella’ afifide mu.
Mprempren, nyansahufo reyɛ nnuru a ɛwɔ taxanes a wonya fi saa afifide yi mu no ho ade na wɔreyɛ adwuma mpo de ayɛ no wɔ aduruyɛdan ahorow mu.
Ɔkwan bɛn so na saa aduru yi kunkum kokoram nkwammoaa?
Sɛ yɛbɛte eyi ase a, ɛsɛ sɛ yedi kan te sɛnea kokoram nkwammoaa trɛw no ase. Kokoram trɛw denam kokoram nkwammoaa biako a wɔkyekyɛ mu abien, na ɛno nso kyekyɛ yɛ anan, na afei ɛdɔɔso ntɛmntɛm no so. Wɔ nnuruyɛ mu no, wɔfrɛ ɔkwan a nkwammoaa bi fa so kyekyɛ mu abien no mitosis .
Nea taxane nnuru yɛ ne sɛ esiw nkwammoaa mu mpaapaemu kwan.
Fa no sɛ, sɛ nkwammoaa bi mu paapae a, ɛsɛ sɛ wɔkyekyɛ awosu mu nneɛma a ɛwɔ saa nkwammoaa no mu no mu abien pɛpɛɛpɛ na wɔde kɔma nkwammoaa foforo abien no. Nneɛma bi wɔ nkwammoaa no mu a ɛboa ma wɔyɛ adwuma yi, te sɛ nhama nketewa a wɔde kyekyere. Wɔfrɛ eyinom microtubules . Eyinom ne nea ɛtwe afã horow a ehia ma nkwammoaa foforo abien no mu tetew.
Sɛ wɔde taxane aduru no kɔ nipadua no mu a, ɛma nhama a wɔfrɛ no microtubules yi yɛ den a ɛho nhia . Afei wontumi mpopae anaasɛ wontumi mmue yiye. Enti, ɔkwan a wɔfa so kyekyɛ nkwammoaa no mu abien no gyina fã. Sɛ wɔantumi anyɛ saa mpaapaemu yi a, ɔwofo nkwammoaa no wu wɔ bere bi akyi.
Taxane nnuru di kokoram so denam tumi a kokoram nkwammoaa tumi kyekyɛ na enyin a ɛsɛe no so.
Kokoram ahorow bɛn na wɔde taxane nnuru di dwuma ma?
Taxanes yɛ nnuru a ɛho hia yiye a wɔde sa kokoram ahorow pii. Wɔde eyinom bi di dwuma sɛ kokoram ahorow bi ayaresa a edi kan, bere a wɔde afoforo di dwuma ma kokoram ahorow a ɛkɔ mmeae afoforo.
| Kokoram ahorow a wɔde Taxane sa | |
|---|---|
| Kokoram a wɔde dii dwuma titiriw | |
| Kokoram a ɛwɔ awotwaa mu | Nufu mu kokoram |
| Kokoram ahorow afoforo a wɔsa | |
| Kokoram a ɛwɔ akisikuru mu | Awotwaa mu kokoram |
| Yafunu mu kokoram | Ti ne kɔn mu kokoram |
| Prostate kokoram | Ahurututu mu kokoram (Ahurututu mu kokoram a ɛnyɛ nkwammoaa nketenkete) . |
| Awotwaa mu kokoram | Lymphoma a ɛma mogya tu |
Wɔ tebea horow bi mu no, wɔde taxanes ka nnuru afoforo a wɔde sa yare ho ma. Wo duruyɛfo na obesi ayaresa a eye ma wo tebea no ho gyinae.
Ɔkwan bɛn so na wɔde saa ayaresa yi ma? Na dɛn ne nea efi mu ba?
Sɛnea wɔde ayaresa no ma
Wɔde taxanes fa ntini mu (IV) . Wɔnam kankyee (catheter) so ma, a ɛte sɛ nkyene aduru. Saa ayaresa yi betumi agye dɔnhwerew biako anaa nnɔnhwerew pii. Ebia ɛho behia sɛ wonya saa ayaresa yi pɛnkoro dapɛn biara, anaasɛ pɛnkoro wɔ adapɛn kakraa biara mu. Wo duruyɛfo begyina wo tebea no so asi ayaresa nhyehyɛe no ho gyinae.
