Ðe dzesi siawo le ŋuwò hã? Mina míaƒo nu tso MALT Lymphoma ŋu!

Èse dɔléle wɔnuku aɖe si woyɔna be MALT Lymphoma ŋu nya kpɔa? Ðewohĩ menye nenemae o. Elabena ƒã vie, si fia be menye dɔléle si dzea amesiame dzi o. Gake enyo be míanya nu tso eŋu. Elabena esia hã nye kansa ƒomevi aɖe. Gake mègavɔ̃ o, ekaka blewu le ŋutilã me. Egbea, míaƒo nu tso eŋu tsitotsito, abe ɖe míele nu ƒom na mía xɔlɔ̃ aɖe ene.

Nukae nye MALT Lymphoma? Kpuie ko la,...

Enyo, MALT Lymphoma nye kansa ƒe hatsotso gãtɔ si woyɔna be `non-Hodgkin lymphoma` ƒe hatsotso sue aɖe. Ne míagblɔe bubui la, enye ʋumenugbagbeviɣidɔ ƒomevi siwo tsina blewu siwo woyɔna be `marginal zone lymphoma` la dometɔ ɖeka.

Zi geɖe la, dɔléle sia dzea ame siwo xɔ wu ƒe 65. Ebɔ ɖe ŋutsuwo hã me wu nyɔnuwo. Nu nyuitɔ kekeakee nye be atikewɔmɔnu siwo ate ŋu ada dɔléle sia le ɖɔktawo si. Eyae nye be woateŋu atsɔ dɔlélea ade ``remission`` , alo alɔ̃dɔdɔ ƒe nɔnɔme me. Ke hã, ele be míaɖo ŋku edzi be ɣeaɖewoɣi la, ate ŋu agadzɔ ake.

Nukawoe nye MALT Lymphoma ƒomeviwo?

MALT ʋumenugbagbeviɣidɔ ƒomevi vevi eve li:

1. Gastric MALT Lymphoma: Esia dzea egɔme tso wò dɔgbo me, si fia be le dɔgboa me. Dɔgbo ƒe akpa si le eme, si míeyɔna be `mucosa` , ye wòdzea egɔme tsoe. Zi geɖe la, ƒomevi sia nɔa afisi wòdze egɔme tsoe, gake ɣeaɖewoɣi la, ate ŋu akaka ɖe teƒe siwo mele dɔgboa godo o. Esiae nye MALT ʋumenugbagbeviɣidɔ ƒomevi si bɔ wu.

2. Non-gastric MALT Lymphoma: Esia ƒomevi ate ŋu akpɔ ŋusẽ ɖe lãkusi siwo le wò lãkusiwo, aɖuɖɔtoewo, lãkusi, kple ŋutigbalẽ me dzi . Ate ŋu akpɔ ŋusẽ ɖe lãkusi siwo ƒo xlã wò ŋkuwo abe aɖatsimɔ̃wo ene hã dzi .

Aleke gbegbee dɔléle sia bɔe?

Le nyateƒe me la, MALT lymphoma nye dɔléle si mebɔ kura o. Exɔa ʋumenugbagbeviɣidɔ siwo katã menye Hodgkin o ƒe 7% lɔƒo. Be míatsɔ nya ma ade nukpɔsusu nyuitɔ me la, Amerikatɔwo ƒe Kansa Habɔbɔ gblɔ be woakpɔ non-Hodgkin lymphoma le ame 80,550 ŋu le ƒe 2023 ɖeɖe dzaa me. Ne wotsɔe sɔ kple ame yeye 300,590 siwo xɔ no me dɔdzẽ. Eyata àte ŋu akpɔ alesi gbegbe esia mebɔ o.

Aleke gbegbee MALT Lymphoma kaka kabakabae?

Esia nye nya vevi aɖe. Dɔléle sia tsina blewu ŋutɔ le ŋutilã me. Le gɔmedzedzea me la, ɖewohĩ dzesi gã aɖeke manɔ eŋu o. Ɣeaɖewoɣi la, woke ɖe MALT lymphoma ŋu le vome esime wole dɔléle bubu dom kpɔ.

Nukae nye esia ƒe dzesiwo?

Dzesiawo toa vovo le afisi ʋumenugbagbeviɣidɔa le nu. Gake MALT ƒe ʋumenugbagbeviɣidɔwo katã dzea egɔme tso:Lãmetsiŋusẽ ƒe lãkusi (`mucosa`). Lãmetsi sia nye nusi ƒo xlã míaƒe ŋutilã ƒe ŋutinu aɖewo ƒe eme.

