Ðe dzesi siawo le ŋuwòa? Mina míaƒo nu tso Cushing Syndrome ŋu!

Èse Cushing Syndrome ŋkɔ kpɔa? Ðewohĩ ŋkɔa nye nu yeye vie na wò. Kpuie ko la, enye nɔnɔme si dzɔna ne míaƒe ŋutilã wɔ lãmetsi si nye cortisol . Ame aɖewo hã yɔnɛ be hypercortisolism. "Dzesi" nye dzesi siwo ƒoa ƒu ɖekae. Ðewohĩ èkpɔe be ame aɖewo yɔe be Cushing ƒe dɔléle.

Eyata nukae nye cortisol sia?

Cortisol nye steroid lãmetsi si le míaƒe ŋutilã me. Zi geɖe la, míeyɔnɛ be "nuteɖeamedzi ƒe lãmetsi" elabena ne míele nuteɖeamedzi me la, míaƒe ŋutilã ɖea cortisol geɖe ɖe go. Le ɣeyiɣi siawo me la, cortisol kpena ɖe mía ŋu:

• Wò dzi ƒe tsotso dzina ɖe edzi.
• Wò ʋu ƒe sisi le dzidzim ɖe edzi.
• Ekpɔa sukli ƒe agbɔsɔsɔ si le ʋu me dzi.
• Ekpɔa gbɔgbɔ dzi.
• Enaa lãmekawo ƒe tete ɖe edzi.

Menye ema ɖeɖeko o, ke ne míele nuteɖeamedzi me la, cortisol hã kpena ɖe mía ŋu míetsia ɖoɖo siwo mele vevie na míaƒe ŋutilã ɣemaɣi o hena ɣeyiɣi aɖe, le kpɔɖeŋu me, nuɖuɖumeŋusẽ kple vidzidzi ƒe dɔwɔwɔ.

Cortisol nye lãmetsi vevi aɖe na míaƒe ŋutilã. Cortisol le vevie na nu siawo:

• Lé ʋu ƒe sisi ɖe te.
• Dzra sukli ƒe agbɔsɔsɔ le ʋu me ɖo.
• Ðe dɔdzẽ dzi kpɔtɔ.
• Tu ŋkuɖodzinyawo ɖo.
• Dzra wò gbɔgbɔ dzi.
• Na dze nada asɔ le ŋutilãa me.
• Trɔ nuɖuɖu si míeɖuna wòazu ŋusẽ.

Lãmenugbagbevi sue eve siwo le míaƒe ayiku tame, siwo nye adrenal glands, pituitary gland si le ahɔhɔ̃a me, kple hypothalamus, si le pituitary gland tame, ye kpɔa cortisol ƒe agbɔsɔsɔ dzi.

Zi geɖe la, dɔdzẽ aɖe gbɔe Cushing ƒe dɔlélea tsona . Esia ate ŋu adzɔ le mɔ vevi eve nu:

• Endogenous: Esia fia be enye nɔnɔme si cortisol si dona le míaƒe ŋutilã me hena vɛ.
• Exogenous: Esia fia be gotagomenuwo gbɔe nɔnɔme aɖe tsona abe atike aɖewo siwo wozãna tsɔ daa atikewɔwɔ me nɔnɔme bubuwo ƒe nugbegblẽ le ame ŋu ene.

Amekae ate ŋu axɔ Cushing Syndrome wu?

Cushing ƒe dɔlélea bɔ ɖe ɖeviwo, sɔhɛ tsitsiwo, kple ame tsitsiwo me wu. Ebɔ ɖe amesiwo xɔ tso ƒe 25 va ɖo ƒe 50. Ame siwo noa atike siwo me cortisol le (le kpɔɖeŋu me, asrã kple ƒunukpeƒetetedɔ ƒe atikewo) la ate ŋu axɔ dɔlélea. Ame siwo ŋu Cushing ƒe dɔlélea le la dometɔ siwo ade 70% nye nyɔnuwo eye 30% nye ŋutsuwo.

