Ðe dɔgbo me dɔdzẽ le wò ƒomea mea? Va, mina míaƒo nu tso domenyiŋusẽfianu ƒe nɔnɔme sia (Familial Adenomatous Polyposis - FAP) ŋu!

Ðe dɔgbo me kansa dze ame aɖe dzi le wò ƒomea me, ɖewohĩ le eƒe ɖevime? Alo ɖe ɖɔkta aɖe gblɔ na wò be tsitsi suesuesuewo (polyps) le wò dɔgbo me tsɔ kpe ɖe dɔgbo me kuxiwo ŋua? Èɖase nu sia tɔgbe alo mèse nya sia tɔgbe o, ate ŋu anɔ vevie ŋutɔ be nànya nɔnɔme sia si woyɔna be `FAP` si ŋu míele nu ƒom tsoe egbea. Elabena togbɔ be mebɔ vie o hã la, ne wokpɔe dze sii kaba la, ate ŋu aɖe wò tso kuxi gã geɖe me.

Nukae nye FAP le nya bɔbɔewo me?

Kpuie ko la, Familial Adenomatous Polyposis, alo FAP kpuie, nye domenyiŋusẽfianu ƒe nɔnɔme si nana nu suesuesue gbogbo aɖewo (polyps) siwo woyɔna be adenomas, siwo ate ŋu azu kansa, dzɔna le wò dɔgbo me eye ɣeaɖewoɣi le wò dɔgbo me.

Bu eŋu kpɔ, ame aɖewo xɔa dɔdzẽ siawo dometɔ ɖeka alo eve le woƒe dɔgbo me ne wole tsitsim. Ema sɔ. Gake le amesi ŋu `FAP` le gome la, zi geɖe la, dɔdzẽ siawo wu alafa ɖeka, ɣeaɖewoɣi akpe geɖe , gake wodzea tsitsi gɔme le woƒe ɖevime ŋutɔ, ɖewohĩ woƒe ƒe ewo xɔxɔ. Eyata mɔnukpɔkpɔ si li be dɔdzẽ siawo dometɔ ɖeka natrɔ azu kansa (`dɔdzẽ si le dɔgboa me`), si fia be afɔku si le eme le eƒe agbemeŋkekewo katã me la lolo ŋutɔ .

Be woaɖu afɔku sia dzi la, zi geɖe la, ɖɔktawo ɖoa aɖaŋu be woawɔ dɔ na ame aɖe atsɔ aɖe dɔgboa bliboa ɖa (total colectomy) . Ɣeaɖewoɣi la, woɖea aɖuɖɔtoe hã ɖa (proctocolectomy). Esia le alea elabena le FAP me la, dɔdzẽ siawo tsina kabakaba akpa be woate ŋu aɖu wo dzi to wo ɖeɖe ɖekaɖeka me. Le nyateƒe me la, ne womewɔ dɔ sia o la, kansa axɔ amesiwo ŋu FAP le dometɔ geɖe le woƒe ƒe titina .

Amesiwo ŋu FAP le ate ŋu axɔ dɔdzẽ ƒomevi bubuwo, menye le dɔgboa me ɖeɖeko o, ke le teƒe bubuwo hã, abe ŋutigbalẽ, lãkusi falɛfalɛ, aɖu, kple ƒuwo ene. Ne woɖe dɔgboa ɖa vɔ gɔ̃ hã la, ahiã be nàyi edzi anɔ dodokpɔ wɔm na wò be dɔdzẽ bubu siawo hã le ŋuwò, eye ahiã be nàwɔ dɔ na wò hã.

Afɔku kae le kansa xɔxɔ me na amesiwo ŋu FAP le?

Ne womewɔ atike na amesi ŋu FAP le o la, mɔnukpɔkpɔ si ade 100% kloe be wòaxɔ dɔdzẽ le dɔgboa me. Azɔ hã, kansa ate ŋu adze ame dzi kaba eye wòaxɔ ɖevi wu ame bubuwo. Ne wonya be dɔlélea le ƒomea me tɔ aɖe ŋu la, ele be woawɔ dɔ na ɖevi siwo le ƒome mawo me ƒe sia ƒe tso ƒe 10 xɔxɔ dzi .