Gastric MALT Lymphoma ƒe dzesiwo

Dɔgbo gbɔe esia tsona, eye eƒe dzesiwo ate ŋu anye:

• Dzimeve kple nuɖuɖumaɖumaɖu: Abe dzimeve kple nuɖuɖumaɖumaɖu si mí katã míenya ene.
• Dɔgbo ƒe vevesese.
• Aɖuɖɔtoe kple ʋuʋudedi.
• Nuɖuɖua mevivina o.
• Be woanye ame tsɛ le susu aɖeke manɔmee.
• Ʋu si dona le dɔgboa me.

Dzesiwo le Non-gastric MALT Lymphoma ŋu

Esia ƒomevi ate ŋu agblẽ nu le ŋkuwo, lãkusiwo, aɖuɖɔtoewo, ŋutigbalẽ, kple lãkusi ŋu.

Ne ŋkuwo ŋue wògblẽ nu le:

• Ŋku ƒe ʋuʋudedi si le gegem ɖe anyi.
• Ŋkuwo ƒe bibi alo dɔdzẽ.
• Ŋkuwo ƒe vuvu ƒo xlãe.
• Nukpɔkpɔ eve.

Ne dɔlélea le lãkusiwo ŋu la:

• Yagbɔgbɔ sesẽ.
• Akɔtave.
• Kɔdzi alo kɔdziyiyi ʋu.

Ne aɖuɖɔtoewo ŋue wògblẽ nu le:

Woate ŋu akpɔ ʋuʋudedi:

• Toawo le ŋgɔgbe.
• Le asike te.
• Le nu me.

Ne ŋutigbalẽa gblẽ nu le eŋu la:

• Teƒe dzĩ, pink, alo aŋutiɖiɖi le ŋutigbalẽa ŋu.
• Ŋutilã ƒe ƒuƒoƒo.

Ne ʋumenugbagbeviɣidɔa gblẽ nu le eŋu la:

• Lãmetsiŋusẽ ƒe dɔmawɔmawɔ nyuie ƒe dzesiwo: Esiawo dometɔ aɖewoe nye ɖeɖiteameŋu si gbɔ eme, ŋutigbalẽ ƒe ƒuƒu, lolo si womenya o, alo vuvɔ ƒe seselelãme ƒe dzidziɖedzi.
• Kpe aɖe si le kɔ ƒe ŋgɔgbe.

Nukae hea MALT Lymphoma vɛ?

Nu vevi geɖe li siwo gbɔ dɔléle sia tsona, siwo dometɔ aɖewoe nye dɔlékui alo dɔlékuiwo ƒe dɔlélewo kple dɔlélenutsiŋutete ƒe dɔlélewo .

• Dɔlékuiwo kple dɔlékuiwo:
• Dɔlékui si nye `H. pylori` ye nye nu vevitɔ si gbɔ gastric MALT lymphoma tsona. `H. pylori` nye dɔlékui si hea dɔgbo kple abi vɛ le dɔgboa me.
• Dɔlékui bubuwo, abe `Achromobacter xylosoxidans`, `Campylobacter jejuni`, `Borrelia burgdorferi` kple `C. psitiaci`, hã kpɔe be edo ƒome kple MALT ʋumenugbagbeviɣidɔ ƒomevi eveawo siaa.
• Aklãdɔlékui C ate ŋu ado ƒome kple MALT ʋumenugbagbeviɣidɔ si le dɔgboa me kple esi menye dɔgbo me o siaa hã.

• Dɔlélenutsiŋutete ƒe dɔlélewo:
• `Hashimoto ƒe dɔléle` (nɔnɔme si gblẽa nu le lãkusi ŋu) kple `Sjögren ƒe dɔléle` (Sjögren ƒe dɔléle) .(Esia nana nuwo abe ŋkuwo kple nu ƒuna) ate ŋu ahe MALT ʋumenugbagbeviɣidɔ aɖewo siwo menye dɔgbo me o vɛ.

Nukawoe nye afɔku siwo ate ŋu ana woaxɔ MALT Lymphoma?

Ne ʋumenugbagbeviɣidɔ dze wò ƒomea me tɔ aɖe dzi la, àte ŋu adze afɔku hã be MALT ʋumenugbagbeviɣidɔ axɔ wò. Ke hã, esia mebɔ ɖe amesiame gome o.

