Ðe wòdze abe viwò sue ƒe ta lolo wu vidzĩ bubuwo enea? Mina míaƒo nu tso (Megalencephaly) ŋu!

Ðewohĩ ède dzesii be viwò suea ƒe ta lolo vie wu vidzĩ bubu siwo nye eƒe ƒemetɔwo, alo? Ðewohĩ kposɔ kple taɖa siwo viwòa dona la le sue ale gbegbe be asesẽ be nàkpɔ woƒe lolome si sɔ na eƒe ƒexɔxɔ. Ðe esia nye nusi dzɔ le vome ko, alo ɖe wònye nusi ŋu wòle be míatsi dzi ɖo viea? Egbea míele nu ƒom tso nɔnɔme aɖe si woyɔna be ``Megalencephaly'', si woyɔna hã be ``Macencephaly'', si ateŋu anɔ vevie na wò le ɣeyiɣi sia tɔgbe me ŋu.

Eyata nukae nye ``Megalencephaly'' sia?

Kpuie ko la, ``Megalencephaly`` nye nɔnɔme si me viwòa ƒe ahɔhɔ̃ lolona le mɔ si mesɔ o nu . Zi geɖe la, esia nɔa anyi le vidzidzi me. Nusi dzɔna le afisiae nye be ahɔhɔ̃a ŋutɔ va nɔa kpekpem akpa. Eyae nye be ahɔhɔ̃a ƒe kpekpeme wu alesi wokpɔ mɔe le ɖevia ƒe ƒexɔxɔ kple eƒe ŋutilã ƒe lolome nu.

Esia ƒe dzesi gbãtɔwo dometɔ ɖeka ate ŋu anye ta gã si mebɔ o. Ðewohĩ viwòa mate ŋu ado kposɔ alo taɖa si sɔ ɖe eƒe ƒexɔxɔ nu o le esi wole sue akpa ta.

Ahɔhɔ̃ gã ƒe amesinɔnɔ ate ŋu akpɔ ŋusẽ ɖe ɖevi ƒe tsitsi dzi ɣeaɖewoɣi. Esia fia be woate ŋu akpɔ tsitsi ƒe megbetsitsi aɖewo. Le kpɔɖeŋu me, woate ŋu anɔ blewu wu alesi wokpɔ mɔe be woagblɔ woƒe nya gbãtɔwo, atso atam, alo azɔ azɔli.

Zi geɖe la, nɔnɔme sia si woyɔna be ``Megalencephaly`` dzɔna kpe ɖe atikewɔwɔ ƒe nɔnɔme bubuwo ŋu. Nusi koŋ gbɔ esia tsonae nye domenyiŋusẽfianu ƒe tɔtrɔ.

Nukae nye `(Megalencephaly)` ƒomevi veviwo?

Nɔnɔme sia ƒomevi vevi etɔ̃e li:

1. Tagbɔdɔléle Gbãtɔ: Wogayɔa esia be Benign Familial Megalencephaly alo Idiopathic Megalencephaly. Le go sia me la, ahɔhɔ̃ gã aɖe le ɖevia si, gake dzesi bubu aɖeke alo ahɔhɔ̃mekawo ƒe kuxi aɖeke mele eŋu o. Zi geɖe la, dzila ɖeka alo evea siaa ƒe ta ate ŋu akeke hã. Viwòa ƒe ta ate ŋu adzi ɖe edzi vivivi vaseɖe esime wòaxɔ abe ɣleti 18 ene, eye le ema megbe la, ate ŋu ali ke.

2. Metabolic Megalencephaly: Esia tsoa lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe vodada siwo wodzina, si nye domenyiŋusẽfianu ƒe ƒuƒoƒo aɖe si kpɔa ŋusẽ ɖe alesi míaƒe ŋutilã wɔa nuɖuɖui dzi.

3. Anatomic Megalencephaly: Domenyiŋusẽfianu ƒe tɔtrɔ si gblẽa nu le ɖevia ƒe lãmekawo ƒe tsitsi ŋu gbɔe esia ƒomevi tsona. Wobua esia be enye ahɔhɔ̃mekawo ƒe tsitsi ƒe dɔléle. Zi geɖe la, wobua nɔnɔme si woyɔna be Megalencephaly be enye dɔléle aɖe si le ame ƒomevi sia me ƒe dzesi.

