Acute Fatty Liver of Pregnancy (AFLP): Esia nye nya vevi aɖe, mina míanɔ ŋudzɔ!

Ènya be ɣeaɖewoɣi la, lãmesẽkuxi siwo mèle mɔ kpɔm na o ate ŋu ado mo ɖa le fufɔɣia? Egbea míele nu ƒom tso nɔnɔme aɖe si ate ŋu anye nu sesẽ si ŋu wòle be míanya nu tsoe, nenye be enye nusi womele mɔ kpɔm na o vie gɔ̃ hã. Togbɔ be esia medzɔna ɖe ame akpa gãtɔ dzi o hã la, ne edzɔ la, ehiã be woawɔ atike nɛ enumake.

Nukae nye aklãdɔ sia si woyɔna be ami ƒe dɔléle (AFLP) le fufɔɣi?

Kpuie ko la, Acute Fatty Liver of Pregnancy (AFLP) nye dɔléle si mebɔ o gake wòsẽa ŋu ŋutɔ. Esiae nye esime ami yɔ wò aklã fũ akpa le fufɔɣi. Esia ate ŋu ahe aklã ƒe dɔmawɔmawɔ nyuie kple kuxi bubu siwo ate ŋu ade ame ƒe agbe afɔku me vɛ. Le nyateƒe me la, wobua eŋu be enye atikewɔwɔ kpata . Ne edzɔ alea la, nu nyuitɔ si nàwɔe nye be nàdzi vidzĩa kaba ale si nàte ŋui.

Aleke gbegbee AFLP bɔe?

Mègatsi dzi o, esia mebɔ boo o. Le nyateƒe me la, nɔnɔme sia si woyɔna be AFLP mebɔ kura o. Wogblɔ be fufɔfɔ 10,000 va ɖo 20,000 ɖesiaɖe dometɔ ɖeka koe wòdzena le ƒe ɖeka me. Eyata menye nusi nèkpɔna zi geɖe ŋutɔe wònye o.

Nukae nye AFLP ƒe dzesiwo? (Nɔ ŋudzɔ le esiawo ŋu)

Zi geɖe la, AFLP dzea egɔme le fufɔfɔ ƒe ɣleti etɔ̃lia ƒe nuwuwu – anɔ abe kwasiɖa 36 ene – eye zi geɖe la, wokpɔnɛ. Gake ate ŋu adzɔ ɣeaɖewoɣi do ŋgɔ, alo vaseɖe esime woadzi vidzĩa gɔ̃ hã.

Dzesi aɖewo li siwo wokpɔna zi geɖe le nɔnɔme sia me:

• Aɖuɖɔtoe kple ʋuʋudedi: Togbɔ be esia adze nusi sɔ le fufɔɣi hã la, ate ŋu anye AFLP ƒe dzesi ɣeaɖewoɣi.
• Ƒodo ƒe vevesese: Vevesese sia dzɔna vevietɔ le ƒodoa ƒe ɖusime ƒe akpa si le etame.
• Ðeɖiteameŋu sesẽ: Menye ɖeɖiteameŋu koe o, ke boŋ ɖeɖiteameŋu si gbɔ eme ƒe seselelãme.
• Seselelãme be ame ƒe ŋutilã me mekɔ o: Seselelãme be yeƒe ŋutilã me mekɔ o, abe ɖe dɔléle aɖe le fu ɖem na wò ene.
• Nuɖuɖumadzroame: Nuɖuɖu ƒe dzodzro ɖesiaɖe si meganɔa ame me o.
• Tsikɔwuame si gbɔ eme: Tsi agbɔsɔsɔme ka kee nèno o, egasena le ɖokuiwò me kokoko be mesɔ gbɔ o.
• Jaundice: Wò ŋutigbalẽ kple wò ŋku ƒe ɣiwo trɔna zua ɣie. Esia nye dzesi si dze ƒã ŋutɔ.
• Tɔtɔ alo susu ƒe ŋutete manɔamesi: Esesẽna be wò susu nanɔ nu ŋu, sese le eɖokui me be yemele ɖeke me o.