Aleke wowɔna dea dzesi MALT Lymphoma?

Ðɔktawo wɔa dodokpɔ geɖe tsɔ dea dzesi dɔléle sia eye wokpɔa afisi wòkaka ɖo.

Ʋudodokpɔwo

Ðɔktawo ate ŋu awɔ ʋudodokpɔwo abe esiawo ene:

• `CBC (ʋu ƒe xexlẽme blibo):` léa ŋku ɖe lãmenugbagbevi ƒomevi siwo le ʋua me ŋu.
• `LDH (lactate dehydrogenase): Esia ateŋu adzi ɖe edzi le kansa aɖewo me.
• `CMP (comprehensive metabolic panel)` (comprehensive metabolic test): Eléa ŋku ɖe ŋutinuwo abe ayiku kple aklã ƒe dɔwɔwɔ ŋu.
• Aklãdɔléle C dodokpɔ.

Biopsy ƒe dɔwɔwɔ

Ðɔktawo ate ŋu awɔ biopsies abe esia ene:

• Ƒumeŋuɖui ŋuti numekuku: Be woakpɔe ɖa be kansa la kaka ɖe ƒumeŋuɖui me hã.
• Needle biopsy: Woɖea lãkusi sue aɖe tso ƒunukpeƒetetedɔ si ŋu ɖikeke le me hedoa wo kpɔna.

Ɣeaɖewoɣi la, ne wosusu be gastric MALT lymphoma la, woate ŋu aɖe ŋutilã ƒe akpa aɖe le upper endoscopy , si bia be woatsɔ fotoɖemɔ̃ sue aɖe ade nu me atsɔ ado dɔgboa kpɔ.

Nɔnɔmetatawo ɖeɖe ƒe dodokpɔwo

Dodokpɔ siawo kpena ɖe ame ŋu be woanya afisi ʋumenugbagbeviɣidɔa le kple afisi wòkaka ɖo (afɔɖeɖe):

• `Kɔmpiuta tomography (CT) ƒe fotoɖeɖewo`.
• `Positron ƒe dodo tomography (PET) ƒe fotoɖeɖewo`.

Nudokpɔƒe ƒe dodokpɔwo

Atikewɔwɔ me dɔléleŋutinunyalawo zãa dodokpɔwo abe esiawo ene tsɔ doa lãmenugbagbeviwo alo kansa lãmenugbagbeviwo kpɔna:

• `H. pylori test`: Woɖea biopsy sample be woatsɔ akpɔe ɖa be dɔlékui sia le eme hã.
• Flow cytometry: Dodokpɔ tɔxɛ aɖe si kpena ɖe ame ŋu wòdea dzesi lãmenugbagbeviwo ƒe nɔnɔme.

Kansa ƒe afɔɖeɖe ŋuti nyanya (na gastric MALT lymphoma) (Cancer staging) .

Ðɔktawo zãa kansa ƒe ɖoɖowɔwɔ ƒe mɔnuwo tsɔ wɔa ɖoɖo ɖe atikewɔwɔ ŋu eye wogblɔa nusi woakpɔ mɔ na le atikewɔwɔ vɔ megbe ɖi. Le gastric MALT lymphoma gome la, woate ŋu azã mɔnu siwo gbɔna la dometɔ ɖeka:

• Afɔɖeɖe I: Dɔgboa ƒe akpa si le eme koe kansa la le.
• Afɔɖeɖe II: Kansa la kaka ɖe ʋuka siwo te ɖe wo ŋu me, ʋuka siwo le didiƒe ʋĩ, alo ŋutinu kple lãkusi siwo te ɖe wo ŋu me.
• Afɔɖeɖe IV:Kansa la kaka ɖe ʋuka geɖe me, ƒumeŋuɖui, kple ƒumeŋuɖui la tame kple ete.
• Naneke meli si woyɔna be Afɔɖeɖe III na gastric MALT lymphoma o.

Aleke wodaa MALT Lymphoma ƒe dɔléleae?