Aleke gbegbee nɔnɔme sia bɔe?

Cushing ƒe dɔlélea nye dɔléle si mebɔ kura o , eye wòdzea ame 40 va ɖo 70 le miliɔn ɖeka me ƒe sia ƒe.

Vovototo kae le Cushing Dɔléle kple Cushing Dɔléle dome?

Cushing ƒe dɔlélea nye Cushing ƒe dɔléle ƒomevi aɖe. Dɔdzẽ si me dɔlékui aɖeke mele o si le lãkusi si me ʋu sina tona me gbɔe wòtsona. Dɔdzẽ sia ɖea lãmetsi si nye ACTH (adrenocorticotropic hormone) ƒe akpa gãtɔ ɖe go . Esia nana be adrenal glands la ɖea cortisol fũu akpa.

Le amesiwo ŋu Cushing ƒe dɔlélea le dome la, Cushing ƒe dɔléle sia ƒomevi le ame tsitsi siwo wu 70% kple ɖeviwo kple sɔhɛ tsitsiwo ƒe 60% va ɖo 70% dome.

Ðɔkta ka ƒomevie daa Cushing Dɔlélea?

Wò ɖɔkta gã aɖe aɖo wò ɖe eŋutinunyala bibi aɖe si woyɔna be lãmenugbagbeviwo ƒe dɔwɔwɔ ŋuti nunyala gbɔ be wòakpɔ dɔléle sia ahadae.

Ðe Cushing Dɔlélea ate ŋu awu amea?

Ẽ, Cushing ƒe Dɔlélea ate ŋu awu ame ne womedae nyuie o. Ne womewɔ atike nɛ o la, cortisol ƒe agbɔsɔsɔ gbogbo sia (hypercortisolism) ate ŋu ahe lãmesẽkuxi vovovowo vɛ. Le kpɔɖeŋu me:

• Dɔlékuiwo
• Ʋu ƒe sisi, vevietɔ le lãkusi kple afɔwo me
• Teteɖeanyi
• Dzidɔ
• Kpekpeme ƒe dzidziɖedzi
• Ŋkuɖodzikuxiwo alo susu ƒe dɔwɔwɔ sesẽ
• Ʋusɔgbɔdɔ alo ʋumemi ƒe agbɔsɔsɔ fũ
• Ƒu siwo gbã
• Suklidɔ ƒomevi 2 lia, suklidɔ si do ŋgɔ na suklidɔ, alo suklidɔ si gblẽna le nutsitsidɔ me

Ne womeda Cushing ƒe dɔlélea o la, ate ŋu ana ame naku gɔ̃ hã.

Nukawoe hea Cushing Syndrome vɛ?

Cortisol si sɔ gbɔ ɖe ŋutilãa me gbɔe Cushing ƒe dɔlélea tsona. Nu geɖe li siwo ate ŋu ana esia nadzɔ:

• Glucocorticoid Atikewo Zazã: Wozãa glucocorticoid atikewo (le kpɔɖeŋu me, prednisone) tsɔ daa asrã si nɔa anyi didi, ƒunukpeƒetetedɔ, lupus, sarcoidosis, kple dɔléle bubu geɖe siwo dɔlékuiwutikewo tsona siwo hea abi si nɔa anyi didi vɛ. Atike siawo nono ɣeyiɣi didi ateŋu ahe "iatrogenic" alo exogenous Cushing syndrome vɛ. Nya "iatrogenic" fia be nu bubu aɖe tso atikewɔmɔnu aɖe gbɔ.
• Pituitary tumors: Cushing syndrome ( iatrogenic Cushing syndrome mele eme o) tsoa pituitary tumors siwo wɔa ACTH, si nye lãmetsi si gblɔna na adrenal glands be woawɔ cortisol fũu akpa gbɔ, eye wòdzea ame 8 le 10 ɖesiaɖe me dzi. Woyɔa esia ƒomevi be Cushing dɔléle.
• Adrenal cortical tumors: Dɔdzẽ si dona ɖe adrenal gland tame ate ŋu awɔ cortisol fũ akpa. Zi geɖe la, esiawo nyea dɔdzẽ siwo me dɔlékui aɖeke mele o. Gake ɣeaɖewoɣi la, dɔdzẽ sia ate ŋu anye adrenal cortical carcinoma, si nye adrenal cancer ƒomevi aɖe si mebɔ kura o.
• Aklã, dɔgbo, lãkusi kple lãkusi me dɔdzẽ: Ne dɔdzẽ siwo le lãkusia godo ye wɔ ACTH la, woyɔnɛ be ectopic ACTH syndrome. Zi geɖe la, dɔdzẽ siawo nyea dɔlékui vɔ̃ɖiwo. Esiawo dometɔ si bɔ wue nye lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ.