Ðo ŋku edzi be AFLP ƒe dzesiwo ate ŋu asɔ kple atikewɔwɔ me nɔnɔme bubuwo tɔ. Eyata ele vevie be nàƒo nu kple wò ɖɔkta tso dzesi ɖesiaɖe si mebɔ o si nàkpɔ le fufɔɣi ŋu. AFLP nye atikewɔwɔ kpata si hiã be woawɔ atike nɛ enumake.

Nukatae AFLP sia dzɔna? Nuka tae?

Numekulawo menya nusi tututu hea AFLP vɛ haɖe o. Dɔ vevi siwo míaƒe aklã wɔna dometɔ ɖekae nye be wòagbã ami siwo me ami le. Le AFLP me la, kuxi aɖe le aklã ƒe ŋutete be wòagbã ami siawo me, si wɔnɛ be ami si sɔ gbɔ wu la ƒoa ƒu ɖe aklãa me. Emegbe ami sia gena ɖe aklãa me, si doa kplamatse aklãa ƒe dɔwɔwɔ nyuie. Esia ate ŋu ade ame ƒe agbe afɔku me ne womewɔ atike nɛ o.

Ðe kadodo aɖe le domenyiŋusẽfianu domea? (LCHAD ƒe anyimanɔmanɔ) .

Numekuku aɖewo ɖee fia be AFLP ate ŋu akpɔ ŋusẽ ɖe domenyiŋusẽfianu dzi . Eyae nye be ate ŋu atso enzyme aɖe ƒe anyimanɔmanɔ si woyɔna be long-chain 3-hydroxyacyl-CoA dehydrogenase (LCHAD) ƒe anyimanɔmanɔ gbɔ .

(LCHAD) ƒe anyimanɔmanɔ sia nye dɔléle si mebɔ kura o, (autosomal recessive) . Kpuie ko la, hafi vidzĩ nanyi esia ƒe dome la, ele be dzila evea siaa naxɔ domenyiŋusẽfianu si sɔ na esia. Vidzĩ si ŋu (LCHAD) ƒe dɔmawɔmawɔ nyuie mate ŋu atrɔ ami siwo le lãme na ame nyuie o. Emegbe ami siawo gena ɖe vidadaa ƒe ʋu me to vidzidɔa me. Esia ate ŋu ana ami naƒo ƒu ɖe vidadaa ƒe aklã me. Bu alesi tɔtrɔ si va le vidzĩa ƒe ŋutilã ƒe lãmenugbagbeviwo ƒe dɔwɔwɔ me kpɔa ŋusẽ ɖe vidadaa dzii ŋu kpɔ!

Nukawoe nye afɔku siwo ate ŋu ana woaxɔ AFLP?

Míenya azɔ be nɔnɔme sia si woyɔna be AFLP ate ŋu atso domenyiŋusẽfianu gbɔ. Ema fia be woate ŋu anyie ƒe dome tso dzilawo gbɔ. Tsɔ kpe ɖe eŋu la, afɔku bubu geɖewo li:

• Ne esiae nye wò fu gbãtɔ.
• Ne èle mɔ kpɔm na venɔvi alo esi wu nenema.
• Ne èle mɔ kpɔm na ŋutsuvi.
• Ne suklidɔ le ŋuwò.
• Ne fufɔfɔ ƒe aklã me ʋumenugbagbeviɣidɔ le ŋuwò.
• Ne preeclampsia le ŋuwò.
• Ne èlolo akpa.

Gake, togbɔ be afɔku siawo katã li hã la, wò ɖɔkta mate ŋu agblɔe ɖi nenye be àxɔ AFLP o. Eye menye nane si nàte ŋu agblɔe ɖi ahaxe mɔ ɖe enu o. Emae na wòtsi dzi vie wu.

