Àdi be yeanya wò CD4 Lãmenugbagbeviwo ƒe Xexlẽmea? Mina míaƒo nu!

Èse ``CD4 lãmenugbagbeviwo ƒe xexlẽme'' alo ``T-cell dodokpɔ'' ŋu nya kpɔa? Ðewohĩ wò ɖɔkta ƒo nu tso eŋu, alo ɖewohĩ èse nya siawo le afi aɖe. Togbɔ be adze nu sesẽ vie hã la, mina míadze agbagba ase egɔme bɔbɔe. Elabena esia nye dodokpɔ si gblɔa nyatakaka vevi geɖe na mí tso míaƒe dɔlélenutsiŋutete ƒe lãmesẽ ŋu.

Nukae nye CD4 lãmenugbagbeviwo ƒe xexlẽme?

Kpuie ko la, CD4 lãmenugbagbeviwo ƒe xexlẽme nye ʋudodokpɔ si me wodzidzea ʋumenugbagbevi ɣi ƒomevi aɖe koŋ ƒe xexlẽme le wò ʋu sue aɖe me. Ðɔktawo zãnɛ tsɔ kpɔa alesi HIV dɔlékuia kpɔ ŋusẽ ɖe wò dɔlélenutsiŋutete dzi kple alesi atikewɔmɔnuwo abe dɔlékuiwutike (ART) ene wɔa dɔe. Wozãnɛ hã ɣeaɖewoɣi tsɔ léa ŋku ɖe dɔléle bubuwo ŋu.

Ènya be HIV nye dɔlékui ƒe dɔléle si xɔa míaƒe agbemeŋkekewo katã si gblẽa míaƒe CD4 lãmenugbagbeviwo tẽ (si woyɔna hã be kpeɖeŋutɔ T-lãmenugbagbeviwo alo CD4+ T-lãmenugbagbeviwo). Eyata ne T-ʋumenugbagbevi siawo mesɔ gbɔ o la, ŋutete si le míaƒe ŋutilã ŋu be wòawɔ avu kple dɔlékuiwo hã mebɔna o.

Nukae nye CD4 ƒe alafa memamã?

Wò ɖɔkta ateŋu azã ``CD4 ƒe alafa memamã'' hã atsɔ akpɔ susu le wò dɔlélenutsiŋutete ƒe lãmesẽ ŋu. Wobua esia to ``CD4+ T cells'' ƒe xexlẽme mama ɖe ``lymphocytes'' (ʋumenugbagbevi ɣi ƒomevi bubu) ƒe xexlẽme bliboa dzi eye wodzi emetsonua ɖe edzi zi gbɔ zi 100.

Le go aɖewo me la, ŋkuléle ɖe `(CD4 lãmenugbagbeviwo ƒe xexlẽme)` ŋu ko ate ŋu anye nusi dzi womate ŋu aka ɖo boo o. Le kpɔɖeŋu me, ne dɔléle aɖe le ŋuwò si gblẽa nu le wò `(lymphocyte)` xexlẽme bliboa ŋu, alo na amewo abe ɖevi suewo, funɔwo, alo amesiwo xɔ wu ƒe 65 ene la, `(CD4 le alafa me)` ate ŋu aɖe vi wu.

Nukae míate ŋu asrɔ̃ tso CD4 ƒe xexlẽme me?

CD4 ƒe xexlẽme naa ɖɔktawo nyatakaka veviwo tso wò dɔlélenutsiŋutete ŋu. Ne xexlẽme sia sɔ gbɔ wu alesi wòle la, ate ŋu afia dɔlékuiwo, dɔléle bubuwo, alo HIV dɔlékuia ƒe ŋgɔyiyi.

Gake nu ɖeka aɖe li si dzi wòle be míaɖo ŋkui. Wò CD4 ƒe xexlẽme ate ŋu ato vovo vie tso ŋkeke yi ŋkeke. Esia ateŋu atso nuwo abe esime nèdo ʋu, nenye be dɔlékui aɖe nɔ ŋuwò ɣemaɣi, kple bubuawo gbɔ. Esia tae ɖɔktawo léa ŋku ɖe wò xexlẽme bliboa kple alesi wòtrɔna le ɣeyiɣi aɖe megbe ŋu.

