Ðe esia gbɔe wò dɔgbo ƒe vevesese kple dɔdzẽ tsona? Mina míasrɔ̃ nu tso Eosinophilic Gastritis ŋu!

Ðe dɔgbo me kuxiwo, fuɖename, kple nuɖuɖu megadzroa wò hã zi geɖea? Ɣeaɖewoɣi la, le dzesi siawo megbe la, dɔléle aɖe ate ŋu anɔ anyi si ŋu míese nu tsoe boo o, gake ele be míatsi dzi vie. Dɔléle mawo dometɔ ɖekae nye Eosinophilic Gastritis . Egbea, míaƒo nu tso esia ŋu bɔbɔe, le mɔ si gɔme nàte ŋu ase nu.

Nukae nye eosinophilic gastritis (EG)?

Kpuie ko la, eosinophilic gastritis (EG) nye dɔléle si mebɔ o si gblẽa nu le wò dɔgbo ŋu . Eosinophils, si nye ʋumenugbagbevi ɣi ƒomevi aɖe si le míaƒe ŋutilã me, ƒoa ƒu ɖe dɔgboa ƒe gliwo me eye wònaa dɔdzẽ , si fia be evuvu eye wògblẽa nu. Bu eŋu kpɔ, ɖeko míaƒe dɔgbo ƒe gli biãna eye wòvuvuna.

Ate ŋu adze amesiame si xɔ ƒe ɖesiaɖe dzi, eye enye dɔléle si nɔa anyi didi , si fia be enɔa anyi didi. Gake mègatsi dzi o, wò ɖɔkta ate ŋu akpe ɖe ŋuwò nàkpɔ dzesi siawo gbɔ. Esia ate ŋu abia nuwo abe dodokpɔ edziedzi kple nuɖuɖu ƒe tɔtrɔ ene.

Nukae nye eosinophil siawo?

Azɔ mina míakpɔ nusiwo nye eosinophils siawo ɖa. Esiawo nye ʋumenugbagbevi ɣi ƒomevi aɖe si le míaƒe ŋutilã me. Wole abe asrafo sue siwo le míaƒe dɔlélenutsiŋutete me ene . Woƒe dɔ vevitɔe nye be woawɔ avu kple dɔlékuiwo kple dɔlékui siwo gena ɖe míaƒe ŋutilã me.

Zi geɖe la, esiawo dzɔna le míaƒe ƒumeŋuɖui me , gake le agbɔsɔsɔ sue aɖe me. Eosinophils siawo nye ʋumenugbagbevi ɣiwo katã ƒe 1% va ɖo 5% le ame si le lãmesẽ me me.

Gake le nulɔdɔ , dɔlékui, atike aɖewo, alo kansa ta la, eosinophils siawo ate ŋu adzi ɖe edzi zi ɖeka. Esiae nye nusi míeyɔna be eosinophilia . Lãmenugbagbevi siawo ɖea atikewo abe enzyme kple protein ene ɖe go tsɔ tsrɔ̃a lãmenugbagbevi siwo mele lãmesẽ me o. Eyata ne eosinophil siawo siwo le ŋutilãa me dzi ɖe edzi la, wodzea mía ŋutɔwo ƒe lãkusiwo dzi dzedze gɔme. Emegbe , dɔgbo ƒe lãkusiwo ƒe dɔdzẽ (gastritis) alo ŋutinu bubuwo ƒe dɔdzẽ ate ŋu adzɔ.

Ameka ŋue eosinophilic gastritis (EG) gblẽa nu le wu?

Nɔnɔme sia si woyɔna be eosinophilic gastritis (EG) ate ŋu adze ame siwo xɔ ƒe ɖesiaɖe dzi. Esia fia be ate ŋu adze vidzĩwo kple ame tsitsiwo siaa dzi. Gake zi geɖe la, ɖɔktawo dea dzesii le ame tsitsi siwo xɔ tso ƒe 30 va ɖo ƒe 50. Azɔ hã, le akɔntabubu nu la, ŋutsuwo ate ŋu axɔ dɔléle sia vie wu nyɔnuwo.

