Ðe nèsena le ɖokuiwò me hã be yeƒe afɔwo le ƒoƒom? Esia ate ŋu anye Lambert-Eaton Myasthenic Syndrome (LEMS) ƒe dɔléle!

Ðe wòsena le ɖokuiwò me ɣeaɖewoɣi be yeƒe afɔwo gbɔdzɔ, esesẽna na wò be nàfɔ tso zikpui dzi, ɖeɖi tea ŋuwò ne èlia atrakpuiwoa? Alo ɖe ɖeɖi te ŋuwò le dzesiwo abe ŋkume ƒe ʋuʋu, nu ƒe ƒuƒu, kple nukpɔkpɔ zi eve ene ta? Ðewohĩ esiawo menye ɖeɖiteameŋu ko o. Egbea míaƒo nu tso nɔnɔme aɖe si ɖewohĩ mèse nu tsoe o, gake edze ŋutɔ be nànya nu tso eŋu, Lambert-Eaton Myasthenic Syndrome, alo ``(LEMS)`` abe alesi míeyɔnae kpuie ene.

Nukae nye Lambert-Eaton ƒe dɔléle si nye Myasthenic Syndrome (LEMS)?

Kpuie ko la, Lambert-Eaton Myasthenic Syndrome (LEMS) nye dɔléle si tsoa dɔlélenutsiŋutete gbɔ. Fifia ɖewohĩ ànɔ nusi dɔléle si nye autoimmune disorder nye ŋu bum . Dɔlélenutsiŋutete le míaƒe ŋutilã me. Esiae kpɔa mía ta to avuwɔwɔ kple dɔlékui siwo hea dɔléle vɛ siwo tso egodo me. Ele abe asrafoha si le míaƒe dukɔa me ene. Gake ɣeaɖewoɣi la, dɔlélenutsiŋutete sia mewɔa dɔ nyuie o. Emegbe edzea mía ŋutɔwo ƒe lãmenugbagbevi siwo le lãmesẽ me dzi dzedze gɔme. Emae nye nusi dzɔna le LEMS me.

Le `(LEMS)` sia me la, míaƒe dɔlélenutsiŋutete dzea kadodo si le míaƒe lãmekawo kple lãmekawo dome dzi . Ne míagblɔe tututu la, woyɔa kadodo sia be `neuromuscular junction`. Ne kadodo sia gblẽ la, gbedasiwo ƒe kaka tso lãmekawo me yia lãmekawo gbɔ megblẽna o. Esiae nye esime lãmekawo ƒe gbɔdzɔgbɔdzɔ dzɔna.

Zi geɖe la, gbɔdzɔgbɔdzɔ sia dzea egɔme tso wò ata si le etame , gake vivivi la, ate ŋu akaka ɖe wò abɔwo, gbɔgbɔ, nu mimi, kple nuƒoƒo ƒe lãmekawo me.

Amekae ate ŋu axɔ `(LEMS)` sia wu?

Ƒuƒoƒo vevi eve li siwo wɔ `(LEMS)`.

1. Edo ƒome kple kansa: Kansa ƒomevi aɖe le amesiwo ŋu LEMS le dometɔ siwo ade 60% ŋu . Wo dometɔ si bɔ wue nye lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ . Nukutɔe la, ɣeaɖewoɣi la, LEMS ƒe dzesiwo te ŋu dzena ɣleti geɖe alo ƒe geɖe gɔ̃ hã hafi kansa la nadze egɔme. Ame siawo dometɔ akpa gãtɔ xɔ wu ƒe 60, ŋutsuwoe wonye, ​​eye wozã atamanuwo kpɔ.

2. Kansa aɖeke meli o: Womekpɔ kansa aɖeke le amesiwo ŋu LEMS le ƒe 40% mamlɛawo ŋu o. Zi geɖe la, wokpɔa dɔlélea le ame siawo ŋu ne woxɔ abe ƒe 35 ene eye wogakpɔnɛ le ƒe 60 lɔƒo.