Nukawoe nye kuxi siwo ate ŋu ado tso AFLP me? (Esia ate ŋu anye afɔku)

Aklãdɔléle sesẽ (AFLP) le fufɔɣi ate ŋu awu ame . Mia kple viwòa miele afɔku me le kuxi vovovowo me. Wo dometɔ aɖewoe nye:

• Aklã ƒe dɔmawɔmawɔ nyuie.
• Ayiku ƒe dɔmawɔmawɔ nyuie.
• Aklã ƒe dɔmawɔmawɔ nyuie.
• Dɔdzedze.
• Ʋu si dona le lãme na ame.

Edoa vɔvɔ̃ na ame be woase nya siawo, alo? Esia tae wòle vevie be nànya nɔnɔme sia ɖo.

Aleke woawɔ ade dzesi AFLP ƒe nɔnɔme?

Esi wònye be AFLP ate ŋu ana ŋutinuwo nawɔ dɔ nyuie o ta la, .Ele vevie be woanya dɔlélea kaba eye woadze edada gɔme kaba. Nusi woate ŋu akpɔ nyuie wue nye aklã me lãmenugbagbeviwo ɖeɖe . Afi siae wò ɖɔkta doa wò aklã ƒe lãkusiwo kpɔna le nusuekpɔmɔ̃ me. Gake menye ɣesiaɣie esia wɔwɔ le dedie le fufɔɣi o. Eyata zi geɖe la, wò ɖɔkta ate ŋu anɔ te ɖe wò dzesiwo kple lãmesẽ ŋutinya dzi anya AFLP.

Nukae ʋudodokpɔwo dia?

Wò ɖɔkta aɖe gbe be woado ʋu kpɔ be AFLP hã le eme. Ɣeaɖewoɣi la , wò ɖɔkta ate ŋu asusu AFLP le aklã ƒe dɔwɔwɔ ƒe ʋudodokpɔ me tsonu ta . Zi geɖe la, dodokpɔ siawo ɖea nuwo abe:

• Aklã me enzyme siwo dzi ɖe edzi.
• Kuxi siwo le wò ʋu ƒe sisi ƒe ɖoɖoa ŋu.
• Amonia, uric acid, kple protein ƒe agbɔsɔsɔ si le ʋua me ƒe dzidziɖedzi.
• Sukli ƒe agbɔsɔsɔ si bɔbɔ ɖe ʋu me.
• Dzesi siwo fia be ayiku gblẽ.

Dodokpɔ bubuwo

Be nàɖo kpe dɔlélea dzi la, wò ɖɔkta ate ŋu abia be woawɔ ultrasound scan alo CT scan . Esiawo ate ŋu ana aklãa ƒe nɔnɔmetata tsitotsito.

Aleke wowɔa atike na AFLP? (Atikewɔwɔ kaba le vevie!)

Be nàƒo asa na kuxi siwo ate ŋu ade wò agbe afɔku me la, wò ɖɔkta aɖo aɖaŋu na wò be nàdzi viwòa kaba ale si nàte ŋui . Ne woɖe vidzĩa kple vidzidɔa ɖa vɔ la, wò aklã adze hayahaya gɔme vivivi. Esiae nye dɔléle sia ƒe atike vevitɔ kple ɖeka kolia.

Ðe nane li mate ŋu awɔ atsɔ aɖe AFLP xɔxɔ ƒe afɔkua dzi akpɔtɔa?

Esia nye kuxi si le ame geɖe ŋu. AFLP nye nɔnɔme si mebɔ o. Eye, naneke meli nàte ŋu awɔ atsɔ axe mɔ ɖe enu alo ade dzesii do ŋgɔ o . Esiae nye dɔléle sia ƒe akpa wɔnublanui.

Nukae dzɔna ne AFLP le ŋunye?