Nukae wozãna na CD4 ƒe xexlẽme?

Azɔ mina míakpɔ nusi koŋ wozãa dodokpɔ sia na ɖa.

Ne HIV dɔlékuia le ŋuwò la:

Ne HIV dɔlékuia le ŋuwò la, ɖɔktawo zãa CD4 ƒe xexlẽme tsɔ:

• Kpɔ afisi HIV dɔlékuia le (i.e. afisi dɔlélea yi ŋgɔe).
• Lé ŋku ɖe alesi atikewɔwɔ si woyɔna be ``Antiretroviral Therapy - ART'' wɔa dɔ nyuie ŋu .
• Da afɔku si le asiwò be nàxɔ ``Mɔnukpɔkpɔ ƒe Dɔlékuiwo'' (dɔlékui sesẽ siwo dona bɔbɔe ne dɔlélenutsiŋutete gbɔdzɔ) la kpɔ.

Le go bubuwo me la:

Wozãa T-cell dodokpɔa ɣeaɖewoɣi na nuwo abe:

• Ne wodo ŋutinuwo na ame vɔ la, lé ŋku ɖe atike siwo tsia tre ɖe gbegbe nu ŋu.
• Lé ŋku ɖe atikewɔwɔ na dɔléle aɖewo siwo dɔlélenutsiŋutete hena vɛ ŋu.
• De dzesi ʋumenugbagbeviɣidɔ (si nye ʋumenugbagbeviɣidɔ ƒe kansa) ƒomevi aɖewo kple dɔlélewo abe DiGeorge ƒe dɔléle ene.

Ɣekaɣie wowɔa T-cell dodokpɔ siawo?

Ne wokpɔ HIV dɔlékuia le ŋuwò zi gbãtɔ la, wò ɖɔkta alé ŋku ɖe wò CD4 ƒe xexlẽme ŋu. Le ema megbe la, woayi edzi awɔ dodokpɔ sia be woakpɔ alesi nèle dɔ wɔm nyuie kple alesi wò atikewo le dɔ wɔm nyuie hã.

Ne èdze ART gɔme la, ahiã be woado wò CD4 lãmenugbagbeviwo ƒe xexlẽme kpɔ ɣleti etɔ̃ va ɖo ade ɖesiaɖe le gɔmedzedzea me. Le ɣeyiɣi aɖe megbe la, wò ɖɔkta ate ŋu atrɔ esia wòazu ɣleti ade va ɖo wuieve ɖesiaɖe . Woawɔ dodokpɔ bubu hã atsɔ akpɔ wò HIV dɔlékui ƒe agbɔsɔsɔ.

Aleke wowɔa CD4 lãmenugbagbeviwo ƒe xexlẽme dodokpɔ?

Ele bɔbɔe ŋutɔ. Nudokpɔƒe ƒe mɔ̃ɖaŋudɔwɔla zãa wò ʋu ƒe kpɔɖeŋu aɖe tsɔ dia wò ``CD4 xexlẽme.'' Woxlẽa ``T-cells'' siwo le wò ʋu ƒe kpɔɖeŋu me to mɔnu tɔxɛ aɖe si woyɔna be ``Flow Cytometry'' zazã me.Le esia me la, wotsɔa dzesi tɔxɛwo dea dzesi lãmenugbagbeviawo.

Aleke wòle be madzra ɖo ɖe dodokpɔ sia ŋu?

Dzadzraɖo tɔxɛ aɖeke mehiã o. Àte ŋu aɖu nu ahano wò atikewo abe alesi nèdi ene.

Nukae wòle be makpɔ mɔ na le dodokpɔa wɔɣi?

Ðɔkta alo dɔnɔdzikpɔla aɖe ʋu to aŋe sue aɖe dede ʋuka aɖe me le wò alɔnu me. Àte ŋu ase veve alo vevesese aɖe ne wotsɔ aŋea de eme heɖee, gake ɣeyiɣi kpui aɖe koe wòanɔ nenema. Emegbe woaɖo ʋua ɖe dodokpɔxɔ aɖe be woadoe kpɔ.

