Ðe ƒunukpeƒetetedɔ aɖe le wò kɔ mea? Mina míaƒo nu tso Papillary Thyroid Cancer (PTC) ŋu!

Ède dzesi ƒuƒu sue aɖe le wò kɔ me kpɔa? Alo ɖe ɖɔkta aɖe ƒo nu tso eŋu na wò le dodokpɔ aɖe wɔwɔ mea? Ɣeaɖewoɣi la, ƒu sue aɖe si le abe esia ene ate ŋu anye dɔléle aɖe si woyɔna be Papillary Thyroid Cancer (PTC) ƒe dzesi gbãtɔ. Mègatsi dzi o, míaƒo nu tso eŋu tsitotsito eye míaƒo nu tso eŋu bɔbɔe.

Nukae nye ʋumenugbagbeviɣidɔ si woyɔna be papillary thyroid carcinoma (PTC)? Nukae nye lãkusi si woyɔna be thyroid gland?

Kpuie ko la, papillary thyroid cancer (PTC) nye kansa ƒomevi aɖe si dona le míaƒe lãkusi me. Edzea egɔme tso lãmenugbagbevi siwo le lãkusi me me. Lãmenugbagbevi siawo wɔa protein aɖe si woyɔna be thyroglobulin . Nu vevitɔ si wòle be nànyae nye be PTC ye nye lãkusi me dɔdzẽ ƒomevi si bɔ wu .

Azɔ mina míalé ŋku ɖe nusi nye thyroid gland ŋu. Kpɔe ɖa le susu me, le wò kɔ ƒe ŋgɔgbe, le ŋutigbalẽ te, ŋutinu sue aɖe si le abe kpakpaluʋui ene. Emae nye lãkusi si woyɔna be thyroid gland. Esia nye míaƒe lãmenugbagbeviwo ƒe dɔwɔwɔ ƒe akpa aɖe . Eƒe dɔ vevitɔe nye be wòawɔ lãmetsi siwo kpɔa ŋusẽ ɖe míaƒe ŋutilã ƒe dɔ vevi geɖewo dzi ahaɖe wo ɖa.

Ne míeƒo nu tso PTC ŋu la, zi geɖe la, enyea kansa si tsina blewu ŋutɔ . Azɔ hã, zi geɖe la, lãkusia ƒe akpa ɖeka (lobe) koe wòdzɔna le.

Ðe `PTC` ƒe ƒomevi sue vovovowo lia?

Ẽ, `PTC` ƒe ƒomevi sue geɖewo li. Le esiawo dome la, follicular subtype ye bɔ ​​wu. Woyɔa esia ɣeaɖewoɣi be `mixed papillary-follicular variant`. Ƒomevi sue bubuawo mebɔ nenema gbegbe o. Gake woate ŋu atsi ahakaka kabakaba vie . Ƒomevi sue mawoe nye:

• `Kɔla`
• `Lãmenugbagbevi kɔkɔ`
• `ƒukpo dzi`
• `Sclerosis si kaka`

Ɣeaɖewoɣi la, wogayɔa `PTC` be `papillary thyroid carcinoma` .

Amekae xɔa papillary thyroid cancer?

Le nyateƒe me la, PTC ate ŋu adze ame sia ame dzi. Gake ebɔ wu le ame tsitsi siwo xɔ ƒe titina gome . Azɔ hã, nyɔnuwo ate ŋu axɔ nɔnɔme sia wu ŋutsuwo.

PTC nye nɔnɔme si mebɔ kura le ɖeviwo me o. Gake eyae nye lãkusi me dɔdzẽ ƒomevi si bɔ ɖe ɖeviwo me wu .

Aleke gbegbee `PTC` sia bɔe?

Thyroid cancer nye dɔléle si bɔ vie. Ke hã, abe alesi míegblɔe va yi ene la, dɔléleawo ƒe 80% va ɖo 85% nye PTC ƒomevi. Ema fia be ame siwo ade enyi le ewo ɖesiaɖe me siwo ŋu thyroid kansa le la ƒe dɔléle sia ƒomevi le wo ŋu.

Ðe `PTC` nye nɔnɔme sesẽ aɖea?

Kansa ƒomevi ɖesiaɖe nye nu sesẽ ŋutɔ. Ebia atikewɔwɔ eye ate ŋu akaka (akaka) ɖe ŋutilã ƒe akpa bubuwo. Gake PTC ƒe ŋgɔdonya nyo ŋutɔ ne wotsɔe sɔ kple lãkusi me dɔdzẽ ƒomevi bubuwo.

