Acromegaly: Ðe wò abɔ kple afɔwo lolo le mɔ si mebɔ o nua? Mina míaƒo nu!

Ède dzesii kpɔ be wò abɔwo, afɔwo, alo mo ƒe nɔnɔme le tɔtrɔma? Ðewohĩ asigɛ si nèdona la sena le eɖokui me zi geɖe be ebla ɖe ye ŋu, alo wò afɔkpa ƒe lolome trɔa? Menye nusiwo dzɔna le vome koe esiawo nye o, woate ŋu anye dɔléle aɖe si mebɔ o gake ate ŋu anye nu sesẽ si woyɔna be acromegaly . Mègatsi dzi o, míaƒo nu tso esia ŋu tsitotsito eye míaƒo nu tso eŋu ko egbea.

Nukae nye Acromegaly? Kpuie ko la,...

Acromegaly nye dɔléle si atike aɖe si woyɔna be Growth Hormone (GH) ƒe agbɔsɔsɔ fũ le wò ŋutilã me hena vɛ. Zi geɖe la, pituitary gland , si nye lãkusi si lolo abe pea ene si le míaƒe ahɔhɔ̃a ƒe gɔme lae wɔa tsitsiŋusẽ sia (GH). Gake le acromegaly me la, lãmetsi sia dzɔna wògbɔa eme le dɔdzẽ aɖe si le lãkusi si me ʋu sina tona me alo le ŋutilãa ƒe akpa bubu ta.

Ènya be lãkusi si woyɔna be pituitary gland nye lãkusi sue aɖe gake wòle vevie ŋutɔa. Eɖea lãmetsi enyi doa goe, eye wo dometɔ ɖekae nye tsitsi ƒe lãmetsi (GH).

Nukae nye tsitsi ƒe lãmetsi (GH) na mí?

Tsitsi ƒe Lãmetsiŋusẽ, si wogayɔna be Amegbetɔ ƒe Tsitsi ƒe Lãmetsiŋusẽ (hGH) alo Somatotropin , nye dzɔdzɔme lãmetsi. Ele vevie na míaƒe ŋutilã ƒe akpa vovovowo ƒe tsitsi kple kɔkɔme le ɖevime. Gake ne míele tsitsim la, ne míaƒe ƒuwo ƒe epiphyses tu vɔ la, míaƒe ŋutilã gakpɔtɔ hiã GH sia. Ènya nusitae? Ekpena ɖe mía ŋu be míaƒe ƒuwo, ƒunukpeƒewo, kple ŋutinuwo ƒe wɔwɔme nanɔ lãmesẽ me, eye wòkpena ɖe lãmenugbagbeviwo ƒe dɔwɔwɔ ŋu, vevietɔ be míaƒe ʋumesukli ƒe agbɔsɔsɔ nɔa agbɔsɔsɔ si sɔ me.

Eyata ne ŋutilãa ƒe tsitsiŋusẽ (GH) dzi ɖe edzi akpa le tsitsi megbe la, kuxiwo abe ƒu ƒe dɔmawɔmawɔ nyuie, ŋutinuwo ƒe lolome, kple sukli ƒe dzidziɖedzi le ʋu me (suklidɔ) ate ŋu ado mo ɖa.

Vovototo kae le Acromegaly kple Gigantism dome?

Tsitsi ƒe lãmetsi (GH) ƒe dzidziɖedzi gbɔe wo ame evea siaa tsona. Gake vovototoa le amesiwo ŋu nɔnɔmea gblẽa nu le la me. Ame tsitsiwo va xɔa acromegaly. Ðeviwo va zua gãnyenye .

Ne tsitsi ƒe lãmetsi (GH) ƒe agbɔsɔsɔ dzi ɖe edzi le ɖeviwo me hafi tsitsi ƒe agbalẽvi siwo le woƒe ƒuwo me la tu (i.e., hafi woƒe sɔhɛmenɔɣi wu enu) la, woatsi le mɔ si mesɔ o nu. Woyɔa esia be gãnyenye. Ƒã wu acromegaly. Ðɔkta aɖewo hã yɔnɛ be "ɖeviwo ƒe acromegaly."

Gake ne wò tsitsi ƒe lãmetsi (GH) ƒe agbɔsɔsɔ dzi ɖe edzi le wò tsitsi ƒe agbawo tutu vɔ megbe la, màtsi kɔkɔ wu o. Gake lãmetsiŋusẽ ma si sɔ gbɔ ate ŋu akpɔ ŋusẽ ɖe wò ƒuwo ƒe nɔnɔme, wò ŋutinuwo ƒe lolome, kple lãmesẽnya bubuwo dzi. Woyɔa nɔnɔme ma be acromegaly.