Ne AFLP le ŋuwò la, ele be nàdzi viwòa enumake . Wò aklã ƒe dɔwɔwɔ adze egɔme anɔ abe ŋkeke 10 ene le vidzidzi megbe. Ahiã be kɔdzia ƒe ɖɔktawo nalé ŋku ɖe ŋuwò vaseɖe esime wò aklã dodokpɔ me tsonu natrɔ ava nɔ abe tsã ene.

Manya wɔ be nàgblɔ afɔku si tututu wònye be nàgaxɔ AFLP ake o. Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàdo domenyiŋusẽfianu kpɔ akpɔe ɖa be ami siwo me ami le siwo mesɔ o siwo ate ŋu anye esiwo na AFLP va dzɔ hã. Woate ŋu aɖo aɖaŋu hã be ne ègafɔ fu le etsɔme la, ele be vidada kple fugboe ƒe atikewɔwɔ ŋuti nunyala nalé ŋku ɖe wò fufɔfɔ ŋu .

Nukae gblẽ le vidzĩa ŋu?

Zi geɖe la, alesi gbegbe nɔnɔmea nu sẽe le vidadaa ŋue afia alesi gbegbe wògblẽa nu le vidzĩa ŋui. Vidzĩ aɖewo le afɔku me be woaxɔ dɔléle aɖe si woyɔna be nonketotic hypoglycemia (si nye ŋutetemanɔamesi be woatrɔ asi le amino acidwo ŋu nyuie). Ame bubuwo ate ŋu axɔ nɔnɔmewo abe dzitodzito me dɔléle si keke (dzi ƒe lãmeka si gbɔdzɔ) alo ahɔhɔ̃mekawo ƒe dɔléle (lãmekawo ƒe gbegblẽ). Gake zi geɖe la, afɔku si le vidzĩa ŋu medea afɔku si le vidadaa ŋu o.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ele vevie be nàgblɔ wò atikewɔwɔ ŋutinya bliboa na wò ɖɔkta le fufɔɣi eye nàna woanya nu tso dzesi ɖesiaɖe si le fu ɖem na wò ŋu. Anukwareɖiɖi akpe ɖe ŋuwò nàkpɔ atikewɔwɔ nyuitɔ kekeake si nèhiã.

Ne èkpɔ dzesi siwo gbɔna la dometɔ aɖe le fufɔɣi la, yi ɖɔkta enumake :

• Ƒodo alo akɔtave si medzona o.
• Ðeɖiteameŋu alo lãmetutudɔ si gbɔ eme.
• Ʋuʋudedi kple ʋuʋudedi si nɔa anyi ɖaa.
• Taɖuame si nu mayi o.

Esiawo ate ŋu anye fufɔfɔ ƒe dzesi siwo sɔ, gake woate ŋu anye nu vevi aɖe ƒe dzesi hã. Eyata mègake ɖi o.

Nya kawoe wòle be mabia nye ɖɔkta?

Bu eŋu kpɔ, ne wò ɖɔkta gblɔ na wò be AFLP le ŋuwò... esɔ be nyabiase geɖe nanɔ asiwò. Àte ŋu abia nyawo abe:

• "Ðɔkta, ɖe wòle be madzi vidzĩa fifiaa?"
• "Ðe nye agbe ɖo afɔku mea?"
• "Ðe vinyea ƒe agbe ɖo afɔku mea?"
• "Ðe AFLP ƒe nɔnɔme sia anyo ɖe edzia?"
• "Atikewɔwɔ ka ƒomevie mehiã?"
• "Ðe esia agadzɔ ake ne megafɔ fu akea?"
• "Nukatae esia dzɔ ɖe dzinye, ɖɔkta?"

Bia nya ɖesiaɖe si ŋu nàte ŋu abu alea. Mègalé naneke ɖe megbe o.

Vovototo kae le AFLP kple HELLP ƒe dɔlélea dome?