Nneɛma bɔne a wɔtaa hu
Ɛwom sɛ nnuru a wɔde sa kokoram no de wɔn ani si kokoram nkwammoaa a ɛpaapae ntɛmntɛm so de, nanso ɛtɔ mmere bi a ebetumi aka nkwammoaa a ɛte apɔw na ɛpaapae ntɛmntɛm wɔ yɛn nipadua mu nso. Sɛ nhwɛso no, nneɛma te sɛ yɛn ti nhwi mu nkwammoaa, honam ani nkwammoaa, ne mogya mu nkwammoaa. Eyi nti na nsunsuanso bɔne ba no.
| Nkɛntɛnso a Ɛfa Ho | Nkyerɛkyerɛmu a ɛnyɛ den |
|---|---|
| Neutropenia a ɛma nipadua no yɛ adwuma | Neutrophils, mogya mu nkwammoaa fitaa bi a ɛko tia ɔyare mmoawa a ɛwɔ nipadua no mu no dodow a ɛso tew, na ɛma asiane a ɛwɔ hɔ sɛ obi benya ɔyare mmoawa no yɛ kɛse. |
| Ntini a ɛwɔ akyi no mu yare | Ntini a ɛsɛe wɔ nsa ne anan mu. Eyi betumi ama nsa ne anan ayɛ mmerɛw, ayɛ yaw, anaasɛ ayɛ mmerɛw . |
| Nwi a ɛtɔ | Eyi yɛ ɔhaw a ɛtaa ba, nanso nhwi bɛsan anyin bere a wɔawie ayaresa no. |
| Ɔfe ne akisikuru | Ɛtaa ba wɔ nna a wɔde sa yare no mu. Wɔde nnuru ma de siw eyi so. |
| Ntini ne nkwaa mu yaw | Ebia ɛyaw bɛba nipadua no mu na nkwaa no ayɛ den. |
| Mogya mmoroso sesa | Mogya mmoroso betumi akɔ soro anaasɛ ɛbɛkɔ fam. |
| Mogya mu nkwammoaa a ɛso tew | Mogya mu nkwammoaa kɔkɔɔ a ɛso tew no betumi ama mogya atɔ nipadua no mu na mogya nkwammoaa a ɛso tew (thrombocytopenia) betumi ama mogya atɔ obi. |
Saa nsunsuanso bɔne yi mma obiara so. Afei nso, wotumi di wɔn mu pii so. Ɛho hia yiye sɛ wobɛbɔ wo duruyɛfo anaa ayarehwɛfo amanneɛ wɔ ɔhaw biara a wote nka ho.
So asiane bi wɔ saa ayaresa yi mu?
Taxanes yɛ aduru a etu mpɔn yiye a ama kokoram ayarefo nkwa nna akyɛ. Nanso, te sɛ ayaresa nyinaa no, asiane ahorow bi wɔ hɔ.
Ɛtɔ da bi a, nsunsuanso bɔne a yɛaka ho asɛm wɔ atifi hɔ no betumi ayɛ aniberesɛm. Wɔ nsɛm a ɛtete saa mu no, ebia wo duruyɛfo besi gyinae sɛ ɔbɛsesa wo ayaresa nhyehyɛe anaasɛ obegyae bere tiaa bi.
Ade foforo a ɛho hia ne sɛ bere kɔ so no, kokoram nkwammoaa betumi afi ase ‘ayɛ wɔn su’ aduru yi. Ɛne sɛ, wonya nnuru a ɛko tia nnuru . Afei ebia aduru no nkɛntɛnso so bɛtew. Nanso sɛ ɛba saa a, wo duruyɛfo no bɛdan akɔ akwan horow te sɛ nnuru foforo a wɔaka abom a ɔbɛsɔ ahwɛ anaasɛ ayaresa foforo a ɔbɛkamfo akyerɛ so.
Nkrasɛm a Wɔde Kɔ Fie
- Taxane yɛ nnuru a wɔde sa yare a tumi wom yiye a wonya fi afifide mu a ɛma kokoram nkwammoaa ntumi npaapae mu.
- Eyi sa kokoram ahorow pii yiye, a nufu, awotwaa, ne ahurututu ka ho.
- Nsunsuanso bɔne te sɛ ti nhwi a ɛtɔ, akisikuru, ne nipadua mu yaw betumi aba, nanso wobetumi adi emu dodow no ara ho dwuma.
- Ɛho hia yiye sɛ wobɛka ɔhaw ketewaa biara a wobɛte nka bere a woreyɛ ayaresa no ho asɛm kyerɛ wo duruyɛfo anaa ɔyarehwɛfo .
- Kokoram ayaresa yɛ akwantu. Kae bere nyinaa sɛ ɛnyɛ wo nkutoo na wowɔ akwantu yi mu na wowɔ nnuruyɛfo kuw a wɔn ho akokwaw a wɔbɛboa wo.
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