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Alprostadil Injection for Erectile Dysfunction - Let's Talk About This

MBBS
Medically Reviewed by MBBS ✓ Medically Reviewed
📅 Updated: Jul 14, 2026 • ⏱ 6 min read • Editorial policy
Alprostadil Injection for Erectile Dysfunction - Let's Talk About This
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A health problem that many men have, but are a little hesitant to talk about in society, is difficulty in achieving sexual arousal. In medicine, we call this condition Erectile Dysfunction (ED) . This is a condition that can often be treated and cured. So, one successful treatment for this is the Alprostadil injection. Although this is a bit of a sensitive topic, it is very important to be properly informed about this. So today, we will talk about everything about this Alprostadil injection in a very simple way that you can understand.

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What is this Alprostadil injection?

Simply put, Alprostadil is a medication used to treat erectile dysfunction (ED). It works by dilating the blood vessels that supply blood to the penis, helping to achieve and maintain an erection.

This medicine may come under different brand names such as (Caverject), (Caverject Impulse), and (Edex). This is a prescription medicine. Also, it can be used for other medical conditions. If you have any questions about it, ask your doctor.

Things you need to tell your doctor before using this medicine

Before you begin this treatment, it is extremely important to tell your doctor about your complete health history. You should especially be aware of any of the following conditions:

Your health condition Why is notification important?
Any deformity or unusual shape of the penis Using the vaccine under these conditions can cause complications.
If you have received medical advice to avoid sexual intercourse for other health reasons Sexual activity can be risky due to conditions such as heart disease.
If you have ever had a painful erection (priapism) lasting more than 4 hours This medication increases the risk of the condition recurring.
Heart disease or low blood pressure This medication may affect blood pressure.
Bone marrow cancer such as leukemia, multiple myeloma, or sickle cell disease These conditions increase the risk of priapism.
If you have had a penile implant It may not be appropriate to use the vaccine.
Allergy to Alprostadil or any other medicine, food, or dye This is essential to avoid serious allergic reactions.

How exactly is this vaccine used?

This is the biggest problem for many people. This injection is injected into a specific part of the penis. But don't be afraid. Before you do this yourself at home, your doctor or a trained nurse will clearly teach you how to inject it correctly and safely. It is very important to follow those instructions exactly.

Do not use this medicine in more quantity or more frequently than your doctor tells you to.

Very important: Never throw used needles and syringes in the trash. They can be a danger to others. They should be disposed of in a special container (sharps container). If you don't have one, ask your doctor about it.

This medicine is for men only and is definitely not suitable for use in children.

What to do if the medication dose is increased?

If you think you have taken too much medicine, call the National Poisons Information Centre at the Colombo National Hospital immediately. Or, go to the nearest hospital.Go to the Emergency Department (ETU). Don't take this lightly.

Special points to be considered during use

If the awakening lasts more than 4 hours...

This is the most important thing you need to be aware of during this treatment. If your erection lasts more than 4 hours , or if it is accompanied by severe pain , it is a medical emergency. We call this (Priapism) . At this time , without any hesitation, call your doctor immediately or go to the emergency room (ETU) of a hospital. If not treated quickly, permanent damage to the penis may occur.

Sexually transmitted diseases (STIs)

Using this medicine does not protect you or your partner from HIV infection or other sexually transmitted infections (STIs). Therefore, it is very important to practice safe sex practices (e.g., using condoms).

Conflicts with other drugs

If you are taking medication for high blood pressure, be sure to tell your doctor about it. Also, tell your doctor about any other medications, herbs, vitamins, or supplements you are taking. Also, tell your doctor if you smoke or drink alcohol.

What are the possible side effects?

Like any medicine, this one can cause side effects in some people. Let's break them down into two categories.

Side effect Description
Side effects that require immediate medical attention
Allergic reactions Skin rash, itching, swelling of the lips, tongue, face, difficulty breathing.
Prolonged or painful erection (Priapism) A painful or prolonged erection lasting more than 4 hours.
If the side effects persist, you should tell your doctor.
Problems at the injection site Slight bleeding, bruising, or pain at the injection site.
Changes in blood pressure A feeling of dizziness may occur.

This list does not include all side effects. If you experience anything different, talk to your doctor about it.

How to store the medicine?

It is also very important to store this medicine properly.

  • Keep out of reach of children and pets.
  • Caverject: Store unopened vials at or below 25°C (77°F). Do not freeze. Once the medicine is mixed, follow the instructions on the medicine package insert.
  • Edex: Store unopened vials between 15°C and 30°C (59°F - 86°F). Avoid freezing.
  • Throw away expired medication.
  • Do not put it in checked-in luggage on flights. Also, do not leave it inside a vehicle with the doors closed.

💡 Take-Home Message

  • Alprostadil is a medication for sexual dysfunction that should only be used on the recommendation of a doctor.
  • A doctor or trained nurse will teach you the correct way to use this vaccine. Follow those instructions exactly.
  • If your erection lasts more than 4 hours or becomes painful, it is an emergency. Seek medical advice immediately.
  • It is essential to inform your doctor about all other medications you are taking and any other medical conditions you may have.
  • This medicine does not protect against sexually transmitted diseases. Follow safe methods.
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What to do if the medication dose is increased?

If you think you have taken too much medicine, call the National Poisons Information Centre at the Colombo National Hospital immediately. Or, go to the nearest hospital.Go to the Emergency Department (ETU). Don't take this lightly.

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⚠️ Important: Medical articles and information on Nirogi Lanka are strictly for educational and awareness purposes and do not substitute professional medical advice, diagnosis, or treatment. Always consult a qualified physician for any medical concerns.