Zi geɖe la, woate ŋu ada PTC dzidzedzetɔe. Ƒã ŋutɔ hã be wòahe ku vɛ. Eyata ele vevie be míagatsi dzodzodzoe o eye nàwɔ ɖe atikewɔlawo ƒe aɖaŋuɖoɖo nyuiwo dzi.

Afikae `PTC` kaka ɖo gbã?

Ne PTC kaka la, anɔ eme wu be wòakaka ɖe ʋuka siwo le kɔa me la me gbã . Node siawo nye nu suesuesue siwo le abe gbe ene siwo nye míaƒe ŋutilã ƒe ʋukawo kple dɔlélenutsiŋutete ƒe akpa aɖe.

Afikae `PTC` kaka ɖo?

Togbɔ be PTC tsina blewu hã la, zi geɖe la, ate ŋu akaka ɖe ʋuka siwo le kɔ me. Ne míagblɔe teti la, amesiwo ŋu PTC le dometɔ siwo ade 30% akaka ɖe teƒe bubuwo (metastatic papillary thyroid cancer) le ɣeyiɣi si me wokpɔ dɔlélea .

Nukae nye `PTC` ƒe dzesiwo?

Zi geɖe la, PTC ƒe dzesi vevitɔe nye ʋuka si me vevesese mele o ƒe dzedzeme le lãkusi me . Dzesi bubuwo hã ate ŋu manɔ anyi o.

Gake ƒã ŋutɔ be ame aɖewo ate ŋu ase veve le kɔ, aɖu, alo to me . Ne ƒunukpeƒea lolo ale gbegbe be wòate ŋu aƒo míaƒe yaƒoƒomɔ̃ alo nuɖuɖutome la, ate ŋu ana gbɔgbɔ alo nu mimi nasesẽ na mí .

Vevietɔ: Ne ède dzesii be ƒu yeye aɖe le wò kɔ me, ne mevea wò o hã la, ele be nàyi ɖɔkta gbɔ godoo. Zi alesi nède dzesii kaba la, zi nenemae atikewɔwɔa kpɔa dzidzedzee.

Nukae nye nusiwo gbɔ `PTC` tsona?

Dzɔdzɔmeŋutinunyalawo menya nusi tututu gbɔ PTC tsona haɖe o , gake wode dzesi afɔku geɖe siwo nana dɔlélea xɔxɔ ƒe afɔkua dzina ɖe edzi, siwo dometɔ aɖewoe nye keklẽŋusẽ ƒe dɔwɔwɔ kple domenyiŋusẽfianu ƒe nɔnɔme aɖewo .

Kekeli ƒe keklẽ kple `PTC`

Ame siwo wodo go keklẽŋusẽ si nye ionizing radiation agbɔsɔsɔme ɖedzesi aɖe le woƒe ŋutinya me la ate ŋu axɔ PTC wu. Mɔ siwo dzi woate ŋu ato akpɔ keklẽŋusẽ siae nye:

• Wotsɔa gotagome keklẽŋusẽ ƒe atike gbogbo aɖewo naa kɔa tsɔ daa kansa alo nɔnɔme bubu siwo menye kansa o, vevietɔ le ɖevime.
• Kekeli si dona tso nukliaŋusẽdɔwɔƒe ƒe afɔkuwo me. Le kpɔɖeŋu me, le Chernobyl nukliafɔku si dzɔ le ƒe 1986 me megbe la, PTC dɔnɔ siwo le nuto siwo ƒo xlãe me ƒe xexlẽme dzi ɖe edzi tso zi gbɔ zi 3 va ɖo zi gbɔ zi 75.

Domenyiŋusẽfianu ƒe nɔnɔmewo kple `PTC`

Domenyiŋusẽfianu (domenyinyi) ƒe nɔnɔme geɖe li siwo do ƒome kple PTC:

• Ƒome ƒe Adenomatous Polyposis (FAP / Gardner syndrome): Esia nye dɔléle si mebɔ o, si ƒe dome wonyi. Enaa ame ƒe dɔgbo kple dɔgbo me ʋuka geɖe va nɔa eƒe dɔgbo kple dɔgbo me, si ate ŋu azu kansa. Amesiwo ŋu FAP le hã ate ŋu axɔ dɔdzẽ le ŋutilã ƒe akpa bubuwo, siwo dome lãkusi hã le. Dzɔdzɔmeŋusẽ ƒe tɔtrɔ si ƒe dome wonyi le APC domenyiŋusẽfianu me gbɔe nɔnɔmea tsona.
• Werner ƒe dɔléle : Esia hã nye dɔléle si mebɔ o. Eɖea tsitsi kabakaba si mesɔ o (progeria) ƒe dzesiwo fiana. Amesiwo ŋu Werner ƒe dɔlélea le la le afɔku me be woaxɔ kansa. Wo dometɔ si bɔ wue nye lãkusi me dɔdzẽ. Wokpɔ tɔtrɔ vovovo siwo wu 80 le WRN domenyiŋusẽfianu me le amesiwo ŋu dɔléle sia le ŋu.
• Carney complex type 1 : Nɔnɔme sia hã nana be dɔdzẽ ƒomevi vovovowo, siwo dome lãkusi me dɔdzẽ hã le, xɔxɔ ƒe afɔkua dzina ɖe edzi. Zi geɖe la, PRKAR1A domenyiŋusẽfianu ƒe tɔtrɔ gbɔe wòtsona.