Amekae ate ŋu axɔ acromegaly wu?

Ate ŋu adze egɔme le ƒe ɖesiaɖe me le sɔhɛmenɔɣi megbe. Gake zi geɖe la, ɖɔktawo kpɔa dɔlélea le amesiwo xɔ tso ƒe 40 va ɖo ƒe 50, si fia be le ƒe titina.

Aleke gbegbee esia bɔe?

Le nyateƒe me la, acromegaly nye dɔléle si mebɔ o . Ame siwo ade 31 le ame 100,000 dome koe wokpɔ dɔléle sia le. Eyata mègavɔ̃ madzemadzee o, gake ele vevie be nànya dzesiawo.

Aleke acromegaly kpɔa ŋusẽ ɖe nye ŋutilã dzii?

Ne ame tsitsi aɖe xɔ acromegaly, si fia be ne tsitsiŋusẽ (GH) dzi ɖe edzi la, ƒuwo, ƒunukpeƒewo, ŋutilã ƒe ŋutinuwo, kple lãmenugbagbevi bubuwo tea lolo ɖe edzi. Tɔtrɔ siwo dze ƒã le dzedzeme ŋu . Le kpɔɖeŋu me:

• Asiwo kple afɔwo ƒe lolome.
• To, nuyi, kple ŋɔti ƒe lolome.
• Aɖu si do go, ŋgonu si lolo.

Tsitsi ƒe lãmetsi (GH) naa dzesi míaƒe aklã be wòawɔ lãmetsi bubu si woyɔna be Insulin-like Growth Factor 1 (IGF-1) . Lãmetsi sia si woyɔna be IGF-1 kpena ɖe míaƒe ƒuwo kple ŋutilã ƒe lãkusiwo ŋu ŋutɔŋutɔ be woatsi, eye wòkpɔa ŋusẽ ɖe alesi míaƒe ŋutilã kpɔa ʋumesukli (glucose) kple ami (lipids) dzi hã dzi. Eyata ne GH ƒe agbɔsɔsɔ dzi ɖe edzi la, IGF-1 ƒe agbɔsɔsɔ hã dzina ɖe edzi. Esia ate ŋu ahe nɔnɔmewo abe Suklidɔ Ƒomevi 2 , Ʋusɔgbɔdɔ (Ʋusɔgbɔdɔ) , kple Dzidɔ ene vɛ.

Bu eŋu kpɔ ko, abe alesi pɔmpi si wogblẽ ɖi wònɔa sisim ɣeyiɣi didi akpa gblẽa tsi ene la, lãmetsi siawo, ne wosɔ gbɔ akpa la, wokpɔa ŋusẽ vovovowo ɖe ŋutilãa dzi.

Nukawoe hea acromegaly vɛ?

Nusi gbɔ acromegaly tsona wue nye dɔdzẽ si le lãkusi me. Woyɔa esia be pituitary adenoma . Dɔdzẽ sia nana ƒunukpeƒetetedɔa ɖea tsitsi ƒe lãmetsi (GH) si sɔ gbɔ akpa la doa goe.

Nya geɖe tso Pituitary Adenoma ŋu vie...

Zi geɖe la, pituitary adenomas siawo mewɔa dɔ nyuie o. Eyae nye be womenye kansa o. Dɔdzẽ siwo hea acromegaly vɛ ƒe akpa gãtɔ tsina blewu ŋutɔ. Eyata, ɖewohĩ màde dzesi GH si sɔ gbɔ sia ƒe dzesi aɖeke o ƒe geɖe.

Le alesi dɔdzẽa loloe kple afisi wòle nu la, ate ŋu aƒoe ɖe lãkusia ƒe akpa bubuwo eye wòakpɔ ŋusẽ ɖe lãmetsiŋusẽ bubu siwo lãkusia wɔna dzi. Ne dɔdzẽa lolo la, ate ŋu aƒo ahɔhɔ̃a ƒe akpa siwo te ɖe eŋu hã, si ana ta naɖu ame eye wòana nu nakpɔ kuxiwo .

Nukae nye Acromegaly ƒe dzesiwo?

