Kansɛri fura min bɛ kɛ ni an yɛrɛ farikolo ye wa? Aw ka kan ka fɛn minnu dɔn farikolo tangalanw furakɛli ko la

Ni an ye “kansɛri” daɲɛ mɛn, siran ni jɔrɔ bɛ na an hakili la. O ye ko ye min tɛ kojugu ye. Nka, furakɛli dɔnniya yiriwalen kɔfɛ, kansɛri furakɛli fɛɛrɛw ɲɛnabɔra kosɛbɛ. Bi, n bɛna kuma aw fɛ furakɛli fɛɛrɛ ɲuman dɔ kan min ye tulon Changé kansɛri kɛlɛli la, ka jigiya kura lase mɔgɔ caman ma. O bɛ wele ko Immunothérapie. N’an y’a fɔ cogo nɔgɔman na, sanni an ka kɛnɛma furaw di walasa ka kansɛri kɛlɛ , an bɛ baara kɛ n’an yɛrɛ ka lafasalifɛnw ye walasa k’a kɛlɛ. An k’a lajɛ o bɛ kɛ cogo min na.

O la, Immunothérapie ye mun ye?

Walasa k’o faamu, an ka misali fitinin dɔ ta. Ni faritanabana bɛ aw la , i n’a fɔ bugurijɛ, a bɛ se ka kɛ aw ye faritanabana furaw ta. Pikiriw la, faritanabanakisɛ hakɛ dɔɔni ka dɔgɔn kosɛbɛ. Ni a donna aw fari la, aw farikolo tangalanw bɛ baara daminɛ a kɛlɛli la, nka a tɛ aw bana. Ni aw bɛ dɔ fara a tata hakɛ kan dɔɔni dɔɔni, aw farikolo bɛ dege faritanabanakisɛ la. O kɔrɔ ye ko i farikolo bɛ farikolo tangacogo dɔ sabati a ma.

Immunotherapy ye o ɲɔgɔnna fɛn ye. Kansɛri ye ni an yɛrɛ ka farikolokisɛ dɔ y’a daminɛ ka kɛwale “jugu” kɛ ka bɔ a yɛrɛ la. Jigiya min bɛ farikolo tangalanw furakɛli la, o ye ka an farikolo lafasalitɔn dɛmɛ a ka o “banakisɛ juguw” dɔn ani k’a yɛrɛ dege k’u tiɲɛ. I n’a fɔ ka banakisɛ walima banakisɛ dɔ kɛlɛ min bɛ don an fari la.

Banakisɛfagalanw furakɛli suguya jɔnjɔnw ye jumɛnw ye?

Ɲininikɛlaw ye fɛɛrɛ caman sɔrɔ, an farikolo tangalanw bɛ se ka kansɛribanakisɛw dɔn ani k’u tiɲɛ. An ka suguba dɔw lajɛ.

1. Adoptive T-Cell Immunotherapy (T-cell furakɛli min dege kɛrɛnkɛrɛnnenya la) .

O bɛ iko fanga kɛrɛnkɛrɛnnenw dege. Sɔrɔdasi kunbaba minnu bɛ an farikolo tangacogo la, olu dɔ bɛ wele ko T-cells .

Nin furakɛli in na, dɔgɔtɔrɔw bɛ o T-cell dɔw ta ka bɔ aw ka kuru la. O kɔfɛ, laboratuwari kɔnɔ, u b’a ɲini o T-cell ninnu la jumɛn de bɛ kansɛri kɛlɛ kosɛbɛ. U bɛ “sɔrɔdasi ɲumanw” sugandi, u bɛ u jamu sɛgɛsɛgɛ, k’u barika bonya ka tɛmɛn fɔlɔ kan, ka u bonya ka kɛ miliyɔn caman ye.

A laban na, o “T-cell kɛlɛbolo min fanga ka bon kosɛbɛ” bɛ segin ka don i fari la IV fɛ. Sisan, o farikolokisɛw bɛ taa ɲɛfɛ ka kansɛribanakisɛw ɲini ani ka u tiɲɛ.

Furakɛli minnu ka di kosɛbɛ nin kulu in kɔnɔ, olu dɔ ye CAR T-cell furakɛli ye . A bɛ kɛ denmisɛnw ni balikuw ka jolidɛsɛbanatɔw ni kansɛri suguya caman na, i n’a fɔ sɔgɔsɔgɔninjɛ, minnu ma furakɛli wɛrɛw jaabi.

2. Sɛgɛsɛgɛlikɛyɔrɔw balilanw

An farikolo tangacogo fana bɛ ni “frein” ye. Olu bɛ wele ko sɛgɛsɛgɛlikɛyɔrɔw. O freinw bɛ yen walasa k’an farikolo tangalanw bali ka bin an yɛrɛ ka farikolokisɛ kɛnɛmanw kan kun tɛ.