Anɔ eme be ɖɔkta si le viwòa dam la anɔ te ɖe ahɔhɔ̃a ƒe akpa si (hemisphere) lolo wu alesi wokpɔ mɔe dzi anya megalencephaly ƒomevi si le eŋu:

• Akpa Ðeka ƒe Tagbɔdɔléle (Hemimegalencephaly / Akpa Ðeka ƒe Tagbɔdɔléle):Nusi dzɔna le esia mee nye be ahɔhɔ̃a ƒe akpa ɖeka koe lolona wu evelia.
• Bilateral Megalencephaly: Esia gblẽa nu le ahɔhɔ̃a ƒe akpa eveawo siaa ŋu. Akpa eve gɔmee nye "afã eveawo siaa."

Nukae nye nɔnɔme sia ƒe dzesiwo?

Megalencephaly ƒe dzesiwo ate ŋu ato vovo. Ðewohĩ dzesi aɖeke manɔ ɖevi aɖewo ŋu o eye ɖeko woƒe ta lolo. Gake ɖevi aɖewo ate ŋu akpɔ dzesiwo abe:

• Tsitsi ƒe megbetsitsi: Heheɖemegbe le nuwo abe nuƒoƒo kple azɔlizɔzɔ ene me, abe alesi míegblɔe xoxo ene.
• Epilepsy (`Seizures` / `Epilepsy`): Esia fia nɔnɔme siwo le abe alɔ̃madɔmadɔ ene.
• Ahɔhɔ̃mekawo ƒe kuxiwo: Ahɔhɔ̃ kple aklã ƒe dɔwɔwɔ si mesɔ o.

Ɣeaɖewoɣi la, megalencephaly ate ŋu adzɔ le eɖokui si dzesi aɖeke manɔmee. Ɣebubuɣiwo la, ate ŋu adzɔ kpe ɖe ahɔhɔ̃mekawo ƒe kuxi bubuwo kple vidzidzi ƒe gbɔdzɔgbɔdzɔwo ŋu. Le nɔnɔme siawo me la, dɔléle alo nɔnɔme bubu ma gbɔe megalencephaly tsona.

Dzesi bubu siwo woate ŋu akpɔe nye:

• Ta gã alo esi mesɔ o.
• Susu ƒe nuwɔametɔnyenye.
• Ʋuʋu kple dadasɔ sesẽ.
• Lãmetsiwo ƒe sesẽ alo gbɔdzɔgbɔdzɔ.
• Tɔtrɔ siwo va le nukpɔkpɔ me.

Eyata nukae hea esia vɛ?

Alesi viwòa ƒe ahɔhɔ̃menugbagbeviwo tsinae ƒe gbegblẽ gbɔe megalencephaly tsona. Wosusu be domenyiŋusẽfianu ƒe tɔtrɔ koŋ gbɔe wòtso .

Woyɔa alesi ahɔhɔ̃meka yeyewo, alo lãmekawo ƒe lãmenugbagbeviwo, dzɔna le míaƒe ŋutilã me be `(Ahɔhɔ̃mekawo ƒe dzidziɖedzi)`. Zi geɖe la, míaƒe ŋutilã ɖɔa ɖoɖo sia ɖo, eye wòwɔa lãmenugbagbeviwo le agbɔsɔsɔ si sɔ pɛpɛpɛ me, le ɣeyiɣi si sɔ pɛpɛpɛ me. Gake le ɖevi si ŋu `(Megalencephaly) le gome la, wowɔa lãmenugbagbevi siawo wògbɔa eme, alo womeyia teƒe siwo sɔ o. Esia ate ŋu adzɔ ne ɖevia le tsitsim le vidzidɔa me alo abe atikewɔwɔ ƒe nɔnɔme bubu aɖe ƒe akpa aɖe ene.

Dɔléle bubu kawoe ate ŋu ado mo ɖa kple nɔnɔme sia?

Megalencephaly ate ŋu adzɔ kple dɔléle kple dzesi bubu geɖewo, le eƒe ƒomevi kple domenyiŋusẽfianu si me wòtso nu.