LEMS nye dɔléle si mebɔ kura le ɖevi suewo dome o.

Ðe lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ (LEMS) koe do ƒome kple esia?

Ao, lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽe nye kansa ƒomevi si bɔ wu, gake kansa ƒomevi bubuwo hã ate ŋu ado ƒome kple LEMS. Kpɔɖeŋu aɖewoe nye ʋumenugbagbeviɣidɔ, thymoma, kple ʋumenugbagbeviɣidɔ. Esi wònye be LEMS ƒe dzesiwo ate ŋu adze hafi kansa ƒe dzesiwo nadze ta la, ele vevie be nàwɔ dodokpɔ nyuitɔwo atsɔ akpɔ kansa hã ne wò ɖɔkta kpɔe be LEMS le ŋuwò.

Ðe domenyiŋusẽfianu ƒe tɔtrɔ gbɔe LEMS tsona?

Dzɔdzɔmeŋutinunyalawo xɔe se be domenyiŋusẽfianu ƒe kadodo aɖe ate ŋu anɔ dɔléle siwo dɔlélenutsiŋutete hena vɛ le goawo katã me. Esi wònye be LEMS hã nye dɔléle si dɔlélenutsiŋutete wɔna ta la, ate ŋu adzɔ be domenyiŋusẽfianu hã kpɔa ŋusẽ ɖe edzi, gake womese esia gɔme bliboe haɖe o.

Aleke gbegbee `(LEMS)` bɔe?

LEMS nye dɔléle si mebɔ kura o . Wobu akɔnta be nɔnɔme sia gblẽa nu le ame siwo ade miliɔn 2.8 ŋu le xexeame katã. Le United States la, wogblɔ be ame siwo ade 400 ye xɔ LEMS. Togbɔ be womegblɔ ame agbɔsɔsɔme si sɔ pɛpɛpɛ le míaƒe dukɔa me o hã la, edze ƒã be nɔnɔme sia mebɔ o.

Nukae nye `(LEMS)` ƒe dzesiwo?

Mina míalé ŋku ɖe `(LEMS)` ƒe dzesiwo ŋu ɖekaɖeka. Menye dzesi siawo katã dzena le ɣeyiɣi ɖeka me le amesiame gome o, dzesi aɖewo ate ŋu adze do ŋgɔ, ɖewo ate ŋu adze emegbe.

• Lãmetsiwo ƒe gbɔdzɔgbɔdzɔ kple ɖeɖiteameŋu: vevietɔ le afɔ siwo le etame.
• Azɔlizɔzɔ sesẽ: Atrakpui lialia alo fɔfɔ tso zikpui dzi sesẽna.
• Lãmetsiwo ƒe vevesese alo lãmekawo ƒe sesẽ.
• Seselelãme be abɔ kple afɔwo le ʋuʋum.
• Ŋku ƒe ʋuʋudedi (ptosis): Esia ate ŋu adze abe alɔ̃dɔdɔ ene.
• Nu eve kpɔkpɔ zi ɖeka (diplopia).
• Nu kple ŋku ƒe ƒuƒu (xerostomia): aɖuɖɔtoe dzi ɖena kpɔtɔna, aɖatsi si dona le ŋkuwo me dzi ɖena kpɔtɔna.
• Miléle.
• Fifia dzi ɖe kpɔtɔ.
• Kpekpeme dzi ɖeɖe kpɔtɔ.
• Aɖuɖɔtoe sesẽ.
• Ŋutsuwo ƒe tsitretsitsi ƒe dɔmawɔmawɔ nyuie.
• Nuƒoƒo sesẽ (dysarthria) kple nu mimi sesẽ (dysphagia): Zi geɖe la, esiawo nyea dzesi siwo doa mo ɖa emegbe le dɔlélea me.
• Yagbɔgbɔ sesẽ (gbɔgbɔtsixe) kple gbɔgbɔtsixetsixe: Esia hã nye dzesi si mebɔ o, si nu sẽ, si ate ŋu adze le dɔlélea ƒe nuwuwu.