Tsɔ kpe ɖe dɔgbo me kansa ŋu la, amesiwo ŋu FAP le la le afɔku me be woaxɔ kansa ƒomevi bubuwo:

• Kansa le dɔgbo sue ƒe akpa si le etame (`Duodenal cancer`) - abe 8% ene
• Papillary thyroid cancer - abe 2% ene .
• Dɔdzẽ si le dɔgboa me - abe 2% ene .
• Aklã me kansa si woyɔna be ``Hepatoblastoma`` (vevietɔ le ɖeviwo me) - abe 1.5% ene
• Dɔgbo me dɔdzẽ - abe 1% ene .
• Ahɔhɔ̃ kple aklã me dɔdzẽ - mede 1% o .

Ðe FAP ƒomevi vovovowo lia?

Ẽ, `FAP` ƒomevi vevi aɖe kple ƒomevi sue bubu geɖewo li tsɔ kpe ɖe ema ŋu.

• "Classic" FAP: Esia ƒe dzesi enye adenoma siwo wu 100 ƒe anyinɔnɔ le dɔgboa me.
• "Attenuated" FAP (AFAP): Esia nye ƒomevi sue si mesẽ vie o. Aɖuɖɔtoe siwo ade 20 va ɖo 100 le dɔgboa me.
• Gardner ƒe dɔléle: Abe `FAP` si wonya nyuie ene la, dɔdzẽ siwo wu 100 le dɔgboa me. Tsɔ kpe ɖe eŋu la, dɔdzẽ ƒomevi bubuwo dona le ŋutilãa ƒe akpa bubuwo.
• Turcot syndrome: Kansa ƒe dɔdzẽ aɖe dona le ahɔhɔ̃a me kpe ɖe dɔdzẽ geɖe siwo le dɔgboa me ŋu.

Aleke gbegbee woyɔa nɔnɔme sia be FAP?

FAP nye nɔnɔme si mebɔ kura o . Edzea ame ɖeka le ame 8,000 ɖesiaɖe me. FAP nye dɔgbo me dɔdzẽwo katã ƒe 0.5% lɔƒo. Dɔlékui ƒomevi suewo abe AFAP, Gardner ƒe dɔléle, kple Turcotte ƒe dɔléle ene mebɔ wu gɔ̃ hã o.

Vovototo kae le FAP kple Lynch ƒe dɔlélea dome?

Lynch ƒe dɔlélea nye domenyiŋusẽfianu bubu si nana be dɔgbo me kansa kple kansa bubuwo xɔxɔ ƒe afɔkua dzina ɖe edzi. Wogayɔa Lynch ƒe dɔlélea be HNPCC (domenyiŋusẽ ƒe nonpolyposis colorectal cancer syndrome). Abe alesi ŋkɔa ɖee fia ene la, esia mefia kokoko be dɔgbo me dɔdzẽ gbogbo aɖewo dona o .

Ame siwo ŋu Lynch ƒe dɔlélea le ate ŋu axɔ kansa ne dɔdzẽ ɖeka alo esi wu nenema le dɔgboa me gɔ̃ hã. Azɔ hã, dɔdzẽ kple kansa dona megbe vie wu le FAP me, eye afɔkua dzi ɖena kpɔtɔna vie. Domenyiŋusẽfianu ƒe tɔtrɔ vovovowo gbɔe nɔnɔme eve siawo tsona .

Nukae nye FAP ƒe dzesiwo? Aleke míewɔna dea dzesii?