Ne acromegaly dze ame tsitsi aɖe dzi la, egblẽa nu le ŋutilãa ƒe ƒuwo kple lãkusiwo ŋu, si wɔnɛ be wotsina le mɔ si mesɔ o nu. Esia ate ŋu ahe dzesi siwo gbɔna vɛ:

• Asi alo afɔ siwo lolo: Ðewohĩ wò asigɛwo adze ƒoƒo gɔme, eye wò afɔkpa ƒe lolome, vevietɔ eƒe kekeme, adzi ɖe edzi.
• Tɔtrɔ le mo ƒe nɔnɔme me: Aɖu ƒe akpa si do ɖe gota alo eƒe lolome kple/alo ŋgonu.
• Nuyiwo, ŋɔti, kple/alo aɖe ƒe lolome.
• Fifia fũ alo ŋutigbalẽ si me ami le.
• Gbe ƒe goglome kple gbeɖiɖi ƒe ɖiɖi.

Dzesi bubuwo:

• Taɖuame
• Ƒunukpeƒewo ƒe vevesese
• Nukpɔkpɔ trɔna
• Ŋutilã ƒe dzesi suesuesuewo ƒe dzidziɖedzi
• Asiwo ƒe ʋuʋu
• Alɔ̃dɔdɔ ƒe gbɔgbɔtsixetsixe (alɔ̃dɔdɔ ƒe gbɔgbɔtsixetsixe) .
• Carpal tunnel syndrome alo aklã ƒe kuxiwo.

Zi geɖe la, acromegaly ƒe dzesiwo dzena blewu ŋutɔ , ɣeaɖewoɣi le ƒe geɖe megbe. Eyata ate ŋu asesẽ be woakpɔ wo adze sii le gɔmedzedzea me. Ðeko ame aɖewo dea dzesii be yewoƒe asiwo lolo wu ne asigɛ si wodona la va le sesẽm alo woƒe afɔkpa ƒe lolome trɔ.

Bu eŋu kpɔ, ame aɖe li si ŋkɔe nye Nilanthi. Ese le eɖokui me be yeƒe srɔ̃ɖesigɛa le sesẽm hena ɣeyiɣi aɖe fifia. Eƒe afɔkpawo mesẽ abe tsã ene o, wole sesẽm vie. Esusu be ɖeko yelolo ɖe edzi teti koe nye ema. Gake le ɣeyiɣi ma ke me la, exɔlɔ̃wo le gbɔgblɔm be eƒe mo to vovo vie wu tsã, eye eƒe asike lolo vie. Esiawoe nye nu suesuesue siwo wodea dzesii gbã.

Ne dzesi siawo le ŋuwò la, ele vevie ŋutɔ be nàƒo nu kple ɖɔkta.

Aleke wokpɔa Acromegaly ƒe dɔlélea?

Esi wònye be dzesiawo dzena blewu ŋutɔ ta la, le ƒe geɖe megbe la, ate ŋu asesẽ vie be woakpɔ dɔlélea.

Wò ɖɔkta ate ŋu aɖo wò ɖe lãmenugbagbeviwo ŋuti nunyala , si nye ɖɔkta si bi ɖe dɔléle siwo do ƒome kple lãmetsiŋusẽwo me. Anɔ te ɖe wò atikewɔwɔ ŋutinya, dɔdamɔnu dodokpɔ, kple dodokpɔ tɔxɛwo (abe ʋudodokpɔ kple nɔnɔmetatawo dodokpɔ ene) dzi akpɔ dɔlélea.

Nukawoe nye dodokpɔ siwo wowɔna tsɔ dia dɔlélea?

Ne wokpɔe be acromegaly le ŋuwò la, wò ɖɔkta ate ŋu aɖe gbe be woagawɔ dodokpɔ bubuwo atsɔ akpɔe ɖa be dɔlélea gblẽ nu le wò ŋutilã ƒe akpa bubuwo hã. Esiawo ate ŋu anye:

• Echocardiogram dodokpɔ aɖe si wowɔna tsɔ léa ŋku ɖe dzitodzito me kuxiwo ŋu.
• Alɔ̃dɔdɔ ŋuti nusɔsrɔ̃ dodokpɔwo be woakpɔe ɖa be gbɔgbɔtsixe tsia ƒowò le alɔ̃dɔdɔ me hã.
• Dɔgbomekpɔkpɔ be woatsɔ akpɔ dɔgboa ƒe lãmesẽ.
• Kpɔ ƒuwo ƒe lãmesẽ ɖa to X-ray alo DEXA scan dzi .

Aleke wowɔa atike na Acromegaly?

Atikewɔwɔ vovovowo li na acromegaly. Le wò dzesiwo kple nɔnɔme si me nèle nu la, wò ɖɔkta aɖo atikewɔmɔnu si sɔ na wò.