Vevietɔ: Ne dzesi siawo dometɔ ɖeka alo esi wu nenema le ŋuwò la, mègasusui be LEMS ye o. Gake ne dzesi siawo gakpɔtɔ li la, nunya anɔ eme be nàdi atikewɔlawo ƒe aɖaŋuɖoɖo.

Aleke LEMS dzena zi geɖe eye wòyia ŋgɔe?

Zi geɖe la , LEMS gblẽa nu le ata ƒe lãmekawo ŋu gbã . Emegbe ate ŋu agblẽ nu le abɔta ƒe lãmekawo, abɔ kple afɔ ƒe lãmekawo, lãmeka siwo kpena ɖe ame ŋu le nuƒoƒo kple nu mimi me, kpakple ŋku ƒe lãmekawo dzi.

Le dɔlélea ƒe gɔmedzedze la, ate ŋu asesẽ na wò be nàfɔ tso zikpui dzi, alia atrakpui alo togbɛwo, alo awɔ dɔ sesẽ si abia be nàzã wò afɔwo.

Zi geɖe la, dzesiawo dzena vivivi, le kwasiɖa ʋɛ aɖewo va ɖo ɣleti geɖe me . Gake ne LEMS si ŋu kansa le le ŋuwò la, dzesiawo ate ŋu adze egɔme kaba.

Nukae hea LEMS vɛ?

Abe alesi míeƒo nu tso eŋu va yi ene la, LEMS nye dɔléle si dɔlélenutsiŋutete hena vɛ . Esia fia be wò ŋutilã ŋutɔ ƒe ametakpɔnuwo (dɔlékuiwutikewo) dzea wò ŋutɔ wò lãmeka siwo le lãmesẽ me dzi. Le LEMS me la, dɔlékuiwutike siawo dzea teƒe si lãmekawo kple lãmekawo do go le, si nye ahɔhɔ̃mekawo ƒe kadodo. Etɔxɛe la, wodzea calcium-mɔ̃ siwo le afima dzi. Calcium-mɔ̃ siawo le vevie hafi lãmekawo ƒe gbedasiwo nate ŋu aɖo.

Bu eŋu abe domino siwo le fli me ene. Amedzidzedze sia dzea nudzɔdzɔ vovovowo gɔme:

1. Dɔlékuiwutikeawo blana ɖe calcium-mɔ̃ siwo le lãmekawo ƒe nuwuƒewo ŋu eye woxea mɔ na wo.

2. Ne woɖe calcium-mɔ̃wo dzi kpɔtɔ la, acetylcholine, si nye ahɔhɔ̃mekawo ƒe dɔwɔwɔ, si dona le lãme na ame dzi ɖena kpɔtɔna. Acetylcholine sia nye atike si hiã vevie na lãmekawo ƒe dɔwɔwɔ.

3. Ne acetylcholine mesɔ gbɔ o la, "gbedasi" siwo yina na lãmekawo metoa eme nyuie o. Ekema wò lãmekawo mate ŋu awɔ dɔ bliboe o.

4. Esia wɔe be lãmekaawo mewɔa dɔ nyuie o, si wɔnɛ be wogbɔdzɔna.

Alesi amesiwo ŋu lãmenugbagbevi suewo ƒe lãkusi me kansa le la xɔa LEMS enye si: Ne kansa le wò ŋutilã me la, dɔlékuiwutikewo xɔa dzesi be "yi aʋa." Gake le esi teƒe be dɔlékuiwutike siawo nadze kansa lãmenugbagbeviwo dzi (vevietɔ, calcium mɔ siwo le kansa lãmenugbagbeviwo ƒe anyime) la, wodzea calcium mɔ siwo le lãmekawo ƒe nuwuƒewo dzi vodadatɔe. Emegbe nudzɔdzɔwo ƒe kɔsɔkɔsɔ ma ke dzɔna.