Dɔléle siwo do ƒome kple Anatomic Megalencephaly:

Zi geɖe la, wobua esia ƒomevi be enye nɔnɔme siwo gbɔna ƒe dzesi:

• `(Akɔntabubu ƒe dɔléle)`
• `(Bannayan-Riley-Ruvalcaba ƒe dɔléle)`
• `(Greig ƒe tagbɔdɔléle ƒe dɔléle)`
• `(Opitz–Kaveggia ƒe dɔléle)`
• `(Pretzel ƒe dɔléle)`
• `(Simpson-Golabi-Behmel ƒe dɔléle)`
• `(Sotos ƒe dɔléle)`
• `(Awutɔ ƒe dɔléle)`

Dɔléle siwo do ƒome kple Metabolic Megalencephaly:

Megalencephaly ate ŋu anɔ viwòa ŋu tsɔ kpe ɖe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe vodada siwo wodzina ŋu. Esiawo nye kuxi siwo le alesi ŋutilãa gbãa nuɖuɖui hezãa ŋusẽe ŋu. Esiawo ate ŋu anye nɔnɔmewo abe:

• Nusiwo mesɔ o le organic acids (`Organic acidurias`) me.
• Tagbɔdɔléle siwo tsoa lãmenugbagbeviwo me, abe Canavan dɔléle kple Alexander ƒe dɔléle ene.
• Lysosomal nudzraɖoƒe dɔlélewo, abe Tay-Sachs dɔléle kple Sandhoff dɔléle ene.

Amekae le afɔku me wu le esia ta?

Nɔnɔme aɖe si woyɔna be ``Megalencephaly'' ateŋu adze ɖevi ɖesiaɖe dzi. Gake ebɔ ɖe ŋutsuviwo me wu . Le go aɖewo me la, ateŋu anye domenyiŋusẽfianu ƒe domenyinyi tso wò ƒomea gbɔ, alo ateŋu adzɔ ``ɣeaɖewoɣi'' le susu aɖeke si medze o ta.

Aleke wokpɔa dɔléle sia dzea sii? (`Dɔléle ƒe dzesi`) .

Viwò ƒe ɖɔkta ate ŋu asusu be megalencephaly le viwòa dodokpɔ kple dodokpɔ ʋɛ aɖewo wɔwɔ vɔ megbe. Ne ɖɔkta le viwòa dom kpɔ la, atsɔ dzidzenu adzidze viwòa ƒe ta ƒe gotagome. Emegbe, woatsɔ dzidzenu ma asɔ kple dzidzenu siwo sɔ na ɖevia ƒe ƒexɔxɔ, ŋutsu alo nyɔnu nyenye, kple eƒe kɔkɔme.

Tsɔ kpe ɖe eŋu la, ɖɔkta ate ŋu aɖe gbe hã be woado nɔnɔmetatawo kpɔ, abe MRI ene, be woatsɔ alé ŋku ɖe ɖevia ƒe ahɔhɔ̃ ŋu ahakpɔ nusiwo mesɔ o.

Bu eŋu ale: MRI le abe ahɔhɔ̃a ƒe akpa si le eme ƒe fotoɖeɖe ene. Enaa ɖɔktaa kpɔa ahɔhɔ̃a ƒe nɔnɔme, eƒe lolome, kple tɔtrɔ ɖesiaɖe si ava eme la nyuie.

Ne wò ɖɔkta susui be dɔléle bubu aɖe le eŋu kpe ɖe megalencephaly ŋu la, ahiã be woawɔ dodokpɔ bubuwo atsɔ aɖo kpe dɔlélea dzi. Dodokpɔ bubu siawo ate ŋu anye:

• Ʋudodokpɔwo.
• Aɖuɖɔtoe dodokpɔwo.
• Domenyiŋusẽfianu dodokpɔwo.

Ɣekaɣie wokpɔa nɔnɔme sia zi geɖe?

Ɣeaɖewoɣi la, dzilawo kple ɖɔktawo dea dzesii be vidzĩ ƒe ta lolona le edzidzi megbe teti alo le ɣleti ʋɛ gbãtɔwo me. Nɔnɔmea (megalencephaly) ate ŋu adze egɔme hã ne vidzĩa le tsitsim, zi geɖe le vidzĩme kple ɖevimenɔɣi.

Ɣeaɖewoɣi la, ne wole ultrasound scan wɔm le fufɔɣi gɔ̃ hã la, woate ŋu ade dzesi unilateral megalencephaly (ahɔhɔ̃a ƒe akpa ɖeka ko ƒe lolome).

Nukawoe nye atike siwo wozãna na esia?

Fifia la, womekpɔ atike aɖeke na megalencephaly o. Gake atikewɔmɔnu aɖewo li siwo ate ŋu akpe ɖe viwòa ŋu wòaɖu eƒe dzesiwo dzi. Le viwòa ƒe dzesiwo nu la, ɖɔkta ate ŋu aɖo aɖaŋu na wò be:

• Ne alɔ̃madɔmadɔ li la, wonaa atike siwo wua alɔ̃madɔmadɔ alo ne ehiã la , wowɔa dɔ na asrãdɔ .
• Gomekpɔkpɔ le atikewɔwɔwo abe ŋku ƒe dɔdamɔnu, ŋutilãmedɔdada, dɔwɔwɔ ƒe atikewɔwɔ, alo nuƒoƒo ƒe atikewɔwɔ ene me.
• Ŋkɔ ŋɔŋlɔ ɖe nudede dɔa me kaba ƒe ɖoɖowo alo hehenana tɔxɛwo me le suku.