Ke hã, ele be woaɖo ŋku edzi be PTC dɔnɔwo katã ƒe 5% koe do ƒome kple domenyiŋusẽfianu ƒe nɔnɔme mawo.

Aleke woawɔ ade dzesi `PTC`?

Zi geɖe la, PTC dzena abe ƒunukpeƒetetedɔ ene le lãkusi me. Ðewohĩ wò ŋutɔ èse le ɖokuiwò me kpɔ, alo ɖɔkta aɖe ate ŋu akpɔe le kɔ dodokpɔ si wowɔna edziedzi me. Ɣeaɖewoɣi la, wokpɔa ƒunukpeƒea le vo me ne wole ŋku lém ɖe nɔnɔme bubu aɖe ŋu.

Wò ɖɔkta ate ŋu aɖe gbe be woawɔ dodokpɔ siwo gbɔna atsɔ anya PTC:

• Nɔnɔmetatawo dodokpɔ : Dodokpɔ siawo ate ŋu akpe ɖe ame ŋu woade dzesi thyroid nodule. Le kpɔɖeŋu me, woate ŋu awɔ thyroid ultrasound , CT scan , kple/alo MRI scan .
• Fine needle aspiration (needle biopsy ): Zi geɖe la, ɖɔkta atsɔ aŋe si le sue ŋutɔ aɖe lãmenugbagbevi sue aɖe (biopsy) tso wò thyroid nodule me. Dɔléleŋutinunyala aɖe alé ŋku ɖe lãkusia ŋu le nusuekpɔmɔ̃ me akpɔe ɖa be kansadɔlékui aɖewo li hã, eye ne ele nenema la, alé ŋku ɖe lãkusi me dɔdzẽ ƒomevi si wònye hã ŋu.

Ɣeaɖewoɣi la, wò ɖɔkta ate ŋu aɖo wò ɖe domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo na wò be wòakpɔe ɖa be domenyiŋusẽfianu ƒe dɔléle aɖe le ŋuwò si hea PTC vɛ, kpakple dɔdzẽ ƒomevi bubuwo hã.

Aleke wowɔa atike na PTC?

PTC dada nɔ te ɖe dɔdzẽa ƒe lolome kple ne kansa la kaka dzi.

Amekokoe nye atike vevitɔ kple esi bɔ wu na PTC.Le dɔdzẽa ƒe lolome kple afisi wòle nu la, wò amekola ate ŋu aɖe lãkusi ƒe akpa aɖe (lobectomy) alo lãkusi bliboa (thyroidectomy). Ne dɔdzẽa le lãkusiwo me la, amekolaa ate ŋu aɖe lãkusi siwo ŋu dɔlélea le la ɖa le ɣeyiɣi ma ke si me wowɔ dɔ na lãkusia alo le amekoko evelia me.

Vevietɔ: Ne woɖe wò lãkusi bliboa ɖa (woɖe wò lãkusi bliboa ɖa) la, ahiã be nàno lãkusi me lãmetsiŋusẽtikewo le wò agbemeŋkekewo katã me .

Atike bubu siwo woate ŋu azã na PTCe nye:

• Radioiodine zazã : Thyroid lãmenugbagbeviwo kple PTC lãmenugbagbeviwo xɔa mineral iodine (si le nuɖuɖu aɖewo me). Le susu sia ta la, ɣeaɖewoɣi ɖɔktawo zãa iodine si me keklẽŋusẽ le tsɔ tsrɔ̃a lãkusi ɖesiaɖe si sɔ si susɔ ne woɖe lãkusia ɖa vɔ, kpakple lãkusi ɖesiaɖe si me kansa le si ate ŋu asusɔ.
• Kekeli ƒe atikewɔwɔ : Kekeli wua kansa lãmenugbagbeviwo eye wòxea mɔ na wo be woagatsi o. Le gotagome keklẽŋusẽdɔdamɔnu me la, mɔ̃ aɖe fiaa mɔ ŋusẽ ƒe keklẽ sesẽwo yia dɔdzẽa gbɔ tẽ. Le ememe keklẽŋusẽdɔdamɔnu me la, wotsɔa nuku siwo me keklẽŋusẽ le dea dɔdzẽa me alo ƒo xlãe.
• Atikewɔwɔ : Atike siwo wodona ɖe ʋuka me (IV) alo to nu me (nu me) wua kansa lãmenugbagbeviwo eye woxea mɔ na kansa la ƒe tsitsi. Gake amesiwo ŋu thyroid kansa le ƒe alafa memamã sue aɖe koe hiã atikewɔmɔnu.