Dzɔdzɔmeŋutinunyalawo xɔe se be nusi gbɔ LEMS tsona le amesiwo ŋu aɖuɖɔtoedɔdzẽ mele o ŋu nye dɔlélenutsiŋutete ƒe dɔmawɔmawɔ nyuie ko. Gake womenya nusitae wòdzɔna alea haɖe o.

Aleke woawɔ ade dzesi `(LEMS)`?

Afɔɖeɖe gbãtɔ si nàwɔ atsɔ anya LEMS ye nye be wò ɖɔkta nado wò kpɔ nyuie. Zi geɖe la, esia alɔ ahɔhɔ̃ŋutinunyala, alo ɖɔkta si bi ɖe lãmekawo kple lãmekawo ƒe dɔlélewo me ɖe eme. Dɔ sia ƒe akpa aɖee nye be nàbia nya tso wò dzesiwo, wò atikewɔwɔ ŋutinya, kple atike ɖesiaɖe si nèno ŋu. Wowɔa ahɔhɔ̃mekawo ŋuti dodokpɔ tsitotsito be woadi gbɔdzɔgbɔdzɔ ƒe nɔnɔmewo kple dzesi siwo sɔ kple LEMS.

Afɔɖeɖe si kplɔe ɖoe nye dodokpɔ. Dodokpɔwo na `(LEMS)` dometɔ aɖewoe nye:

• Ʋudodokpɔ: Esia ate ŋu akpɔe ɖa be dɔlékuiwutike siwo tsia tre ɖe calcium channel ŋu le wò ʋu me hã. Ame siwo ŋu LEMS le la dometɔ siwo ade 85% ƒe ʋu me dɔlékuiwutike siawo le.
• Electromyography (EMG): Dodokpɔ sia léa ŋku ɖe alesi wò lãmekawo kple lãmekawo le dɔ wɔm ɖekae nyuie ŋu. Le LEMS me la, nusiwo ŋu woke ɖo le EMG dodokpɔa me la le tẽ ŋutɔ, eyata ate ŋu akpe ɖe ame ŋu woaɖo kpe dɔlélea dzi.
• Aklã ƒe X-ray `(X-ray)` alo CT scan `(CT scan)` alo MRI scan `(MRI)` (le akɔta): Esi wònye be nɔnɔme aɖe si woyɔna be `(LEMS)` ate ŋu ado mo ɖa le amesiwo ŋu lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ le ŋu ta la, dodokpɔ siawo dia dzesi siwo fia be lãkusi me dɔdzẽ le wo ŋu.

LEMS ƒe dzesiwo ate ŋu adze egɔme tso ɣleti va ɖo ƒe ade hafi kansa nadze egɔme. Eyata ne wokpɔ LEMS vɔ la, ele be woado wò kansa kpɔ ɣleti etɔ̃ va ɖo ade ɖesiaɖe hena ƒe eve ya teti. Wò ɖɔkta aɖo aɖaŋu na wò be nàwɔ dodokpɔ ƒe ɖoɖowɔɖi si sɔ na wò.

Aleke wowɔa atike na LEMS?

Atikewɔwɔ vovovowo li na LEMS.

• Kansa si gbɔ wòtso dada: Ne LEMS do ƒome kple kansa aɖe, abe lãmenugbagbevi suewo ƒe lãkusi me kansa ene la, kansa ma dada ate ŋu aɖe LEMS ƒe dzesiwo hã dzi akpɔtɔ. Kansa dada ate ŋu anye atikewɔmɔnu, keklẽŋusẽdɔdamɔnu, kple/alo amekoko. Esia nɔ te ɖe kansa ƒomevi kple wò ɖɔkta ƒe aɖaŋuɖoɖowo dzi.
• Atike tɔxɛwo na (LEMS): Esiawo dometɔ aɖewoe nye atike siwo ɖea dzesiwo dzi kpɔtɔna kple atike siwo kpɔa dɔlélenutsiŋutete dzi.