Le FAP me la, dɔgbo me polyps dzea wɔwɔ gɔme kaba ŋutɔ wu le amehawo katã dome, zi geɖe le ƒewuiwo me . Ðewohĩ polyp siawo mahe dzesi aɖeke vɛ o vaseɖe esime wololo afɔkutɔe. Gake ne wowɔ dɔ na wò le dɔgboa me la, wò ɖɔkta ate ŋu ake ɖe wo ŋu.

Ame siwo ŋu `FAP` le ate ŋu akpɔ polyp alafa alo akpe geɖe le woƒe dɔgbo me . Ame siwo ŋu `AFAP` le la ƒe 20 ya teti.Esi wònye be polyps la sɔ gbɔ wu eye wòtsina kabakaba le `FAP` me ta la, woate ŋu ahe dzesiwo vɛ wu polyps. Dzesiawo dometɔ aɖewoe nye:

• Ʋu si dona le dɔgboa me
• Dɔmetɔtrɔ
• Ƒodo me vevesese atraɖii

Dzesi siwo ɖɔktawo ate ŋu ade dzesii le gota gome ate ŋu anɔ amesiwo ŋu FAP le ŋu ɣeaɖewoɣi:

• Dermatofibromas: Ka siwo le abe abi ene siwo le ŋutigbalẽa te.
• Epidermal cysts: Keratin yɔ fũu, siwo le dzogoe ene me siwo le ŋutigbalẽa te.
• Osteomas: Dɔdzẽ siwo menye kansa o siwo dzɔna le ƒuwo me. Wokpɔa wo wu le aɖu alo taɖu me.
• Aɖu bubuwo alo aɖu siwo ŋu ŋusẽ le:Woate ŋu akpɔ esiawo le aɖuawo ƒe X-ray me.
• Retinal pigment epithelium (CHRPE) ƒe dzidziɖedzi fũu akpa si wodzina: Woate ŋu akpɔ esiawo le ŋkumekpɔkpɔ me. Gake zi geɖe la, womehea ŋku ƒe kuxiwo vɛ o.

Ƒe nenie FAP ƒe dzesiwo dzea egɔme zi geɖe?

Le FAP me la, zi geɖe la, dɔgbo ƒe tsitsi dzea egɔme le ƒe 16 lɔƒo. Le AFAP me la, ate ŋu adze egɔme emegbe vie. Ne dziwòlawo kple ɖɔktawo nya be èle afɔku me na dɔlélea la, woate ŋu adze dodokpɔ gɔme na wò le ƒe 10 xɔxɔ vɔ megbe. Ne mèwɔe o la, woate ŋu akpɔe be dɔlélea le ŋuwò le wò dzesiwo ta.

Nuka koŋue hea FAP vɛ?

Nusi koŋ gbɔ FAP tsonae nye domenyiŋusẽfianu ƒe tɔtrɔ . Woyɔa domenyiŋusẽfianu sia be adenomatous polyposis coli (APC) domenyiŋusẽfianu . Wogayɔnɛ be domenyiŋusẽfianu si tea dɔdzẽ nu. Esia fia be domenyiŋusẽfianu sia xea mɔ na lãmenugbagbeviwo be woagatsi le wo ɖokui si o eye woagawɔ dɔdzẽ o. Ne domenyiŋusẽfianu ƒe tɔtrɔ aɖe dzɔ la, domenyiŋusẽfianu sia ƒe dɔwɔwɔ me gblẽna.

Domenyiŋusẽfianu ƒe tɔtrɔ si hea FAP vɛ nye dɔlékuiwo ƒe tɔtrɔ. Esia fia be menye nusi dzɔna le agbe me o, ke boŋ nusi dzɔna le fufɔɣi . Esia nye nusi wotsɔ tso dzidzime yi dzidzime. Ne domenyiŋusẽfianu ƒe tɔtrɔ sia le dziwòlawo dometɔ ɖeka ŋu la, mɔnukpɔkpɔ 50% le asiwò be nànyie ƒe dome. Gake tɔtrɔ siawo ƒe 30% lɔƒo nye yeyewo (nutɔtrɔ gbãtɔwo), si fia be womenyi wo dome o . Eyata dɔnɔ siwo wokpɔ be FAP le wo ŋu la dometɔ siwo ade 30% ate ŋu anye be dɔlélea ƒe ƒome ŋutinya aɖeke mele wo si o.