Afɔku kawoe le CD4 ƒe xexlẽme dodokpɔa me?

Afɔku siwo le dodokpɔ sia me la le sue ŋutɔ. Ɣeaɖewoɣi la, ate ŋu asesẽ vie ne ele be nàƒo aŋea zi geɖe be nàke ɖe ʋuka aɖe ŋu. Afɔku sue aɖewo li ne wole ʋu nom, abe:

• Sese le eɖokui me be taɖuame vie alo yeƒe tagbɔ gblẽ.
• Abi gã aɖe alo ʋu si ƒo ƒu ɖe ŋutigbalẽa te (hematoma).
• Dɔlékui aɖe xɔxɔ.
• Ʋu si nɔa dodom atraɖii (ƒã hafi esia dzɔna).

Nu ka ƒomevie míekpɔna tso eme?

Zi geɖe la, woɖea CD4 ƒe xexlẽme fiana abe lãmenugbagbeviwo ƒe xexlẽme le milimeta kubik ɖeka me ene (milimeta kubik ɖeka ƒe lolome anɔ abe ʋu ƒe dodo ene). Zi geɖe la, woŋlɔa esia be “mm3” alo “mcL” (microliters) le xexlẽdzesia megbe. Ɣeaɖewoɣi la, àkpɔ CD4 ƒe xexlẽme hã abe ʋumenugbagbevi dzĩwo (ʋumenugbagbevi ɣiwo) ƒe alafa memamã ene.

Nusiwo ado tso eme ate ŋu adze ale:

• CD4 ƒe xexlẽme si sɔ: 500mm3 va ɖo 1,200mm3
• CD4 ƒe xexlẽme si le sue: mede 500mm3 o
• CD4 ƒe xexlẽme si sɔ gbɔ: wu 1,200mm3

Asixɔxɔ siwo le dzidzenu "si sɔ" siawo ŋu, vevietɔ seɖoƒe si le etame, ateŋu ato vovo vie le dodokpɔxɔ aɖewo me. Eyata lé ŋku ɖe didime si sɔ ŋu le wò nyatakakaa me.

Nukae CD4 ƒe xexlẽme si bɔbɔ ɖe anyi fia?

Ne HIV dɔlékuia le ŋuwò la, ne CD4 ƒe xexlẽme mede o la, efia be dɔlékuia tsrɔ̃ wò ʋumenugbagbevi ɣi geɖe eye wògbɔdzɔ wò dɔlélenutsiŋutete. Esia dea afɔku gã aɖe me be dɔlékuiwo xɔxɔ, siwo dometɔ aɖewo ate ŋu ade wò agbe afɔku me. Ne wò CD4 xexlẽme nye 200mm3 alo esi mede nenema o la, efia be HIV ƒe afɔɖeɖe 3 lia le ŋuwò, si nye AIDS ƒe afɔɖeɖe.

Ne HIV mele ŋuwò o la, CD4 ƒe xexlẽme si bɔbɔ ate ŋu atso:

• Dɔlékui bubu aɖe hã.
• Atikewɔmɔnu nye kansa dada.
• Atike siwo gbɔdzɔa dɔlélenutsiŋutete (immunosuppressants).

Nukawo gbɔe CD4 ƒe xexlẽme dzina ɖe edzi tsona?

Dɔlékui aɖewo kple ʋumenugbagbeviɣidɔ ate ŋu ana CD4 ƒe xexlẽme nasɔ gbɔ wu alesi wòle be wòanɔ.

Ɣeyiɣi didi kae wòxɔna hafi míenyaa emetsonuwo?

Bia wò ɖɔkta ɣekaɣie nàxɔ wò CD4 xexlẽme ƒe dodokpɔ me tsonu kple alesi nàwɔ akpɔe (e.g. ɖe ɖɔktaa aƒo ka na wò alo aɖo nyatakaka ɖe wò). Zi geɖe la, woɖea ʋua hedonɛ kpɔna le gaƒoƒo 24 me, gake ate ŋu axɔ ɣeyiɣi didi hafi emetsonuwo nava.