HELLP ƒe dɔléle ( Hemolysis, Elevated Liver Enzymes, and Low Platelet Count Syndrome)** nye dɔléle si dzɔna le fufɔɣi eye wòɖi AFLP tɔ. Vovototo vevitɔ si le nɔnɔme eveawo domee nye alesi ʋudodokpɔ me tsonu trɔna le ɣeyiɣi aɖe megbe. Zi geɖe la, AFLP lɔ kuxi siwo le ʋu ƒe sisi kple ʋumenugbagbevi dzĩwo ƒe agbɔsɔsɔ ƒe tɔtrɔ ɖe eme. Gake zi geɖe la, HELLP ƒe dɔlélea bia be ʋumenugbagbevi dzĩwo ƒe xexlẽme dzi ɖena kpɔtɔna vivivi.

Tsɔ kpe ɖe eŋu la, amesiwo ŋu AFLP le ate ŋu akpɔ:

• Nusiwo mesɔ o vevie le aklã ƒe dɔwɔwɔ dodokpɔwo me.
• Sukli ƒe agbɔsɔsɔ si le ʋu me ƒe masɔmasɔ ɖesiaɖe.
• Dzesi siwo fia be ayiku ƒe dɔwɔwɔ mesɔ o.
• Bilirubin ƒe agbɔsɔsɔ si sɔ (bilirubin nye gbeɖuɖɔ) le dodokpɔwo me.
• Acidosis (ʋua me acid ƒe dzidziɖedzi).
• (Proteinuria) .(Protein ƒe anyinɔnɔ le aɖuɖɔ me).
• Tɔtrɔ siwo vaa ahɔhɔ̃a ƒe dɔwɔwɔ me (e.g., ŋutete manɔamesi be wòabu tame nyuie, tɔtɔ).

Ðe wòsɔ be aklã si me ami le nanɔ ame ŋu le fufɔɣia?

Le amesiwo mefɔ fu o gɔ̃ hã gome la, aklãdɔ si me ami le nye dɔléle si bɔ, si woate ŋu ada. Ami aɖewo le ame akpa gãtɔ ƒe aklã me. Gake ne ami sia ƒo ƒu la, ate ŋu ana aklãa nawɔ dɔ nyuie. Esia nye afɔku vevietɔ le fufɔɣi , elabena wò aklãe nye mɔ si dzi ŋutilãa tona ɖea aɖinuwo ɖa. Ne wò aklã (alo viwòa ƒe aklã) mele dɔ wɔm nyuie o la, nusiwo gblẽa nu le ame ŋu ate ŋu aƒo ƒu ɖe wò ʋukawo me.

Mlɔeba la, nya siae wòle be magblɔ na mi (Take-Home Message) .

AFLP, alo aklãdɔ si nu sẽ le fufɔfɔ me, nye dɔléle si mebɔ o gake wòsẽa ŋu. Womate ŋu axe mɔ ɖe enu alo agblɔe ɖi o. Esia fia be ele vevie be nàƒo nu tso wò lãmesẽ ŋutinya kple dzesi ɖesiaɖe si mebɔ o si nàte ŋu akpɔ le wò fufɔɣi ŋu na wò ɖɔkta. Dzeɖoɖo siawo akpe ɖe wò ɖɔkta ŋu wòade dzesi kuxi siwo ate ŋu ado mo ɖa eye wòana atikewɔwɔ si nèhiã la wò.

Mègatsi dzodzodzoe o, gake kpɔ nyuie . Lé ŋku ɖe wò ŋutilã ŋu. Ne èse le ɖokuiwò me be nane si mebɔ o alo to vovo la, di atikewɔlawo ƒe aɖaŋuɖoɖo enumake. Nu vevitɔe nye be mia kple viwòa mianɔ lãmesẽ me.

` Aklã si me ami le le fufɔɣi, AFLP, fufɔfɔ ƒe kuxiwo, aklãdɔ, ʋuʋudedi, vidzidzi, LCHAD ƒe anyimanɔmanɔ