Nukawoe nye kuxi siwo ate ŋu ado tso FAP me?

Kuxi vevitɔ kekeake si gbɔ wòle be woakpɔ le FAP me enye dɔgbo me dɔdzẽ . Amekoko be woaɖe wò dɔgbo (colectomy) ate ŋu aɖe afɔku sia dzi akpɔtɔ ŋutɔ. Gake agbenɔnɔ dɔgbo manɔmee ate ŋu akpɔ ŋusẽ aɖewo ɖe wò agbe dzi elabena alesi nètoa aɖuɖɔ me trɔna. Ðewohĩ ahiã be nàzã ileostomy kotoku alo ileal kotoku ɖe dɔgboa teƒe.

Esi wònye be domenyiŋusẽfianu ƒe tɔtrɔ si hea FAP vɛ le lãmenugbagbevi ɖesiaɖe me le wò ŋutilã me ta la, dɔdzẽ ate ŋu ado mo ɖa le wò ŋutilã ƒe akpa sia akpa . Dɔdzẽ bubuwo hã ate ŋu ado le dɔgboa godo, eye woate ŋu azu kansa ɣeaɖewoɣi. Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ dodokpɔ ƒe ɖoɖo aɖe atsɔ adi dɔdzẽ siawo ƒomevi:

• Duodenal/periampullary ƒe ʋuʋudediwo:Esiawo dzɔna le wò dɔgbo suea ƒe akpa si le etame (duodenum), alo afisi ʋumenugbagbeviɣimɔ̃ alo dɔgbo ƒe mɔ̃a va kpena ɖe dɔgbo suea ŋu le. Amesiame kloe si ŋu FAP le la tua nusiawo ɖo. Ame ʋɛ aɖewo ate ŋu axɔ dɔdzẽ le aɖuɖɔtoe me, aɖuɖɔtoe me kansa, dɔdzẽ si le dɔgboa me le ʋuka me, alo dɔdzẽ le ʋuka me.
• Dɔgbo me ʋusɔgbɔdɔ: Ame siwo ŋu FAP le la dometɔ siwo ade 90% xɔa dɔgbo me dɔdzẽ, gake wo dometɔ 1% koe va zua kansa.
• Desmoid tumors: Esiawo nye dɔdzẽ siwo menye kansa o siwo dzɔna le kadodoŋusẽ me. Wodzɔna le amesiwo ŋu FAP le ƒe 15% lɔƒo me. Togbɔ be menye kansae wonye o hã la, woate ŋu ahe lãmesẽkuxi sesẽwo vɛ ɣeaɖewoɣi (anɔ abe 5%) eye woaku gɔ̃ hã. Woate ŋu awɔ adã ŋutɔ, akaka ɖe xɔ siwo te ɖe wo ŋu me, eye woazi ʋukawo, ŋutinuwo, kple lãmekawo dzi alo axe mɔ na wo. Wo ɖeɖe ɖa sesẽ eye woate ŋu agbugbɔ wo adze.
• Papillary thyroid cancer: Thyroid cancer sia ƒomevi dzɔna le amesiwo ŋu FAP le ƒe abe 2% ene me. Afɔku mele eŋu boo o eye zi geɖe la, woate ŋu adae.
• Aklã me dɔdzẽ: Afɔku sue aɖe koe le ɖevi siwo ŋu FAP le ŋu be woaxɔ aklãdɔ si mebɔ o si woyɔna be hepatoblastoma.
• Medulloblastoma: Esia nye ahɔhɔ̃mekansa. Ate ŋu adzɔ kple Turcot ƒe dɔléle, si do ƒome kple FAP. Le FAP gɔ̃ hã gome la, ƒã ŋutɔ.
• Aɖuɖɔtoe me tsiwo: Ne womeɖe wò dɔgbo kpe ɖe wò dɔgbo ŋu o la, ke èle afɔku me be dɔgbo me ʋukawo nadze dziwò, eyata ahiã be woado wò dɔgboa kpɔ le wò agbemeŋkekewo katã me.