Ðe Cushing Dɔlélea tso domenyiŋusẽfianu mea?

Zi geɖe la, ao . Cushing ƒe dɔlélea ƒe akpa gãtɔ menye domenyiŋusẽfianu o.

Nukawoe nye Cushing Syndrome ƒe dzesiwo?

Tsɔ kpe ɖe dzesi siwo ku ɖe Cushing ƒe dɔlélea ŋu koŋ ŋu la, dzesi aɖewo hã li siwo ate ŋu abɔ ɖe nɔnɔme bubu geɖe me. Menye amesiamee akpɔ dzesi ɖeka o. Esiawoe nye dzesi siwo ate ŋu ado mo ɖa:

• Kpekpeme ƒe dzidziɖedzi kabakaba le mo (ame aɖewo yɔa esia be "ɣleti mo"), ƒodo ƒe akpa, kɔ megbe (ame aɖewo yɔa esia be "nyitsu ƒe ʋuʋudedi"), kple akɔta.
• Mo dzĩ si le goglo.
• Abi xɔa ɣeyiɣi hafi wohaya.
• Ʋusɔgbɔdɔ (ʋusɔgbɔdɔ).
• Taɖa ƒe tsitsi fũ akpa le mo, kɔ, akɔta, dɔgbo, no, kple ata, alo ɖa ƒe vuvu (taɖa).
• Suklidɔ.

Dzesi bubuwo ate ŋu anye:

• Dzesi siwo ƒe amadede nye aŋutiɖiɖi ƒe dzedzeme le ƒodoa ƒe akpa si.
• Asiwo kple afɔwo ƒe ƒoƒo bɔbɔe.
• Gbɔdzɔgbɔdzɔ le goawo katã me kple ɖeɖiteameŋu.
• Nukpɔkpɔ si me mekɔ o kple taɖuame.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ kple abɔ kple afɔ ƒe gbegblẽ.
• Gbɔdɔdɔ ƒe dzodzro ƒe tɔtrɔ kple tsitretsitsi ƒe dɔmawɔmawɔ nyuie le ŋutsuwo me.
• Ðeviwo ƒe tsitsi ƒe gbegblẽ.

Ɣeyiɣi didi kae Cushing Dɔlélea nɔa anyi?

Ɣeyiɣi didi si Cushing ƒe dɔlélea anɔ te ɖe alesi nàwɔ nui ɖe atikewɔwɔ ŋu dzi. Ame akpa gãtɔ siwo ŋu cortisol sɔ gbɔ ɖo (hypercortisolism) la hayana le atikewɔwɔ kwasiɖa ʋɛ aɖewo megbe.

Ðe Cushing Syndrome nana gbɔgbɔtsixe tsia amea?

Ao.Gbɔgbɔ tsitsi menye Cushing ƒe dɔlélea ƒe dzesi si ɖe dzesi o.

Ðe Cushing Syndrome hea ƒumeŋuɖui vɛa?