Nu geɖe dzie atikewɔwɔ nɔ te ɖo, siwo dometɔ aɖewoe nye MALT ʋumenugbagbeviɣidɔ ƒe ƒomevi, nusi gbɔ wòtso, kple afisi dɔlélea le. Le kpɔɖeŋu me, numekuku aɖewo ɖee fia be woate ŋu atsɔ dɔlékuiwutikewo ada dɔgbo ƒe MALT ʋumenugbagbeviɣidɔ si le gɔmedzedzea me keŋkeŋ, vevietɔ ne H. pylori dɔlékui gbɔe wòtso.

Atikewɔwɔ ƒe tiatia ate ŋu anye:

• `Watchful waiting/active surveillance`: Ðɔktawo ateŋu akafu mɔnu sia na amesiwo ŋu MALT lymphoma ƒe gɔmedzedze le siwo mele dzesi aɖeke ɖem fia o. Esia fia be woalé ŋku ɖe dɔlélea ŋu atike aɖeke manɔmee.
• Dɔlékuiwutikewo: Dɔdamɔnu sia wua dɔlékui si nye H. pylori, si hea dɔgbo ƒe MALT ʋumenugbagbeviɣidɔ vɛ. Numekuku aɖewo ɖee fia be H. pylori wuwu ate ŋu ada dɔlélea gɔ̃ hã.
• Kekelidɔdada: Ðɔktawo ate ŋu azã keklẽŋusẽdɔdamɔnu atsɔ ada MALT ʋumenugbagbeviɣidɔ ƒomevi eveawo siaa.
• Monoclonal antibody therapy: Atikewɔwɔ sia ate ŋu akpe ɖe amesiwo ŋu gastric MALT lymphoma si mewɔa dɔ ɖe keklẽŋusẽdɔdamɔnu dzi o alo amesiwo ŋu non-gastric MALT lymphoma le ŋu.

Ðe woate ŋu ada MALT Lymphoma keŋkeŋa?

Ẽ, abe alesi míegblɔe va yi ene la, woate ŋu atsɔ dɔlékuiwutikewo ada dɔgbo ƒe MALT ʋumenugbagbeviɣidɔ si le eƒe gɔmedzedze, vevietɔ esi H. pylori hena vɛ. Le go bubuwo me la, atikewɔwɔ ateŋu atsɔ dɔlélea ade `remission` , si nye alɔ̃dɔdɔ ƒe nɔnɔme me. Ke hã, ate ŋu atrɔ ava (`recurring`).

Nukae nye dɔlélea ƒe ŋgɔdonya?

Ðewohĩ wò dzi adze eme ne èse nya sia. Ame siwo ŋu MALT lymphoma le ate ŋu anɔ agbe ƒe geɖe, ne dɔlélea gadze egɔme le atikewɔwɔ vɔ megbe gɔ̃ hã. Esia le alea elabena enye ƒomevi si tsina blewu.

Nukae nye agbetsitsi ƒe agbɔsɔsɔme?

Numekuku aɖe ɖee fia be amesiwo ŋu MALT ʋumenugbagbeviɣidɔ le dometɔ siwo ade 88% gakpɔtɔ le agbe le ƒe atɔ̃ megbe tso esime wokpɔ dɔlélea. Gake nenɔ susu me na wò be akɔntabubu siwo wotu ɖe ame bubuwo ƒe nuteƒekpɔkpɔwo kple nyatakaka siwo woƒo ƒu le ɣeyiɣi aɖe megbe dzi koe agbetsitsi ƒe agbɔsɔsɔme siawo nye. Wò nuteƒekpɔkpɔ ate ŋu ato vovo. Le nɔnɔme siawo me la, wò ɖɔktae nye ame nyuitɔ si ana nyatakaka wò.

Ðe woate ŋu axe mɔ ɖe MALT Lymphoma nua?

Le nyateƒe me la, atikewɔwɔ ŋuti numekulawo menya nusiwo katã nana dɔléle sia xɔa amewo me o. Numekuku aɖe ɖee fia nenemaNe woƒo asa na H. pylori dɔlékui xɔxɔ ate ŋu aɖe afɔku si le dɔgboa me MALT ʋumenugbagbeviɣidɔ xɔxɔ me dzi akpɔtɔ.

Aleke malé be na ɖokuinye?

Ame geɖe hiã atikewɔwɔ le woƒe agbemeŋkekewo katã me. Esia fia be woado wo kpɔ edziedzi akpɔe ɖa be dɔlélea gatrɔ gbɔ hã. Zi geɖe la, ahiã be woado wò kpɔ ahawɔ scan na wò ɣleti etɔ̃ va ɖo ade ɖesiaɖe vaseɖe ƒe atɔ̃. Le ema megbe la, ahiã be woado wò kpɔ zi ɖeka le ƒea me.