Nukae nye `PTC` dɔdamɔnu ƒe nugbegblẽ le ame ŋu kple kuxi siwo dona tso eme?

Nusi ate ŋu agblẽ le ʋumenugbagbeviɣidɔ kple radioiodine zazã ŋue nye ʋumenugbagbeviɣidɔ si nɔa anyi ɖaa. Eyata ne atike siawo dometɔ ɖeka alo evea siaa le asiwò la, ahiã be nàno thyroid hormone ƒe atikekuiwo le wò agbemeŋkekewo katã me.

Kuxi geɖe li siwo ate ŋu ado mo ɖa le lãkusi ƒe dɔwɔwɔ na ame me:

• Dɔdzedze.
• Parathyroid glands , siwo kpɔa calcium ƒe agbɔsɔsɔ si le wò ʋu me dzi ɖeɖeɖa le vo me alo woƒe gbegblẽ.
• Nusiwo gblẽ le lãkusi ƒe lãmeka si gbugbɔna, si zɔna le lãkusia megbe ŋu. Esia ate ŋu ana gbea natsi eye wòagbɔdzɔ.

Nusiwo ate ŋu ado tso iodine si me keklẽŋusẽ le zazã me:

• Aɖuɖɔtoe kple ʋuʋudedi.
• Sialadenitis - aɖuɖɔtoe si vuvu.
• Thyrotoxicosis si nɔa anyi ɣeyiɣi kpui aɖe.
• Aklã me fibrosis nye dɔléle si nana abi nɔa aklã ƒe lãkusi ŋu.
• Vidzidzimakpɔmakpɔ ɣeyiɣi kpui aɖe alo tegbee.
• ƲumenugbagbeviɣidɔAfɔku sue aɖe si le ʋumenugbagbeviɣidɔ, no me dɔdzẽ, alo tsinyegoe me dɔdzẽ xɔxɔ me.

Ðe woate ŋu axe mɔ ɖe `PTC` nua?

Ame geɖe siwo xɔa thyroid kansa la mekpɔa afɔku aɖeke koŋ o. Eyata womate ŋu axe mɔ ɖe PTC ƒe dɔléle akpa gãtɔ nu o.

Kekeli ƒe keklẽ, vevietɔ le ɖevime, nye afɔku si wonya be wòaxɔ PTC. Le esia ta la, ɖɔktawo megazãa keklẽŋusẽ na dɔléle siwo mesẽ boo o. Ðeviwo hã doa go keklẽŋusẽ si dona tso nɔnɔmetata dodokpɔwo abe X-ray kple CT scan ene me, gake le agbɔsɔsɔ si bɔbɔ wu kura me. Womenya afisi wodzia PTC ƒe afɔkua ɖe edzi ase ɖo o.

Ne ʋumenugbagbeviɣidɔ dze ame aɖe dzi le wò ƒomea me la, àte ŋu axɔ domenyiŋusẽfianu ŋuti aɖaŋuɖoɖo . Esia akpe ɖe ŋuwò nànya ne domenyiŋusẽfianu ƒe dɔléle aɖe le ŋuwò si ana nànɔ afɔku gã aɖe me be nàxɔ PTC. Ne èwɔe alea la, wò ɖɔkta ate ŋu aɖo aɖaŋu be nàwɔ dɔ na wò atsɔ axe mɔ ɖe dɔlélea nu be woaɖe wò lãkusi hafi kansa nadze egɔme.

Nukae nye PTC ƒe ŋgɔdonya?

Le goawo katã me la, PTC ƒe nyagblɔɖi nyo ŋutɔ , vevietɔ ne mèxɔ ƒe 40 haɖe o eye dɔdzẽa le sue. Zi geɖe la, woate ŋu ada PTC dzidzedzetɔe. Ne ekaka ɖe ʋuka siwo le kɔ me gɔ̃ hã la, ƒã hafi wòwua ame.

