Ðe wò lãmekawo le gbɔdzɔgbɔdzɔm vivivia? Ðewohĩ mànya be Primary Lateral Sclerosis (PLS) ye o! Mina míaƒo nu tso esia ŋu!

Ðe wòsena le ɖokuiwò me ɣeaɖewoɣi be yeƒe afɔwo kple abɔwo le ƒoƒom vivivi, alo wò ŋusẽ dzi le ɖeɖem kpɔtɔa? Ðe nèsena le ɖokuiwò me be ŋusẽ megale ye ŋu abe tsã ene o ne èle zɔzɔm, eye ɖewohĩ mègada asɔ gɔ̃ hã oa? Togbɔ be esiawo nye dzesi siwo ŋu ɖewohĩ màlé ŋku ɖo boo o hã la, ɣeaɖewoɣi la, susu sesẽ aɖe ate ŋu anɔ megbe na wo. Emae nye nusi Primary Lateral Sclerosis nye, alo PLS kpuie.

Mina míakpɔ nusi PLS sia fia ko ɖaa?

Kpuie ko la, PLS nye ahɔhɔ̃mekawo ƒe dɔléle si yia edzi ɖaa. Enaa wò lãmekawo gbɔdzɔna vivivi eye/alo wosẽna. Zi geɖe la, dzesiawo dzea egɔme tso wò afɔwo dzi. Le ɣeyiɣi aɖe megbe la, gbɔdzɔgbɔdzɔ kple sesẽ sia ate ŋu akaka ɖe wò ŋutilã ƒe lãmeka bubuwo me.

Bu eŋu ale: míaƒe lãmekawo wɔa dɔ abe elektrikmɔ̃ ene. Ele be woaxɔ ‘fifia’, gbedasi si tso ahɔhɔ̃a gbɔ, abe alesi wòle be wòaxɔe ene pɛpɛpɛ. Le PLS me la, lãmeka siwo woyɔna be Upper Motor Neurons (UMN), siwo le abe ‘ka’ siwo tsɔa gbedasi siawo ene la gblẽna.

Nublanuitɔe la, atike aɖeke meli na PLS fifia o. Eyata atikewɔwɔ koŋue nɔa te ɖe wò dzesiwo dzi ɖuɖu kple kpekpeɖeŋu nana wò be nàwɔ gbesiagbedɔwo bɔbɔe wu dzi. Le kpɔɖeŋu me, kpekpeɖeŋu nana wò be nàzã atizɔti alo afɔti.

Aleke gbegbee PLS bɔe?

Le nyateƒe me la, PLS nye nɔnɔme si mebɔ kura o. Akɔntabubu aɖeke meli ku ɖe ame agbɔsɔsɔme si tututu wòxɔna ŋu haɖe o.

Vovototo kae le PLS kple ALS dome? Ðe PLS ate ŋu anye ALS?

Ðewohĩ èse ALS, alo Amyotrophic Lateral Sclerosis ŋu nya kpɔ. PLS kple ALS siaa nye lãmekawo kple lãmekawo ƒe dɔlélewo. Gake vovototo vevi aɖewo le wo ame evea dome.

Vovototo vevitɔe nye be wò lãmeka siwo le etame (UMNs) koe PLS gblẽa nu le . Esiawoe nye lãmeka siwo tsɔa gbedasiwo tso ahɔhɔ̃a me yia aklã me. Le ALS me la, ekpɔa ŋusẽ ɖe UMN siawo hã dzi, eye nenema kee wògblẽa nu le ahɔhɔ̃meka siwo le ete (LMNs) , siwo tsɔa gbedasiwo tso aklã me yia lãmekawo me hã dzi.

Fifia ɖewohĩ ànɔ ɖokuiwò biam be, ‘Ekema ɖe ame aɖe si ŋu PLS le ate ŋu axɔ ALS emegbea?’ Ẽ, mɔnukpɔkpɔ li be ate ŋui. Ɣeaɖewoɣi la, ALS ƒe dzesi gbãtɔwo ate ŋu asɔ kple PLS tɔ. Ne dzesi siwo gblẽa nu le UMN ɖeɖeko ŋu le ŋuwò la, woate ŋu akpɔe be PLS le ŋuwò le gɔmedzedzea me. Gake ne ALS ƒe dzesi siwo gblẽa nu le UMN kple LMN siaa ŋu va dze dziwò emegbe la, wò ɖɔkta ate ŋu atrɔ wò dɔlélea wòazu ALS.