Ɣekaɣie wòle be makpɔ ɖɔkta?

Zi geɖe la, amesiwo ŋu MALT lymphoma le la yia woƒe ɖɔktawo gbɔ edziedzi. Gake yi ɖɔkta gbɔ enumake ne:

• Ne MALT Lymphoma le ŋuwò eye nède dzesi tɔtrɔ yeyewo (siwo ate ŋu anye dzesiwo) le wò ŋutilã me.
• Ne wole atike wɔm na wò eye wò dzesiwo gagblẽ ɖe edzi.
• Ne èle `remission` me, si fia be ne dɔlélea nyo ɖe edzi la, èle tɔtrɔwo kpɔm le alesi wòsena le eɖokui me ŋu, abe ɖe dɔlélea le `gbugbɔm` ene.

Nya kawoe wòle be mabia nye ɖɔkta?

Ne MALT Lymphoma le ŋuwò la, àte ŋu abia nya siawo wò ɖɔkta:

• MALT ʋumenugbagbeviɣidɔ ka ƒomevie le ŋunye?
• Afikae nye dɔlélea le?
• Ðe mehiã atikewɔwɔa?
• Ne mehiã atikewɔwɔ la, atikewɔwɔ kae nàkafu?
• Ðe dɔdamɔnu dodokpɔ aɖewo li siwo ŋu wòle be mabua?

Ðo ŋku edzi be: MALT Lymphoma nye kansa ƒomevi aɖe si mebɔ o si gblẽa nu le míaƒe ŋutinuwo kple ŋutilã ƒe akpa bubuwo ƒe lãkusi ŋu, si nye ʋumenugbagbeviɣidɔ si menye Hodgkin tɔ o ƒomevi aɖe. Etsina blewu, eyata zi geɖe la, mehea dzesi gã aɖeke vɛ o. Ðɔktawo ate ŋu adae, eye ɣeaɖewoɣi la, woadae. Gake dɔlélea ate ŋu atrɔ ava, eyata ate ŋu ahiã be woawɔ atike na ame geɖe wu. Ne dɔléle sia le ŋuwò la, ƒo nu kple wò ɖɔkta tso nusi nàkpɔ mɔ na ŋu.

Mlɔeba la, gbedasi si woatsɔ ayi aƒemee

Enyo, ɖeko magblɔ nu ʋɛ aɖewo siwo dzi wòle be nàɖo ŋkui tso nusiwo ŋu míeƒo nu tsoe me na wò:

• MALT Lymphoma nye kansa ƒomevi aɖe si tsina blewu. Mègavɔ̃ o, ke boŋ nɔ ŋudzɔ.
• Wole ƒomevi eve: dɔgbo (le dɔgbo me) kple esi menye dɔgbo o (le teƒe bubuwo).
• Dɔlékui siwo nye `H. pylori` nye nu vevi aɖe si hea dɔgbo ƒe dɔléle vɛ.
• Dzesiawo nɔ te ɖe afisi ʋumenugbagbeviɣidɔa le dzi, eye ɖewohĩ dzesi aɖeke manɔ eŋu le gɔmedzedzea me o.
• Atikewɔwɔ aɖewo li, eye ɣeaɖewoɣi la, woate ŋu adae keŋkeŋ, vevietɔ le dɔgbo me dɔdzẽ ƒe gɔmedzedze.
• Dɔlélea ate ŋu agadzɔ ne èyi ɖe eƒe tsɔtsɔke me, eyata ele be nàyi edzi anɔ atikewɔlawo ƒe dzikpɔkpɔ te.
• Ne ɖikeke alo nyabiase aɖewo le mewò la, mègavɔ̃ be yeaƒo nu kple wò ɖɔkta o. Emae nye nu nyuitɔ kekeake si nàwɔ.

Mele mɔ kpɔm be nyatakaka sia aɖe vi na wò. Nɔ lãmesẽ me!

` MALT ʋumenugbagbeviɣidɔ, ʋumenugbagbeviɣidɔ si menye Hodgkin o, kansa, dɔgbo MALT ʋumenugbagbeviɣidɔ, H. pylori, ʋumenugbagbeviɣidɔ ƒe dzesiwo, ʋumenugbagbeviɣidɔ ƒe atikewɔwɔ