Aleke nàwɔ anya kple kakaɖedzi be FAP le ŋuwò?

Ne èdi be yeanya nenye be APC domenyiŋusẽfianu ƒe tɔtrɔ ƒe domee nènyi la, àte ŋu anya to domenyiŋusẽfianu dodokpɔ wɔwɔ me . Domenyiŋusẽfianu ƒe dodokpɔ xɔa wò DNA (abe ʋu alo aɖuɖɔ ene) ƒe kpɔɖeŋu eye wòdia domenyiŋusẽfianu ƒe tɔtrɔ aɖewo koŋ. Ne domenyiŋusẽfianu ƒe tɔtrɔa le ŋuwò la, afɔɖeɖe si kplɔe ɖoe nye be nàwɔ dɔgbomekpɔmɔ̃ atsɔ akpɔe ɖa be adenomas hã le ŋuwò.

Wokpɔa FAP ne polyp 100 ya teti (20 ne AFAP) li eye APC domenyiŋusẽfianu ƒe tɔtrɔ le eme . Menye FAP koe nye domenyiŋusẽfianu si hea adenomatous polyps vɛ o. MUTYH-si do ƒome kple polyposis hã nye nɔnɔme ma tɔgbe, gake domenyiŋusẽfianu bubu si woyɔna be MUTYH ƒe tɔtrɔ gbɔe wòtso.

Nukae nye atikewɔwɔ ƒe ɖoɖo si wowɔ na amesi ŋu FAP le?

FAP ƒe atikewɔwɔ ƒe ɖoɖoa lɔ ŋkuléle ɖe ame ŋu le eƒe agbemeŋkekewo katã me kple amekoko si wòle be woawɔ ɖe eme ɖe eme.Le gɔmedzedzea me la, ne polyps (alo AFAP) ʋɛ aɖewo le ŋuwò la, wò ɖɔkta ate ŋu aɖe wo ɖekaɖeka le dɔgbo me dodokpɔ (polypectomy) me. Ne polyp-awo lolo ŋutɔ alo wozu kansa la, ate ŋu ahiã be woawɔ dɔ nɛ.

Amekoko

Ame akpa gãtɔ siwo ŋu FAP si wonya nyuie le la ahiã be woaɖe ʋumenugbagbeviɣidɔ bliboa le woƒe ƒe blaeveawo ƒe nuwuwu alo ƒe blaetɔ̃awo ƒe gɔmedzedze . Wò ɖɔkta anɔ te ɖe afɔku tɔxɛ siwo le ŋuwò dzi atso nya me le ɣeyiɣi si woawɔ dɔ na wò ŋu. Aƒo nu na wò hã tso colectomy ƒomevi vovovo siwo nàte ŋu awɔ ŋu.

Ne woɖe wò dɔgbo la, dometsotso aɖe nɔa wò dɔgbo sue kple dɔgbo (alo dɔgbo) dome. Ɣeaɖewoɣi la, amekola ate ŋu agbugbɔ nugbɔ eve siawo aƒo ƒu. Emegbe àte ŋu ana aɖuɖɔtoe nato wò dɔgbo me abe alesi nèwɔnɛ ɖaa ene. Ne ema mate ŋu adzɔ o la, woawɔ ‘ostomy’, si nye ʋuʋu yeye le wò ƒodo me be wò aɖuɖɔ nado.