Dɔlélea ƒe dzesiwo dada

• Amifampridine (Firdapse®), Guanidine: Atike siawo dzia lãmekawo ƒe ŋusẽ ɖe edzi. Wodzia ahɔhɔ̃mekawo ƒe dɔwɔwɔ si nye acetylcholine ƒe dodo ɖe edzi le ahɔhɔ̃mekawo ƒe ƒoƒoƒe, si wɔnɛ be dzesi siwo yia lãmekawo gbɔ la nyona ɖe edzi.
• Pyridostigmine (Pyridostigmine - Mestinon®): Pyridostigmine wɔa dɔ to mɔxexe ɖe acetylcholine ƒe gbagbã nu le ahɔhɔ̃mekawo ƒe ƒoƒo me. Esia hã dzia acetylcholine ƒe dzesiwo ɖe edzi eye wònaa lãmekawo ƒe ŋusẽ nyona ɖe edzi. Wotsɔa pyridostigmine kpena ɖe amifampridine ŋu ɣeaɖewoɣi be wòana lãmekawo nawɔ dɔ nyuie wu eye wòada LEMS ƒe dzesiwo abe nu ƒe ƒuƒu, ŋku ƒe ƒuƒu, dɔmeɖui, gbɔdɔdɔ ƒe dɔmawɔmawɔ nyuie, kple fifia si dzi ɖe kpɔtɔ ene. Gake pyridostigmine zazã na LEMS nye zazã si mele ŋkɔ me o, si fia be U.S. Nuɖuɖu Kple Atike Ŋuti Dɔwɔƒe (FDA) meda asi ɖe atike si woatsɔ awɔ dɔléle sia dzi o.

Dɔlélenutsiŋutete ƒe atikewɔwɔ

• Dɔlélenutsiŋutete ƒe atikewo:Atike siawo kpena ɖe ŋuwò be wò dɔlélenutsiŋutete ƒe "takpɔkpɔ" ƒe dɔwɔwɔ nu natɔ te alo kpɔa edzi. Wò ɖɔkta ate ŋu aŋlɔ atike siawo na wò ne atike bubuwo meɖu wò dzesiwo dzi o. Le kpɔɖeŋu me, woate ŋu ana atike aɖe si woyɔna be prednisone kple azathioprine alo cyclosporine alo manɔmee.
• Plasma exchange: Le dɔ sia wɔwɔ me la, mɔ̃ aɖe ɖea wò ʋu ƒe akpa si nye tsi (plasma) ɖa tso ʋumenugbagbeviawo gbɔ. Wò dɔlékuiwutikewo le ʋumenugbagbeviɣi sia me. Le wo kaklã megbe la, wogatsɔa ʋua dea wò ŋutilã me. Wò ɖɔkta ate ŋu abu atikewɔwɔ sia ŋu ne dzesi sesẽwo le ŋuwò eye nèhiã atikewɔwɔ kpata.
• Dɔlékuiwutikewo: Le ame aɖewo gome la, dɔlélenutsiŋutete ƒe atike si wozãna le agbɔsɔsɔ gã me ate ŋu akpe ɖe ame ŋu be dɔlélea nagagblẽ ɖe edzi o.

Ðe woate ŋu axe mɔ ɖe LEMS nua?

Womese nusi tututu gbɔ LEMS tsona gɔme bliboe haɖe o, eyata womenya ne mɔ aɖe li si dzi woato axe mɔ ɖe dɔlélea nu o.