Nukae dzɔna ne nye CD4 ƒe xexlẽme le sue?

Ne wò dodokpɔa me tsonu mesɔ abe alesi wò ɖɔkta kpɔ mɔe o la, ate ŋu abia tso asiwò be nàgawɔ dodokpɔa ake. Le wò dɔwɔwɔ me tsonu nu la, wò ɖɔkta ate ŋu awɔ nanewo abe:

• Wò atikewɔwɔ ƒe ɖoɖoa anɔ nenema, eye woabia tso asiwò be nàno wò CD4 ƒe xexlẽme si kplɔe ɖo kaba wu ŋkeke si woɖo ɖi va yi.
• Ne wò dɔlélenutsiŋutete gbɔdzɔ ŋutɔ la, woate ŋu aŋlɔ dɔlékuiwutikewo alo dɔlékuiwutikewo na wò be wòakpe ɖe ŋuwò nàxe mɔ ɖe dɔlékuiwo xɔxɔ nu.
• Woɖo aɖaŋu be nàtrɔ ``Antiretroviral - ART'' atike ƒomevi si nèzãna fifia.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Ne nya aɖe le asiwò ku ɖe wò dodokpɔa me tsonu ŋu la, ƒo nu kple wò ɖɔkta. Ne dɔlékui ƒe dzesiwo le ŋuwò (e.g., vevesese, abi, ʋuʋudedi, dzoxɔxɔ) la, yi xɔ si me wowɔa dɔ kpata le enumake.

Aleke mawɔ adzi nye CD4 ƒe xexlẽme ɖe edzi?

Zi geɖe la, dɔlékuiwutike (ART) wɔa dɔ ŋutɔ le HIV dɔlékui ƒe agbɔsɔsɔ dzi ɖeɖe kpɔtɔ le wò ŋutilã me (dɔlékui ƒe agbɔsɔsɔ) kple wò CD4 ƒe xexlẽme dzi ɖeɖe kpɔtɔ me. Gake ele be nàno atike sia abe alesi wogblɔe ene pɛpɛpɛ. Ne wò ART nono le sesẽm na wò la, ƒo nu tso eŋu na wò ɖɔkta.

Le go aɖewo me - na amesiwo me HIV dɔlékuia mele o, le kpɔɖeŋu me, ame aɖe si wodo ŋutinuwo na eye wòle dɔlélenutsiŋutete ƒe atikewo zãm - CD4 ƒe xexlẽme si bɔbɔ ate ŋu afia be woƒe atikewo le dɔ wɔm nyuie. Eyata, bia wò ɖɔkta nusi nàkpɔ mɔ na le wò nɔnɔmea nu.

Mlɔeba la, ɖo ŋku esia dzi (Take-Home Message) .

CD4 ƒe xexlẽme nye mɔ si dzi wò ɖɔkta ato akpɔ alesi HIV gblẽ nu le wò dɔlélenutsiŋutete ŋu kple alesi wò atikewɔwɔ le dɔ wɔm nyuie. Ɣeaɖewoɣi la, nu bubuwo ate ŋu akpɔ ŋusẽ ɖe emetsonuwo dzi, eyata mègavɔ̃ ne èkpɔ xexlẽme si mèle mɔ kpɔm na o. Ƒo nu kple wò ɖɔkta tso nusi emetsonuwo fia kple nenye be ehiã be nàwɔ tɔtrɔ aɖewo le wò atikewɔwɔ ƒe ɖoɖoa ŋu. Dɔlékuiwutike (ART) nono edziedzi ate ŋu akpe ɖe ŋuwò be HIV nagagblẽ nu le wò dɔlélenutsiŋutete ŋu o eye wòana wò T-cell ƒe xexlẽme nanɔ lãmesẽ me.

` CD4 xexlẽme, HIV, dɔlélenutsiŋutete, T-lãmenugbagbeviwo, ʋudodokpɔ, ART, atikewɔwɔ