Dzodzro

Wò atikewɔlawo ƒe ƒuƒoƒoa aɖo aɖaŋu na wò le zi nenie wòle be nàwɔ dodokpɔ siwo me nàdo dɔdzẽ ƒomevi vovovowo kpɔ le ŋu, le wò ŋutɔ wò afɔkuwo nu. Le FAP si wonya nyuie gome la, wokafui be woawɔ dɔgbomekpɔkpɔ ƒe sia ƒe tso ƒe 10 xɔxɔ vaseɖe esime woaɖe dɔgboa ɖa . Le AFAP gome la, ele be woadze dodokpɔ gɔme ƒe sia ƒe, adze egɔme tso ƒe 20 xɔxɔ dzi.

Le wò colectomy megbe la, ele be nàyi edzi awɔ sigmoidoscopy dodokpɔwo, siwo doa wò GI tract ƒe akpa si le ete. Ne wò dɔgbo ƒe akpa aɖe susɔ la, ele be nàna woadoe kpɔ ɣleti 6 va ɖo 12 ɖesiaɖe. Ne woɖe wò dɔgbo eye wotsɔ ileal pouch ɖɔ li la, ele be nàna woadoe kpɔ ƒe 1 va ɖo 4 ɖesiaɖe.

Dodokpɔ bubu siwo ŋu wowɔ ɖoɖo ɖo ate ŋu anye:

• Upper endoscopy: Esia sɔ kple colonoscopy, gake wowɔa esia le wò nuɖuɖumeŋusẽ ƒe akpa si le etame. Wotsɔa endoscope toa wò ŋɔti me yia wò dɔgbo kple wò dɔgbo sue (duodenum) ƒe akpa si le etame be woatsɔ akpɔe ɖa be polyps hã le eme hã. Ne woli la, wò ɖɔkta ate ŋu aɖe wo ɖa le ɣeyiɣi ma ke me kple dɔdamɔnua.
• Ultrasound dodokpɔwo hena thyroid alo aklã me dɔdzẽ.
• CT scan (kɔmpiuta tomography scan) alo MRI (magnetic resonance imaging) dodokpɔwo hena desmoid tumors.

Ðe woate ŋu axe mɔ ɖe FAP nua?

Domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo be nàse afɔku si le FAP ƒe nɔnɔmea tsɔtsɔ yi na viwòwo me gɔmeAte ŋu akpe ɖe ŋuwò. Nuƒoƒo tso afɔku siawo ŋu ate ŋu akpe ɖe ŋuwò nàwɔ ɖoɖo ɖe wò ƒomea ŋu. Zi geɖe la, manya wɔ be woaxe mɔ na domenyiŋusẽfianu ƒe tɔtrɔ be wòagadzɔ le fufɔɣi o, gake ɖoɖowɔwɔ ɖe ƒome ŋu ƒe tiatia vovovo aɖewo li siwo ŋu nàte ŋu abu.

Nukae nye ame si ŋu FAP le ƒe agbenɔƒe?

Ne womewɔ atike nɛ o la, ame ƒe agbenɔƒe le mama dedie nu anɔ abe ƒe 42 ene . Gake ne wokpɔ egbɔ nyuie eye wowɔ atike na wò nyuie la, àte ŋu anɔ agbe si sɔ . Ne woɖe wò dɔgboa ɖa vɔ la, wò afɔku gãtɔ tso nuɖuɖumeŋusẽ ƒe kansa bubuwo kple ‘desmoid’ dɔdzẽ siwo me kuxiwo le wu gbɔ. Esiawo mebɔ kura wu dɔgbo me dɔdzẽ o.

Ne nɔnɔme sia le ŋunye la, nukae wòle be makpɔ mɔ na?

Ne wokpɔe be FAP le ŋuwò la, àte ŋu akpɔ mɔ be woado ye kpɔ le yeƒe agbe me katã eye ɖewohĩ woawɔ dɔ na ye zi geɖe atsɔ aɖe dɔdzẽawo ɖa . Dɔdzẽ siwo dona le wò dɔgboa godo la mezua kansa boo o wu polyps siwo le wò dɔgbo me. Togbɔ be desmoid tumors menye kansa o hã la, woate ŋu anye fuɖename sue aɖe alo fuɖename gã aɖe ɣeaɖewoɣi.