Ne nulɔdɔ le ŋuwò kpɔ , alo ne dɔléle aɖe le wò ƒomea me la, àte ŋu anɔ afɔku me vie be nàxɔ EG. Ame geɖe siwo xɔa EG la ƒe nulɔdɔwo abe:

• Asrãdɔ
• Nuɖuɖu ƒe dɔmawɔmawɔ nyuie alo nuɖuɖu ƒe nulɔdɔ (le kpɔɖeŋu me, notsi, azi, luwɔ) .
• Hay fever / allergic rhinitis (nɔnɔme si ƒe dzesi enye aɖuɖɔɖɔɖɔ enuenu kple ŋɔti me tsi si le dodom) .
• No me tsi si sina enuenu (rhinitis) .
• Ŋutilã me ʋuʋudedi, nɔnɔmewo abe eczema ene

Nukawoe nye eosinophilic intestinal disease (EGID) ƒomeviwo?

Eosinophilic gastritis (EG) nye dɔlélewo ƒe hatsotso gã aɖe si woyɔna be Eosinophilic Gastrointestinal Disease (EGID) ƒomevi ɖeka ko . EGID ƒe nɔnɔme siawo ate ŋu akpɔ ŋusẽ ɖe wò nuɖuɖumeŋusẽ ƒe akpa vovovowo dzi . Esia fia be eosinophil lãmenugbagbevi siawo ate ŋu aƒo ƒu eye woahe abi vɛ le afisiafi tso nuɖuɖutome va ɖo dɔgboa me.

Ɣeaɖewoɣi ne eosinophils sɔ gbɔ akpa la, dɔléle siawo dometɔ siwo wu ɖeka ate ŋu adzɔ le ɣeyiɣi ɖeka me. EGID ƒomevi vevi ade ye li:

• Eosinophilic Colitis (EC): Esia gblẽa nu le wò dɔgbo gã (dɔgbo) ŋu .
• Eosinophilic Duodenitis: Esia gblẽa nu le wò dɔgbo suea ƒe akpa gbãtɔ ŋu .
• Eosinophilic Enteritis (EoN): Esia gblẽa nu le wò dɔgbo suea ŋu .
• Eosinophilic Esophagitis (EoE): Esiae nye EGID ƒomevi si bɔ wu. Egblẽa nu le wò nuɖuɖutome ŋu .
• Eosinophilic Gastritis (EG): Esia nye ƒomevi si ŋu míele nu ƒom tsoe, si gblẽa nu le dɔgboa ŋu.
• Eosinophilic Gastroenteritis (EGE): Esia gblẽa nu le dɔgbo kple dɔgbo sue ŋu koŋ.

Eosinophilic dɔléle ƒomevi bubuwo li siwo ate ŋu agblẽ nu le nuɖuɖumeŋusẽ ŋu, gake womebɔ vie o:

• Hypereosinophilic Syndrome: Esia ate ŋu agblẽ nu le ʋu kple ŋutinu ɖesiaɖe ŋu.
• Eosinophilic Granulomatosis with Polyangiitis (EGPA): Esia ate ŋu agblẽ nu le ŋutinu geɖe ŋu, siwo dome dzi hã le .

Aleke gbegbee eosinophilic gastritis bɔe?

Le nyateƒe me la, ɖɔktawo susui be eosinophilic gastritis nye dɔléle si mebɔ kura o . Eyae nye be menye dɔléle si dzea amesiame dzi o. Ke hã, eƒe dzesiwo – abe dɔgbo ƒe vevesese kple ʋuʋudedi ene – sɔ kple dɔléle bubu geɖe siwo bɔ la tɔ ŋutɔ. Eyata ɣeaɖewoɣi la, anɔ eme be woato eŋu (womekpɔe nyuie o) .

Nukae hea eosinophilic gastritis vɛ?

Eosinophilic gastritis va doa mo ɖaMenye ɣesiaɣie ɖɔktawo nya nusi tututu gbɔ wòtso o. Ema fia be esesẽ be woagblɔ be "esiae nye nusi gbɔ wòtso." Gake, zi geɖe la, wosusuna be nɔnɔmea dzɔna le esi míaƒe dɔlélenutsiŋutete wɔa nu wògbɔa eme ɖe nuɖuɖu aɖewo ŋu (nuɖuɖu ƒe nulɔdɔ) . Ele abe míaƒe ŋutilã ƒe ametakpɔnu si dze eya ŋutɔ ƒe dɔgbo dzi vodadatɔe ene.