Gake esi wònye be LEMS ate ŋu adze amesiwo ŋu aɖuɖɔtoedɔdzẽ le dzi ta la, àte ŋu akpe asi ɖe eŋu be woaxe mɔ ɖe aɖuɖɔtoemekansa nu to:

• Mègano atama o. Ne èzãa atamanuwo la, bia wò ɖɔkta be wòakpe ɖe ŋuwò nàdzudzɔ atamanono.
• Ƒo asa na dzudzɔ si wozãna tsã.
• Kpɔ wò aƒeme ɖa be radon gas hã le eme hã. Radon gas zazã ɣeyiɣi didi ate ŋu ana wò aɖuɖɔtoedɔléle ƒe afɔkua nadzi ɖe edzi.

Àte ŋu aɖe afɔ aɖewo hã be nàlé agbe nyui nɔnɔ me ɖe asi:

• Ƒo atikutsetse kple amagbe geɖe wu. Wɔ ɖe Mediterranea alo DASH nuɖuɖu dzi.
• Lé lolo si sɔ me ɖe asi.
• De kame abe alesi wò ɖɔkta ɖo aɖaŋu na wò ene.
• Dɔ alɔ̃ nyuie - zi geɖe la, gaƒoƒo adre va ɖo enyi.
• Ðe wò nuteɖeamedzi dzi kpɔtɔ. Nuteɖeamedzi ate ŋu ana dzesiawo nagagblẽ ɖe edzi.
• Ƒo asa na tsi dzodzoe tsilele. Dzoxɔxɔ ate ŋu ana LEMS ƒe dzesiwo nagagblẽ ɖe edzi.
• Kpɔ wò ɖɔkta edziedzi, eye nàna woanya enumake ne wò lãmesẽ trɔ alo ne dzesi yeyewo dze le ŋuwò.

Ðe woate ŋu ada LEMS keŋkeŋa?

Nublanuitɔe la, atike aɖeke meli na LEMS o. Wokpɔe be kansa si le ete si do ƒome kple LEMS dada nana LEMS ƒe dzesiwo nyona ɖe edzi. Dɔlélenutsiŋutete ƒe atikewo ate ŋu akpe ɖe ame ŋu wòaɖu dɔlélenutsiŋutete ƒe amedzidzedze dzi, eye atikewɔmɔnu aɖewo hã li siwo ate ŋu akpe ɖe ame ŋu woaɖe dzesiawo dzi akpɔtɔ to acetylcholine ƒe agbɔsɔsɔ si le lãmekawo ƒe nuwuwu dzi ɖeɖe kpɔtɔ kple lãmekawo ƒe ŋusẽ dodo ɖe ŋgɔ me.

Ne LEMS le ŋuwò si me kansa mele o la, àte ŋu akpɔ mɔ be yeanɔ agbe si sɔ. Ne LEMS kple kansa le ŋuwò la, wò dzesiwo ate ŋu anyo ɖe edzi le ɣeyiɣi aɖe megbe (togbɔ be menye keŋkeŋ o hã) ne wokpɔ kansa la hekpɔ egbɔ kaba.

Wò agbenɔnɔ ƒe nyonyome nɔ te ɖe wò dzesiawo ƒe sesẽ dzi koŋ.

Ɣekaɣie wòle be mate ɖe nye ɖɔkta ŋu ne `(LEMS)` le ŋunye?

Ne tɔtrɔ aɖe va wò lãmesẽ me, alo ne wò dzesiawo gagblẽ ɖe edzi la, te ɖe wò ɖɔkta ŋu ɣesiaɣi . Mègavɔ̃ o, mègatsi dzodzodzoe o. Ðɔktawo li be yewoakpe ɖe ŋuwò.

Vovototo kae le `(LEMS)` kple `(Myasthenia Gravis - MG)` dome?

Lambert-Eaton myasthenic syndrome (LEMS) kple myasthenia gravis (MG) hã ƒe dzesi aɖewo sɔ. Wo ame evea siaa nana lãmekawo gbɔdzɔna eye ɖeɖi tea wo ŋu.