Ɛ̃. Cushing ƒe dɔlélea ate ŋu ana ƒuwo nagbɔdzɔ. Esia ate ŋu ana nàgbã, vevietɔ ne dɔlélea le ŋuwò ɣeyiɣi didi aɖe. Ƒu siwo gbɔdzɔ hã ate ŋu ana ame nase veve.

Ðe Cushing Dɔlélea hea ʋumenugbagbeviɣidɔ vɛa?

Hypokalemia nye nɔnɔme si me potassium ƒe agbɔsɔsɔ si le wò ʋu me medea ame dzi o. Nɔnɔme sia ate ŋu ado mo ɖa ne Cushing ƒe dɔlélea le ŋuwò.

Aleke wowɔna kpɔa Cushing Dɔlélea?

Ne wò ɖɔkta susui be cortisol sɔ gbɔ (hypercortisolism) la, mɔfiame aɖewo li siwo dzi woawɔ ɖo. Woabia nyawo, awɔ wò atikewɔwɔ ŋutinya, awɔ wò ŋutilã dodokpɔ, eye emegbe woaɖe gbe be woawɔ dodokpɔ aɖewo le dodokpɔxɔ me. Woate ŋu alé ŋku ɖe ŋuwò hã hena ɣeyiɣi aɖe.

Cushing ƒe dɔlélea ate ŋu asesẽ vie ɣeaɖewoɣi be woakpɔe. Ne ègblɔ na wò ɖɔkta be ɖeɖi te ye ŋu eye yeƒe lolo le dzidzim ɖe edzi la, ɖewohĩ womabu Cushing ƒe dɔlélea ŋu enumake o. Esia le alea elabena dzesi siawo bɔ ɖe dɔléle vovovo geɖewo me.

Azɔ hã, woate ŋu atɔtɔ Cushing ƒe dɔlélea ɣeaɖewoɣi kple polycystic ovary syndrome alo metabolic syndrome . Ahiã be wò ɖɔkta naɖe nɔnɔme bubuwo ɖa hafi ate ŋu anya dɔlélea.

Dodokpɔ kawoe wowɔna tsɔ dea dzesi Cushing Syndrome?

Wò ɖɔkta ate ŋu awɔ dodokpɔ siawo dometɔ aɖewo:

• Gaƒoƒo 24 ƒe aɖuɖɔtoe me cortisol dodokpɔ: Dodokpɔ sia dzidzea cortisol agbɔsɔsɔme si le wò aɖuɖɔ me le microgram (mcg) me. Wò ɖɔkta abia tso asiwò be nàxɔ wò aɖuɖɔ le gaƒoƒo 24 me.
• Zãtitina aɖuɖɔ me cortisol dodokpɔ: Zi geɖe la, cortisol ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna ŋutɔ le zã me. Dodokpɔ sia léa ŋku ɖe cortisol ƒe agbɔsɔsɔ ŋu le ŋdi ga 11 kple 12 dome. Ne Cushing ƒe dɔlélea le ŋuwò la, wò cortisol ƒe agbɔsɔsɔ asɔ gbɔ le mɔ si mesɔ o nu ɣemaɣi.
• Dexamethasone ƒe agbɔsɔsɔ sue aɖe ƒe nutete dodokpɔ:Dexamethasone nye atike si ɖi cortisol. Le dodokpɔ sia gome la, ènoa atike sia miligram ɖeka (mg) to nu me le zã me, eye emegbe wodzidzea wò cortisol ƒe agbɔsɔsɔ le ŋdi ga 8 kple 9 dome. Ʋudodokpɔ sia léa ŋku ɖe eŋu nenye be wò adrenal glands wɔ nu ɖe ​​dexamethasone ŋu to cortisol si woɖena ɖe go dzi ɖeɖe kpɔtɔ me. Ne Cushing ƒe dɔlélea le ŋuwò la, wò cortisol ƒe agbɔsɔsɔ asɔ gbɔ.
• Ʋudodokpɔ: Ʋudodokpɔ dzidzea ACTH ƒe agbɔsɔsɔ le wò ʋu me. Ne ACTH ƒe agbɔsɔsɔ le sue la, ke ate ŋu anye be adrenal tumor le ŋuwò. Ne agbɔsɔsɔa sɔ alo esɔ gbɔ la, ke ate ŋu anye be dɔdzẽ le dɔgboa me alo dɔdzẽ si le vidzidɔa godo.
• Dexamethasone ƒe agbɔsɔsɔme si sɔ ƒe dodokpɔ: Esia sɔ kple dexamethasone ƒe agbɔsɔsɔ sue ƒe dodokpɔ, gake agbɔsɔsɔme si wozãna nye miligram 8 ɖe 1. Zi geɖe la, wowɔa dodokpɔ sia ne dodokpɔ si me wozãa atike suewo le ɖee fia be cortisol sɔ gbɔ ɖe lãme na ame le ŋdi me eye ʋudodokpɔwo ɖee fia be ACTH sɔ gbɔ ɖe ʋua me vɔ. Dodokpɔ sia ate ŋu akpe ɖe ame ŋu woake ɖe nusi gbɔ Cushing ƒe dɔlélea tso ŋu. Ate ŋu akpe ɖe ŋuwò nàde vovototo pituitary adenoma (si wogayɔna be Cushing ƒe dɔléle) kple dɔdzẽ si le wò ŋutilã ƒe akpa bubu (abe le lãkusi me ene) dome.