Nukae nye eosinophilic gastritis ƒe dzesiwo?

Zi geɖe la, eosinophilic gastritis ƒe dzesiwo mesẽna o va ɖo esiwo le titina. Esia fia be ɖewohĩ ame aɖewo mase veve boo o, evɔ ame bubuwo ya ase veve vie. Dzesi siwo bɔ wue nye:

• Ƒodo ƒe vevesese alo ascites (sese le eɖokui me abe ƒodoa vuvu ene) .
• Aɖuɖɔtoe ( ʋuʋudedi) .
• Nuɖuɖu sesẽ ( nuɖuɖu ƒe dzodzro ) alo nu mimi sesẽ (dysphagia) .
• Ðeɖiteameŋu ƒe seselelãme ɣesiaɣi (Ðɖiteameŋu) .
• Dzimeve (dzobibi si sena le eɖokui me abe ɖe wòtso akɔta ene) .
• Ʋusɔgbɔdɔ , si fia be ʋumenugbagbevi dzĩ siwo le lãmesẽ me dzi ɖena kpɔtɔna (esia hã ate ŋu ana ɖeɖi nate ame ŋu eye wòazu ɣie) .
• Aɖuɖɔtoe kple ʋuʋudedi
• Ðevi suewo ƒe lolo dzi ɖeɖe kpɔtɔ alo tsitsi nyuie o

Ne dzesi siawo dometɔ ɖeka alo esi wu nenema le ŋuwò la, mègasusu be EG ye o. Esiawo ate ŋu anye dɔgbo ƒe dɔléle bubuwo hã ƒe dzesiwo. Eyata ele vevie be nàyi ɖɔkta gbɔ be yeanya nusi tututu gblẽ.

Aleke wowɔa dea dzesi eosinophilic gastritis (EG)?

Abe alesi míegblɔe va yi ene la, eosinophilic gastritis ate ŋu axɔ ɣeyiɣi aɖe hafi woakpɔe elabena eƒe dzesiwo bɔ ale gbegbe. Ðewohĩ èyi ɖɔkta geɖe gbɔ eye nèno atike geɖe.

Zi geɖe la, wodea dzesi esia to:

1. Ʋudodokpɔ: Wowɔa ʋu ƒe xexlẽme blibo (CBC) tsɔ léa ŋku ɖe eosinophils ƒe agbɔsɔsɔ si sɔ gbɔ wu esi sɔ ŋu hã.

2. Endoscopy: Le dodokpɔ sia me la, wotsɔa mɔ̃ tsɛ aɖe si me fotoɖemɔ̃ sue aɖe kpe ɖo la toa nu me eye wodoa nuɖuɖutome, dɔgbo, kple dɔgbo suea ƒe akpa gbãtɔ kpɔ. Woate ŋu alé ŋku ɖe dɔgboa ƒe gliwo ŋu be wovuvu, wobiã, eye abi suesuesuewo le wo ŋu hã.

3. Biopsy: Le endoscopy me la, woɖea lãkusi suesuesuewo (biopsies) tso dɔgboa ƒe gli me. Emegbe wodoa lãmenugbagbevi siawo kpɔna le nusuekpɔmɔ̃ me le nudokpɔƒe be woakpɔ eosinophil agbɔsɔsɔme si le wo me. Ne eosinophils sɔ gbɔ wu alesi wòle dzɔdzɔmee la, ate ŋu anye EG.

Ɣeaɖewoɣi la, ne eosinophil siawo siwo sɔ gbɔ la mele dɔgboa ƒe gli ƒe akpa si le etame o, ke boŋ wole ƒuƒoƒo siwo goglo wu me la, ate ŋu asesẽ be woakpɔ wo to lãmenugbagbeviwo ƒe dɔwɔwɔ edziedzi me. Ne edzɔ alea la, ate ŋu axɔ ɣeyiɣi didi hafi woate ŋu anya dɔlélea.

Be nànya EG la, wò ɖɔkta awɔ nu siwo gbɔna:

• Woado wò ŋutilã kpɔ .
• Woabia nya tso wò atikewɔwɔ ŋutinya ŋu (dɔléle siwo nèkpɔ va yi, ƒome ƒe dɔlélewo, atike siwo nèno, kple bubuawo).
• Woaɖe gbe be woado ʋu kpɔ, si akpe ɖe ame ŋu be woakpɔe ɖa be nu siwo mesɔ o hã le eme hã eye woaɖe dɔléle bubuwo ɖa.