Nka kansɛribana namaratɔw bɛ nafa sɔrɔ o freinw kɛcogo la. U bɛ farikolojɔlifɛnw dilan u sanfɛ minnu bɛ o sɛgɛsɛgɛlikɛyɔrɔ ninnu baara, ka taamasiyɛn ci lafasalitɔn ma, k’a fɔ ko “Ne ye aw ta dɔ ye, aw kana bin ne kan.” A bɛ iko son dɔ bɛ polisiw ka fini don.

Checkpoint inhibitor furaw bɛ baara kɛ ni nin "frein" in bɔli ye min bɛ kansɛribana banakisɛw minɛ u nɔ na. O b’a to an ka T-cellw bɛ kansɛri dɔn iko jugu ani ka bin a kan.

Nin furakɛli fɛɛrɛ in bɛ kɛ ka ɲɛ sisan kansɛri suguya caman na, i n’a fɔ fogonfogon, sin, sugunɛ, ani fari kansɛri (melanoma).

3. Banakisɛfagalanw (Monoclonal Anticorps).

Olu ye farikolo tangalanw ye, minnu dilannen don kɛrɛnkɛrɛnnenya la laboratuwari kɔnɔ. U bɛ i n'a fɔ "missiles" minnu bɛ se ka kansɛribanakisɛw ɲini ani k'u minɛ.

An farikolo tangalanw tɛ se ka kansɛribana banakisɛw dɔn tuma bɛɛ ko u ye “juguw” ye. Banakisɛfagalan kelen-kelenw b’a dɛmɛ k’o kɛ. O banakisɛfagalanw bɛ nɔrɔ kansɛribanakisɛw sanfɛla la. O kɔfɛ, a bɛ i n’a fɔ darapo bɛ pan o selilɛri sanfɛ, o bɛ a to a ka nɔgɔn farikolo tangalanw ma k’a ye. A bɛ iko i b'a fɔ ko: "Jugu filɛ nin ye." O kɔ, T-cellw bɛ se k’o kansɛribanaw tiɲɛ nɔgɔya la.

Kansɛribana furaw ( chimiothérapie ) walima fɛn minnu bɛ kɛ ni radiyowaati ye, olu bɛ sɔrɔ farikolo tangalan kelen-kelen dɔw la. O kɔfɛ, o banakisɛfagalan bɛ fura in ta ka taa kansɛribanakisɛ la k’a lase.

4. Kansɛri bolociw

Ninnu bɛ i n’a fɔ boloci basigilenw. A suguba fla bɛ yen:

• Banakisɛfagalanw : Ninnu ye bolociw ye minnu bɛ mɔgɔ tanga banakisɛw ma minnu bɛ se ka kansɛri bila mɔgɔ la. A misali ɲuman ye HPV (Human Papillomavirus) boloci ye. Nin HPV banakisɛ in bɛ se ka kɔnɔbara basigilen kansɛri bila mɔgɔ la ka fara kansɛri suguya caman wɛrɛw kan. VPH boloci sɔrɔli bɛ se ka dɔ bɔ o farati la kosɛbɛ. A nafa ka bon kosɛbɛ ka kuma dɔgɔtɔrɔ fɛ o ko la ani ka kunnafoni wɛrɛw sɔrɔ.
• Furakɛli bolociw : Ninnu dabɔra ka farikolo tangalanw dege walasa ka kansɛri dɔ kɛlɛ min bɛ farikolo la kaban.

Banakisɛfagalanw ka siniɲɛsigi ye mun ye?

Banakisɛfagalanw furakɛli ye baara ye min bɛ ka yiriwa teliya la hali bi, bawo dɔnnikɛlaw b’a ɲini tuma bɛɛ k’a faamu ka ɲɛ an farikolo tangacogo bɛ kansɛri kɛlɛ cogo min na.

Ka fara o kan, ɲininiw bɛ ka kɛ walasa k’a dɔn ni farikolo tangalanw bɛ se ka kɛ ka fara furakɛli wɛrɛw kan, i n’a fɔ chimiothérapie, walasa ka furakɛli kɛcogo ɲɛ. Tuma dɔw la, farikolo tangalan suguya fila bɛ kɛ ɲɔgɔn fɛ.

Nka ɲininkaliba dɔ bɛ yen hali bi min jaabi ma sɔrɔ. O kɔrɔ ye ko nin furakɛli in, i n’a fɔ furakɛli tɔw, a bɛ baara kɛ ka ɲɛ banabagatɔ dɔw la k’a sɔrɔ a tɛ baara kɛ kosɛbɛ dɔw la. Sɛgɛsɛgɛli bɛ sen na hali bi walasa ka o kunw sɔrɔ.

Banakisɛfagalanw furakɛli, kansɛri furakɛli, kansɛri furakɛli sinhala , T-cells, checkpoint inhibiteurs, monoclonal anticorps, CAR T-cell furakɛli, kansɛri, Sri Lanka