Ne wò ɖɔkta nya ɖo kpe edzi be Cushing ƒe dɔlélea le ŋuwò ko la, afɔɖeɖe si kplɔe ɖoe nye be nànya nusi gbɔ wòtso. Zi geɖe la, ate ŋu anye atike alo dɔdzẽ. Ne èle glucocorticoids nom la, anɔ eme be ema gbɔe wòtso, eyata wò ɖɔkta ate ŋu aɖe wò agbɔsɔsɔme dzi akpɔtɔ. Ne mèle glucocorticoids nom o la, ate ŋu afia be dɔdzẽ aɖe le wò adrenal glands, pituitary gland, alo teƒe bubu aɖe. Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ nɔnɔmetatawo ŋuti numekukuwo abe esiawo ene be wòakpe ɖe ŋuwò nàke ɖe dɔdzẽa ŋu:

• CAT scan (CT scan) alo MRI ƒodo: Wò ɖɔkta ate ŋu awɔ CT scan alo MRI atsɔ akpɔe ɖa be dɔdzẽ le wò adrenal glands me hã. Woate ŋu awɔ fotoɖeɖe siawo kple vovototodedeameme si wodona ɖe ʋuka me (IV contrast) alo womawɔe o. Dodokpɔ siawo te ŋu dea dzesi adrenal tumors ŋutɔ.
• Magnetic resonance imaging (MRI) si woɖena le lãkusi me:MRI ɖea wò lãkusi ƒe foto tsɔ dia dɔdzẽ aɖe. Le go aɖewo me la, MRI menye dɔlélea didi bliboe o. Ame siwo ŋu Cushing ƒe dɔlélea le la dometɔ siwo ade 50% ƒe MRI "si sɔ" le wo si, gake 10% ate ŋu anye be dɔdzẽ siwo medo ƒome kple dɔlélea o le 10% ŋu.
• Bilateral inferior petrosal sinus sampling (BIPPS): Dodokpɔ sia kpɔ afisi ACTH ƒe dodo tso. ACTH kple lãkusi me lãmetsi bubuwo dona tso lãkusi me yia ʋukawo me. Kekeliŋutinunyala bibi aɖe si dea nu nyaa me wɔa dodokpɔ sia to ʋuka eve siwo woyɔna be inferior petrosal sinuses dzi. Dodokpɔ sia ƒe nyateƒetoto le 95% va ɖo 98% dome.
• CT scan akɔta: Ne wò ɖɔkta susui be dɔdzẽ aɖe le vidzidɔa godo la, ate ŋu abia be woawɔ CT scan na akɔta be woakpɔe ɖa be dɔdzẽ si ate ŋu adzɔ le aɖuɖɔtoe me hã.