Dodokpɔ bubu siwo kpena ɖe ame ŋu wòkpɔa EG

Dodokpɔ bubu siwo wò ɖɔkta ate ŋu abia tso wo si dometɔ aɖewoe nye:

• Nulɔdɔ dodokpɔ: Esia ate ŋu akpe ɖe ŋuwò nàde dzesi nusiwo nana nulɔdɔ le nuɖuɖu siwo ate ŋu anɔ wò eosinophils dzim ɖe edzi. Le kpɔɖeŋu me, ate ŋu akpe ɖe ŋuwò nànya ne nuɖuɖu aɖewo melɔ̃a nu le ŋuwò o. Nusiwo nulɔdɔ siawo nye nyanya ate ŋu akpe ɖe ŋuwò nàfia mɔ wò dɔlélea didi kple edada.

Ðe atike blibo aɖe li na eosinophilic gastritis (EG)a?

Nya sia nye nya si ame geɖe biana. Ne míagblɔe tututu la, fifia la, womekpɔ atike blibo aɖeke na eosinophilic gastritis o. Eyae nye be womate ŋu atsɔ atikekui ɖeka ko adae tegbee o.

Gake mègatsi dzi o! Atikewo kple tɔtrɔ le nuɖuɖu ŋu ate ŋu akpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ. Ne èwɔ ɖe wò atikewɔwɔ ŋuti mɔfiamewo dzi nyuie la, àte ŋu anɔ agbe si me dzo le, si me lãmesẽ le.

Ðe eosinophilic gastritis (EG) ate ŋu ade ame ƒe agbe afɔku mea?

Zi geɖe la, menye dɔléle si ate ŋu ade ame ƒe agbe afɔku me si hiã be woawɔ atike na ame kpata o. Gake ne wokpɔe kaba ahadae la, ate ŋu axe mɔ ɖe kuxi sesẽwo abe nunyuimakpɔɖu ene nu . Esia le vevie ŋutɔ na vidzĩwo kple ɖevi suewo, elabena nunyiame le vevie na woƒe tsitsi.

Aleke wodaa eosinophilic gastritis (EG)e?

Ðɔktawo daa eosinophilic gastritis koŋ kple nuɖuɖu ƒe tɔtrɔ kple atikewo. Dɔdamɔnu siawo ƒe taɖodzinue nye be woada nusi gbɔ wòtso (zi geɖe la, nulɔdɔ) eye woaɖu dzesiawo dzi. EG ƒe atikewɔwɔ si nàna anɔ te ɖe wò dzesiwo kple wò nɔnɔmea ƒe sesẽ dzi.

Ðewohĩ wò ɖɔkta aɖo aɖaŋu na wò be nàtrɔ asi le nuɖuɖu ŋu be nàƒo asa na nuɖuɖu ƒe nulɔdɔ siwo hea eosinophilic gastritis ƒe dzesiwo vɛ. Esiawo ate ŋu anye:

• Nuɖuɖu si woatsɔ aɖee ɖa: Le esia me la, èɖea nuɖuɖu aɖewo siwo nèsusu be woate ŋu ahe nulɔdɔ vɛ (e.g., notsi, soya, azi, lu, atikutsetse, ƒumelãwo) ɖa keŋkeŋ le wò nuɖuɖu me hena ɣeyiɣi aɖe. Emegbe, ègbugbɔa wo ɖe go ɖekaɖeka be nàkpɔ nuɖuɖu siwo hea kuxia vɛ.
• Nuɖuɖu veviwo:Esia nye mɔnu si to vovo vie. Le nuɖuɖu si woɖuna edziedzi teƒe la, wozãa tsi tɔxɛ aɖe si me nunyiame veviwo abe amino acid ene le tsɔ naa nunyiame. Atike sia mebɔ kura le nulɔdɔ ƒe afɔkua me o.

Ne EG ƒe dzesiwo le viwòa ŋu la, ahiã be nàtrɔ notsi ƒomevi si nènae (e.g., notsi si me nuléle mele o ). Le go aɖewo me la, ahiã be ɖeviwo kple ame tsitsiwo hã nano iron-tikewo ne ʋusɔgbɔdɔ le wo ŋu.