Amekawoe anɔ viwòa dzikpɔha me?

Beléle na viwòa ƒe ƒuƒoƒo sesẽ aɖe anɔ anyi be wòakpe ɖe viwòa ŋu wòakpɔ megalencephaly ƒe dzesiwo gbɔ. Ƒuƒoƒo sia ate ŋu anye:

• Ðeviwo ƒe dɔdalawo.
• Ahɔhɔ̃ŋutinunyalawo.
• Ahɔhɔ̃mekaŋutinunyalawo.
• Ŋgɔyiyi ŋuti nunyala bibiwo.
• Nuƒoƒo, dɔwɔɖui kple ŋutilãmedɔdalawo.

Aleke ɖevia ƒe etsɔme anɔ le nɔnɔme sia me?

Nu geɖe dzie viwòa ƒe nukpɔsusu nɔ te ɖo. Le kpɔɖeŋu me, alesi gbegbe dzesiawo nu sẽe kple nusi gbɔ wòtso. Ðewohĩ dzesi bubu aɖeke manɔ viwòa ŋu o negbe ta si lolo vie ko. Alo, dzesiawo ate ŋu akpɔ ŋusẽ ɖe viwòa ƒe tsitsi dzi. Le kpɔɖeŋu me, woate ŋu ahiã kpekpeɖeŋu bubu le gbesiagbedɔwo wɔwɔ me alo woate ŋu ahiã kpekpeɖeŋu le nusɔsrɔ̃ le suku me.

Nu vevitɔe nye be ɖevi ɖesiaɖe to vovo. Eya ta, ɖɔkta si da dɔ na viwòa koe ate ŋu ana nyatakaka siwo de pɛpɛpɛ wu tso viwòa ƒe nɔnɔme kple etsɔme ŋu.

Nukae nye agbenɔƒe si wokpɔ mɔ na kple `(Megalencephaly)`?

Ne nɔnɔmea mesẽ o, si fia be ne mesẽ o la, ɖewohĩ makpɔ ŋusẽ gã aɖeke ɖe ɖevia ƒe agbenɔƒe dzi o. Gake le nusi gbɔ wòtso nu la, le kpɔɖeŋu me, ne atikewɔwɔ me dɔléle sesẽ bubu kpe ɖe dɔlélea ŋu la, ɖevia ƒe agbenɔƒe ate ŋu anɔ kpuie vie. Dzesi sesẽwo abe asrãdɔ ene hã ate ŋu akpɔ ŋusẽ ɖe ɖevia ƒe etsɔme dzi. Wò ɖɔkta ate ŋu ana nyatakaka siwo ku ɖe viwòa ƒe nɔnɔme kple nu si nàkpɔ mɔ na ne ele tsitsim ŋu.

Ðe mɔ aɖe li si dzi woato axe mɔ ɖe nɔnɔme sia nua?

Fifia la, womenya mɔ aɖeke si dzi woato axe mɔ ɖe megalencephaly nu o. Gake ne ènya be dɔlélea le ame aɖe ŋu le wò ƒomea me alo ɖikeke si sɔ le ŋuwò la, àte ŋu aƒo nu kple domenyiŋusẽfianu ŋuti aɖaŋuɖola. Woate ŋu akpe ɖe ŋuwò nàda afɔku si le mewò be nàdzi vi si ŋu megalencephaly le la akpɔ.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Ne megalencephaly ƒe dzesi yeyewo alo esiwo le gbegblẽm ɖe edzi le viwò ŋu la, gblɔe na viwòa ƒe ɖɔkta. Ele vevie hã be nàŋlɔ viwò ƒe tsitsi ŋuti nuŋlɔɖi eye nàna wò ɖɔkta nanya ne viwòa mele tsitsime ƒe nu veviwo gbɔ ɖom o (e.g., anyinɔƒe kpekpeɖeŋu manɔmee, nya gbãtɔwo gbɔgblɔ) le eƒe ƒexɔxɔ nu.

Ne viwòa xɔ alɔ̃madɔmadɔ zi gbãtɔ la, ƒo ka na dɔwɔƒe siwo kpɔa nudzɔdzɔ kpatawo gbɔ enumake.