Àte ŋu akpɔ mɔ be woaɖe colectomy bliboa le yeƒe agbe ƒe gɔmedzedze . Le ema megbe la, woate ŋu agbugbɔ wò dɔgbowo aƒo ƒu, alo woate ŋu awɔ ileal pouch alo ostomy na wò. Tiatia siawo dometɔ ɖesiaɖe ƒe afɔku le kuxi tɔxɛ aɖewo me. Gake àte ŋu anɔ agbe didi si me lãmesẽ le kokoko le colectomy megbe.

Enye nusi sɔ be nàlé blanui ahatsi dzimaɖi ne èse be domenyiŋusẽfianu ƒe dɔléle aɖe le ye ŋu si abia be woakpɔ ye gbɔ le yeƒe agbemeŋkekewo katã me. Gake ne ènya nya ko la, àte ŋu aɖe afɔ aɖewo atsɔ akpɔ wò kansa ƒe afɔkua gbɔ . Togbɔ be amekoko le wò etsɔme godoo hã la, ɖɔktawo adze agbagba be yewoana wòanɔ bɔbɔe alesi yewoate ŋui.

Woate ŋu awɔ dɔ na ame geɖe to dɔgboa me atsɔ aɖe dɔgboa ɖa, si wowɔna to lãɖeɖe suesuesuewo me eye wòhayana kabakaba . Ðewohĩ ahiã be woawɔ dɔ na amesiwo si ileal pouch le zi geɖe, gake mlɔeba la, woate ŋu azã nugododeƒea abe tsã ene.

Nu vevitɔ kekeake siwo dzi wòle be míaɖo ŋkui tso nusiwo me míedzro me (Take-Home Message) .

Enyo, eyata, tso nusi míeƒo nu tso `FAP` ŋu la, nu vevitɔ kekeake siwo dzi wòle be nàɖo ŋkui lae nye esi:

• FAP nye domenyiŋusẽfianu ƒe nɔnɔme si woate ŋu atsɔ ayi dzidzimewo me.
• Esia nana be polyp alafa alo akpe geɖe dzɔna le dɔgboa me, si ate ŋu azu kansa.
• Ne womewɔ atike nɛ o la, afɔku si le dɔgboa me kansa xɔxɔ me lolo ŋutɔ .
• Ele vevie ŋutɔ be woadze dɔgbome dodokpɔwo wɔwɔ gɔme tso ɖevime ke (ƒe 10-12) .
• Atikewɔwɔ vevitɔe nye amekoko be woaɖe dɔgboa ɖa (colectomy) .
• Ne woɖe dɔgboa ɖa vɔ gɔ̃ hã la, ehiã be woado ame ƒe agbemeŋkekewo katã kpɔ be dɔdzẽ siwo le dodom le ŋutilãa ƒe akpa bubuwo hã.
• Togbɔ be esia nye agbemeŋkekewo katã ƒe nɔnɔme si ŋu wòle be woakpɔ egbɔ hã la, ne wowɔ atike na ame nyuie eye wodoe kpɔ hã la, anya wɔ be woanɔ agbe si sɔ, si me lãmesẽ le .

Ne dzesi siawo dometɔ aɖe le ŋuwò alo wò ƒomea me tɔ aɖe ŋu, alo ne èdi be yeanya nu geɖe tso esia ŋu la, di atikewɔlawo ƒe aɖaŋuɖoɖo godoo . Nyanya kaba kple afɔɖeɖe kabae nye nu vevitɔwo kekeake.

` FAP, Ƒome ƒe Adenomatous Polyposis, Domenyiŋusẽfianu ƒe Dɔlélewo, Dɔgbo me Polyps, Dɔgbo me Dɔdzẽ, APC Domenyiŋusẽfianu, Dɔgbomekpɔkpɔ, Dɔgbomeɖeɖe, Amekoko