Le nyateƒe me la, dɔléle geɖe siwo le abe PLS ene ate ŋu anye ALS ƒe dzesi gbãtɔ siwo gblẽa nu le UMN (`UMN-predominant ALS`) ŋu. Esia tae ɖɔktawo gblɔna be hafi woakpɔe be PLS le ŋuwò godoo la, ele be dzesiwo nanɔ ŋuwò ƒe etɔ̃ va ɖo ene ya teti .

Nukawoe nye PLS ƒe dzesiwo?

PLS ƒe dzesiwo dzena blewu ŋutɔ.Màse vovototo gã aɖeke le ɖokuiwò me enumake o.

Dzesi siwo woate ŋu akpɔ le eƒe gɔmedzedze:

Gbã la, àte ŋu ase nanewo abe esia ene:

• Afɔwo ƒe sesẽ. Ate ŋu ase le eɖokui me abe ɖe wò afɔwo tsi ene.
• Lãmetsi siwo le wò afɔwo me la gbɔdzɔna. Ðewohĩ àse le ɖokuiwò me be ŋusẽ megale ye ŋu abe tsã ene o.
• Eva sesẽna na wò be nàzɔ, alo be nàda asɔ. Àte ŋu akli nu alo adze anyi.
• Lãmetsiwo ƒe ʋuʋu alo lãmekawo ƒe ʋuʋu si me vevesese le dzɔna.

Dzesi siwo ate ŋu adze ne dɔlélea le sesẽm ɖe edzi:

Ne dɔlélea le sesẽm ɖe edzi la, dzesi bubuwo abe esiawo ene ate ŋu adze:

• Lãmetsi siwo le asibidɛwo, asiwo, kple abɔwo hã me sẽna eye wogbɔdzɔna. Ate ŋu asesẽ be woase nu suewo alo nuŋɔŋlɔ.
• Aɖuɖɔtoe dzi ɖuɖu sesẽ. Esia ate ŋu ana ame naɖe aɖuɖɔ kpata eye wòagate ŋu aɖu aɖuɖɔ o.
• Vevesese dzɔna le akɔta kple kɔ ƒe akpa si le anyime.

Dzesi siwo mebɔ o siwo gblẽa nu le aɖe ƒe lãmekawo ŋu:

Esia mebɔ kura o, gake ame aɖewo hã ate ŋu agblẽ nu le aɖe ƒe lãmekawo ŋu. Ne esia dzɔ la:

• Nuƒoƒo si me mekɔ o (dysarthria) dzɔna. Eva sesẽna be woayɔ nyawo nyuie.
• Nu mimi sesẽ (dysphagia). Ðewohĩ àse le ɖokuiwò me be yeƒe lãme le ƒoƒom ne yemi nuɖuɖu alo nunono.

Nukae hea PLS vɛ?

Zi geɖe la, míenya nusi tututu gbɔ PLS tsona haɖe o. Nyateƒeae nye ema.

Ke hã, ƒã ŋutɔ be PLS ƒomevi aɖe li si dzea ɖevi suewo kple sɔhɛ tsitsiwo dzi (`juvenile primary lateral sclerosis`). Esia tsoa tɔtrɔ si vaa woƒe DNA me le fufɔɣi gbɔ.

Nukae dzɔna ɖe míaƒe ŋutilã dzi tso PLS gbɔ?

PLS nye ahɔhɔ̃mekawo ƒe dɔléle. Ekpɔa ŋusẽ ɖe ahɔhɔ̃meka siwo wɔa dɔ le wò ahɔhɔ̃ me kple lãmeka siwo tso ahɔhɔ̃meka mawo gbɔ va ɖoa aklã me koŋ dzi. Wogayɔa esiawo be upper motor neurons ( UMN).