Dɔdamɔnu siwo wozãna wue nye:

• Amekoko
• Atikewo zazã
• Kekeli ƒe atikewɔwɔ

Amekoko na Acromegaly

Le go geɖe me la, amekoko ate ŋu aɖe acromegaly ƒe dzesiwo dzi akpɔtɔ ŋutɔ alo ada wo keŋkeŋ. Zi geɖe la, amekolawo zãa mɔnu aɖe si woyɔna be transsphenoidal surgery , si bia be woawɔ dɔa to ŋɔti me kple to sphenoid sinus (si nye teƒe si me do le le ŋɔti ƒe mɔwo megbe, le ahɔhɔ̃a te) me.

Amekokoa ŋuti nyatakakawo nɔ te ɖe dɔdzẽa ƒe lolome kple afisi wòle dzi. Taɖodzinu vevitɔ si le amekoko ŋue nye be woaɖe dɔdzẽ si le tsitsi ƒe lãmetsi (GH) si sɔ gbɔ wu la hem vɛ la ɖa keŋkeŋ. Ne amekolaa te ŋu ɖe dɔdzẽa ƒe akpa gã aɖe ɖa la, ɖewohĩ mahiã be woawɔ atike bubu aɖeke na wò o. Gake ne woɖe dɔdzẽa ƒe akpa aɖe ko la, ɖewohĩ ahiã be nàzã atike alo keklẽŋusẽdɔdamɔnu be nàɖu dzesiawo dzi eye nàɖe tsitsiŋusẽ (GH) ƒe wɔwɔme dzi akpɔtɔ.

Atike Siwo Wozãna Na Acromegaly

Wò ɖɔkta ate ŋu aŋlɔ atike ɖeka alo atike vovovowo na wò. Atikeawo wɔa dɔ le mɔ vovovowo nu be woana wò ŋutilã ƒe tsitsiŋusẽ (GH) ƒe agbɔsɔsɔ nasɔ ɖe ɖoɖo nu eye woaɖe dzesiawo dzi akpɔtɔ. Le go aɖewo me la, wonaa atike la vaseɖe esime dɔdzẽa natsi, ale be amekola ate ŋu aɖee ɖa dedie. Ðewohĩ ahiã be ame bubuwo nano atike ɣeyiɣi didi be woatsɔ akpɔ tsitsimeŋusẽ (GH) ƒe agbɔsɔsɔ kple dzesiwo dzi.

Ðe woate ŋu ada acromegaly keŋkeŋa?

Woate ŋu ada acromegaly ɣeaɖewoɣi, gake menye ɣesiaɣie o. Ne wowɔ dɔ na ƒunukpeƒetetedɔ si hea acromegaly vɛ la, eƒe dɔyɔyɔ anɔ abe 85% ene na dɔdzẽ suewo . Le dɔdzẽ gãwo gome la, ele 40% va ɖo 50% dome.

Atikewo mate ŋu ada acromegaly keŋkeŋ o, gake woate ŋu ana woadae ɣeyiɣi didi si me afɔku mele o .

Ðe woate ŋu axe mɔ ɖe acromegaly nua?

Nublanuitɔe la, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe acromegaly nu o. Dzɔdzɔmeŋutinunyalawo meka ɖe nusi hea pituitary tumors siwo hea acromegaly vɛ dzi haɖe o. Ke hã, woxɔe se be domenyiŋusẽfianu aɖewo ate ŋu awɔ akpa aɖe.

Nukae nye acromegaly ƒe ŋgɔdonya?

Esia ƒe mɔkpɔkpɔ nɔ te ɖe dɔlélea ƒe sesẽme kple alesi woate ŋu akpɔ dzesiawo dzi nyuie to atikewɔwɔ me dzi. Ame geɖe kpɔnɛ be dzesiwo dzi ɖena kpɔtɔna ŋutɔ le atikewɔwɔ vɔ megbe.

Ne womewɔ atike na acromegaly o la, ate ŋu atrɔ wò dzedzeme kple wò ƒuwo ƒe nɔnɔme vevie. Dzesi siawo ate ŋu akpɔ ŋusẽ gã aɖe ɖe bubudede ɖokuiwò ŋu kple wò agbenɔnɔ ƒe nyonyome dzi. Kpekpeɖeŋunahawo kpena ɖe ame aɖewo ŋu wonɔa te ɖe acromegaly ƒe kuxiwo nu.

Acromegaly ate ŋu ahe lãmesẽkuxiwo hã vɛ, abe dzidɔ alo suklidɔ ƒomevi evelia ene, si ate ŋu aɖe agbenɔnɔ ƒe nyonyome dzi akpɔtɔ eye wòana ame ƒe agbenɔƒe nadidi ɖe edzi. Eyata ele vevie be nàyi ɖɔkta gbɔ ne dzesiwo le ŋuwò eye ne wokpɔe be dɔlélea le ŋuwò la, nàwɔ ɖe atikewɔwɔ ƒe ɖoɖo aɖe dzi nyuie.