Gake zi geɖe la, myasthenia gravis (MG) gblẽa nu le lãmeka siwo ƒo xlã wò ŋkuwo kple lãmeka siwo wozãna tsɔ mia nu ŋu gbã. Emegbe ate ŋu akpɔ ŋusẽ ɖe lãmeka siwo bɔ wu dzi, siwo dometɔ aɖewoe nye gbɔgbɔ ƒe lãmekawo kple abɔ kple afɔwo ƒe lãmekawo.

Zi geɖe la, LEMS dzea egɔme kple gbɔdzɔgbɔdzɔ le wò ata ƒe akpa si le etame, emegbe wòʋuna yia wò abɔwo gbɔ. LEMS ate ŋu ana wò ŋku ƒe lãmekawo hã nagbɔdzɔ, gake zi geɖe la, eƒe lãme fa wu myasthenia gravis (MG).

Le myasthenia gravis (MG) me la, gbɔgbɔtsixe ƒe lãmekawo (lãmeka siwo kpena ɖe ŋuwò nègbɔa ya) ƒe gbɔdzɔgbɔdzɔ vevie ate ŋu awu ame. Esia mebɔ le LEMS me o.

Zi geɖe la, amesiwo ŋu myasthenia gravis (MG) le meɖea autonomic nervous system ƒe dɔmawɔmawɔ nyuie ƒe dzesi geɖe fiana o (e.g., ŋkuwo ƒe ƒuƒu, nu ƒe ƒuƒu, dɔmeɖui, fifia dzi ɖeɖe kpɔtɔ, gbɔdɔdɔ ƒe dɔmawɔmawɔ nyuie). To vovo na ema la, zi geɖe la, nyatoƒoetoto siawo nɔa amesiwo ŋu LEMS le ŋu, eye dzesi siawo ate ŋu akpe ɖe ame ŋu ɣeaɖewoɣi be woade vovototo dɔléle eveawo dome.

Mlɔeba la, nusiwo dzi wòle be woaɖo ŋkui (Take-Home Message) .

Ðewohĩ èse egɔme fifia be Lambert-Eaton Myasthenic Syndrome (LEMS) nye dɔléle si dɔlélenutsiŋutete si wɔa dɔ fũu akpa hena vɛ. Wò lãmekawo meɖoa gbedasi siwo sɔ ɖe wò lãmekawo be "woaƒo ƒu" o. Nusi dona tso emee nye lãmekawo ƒe gbɔdzɔgbɔdzɔ kple dzesi bubuwo.

Ðo ŋku edzi be amesiwo ŋu LEMS le la dometɔ siwo ade 60% xɔa lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ. Ne LEMS le ŋuwò gake kansa mele ŋuwò o la, kpɔ egbɔ be mia kple wò ɖɔkta miado kansa kpɔ ɣleti ʋɛ aɖewo ɖesiaɖe hena ƒe eve ya teti le dɔlélea kpɔkpɔ vɔ megbe.

Dɔdamɔnu aɖewo li. Esiawo dometɔ aɖewoe nye kansa la dada ne ele eme, kpakple atike siwo nana lãmekawo ƒe lãmenugbagbeviwo kple lãmekawo dome kadodo nyona ɖe edzi nono. Dzeɖoɖo ƒe nyonyo ate ŋu ana lãmekawo ƒe ŋusẽ kple dzesi bubuwo nanyo ɖe edzi.

Mele mɔ kpɔm be nyatakaka sia aɖe vi na wò.Ðo ŋku edzi ɣesiaɣi be ne lãmesẽkuxi aɖe le ŋuwò la, anyo wu be nàƒo nu tso eŋu kple ɖɔkta si nya nu tso eŋu.

` Lambert-Eaton myasthenic syndrome, LEMS, autoimmune dɔlélewo, lãmekawo ƒe gbɔdzɔgbɔdzɔ, lãmenugbagbevi suewo ƒe lãkusi me dɔdzẽ, ahɔhɔ̃mekawo ƒe ƒoƒo, acetylcholine