Àte ŋu axɔ atikewo abe esiawo ene hã:

• Corticosteroids (e.g., prednisone, budesonide): Wona esiawo be woatsɔ aɖe dɔdzẽ si le dɔgboa me dzi akpɔtɔ. Zi geɖe la, wonaa wo hena ɣeyiɣi kpui aɖe.
• Dɔlélenutsiŋutete ƒe atikewo (e.g. azathioprine): Wozãa esiawo tsɔ ɖea dɔlélenutsiŋutete ƒe dɔwɔwɔ fũu akpa dzi kpɔtɔna. Wotsɔa wo naa amesiwo mewɔ nu nyuie ɖe corticosteroid ɖeɖeko ŋu o, alo amesiwo mate ŋu ayi edzi anɔ corticosteroid nom o.

Ðe woate ŋu aɖe afɔku si le eosinophilic gastritis (EG) xɔxɔ me dzi akpɔtɔa?

Ne àte ŋu aɖe afɔku si le eme be nàxɔ eosinophilic gastritis dzi akpɔtɔ la nɔ te ɖe nɔnɔme si gbɔ wòtso dzi. Abe alesi míenyae ene la, nulɔdɔe nye nusi gbɔ eosinophil ƒe agbɔsɔsɔ si dzina ɖe edzi tsona wu.

Nuɖuɖu ƒe tɔtrɔ kple ne ehiã la, atikewo zazã ate ŋu akpe ɖe ŋuwò nàxe mɔ ɖe wò dɔlélenutsiŋutete ƒe nulɔdɔwo nu alo aɖu wo dzi. Le goawo katã me la, nuɖuɖu kple agbenɔnɔ si naa lãmesẽ ate ŋu aɖe dɔléle ƒe afɔku bliboa dzi akpɔtɔ. Ne nulɔdɔ le ŋuwò alo ne EG le wò ƒomea me la, anyo be nàƒo nu tso eŋu na wò ɖɔkta.

Nukae nye eosinophilic gastritis (EG) ƒe mɔkpɔkpɔ?

Le ame akpa gãtɔ gome la, zi geɖe la, eosinophilic gastritis ƒe mɔkpɔkpɔ nyo. Ema fia be àte ŋu anɔ agbe kplii nyuie. Gake ele vevie be míaɖo ŋku edzi be esi wònye dɔléle si nɔa anyi didi ta la, dɔnɔwo ate ŋu akpɔ dɔlélea ƒe ʋuʋu , alo ɣeyiɣi aɖewo ƒe dɔléle si nu mesẽ o.

Wò ɖɔkta awɔ dɔ kpli wò le wò agbemeŋkekewo katã me be wòakpe ɖe ŋuwò nàkpɔ eosinophilic gastritis gbɔ eye wòaɖe wò dzesiwo dzi akpɔtɔ. Ahiã be woawɔ dɔlékuiwutikewo kple ŋutilã ƒe akpa aɖewo ɖeɖe na wò edziedzi be woalé ŋku ɖe wò nɔnɔmea ŋu. Kpɔkpɔ sia ana wò ɖɔkta natrɔ asi le wò atikewɔwɔ ŋu, ne ehiã, be wòaxe mɔ ɖe kuxiwo nu na wò alo viwòa.

Nu vevitɔe nye be nàwɔ ɖe wò ɖɔkta ƒe mɔfiamewo dzi nyuie eye nàyi wò ɣeyiɣi siwo woɖo ɖi na wò la ɖe game dzi. Esia ana nàkpɔ egbɔ be wokpɔ beléle na wò ɖe game dzi.

Ðe eosinophilic gastritis (EG) kpɔa ŋusẽ ɖe nye agbenɔnɔ dzia?

Alesi EG kpɔa ŋusẽ ɖe wò agbenɔnɔ dzii la nɔ te ɖe wò dzesiawo ƒe sesẽme, nɔnɔme bubu siwo gbɔ wòtso, kple atikewɔwɔ ƒe dzidzedzekpɔkpɔ dzi. Zi geɖe la, ne eosinophilic gastritis le ŋuwò la, efia be ele be nàtrɔ asi le wò nuɖuɖu ŋu be nàƒo asa na nuɖuɖu ƒe nulɔdɔ, eye ɖewohĩ ahiã be nàno atike hã.