Nusiwo ate ŋu aɖe ame ƒe hayahaya ƒe agbɔsɔsɔ dzi akpɔtɔ dometɔ aɖewoe nye:

• Ƒe 55 kple edzivɔ xɔxɔ le dɔlélea didi me.
• Dɔdzẽa le lolom ɖe edzi .
• Kansa la kaka ɖe ŋutilã ƒe akpa siwo le didiƒe ʋĩ .
• `PTC` ƒe ƒomevi sue si mebɔ o, si wɔa adã ƒe amesinɔnɔ (e.g. `lãmenugbagbevi kɔkɔ ƒe tɔtrɔ`, `diffuse sclerosis ƒe tɔtrɔ`, `sesẽ ƒe tɔtrɔ`).

Àte ŋu atsi agbe le `PTC` mea?

Agbetsitsi ƒe agbɔsɔsɔme le PTC me sɔ gbɔ ŋutɔ . Ame tsitsi siwo ŋu PTC le ƒe 90% kple edzivɔ nɔa agbe ƒe 10 va ɖo 20 ya teti le atikewɔwɔ vɔ megbe.

Ɣekaɣie wòle be makpɔ ɖɔkta tso `PTC` ŋu?

Ne wokpɔe be PTC le ŋuwò la, ahiã be nàdo go kple wò atikewɔlawo ƒe ƒuƒoƒoa edziedzi be woalé ŋku ɖe wò atikewɔwɔ ƒe ŋgɔyiyi ŋu. Ahiã hã be nàva srã wò kpɔ ɣeyiɣi didi ɣleti 6 va ɖo 12 ɖesiaɖe hena ƒe atɔ̃ ya teti be nàlé ŋku ɖe eŋu be egadzɔ ake hã.

Ne woɖe wò thyroid gland ɖa eye/alo wona radioactive iodine dɔdamɔnu na wò abe wò atikewɔwɔ ƒe akpa aɖe ene la, ahiã be nàno thyroid hormone ƒe atikekuiwo le wò agbemeŋkekewo katã me . Ðɔkta alé ŋku ɖe wò lãkusi me lãmetsiŋusẽ ƒe agbɔsɔsɔ ŋu le wò agbemeŋkekewo katã me be wòakpɔ egbɔ be wò atike ƒe agbɔsɔsɔme sɔ na wò.

Ne wokpɔ kansa le ŋuwò, eɖanye ƒomevi ka kee wòɖanye o, ate ŋu awɔ nuku na ame. Gake nya nyuiae nye be zi geɖe la, PTC ƒe nyagblɔɖi nyo ŋutɔ. Wò atikewɔlawo ƒe ƒuƒoƒoa awɔ dɔ kpli wò akpɔ atikewɔwɔ ƒe ɖoɖo nyuitɔ kekeake na wò.

## Nu vevi siwo dzi wòle be woaɖo ŋkui (Take-Home Message)

Enyo, eyata, le nusiwo ŋu míeƒo nu tsoe nu la, esiawoe nye nu vevitɔ kekeake siwo dzi wòle be nàɖo ŋkui:

• Papillary thyroid cancer (PTC) ye nye thyroid cancer ƒomevi si bɔ wu eye eƒe ŋgɔdonya nyuitɔ kekeake.
• Dzesi vevitɔe nye ƒuƒu si me vevesese aɖeke mele o le kɔ me. Ne èkpɔ nane si le abe ema ene la, yi ɖɔkta gbɔ godoo.
• Amekokoe nye atikewɔwɔ vevitɔ. Ðewohĩ ahiã be woatsɔ iodine si me keklẽŋusẽ le zazã hã ahiã.
• Ne woɖe lãkusia ɖa keŋkeŋ la, ahiã be nàno lãkusi me lãmetsiwo le wò agbemeŋkekewo katã me .
• Zi alesi wokpɔ nɔnɔme sia kaba la, zi nenemae atikewɔwɔa kpɔa dzidzedzee. Eyata atikewɔlawo ƒe dodokpɔ edziedzi kple aɖaŋuɖoɖowo dzi wɔwɔ le vevie ŋutɔ.
• Mègavɔ̃ o. Menye wò ɖeka koe o. Ðɔktawo, ƒometɔwo, kple xɔlɔ̃wo li siwo akpe ɖe ŋuwò.

Mele mɔ kpɔm be nyatakaka sia akpe ɖe ŋuwò. Ne nya aɖe le asiwò la, mègahe ɖe megbe le wò ɖɔkta biabia me o. Nɔ lãmesẽ me!

` Thyroid cancer, papillary thyroid cancer, PTC, kɔ me nodules, thyroid ƒe amekoko, keklẽŋusẽdɔdamɔnu, lãmetsiŋusẽtike