Aleke wodaa Cushing Dɔléleae?

Atikewɔwɔ ƒe ƒomevi nɔ te ɖe nusi gbɔ cortisol ƒe agbɔsɔsɔ si sɔ gbɔ tsoe dzi. Ne èle glucocorticoid nom la, anɔ eme be wò ɖɔkta aɖe wò agbɔsɔsɔme dzi akpɔtɔ alo aŋlɔ atike si menye glucocorticoid o na wò.

Ne dɔdzẽ aɖe gbɔe Cushing ƒe dɔlélea tso la, wò ɖɔkta ate ŋu ado susu ɖa be woawɔ dɔ nɛ alo awɔ keklẽŋusẽdɔdamɔnu.

Mɔnu bubue nye be wò ɖɔkta naŋlɔ atike aɖe si ɖea cortisol ƒe wɔwɔme dzi kpɔtɔna, abe ketoconazole ene, na wò. Ðewohĩ ahiã be nàwɔ dɔ kple ɖɔkta vovovo geɖe atsɔ ada dɔdzẽa kple Cushing ƒe dɔlélea ƒe dzesiwo.

• Atikewɔmɔnu: Ne kansa le dɔdzẽ aɖe ŋu eye wòkaka ɖe ŋutilã ƒe akpa bubuwo la, ke ahiã be woawɔ atike na ame. Kpɔ egbɔ be yeƒo nu kple wò ɖɔkta tso eƒe nugbegblẽ le ame ŋu ɖesiaɖe ŋu.
• Atikewo: Atike siwo ɖea cortisol dzi kpɔtɔna tsɔtsɔ kpee alo atike siwo ate ŋu ahe Cushing ƒe Dɔlélea vɛ ɖeɖeɖa.
• Kekeli: Ðewohĩ womawɔ dɔ na dɔdzẽ si le lãkusi me la ɖa o. Le nɔnɔme mawo me la, ɖewohĩ ahiã be woawɔ keklẽŋusẽdɔdamɔnu na wò kwasiɖa ade. Ate ŋu axɔ ƒe geɖe hafi cortisol ƒe agbɔsɔsɔ natrɔ ava nɔ abe tsã ene. Ðo dze kple wò ɖɔkta tso eƒe nugbegblẽ le ame ŋu ɖesiaɖe ŋu.
• Amekoko:Amekoko ƒe ʋuka me dɔdzẽ, adrenal ƒe dɔdzẽ, kple vidzidɔ godo ƒe dɔdzẽ ɖeɖeɖa kpɔa dzidzedze, gake ahiã be nàtrɔ ɖe cortisol ƒe agbɔsɔsɔ yeye si bɔbɔ ɖe anyi la ŋu. Le ɣeyiɣi sia me la, ahiã be nàno cortisol atike siwo nye hydrocortisone atikekuiwo. Àte ŋu adzudzɔ atike sia nono le ɣleti 6 va ɖo 18 megbe. Zi geɖe la, ne wowɔ dɔ na wò to dɔgboa me vɔ la, àte ŋu ado le kɔdzi le ŋkeke ɖeka alo eve megbe.

Ne woda Cushing ƒe dɔlélea nyuie la, ate ŋu axɔ ɣleti 2 va ɖo 18 hafi wòahaya. Nɔ kadodo kplikplikpli me kple wò ɖɔkta le ɣeyiɣi sia me kple emegbe.

Nukae mate ŋu akpɔ mɔ na ne Cushing Syndrome le ŋunye?

Wò ɖɔkta ate ŋu ada Cushing ƒe dɔlélea eye ele be wòadae hã. Ne womewɔ atike nɛ o la, ate ŋu awu ame. Kpɔ ɖɔkta kaba ale si nàte ŋui be nàdzro wò dzesiwo me kple wò ɖɔkta.