Le ame geɖe gome la, tɔtrɔ le woƒe nuɖuɖu ŋu ate ŋu anye kuxi le ŋutilã kple susu siaa me. Tsɔe be màte ŋu aɖu nuɖuɖu siwo nèlɔ̃na wu la dometɔ aɖewo o. Ate ŋu asesẽ be nàtia nuɖuɖu nyuitɔ ne èle tsa ɖim kple xɔ̃wòwo. Ðoɖowɔwɔ ɖe nuɖuɖu kple hadomewɔnawo ŋu ate ŋu asesẽ le gɔmedzedzea me.

Gake ne èwɔ ɖe atikewɔwɔ ŋuti mɔfiamewo dzi eye nèxɔ kpekpeɖeŋu ne èhiãe (le kpɔɖeŋu me, tso nuɖuɖuŋutinunyala gbɔ) la, àte ŋu anɔ lãmesẽ me ahanɔ dɔ dzi.

Ɣekaɣie wòle be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo le eosinophilic gastritis (EG) ŋu?

Ne dzesiwo abe dɔgbo ƒe vevesese atraɖii, ʋuʋudedi, nuɖuɖu ƒe dzodzro, alo ne edze abe wò dzesiwo le sesẽm ɖe edzi ene le ŋuwò la, bu eosinophilic gastritis ŋu eye nàdi atikewɔlawo ƒe aɖaŋuɖoɖo. Ðo dze kple wò ɖɔkta gaglãa tso wò dzesiwo kple alesi wole nu wɔm ɖe nuɖuɖu ƒe tɔtrɔ alo atikewo ŋu. Wò ɖɔkta ate ŋu aɖo wò ɖe dɔgboŋutinunyala gbɔ .

Nusiwo dzi wòle be míaɖo ŋkui tso esia me (Take-Home Message) .

Enyo, eyata mina míaɖo ŋku esia dzi abe nusi ŋu míeƒo nu tsoe egbea tso eosinophilic gastritis (EG) ŋu ƒe kpukpui ene:

• EG nye dɔléle si mebɔ o, si nɔa anyi didi, si gblẽa nu le wò dɔgbo ŋu.
• Susu vevitɔ si tae nye be ʋumenugbagbevi ɣi ƒomevi aɖe si woyɔna be eosinophils ƒoa ƒu ɖe dɔgboa me eye wòhea dɔdzẽ vɛ.
• Zi geɖe la, edo ƒome kple nulɔdɔwo .
• Esi wònye be dzesiawo (dɔgbo ƒe veve, lãmetutudɔ, aɖuɖɔtoe, nuɖuɖu ƒe dzodzro) sɔ kple dɔléle bubu siwo bɔ ta la, ate ŋu axɔ ɣeyiɣi aɖe hafi woaɖo kpe dɔlélea dzi.
• Endoscopy kple biopsy ye nye mɔnu vevitɔ siwo wozãna tsɔ dia dɔlélea.
• Togbɔ be womate ŋu adae bliboe o hã la, woate ŋu aɖe dzesiawo dzi akpɔtɔ ŋutɔ ne wozã atike alo tɔtrɔ le nuɖuɖu ŋu (vevietɔ ne woɖe nusiwo nana ame ƒe ŋutilã mewɔa dɔ nyuie o ɖa).
• Wò ɖɔkta awɔ dɔ kpli wò kplikplikpli be wòakpe ɖe ŋuwò nàkpɔ viɖe geɖe tso wò atikewɔwɔ me eye wòana wò agbenɔnɔ nanyo ɖe edzi.

Eya ta, ne dzesi siawo le ŋuwò la, mègavɔ̃ be yeaƒo nu tso wo ŋu na ɖɔkta o. Nusi tututu gblẽ la didi kple atike nyuitɔ xɔxɔ nye nu nyuitɔ kekeake si nàte ŋu awɔ na wò lãmesẽ.

` Eosinophilic Gastritis, Eosinophilic Gastritis, Dɔgbo ƒe dɔléle, Dɔgbo ƒe vevesese, Nulɔdɔ, Endoscopy, Nuɖuɖu, Eosinophils