Kuxi kawoe ate ŋu ado mo ɖa ne womewɔ atike nɛ o?

Ne womewɔ atike na acromegaly o la, ate ŋu ahe kuxiwo abe:

• Suklidɔ ƒomevi 2 lia
• Ʋusɔgbɔdɔ (Hypertension) .
• Dzidɔ
• Dzi ƒe lãmekawo ƒe dɔléle (Cardiomyopathy) .
• Ƒunukpeƒetetedɔ
• Colon polyps - Esiawo ateŋu azu kansa ne womewɔ atike na wo o.
• Lãmenugbagbeviwo ƒe kpododonu

Nukae nye ame si ŋu acromegaly le ƒe agbenɔƒe?

Esia nɔ te ɖe alesi dɔlélea nu sẽe kple ne lãmesẽkuxi bubuwo li dzi, eye zi geɖe la, acromegaly si womeda dɔ na o gbɔe wòtsona.

Ne womekpɔ wò tsitsi ƒe lãmetsi (GH) ƒe agbɔsɔsɔ dzi nyuie o eye nɔnɔme bubuwo abe dzidɔ kple suklidɔ ene le ŋuwò la, woate ŋu aɖe wò agbenɔƒe dzi akpɔtɔ abe ƒe 10 ene.

Gake ne acromegaly le ŋuwò, woda dɔ na wò nyuie, eye tsitsime lãmetsiŋusẽ (GH) kple IGF-1 ƒe agbɔsɔsɔme sɔ la, ke anɔ eme be ànɔ agbe si sɔ.

Ɣekaɣie wòle be makpɔ ɖɔkta le acromegaly ŋu?

Ne acromegaly ƒe dzesiwo le ŋuwò la, ele vevie ŋutɔ be nàƒo nu kple ɖɔkta.

Ne wokpɔe be acromegaly le ŋuwò la, ahiã be nàyi ɖɔkta gbɔ edziedzi be nàkpɔ egbɔ be wò atikewɔwɔa le dɔ wɔm nyuie.

Acromegaly nye dɔléle si mebɔ o gake wòsẽ ŋutɔ. Nya nyuiae nye be woate ŋu atsɔ amekoko, atikewo, kple/alo keklẽŋusẽdɔdamɔnu adae. Ne ède dzesii be wò asiwo, afɔwo, kple/alo mo ƒe dzedzeme le lolom ɖe edzi la, ke ƒo nu kple wò ɖɔkta. Ate ŋu awɔ dodokpɔ bɔbɔe ʋɛ aɖewo akpɔe ɖa be wò tsitsiŋusẽ (GH) ƒe agbɔsɔsɔ gbɔe wò dzesiawo tso hã.

Mlɔeba la, gbedasi si woatsɔ ayi aƒemee

• Acromegaly nye dɔléle si mebɔ o le ame tsitsiwo me si tsoa tsitsi ƒe lãmetsi (GH) ƒe dzidziɖedzi gbɔ.
• Dzesiawo ate ŋu anye abɔwo kple mo ƒe vuvu, fifia fũ, kple gbe ƒe tɔtrɔ . Esiawo ate ŋu adze vivivi, eyata ɖewohĩ màde dzesi wo o.
• Nusi koŋ gbɔ esia tsonae nye dɔdzẽ, si zi geɖe menye kansa o, si dona le lãkusi si me ʋu sina tona me.
• Ne wokpɔe kaba eye wodae la, ate ŋu axe mɔ ɖe kuxi geɖe nu eye wòana agbenɔnɔ nanyo ɖe edzi.
• Ne dzesi siawo le ŋuwò la, mègahe ɖe megbe le atikewɔlawo ƒe aɖaŋuɖoɖo didi me o. Emae nye nusi me nunya le wu.

Taflatse ɖo ŋku edzi be nyatakaka siawo nye nyatakakawo nana ko. Mele be woazãe atsɔ aɖo atikewɔlawo ƒe aɖaŋuɖoɖo teƒe gbeɖe o. Ne lãmesẽkuxi aɖe le ŋuwò la, taflatse yi atikewɔla bibi aɖe gbɔ.

` Acromegaly, Tsitsi ƒe Lãmetsiŋusẽ, Pituitary Gland, Gigantism, IGF-1, Lãmetsiŋusẽ ƒe dɔléle, Endocrine