Ðe Cushing Dɔlélea ate ŋu agblẽ ɖe edzia?

Cushing ƒe dɔlélea ate ŋu agblẽ ɖe edzi ne womedae nyuie o. Nɔ kadodo me kple wò ɖɔkta eye nàna woanya nu tso dzesi yeye ɖesiaɖe, dzesi siwo le gbegblẽm ɖe edzi, alo kuxi bubu ɖesiaɖe ŋu.

Aleke mawɔ aɖe Cushing Syndrome ƒe afɔkua dzi akpɔtɔ alo axe mɔ ɖe enu?

Wò ŋutilã hiã cortisol ɣesiaɣi. Èhiãe be nànɔ dɔ dzi. Ekpɔa ŋusẽ ɖe wò gbɔgbɔ dzi, etrɔa nuɖuɖu si nèɖuna wòzua ŋusẽ, enaa sukli ƒe agbɔsɔsɔ le ʋu me nɔa asiwò, ekpena ɖe ŋuwò nèkpɔa nuteɖeamedzi gbɔ, eye wòwɔa nu geɖe wu. Cortisol menye wò ŋutilã ƒe futɔ o, gake eƒe agbɔsɔsɔ fũ menyo o. Gake màte ŋu anɔ agbe cortisol manɔmee o.

Ne èle glucocorticoids alo steroids zãm la, na wò ɖɔkta nalé ŋku ɖe wò cortisol ƒe agbɔsɔsɔ ŋu nyuie. Nublanuitɔe la, mɔ aɖeke meli si dzi woato axe mɔ na dɔdzẽ be wòagahe Cushing ƒe Dɔléle (hypercortisolism) vɛ o.

Aleke wòle be woanɔ agbe kple Cushing Syndrome?

Agbenɔnɔ kple Cushing ƒe dɔlélea ate ŋu asesẽ, gake mehiã be wòanye nɔnɔme si ate ŋu ade ame ƒe agbe afɔku me o. Ðɔkta aɖewo li siwo wona hehee be woakpe ɖe ŋuwò, eye atikewɔmɔnu hã li. Zi geɖe la, atikewɔwɔ siawo ate ŋu ada Cushing ƒe dɔlélea eye woana cortisol ƒe agbɔsɔsɔ si sɔ gbɔ (hypercortisolism) ƒe dzesiwo nanyo ɖe edzi.

Cushing ƒe dɔlélea ate ŋu ana nàto seselelãme kple hadomekuxi aɖewo me. Ame aɖewo ate ŋu akpe ŋu le taɖa ƒe ŋeŋe, taɖa ƒe tsitsi fũ, kple/alo lolo si le mo kple kɔ megbe ta. "Moon face" kple "buffalo hump" ateŋu ana nàbu tame zi eve le gomekpɔkpɔ le hadome nɔnɔmewo me ŋu. Le ɣeyiɣi aɖe megbe la, atikewɔwɔ ate ŋu akpe ɖe ame ŋu be dzesi siawo nanyo ɖe edzi. Cushing ƒe dɔlélea ate ŋu ahe blanuiléle kple tagbɔdɔ bubuwo hã vɛ. Ne ehiã la, yi atikewɔla gbɔ hena aɖaŋuɖoɖo kple tagbɔdɔdala hena atike be wòakpe ɖe ŋuwò nàkpɔ seselelãme ƒe ŋusẽkpɔɖeamedzi siwo cortisol ƒe agbɔsɔsɔ si sɔ gbɔ (hypercortisolism) hena vɛ gbɔ.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Kpɔ ɖɔkta ne Cushing ƒe dɔlélea ƒe dzesi siawo dometɔ aɖe le ŋuwò:

Dzesi siwo gblẽa nu le nyɔnuwo koŋ ŋu:

• Mo ƒe fu yeye alo esi gbɔ eme ƒe tsitsi.
• Tɔtrɔ le gbɔdɔdɔ ƒe dzodzro ŋu.
• Tɔtrɔ le dzinukpɔkpɔ me.