Vovototo kae le `(Macrocephaly)` kple `(Megalencephaly)` dome?

Wogayɔa `(Macrocephaly)` be `(Megacephaly)` alo `(Megalocephaly)`, elabena ta ƒe lolome lolo. Le `(Macrocephaly)` me la, ta ateŋu anye ɖevi ƒe ta gã, gake mehiã kokoko be kuxi aɖe nanɔ ahɔhɔ̃a ƒe wɔwɔme ŋu o.

`(Megalencephaly)` (ahɔhɔ̃ gã aɖe) ateŋu ahe `(Macrocephaly)` (ta gã aɖe) vɛ. Ke hã, `(Macrocephaly)` ateŋu atso `(hydrocephalus)` alo `(hydrocephalus)` hã ​​gbɔ. Kpuie ko la, `(Megalencephaly)` nye nusiwo gbɔ `(Macrocephaly)` tsona ɖeka ko.

Nukae nye esia `(Megalencephaly-capillary malformation - MCAP)`?

Megalencephaly-capillary malformation (MCAP) nye nɔnɔme si mebɔ o si me ŋutigbalẽ, ʋukawo, kadodoŋusẽ, kple ahɔhɔ̃mekawo tsina fũ akpa.

Zi geɖe la, ɖɔktawo kpɔa nɔnɔme si nye `(MCAP)` le vidzidzi me. Ðevi siwo wodzi kple `(MCAP)` la ƒe dzesi siawo dzena:

• Ahɔhɔ̃ si lolo (`Megalencephaly`).
• Ta gã aɖe (`Macrocephaly`).
• Capillary malformations - Esiawo nye ʋuka sue ŋutɔ siwo mesɔ o.

Nukae nye esia `(Megalencephaly-polymicrogyria-polydactyly-tsi ƒe tagbɔdɔ - MPPH)`?

Megalencephaly-polymicrogyria-polydactyly-hydrocephalus (MPPH) nye dɔléle si kpɔa ŋusẽ ɖe alesi viwòa ƒe ahɔhɔ̃ tsinae dzi. Ahɔhɔ̃ gã aɖe ate ŋu anɔ wo si (megalencephaly), eye ate ŋu adzi ɖe edzi kabakaba le woƒe agbenɔƒe eve gbãtɔwo me. Esia ate ŋu akpɔ ŋusẽ ɖe ɖevia ƒe tsitsi, eƒe ʋuʋu, kple eƒe nunya dzi.

Mlɔeba la, nu vevitɔ kekeake! (Gbedasi si Wotsɔ Yi Aƒeme)

Ne viwòa ƒe ta lolo wu eƒe ŋutilã ƒe akpa mamlɛa sã la, esɔ be nàtsi dzi. Ate ŋu axɔ ɣeyiɣi aɖe hafi viwòa nalé ta ɖe dzi le eɖokui si alo be ŋusẽ naɖo eŋu be wòanɔ anyi dzɔdzɔe. Viwòa dzikpɔha awɔ dodokpɔwo atsɔ anya nusita viwòa ƒe ahɔhɔ̃ lolo wu alesi wokpɔ mɔe.

Ðo ŋku edzi be ta gã mefia kuxi gã aɖe ɣesiaɣi o. Le go aɖewo me la, megalencephaly mesẽna o eye naneke metsi dzi ɖe eŋu o. Le go bubu me la, ɖevi aɖewo ate ŋu ahiã kpekpeɖeŋu kple kpekpeɖeŋu le woƒe agbemeŋkekewo katã me be woate ŋu akpɔ woƒe dzesiwo gbɔ. Nɔnɔme sia mekpɔa ŋusẽ ɖe ɖevi ɖesiaɖe dzi le mɔ ɖeka nu o. Srɔ̃ nu geɖe tso dɔléle si wokpɔ le viwòa ŋu kple nusi nàkpɔ mɔ na le etsɔme ŋu.Nyatakaka si de pɛpɛpɛ wu si nàte ŋu axɔ la tso ɖɔkta si le viwòa dam gbɔ. Mègavɔ̃ be yeabia nya wo ahaƒo nu tso nusianu si le susu me na wò ŋu o.

` Megalencephaly, Macrencephaly, ta gã, vidzĩ ƒe ta lolo, ahɔhɔ̃ ƒe lolome, ɖeviwo ƒe dɔlélewo, domenyiŋusẽfianu ƒe dɔlélewo, tsitsi ƒe megbetsitsi