Dzesi siwo gblẽa nu le amesiame ŋu:

• Kpekpeme ƒe dzidziɖedzi kabakaba le mo (ame aɖewo yɔa esia be "ɣleti mo"), ƒodo ƒe akpa, kɔ megbe (ame aɖewo yɔa esia be "nyitsu ƒe ʋuʋudedi"), kple akɔta.
• Mo dzĩ si le goglo.
• Ʋusɔgbɔdɔ (ʋusɔgbɔdɔ).
• Taɖa ƒe tsitsi fũ akpa le mo, kɔ, akɔta, ƒodo, kple ata.
• Suklidɔ.
• Aklã yeye alo esi gbɔ eme.
• Dzesi siwo ƒe amadede nye aŋutiɖiɖi ƒe dzedzeme le ƒodoa ƒe akpa si.
• Asiwo kple afɔwo ƒe ƒoƒo bɔbɔe.
• Gbɔdzɔgbɔdzɔ le goawo katã me kple ɖeɖiteameŋu.
• Nukpɔkpɔ si me mekɔ o kple taɖuame.
• Abi xɔa ɣeyiɣi hafi wohaya.
• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ.

Nya kawoe wòle be mabia nye ɖɔkta?

• Atike kawoe mate ŋu ano atsɔ akpe ɖe nye Cushing ƒe dɔlélea ŋu?
• Ðe kamedede aɖewo li mate ŋu awɔ atsɔ akpe ɖe nye lãmeka siwo gbɔdzɔ ŋua?
• Ðe atike aɖewo li siwo woate ŋu azã atsɔ akpe ɖe ame ŋu le lãmekawo ƒe ʋuʋu ŋua?
• Ðe wòle be makpɔ Cushing Syndrome ƒe dɔdala bibi aɖea?
• Ðe wòhiã be madzudzɔ atike siwo zãm mele fifia dometɔ aɖe nonoa?
• Nukae nye atikewɔwɔ nyuitɔ kekeake nam?
• Ðe mɔxexeɖedɔléle nu ƒe afɔɖeɖe bubu aɖewo li siwo wòle be mawɔa?

Cushing ƒe dɔlélea ate ŋu anye nɔnɔme sesẽ aɖe si gbɔ kpɔkpɔ. Ate ŋu ana ame nagbɔdzɔ, ʋusɔgbɔdɔ, kple ɖeɖiteameŋu. Atikewɔwɔwo abe amekoko, atikewo zazã, keklẽŋusẽdɔdamɔnu, kple atikewo zazã ate ŋu asesẽ. Gake viɖe le wo ŋu, elabena ne wowɔ atike nyuitɔ la, woate ŋu ada Cushing ƒe dɔlélea.

Kpuie ko la (Gbedasi si Wotsɔ Yi Aƒeme) .

Cushing ƒe Dɔléle nye dɔléle si tsoa lãmetsi si nye cortisol ƒe dzidziɖedzi le míaƒe ŋutilã me gbɔ. Esia mebɔ vie o, gakeNe wokpɔ dɔlélea le eŋu eye wodae nyuie la, woate ŋu adae . Ele vevie ŋutɔ be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo ne dzesiwo abe mo ƒe vuvu, lolo, taɖa ƒe tsitsi fũ, alo ʋusɔgbɔdɔ ene le ŋuwò. Atikewɔwɔ ƒe tiatia vovovowo le nusi gbɔ wòtso nu. Eyata ƒo nu tso nusianu ŋu kple wò ɖɔkta eye nàwɔ ɖe woƒe aɖaŋuɖoɖowo dzi. Ðo ŋku edzi be menye wò ɖeka koe o, eye kpekpeɖeŋu li.

` Cushing ƒe Dɔléle, cortisol, lãmetsiwo, adrenal glands, pituitary gland, ACTH, dzesiwo, atikewɔwɔ, lãmenugbagbeviwo ŋuti nunyala