Bu eŋu kpɔ, ne èdi be yeaʋuʋu yeƒe afɔ la, wò ahɔhɔ̃ ɖoa gbedasi aɖe ɖa. Gbedasi sia zɔa mɔ to lãmekawo me yia ahɔhɔ̃meka siwo le aklã me, eye tso afima yia wò afɔ ƒe lãmeka siwo nèlɔ̃na faa la gbɔ. Ne lãmekawo xɔ gbedasi sia la, woʋãna.

Le PLS me la, UMN ƒe lãmeka siawo kuna vivivi (woƒe gbegblẽ). Emegbe, lãmekaawo mexɔa gbedasi siwo hiã la nyuie o, eyata lãmekaawo mewɔa dɔ abe alesi wokpɔ mɔe ene o.

Ðe esia nye domenyiŋusẽfianu ƒe dɔlélea?

Zi geɖe la, menye domenyiŋusẽfianue PLS tsona o. Esia fia be àte ŋu atue ɖo ne ame aɖeke mexɔe le wò ƒomea me kpɔ o gɔ̃ hã. Zi geɖe la, edzɔna le vome, eye dɔlélea aɖeke mele ƒomea me o.

Amekawoe le afɔku gã me be woaxɔ PLS?

PLS ate ŋu akpɔ ŋusẽ ɖe amesiame dzi ŋutɔŋutɔ. Zi geɖe la, wokpɔnɛ le ƒe 50 lɔƒo. Gake ate ŋu adze amesiwo mexɔ ƒe 50 haɖe o, ame tsitsiwo, kple ɖeviwo gɔ̃ hã dzi. Ebɔ ɖe ŋutsuwo me vie wu.

Kuxi kawoe ate ŋu ado mo ɖa le PLS ta?

Ne PLS le ŋgɔ yim la, ate ŋu asesẽ na wò be nàzɔ kpekpeɖeŋu manɔmee. Ðewohĩ ahiã be nàzã atikplɔ, afɔzɔla, alo bunɔkeke. Tsɔ kpe ɖe eŋu la, ne wò lãmekawo le gbɔdzɔgbɔdzɔm la, màgate ŋu ada asɔ o eye nàdze anyi bɔbɔe. Ne èwɔe alea la, àte ŋu axɔ abi.

Aleke wowɔa dea dzesi PLS?

Ðɔkta akpɔ PLS le ŋutilãmedodokpɔ, ahɔhɔ̃mekadodokpɔ, kple dodokpɔ tɔxɛ bubu aɖewo megbe. Woato wò dzesiwo me eye woadze agbagba be yewoaɖe nɔnɔme bubu siwo ƒe dzesiwo sɔ kple wo nɔewo, abe ALS alo lãmekawo ƒe dɔléle ene, ɖa. Woate ŋu azã dodokpɔ siwo gbɔna atsɔ anya dɔlélea:

• Ʋudodokpɔwo.
• Electrodiagnostic examinations - Esiawo léa ŋku ɖe alesi wò lãmekawo kple lãmekawo le dɔ wɔm nyuie ŋu. Kpɔɖeŋu aɖewoe nye lãmekawo ƒe ʋuʋu ŋuti numekukuwo kple aŋe ƒe elektrikŋusẽ ŋuti numekukuwo.
• MRI (Magnetic Resonance Imaging) dodokpɔ si wowɔna le ahɔhɔ̃ kple aklã ŋu.
• Ahɔhɔ̃ me tsi (CSF) me dzodzro. Wowɔa esia to tsi sue aɖe ɖeɖe le wò akɔta (akɔta ƒe ʋuʋu alo aklã ƒe pɔmpi) me be woadi nusiwo mesɔ o siwo ku ɖe ahɔhɔ̃mekawo ƒe dɔlélewo koŋ ŋu.

Nukawoe nye atike siwo wozãna na PLS?

PLS dada ƒe taɖodzinue nye be wòakpe ɖe ŋuwò nàkpɔ wò dzesiwo gbɔ. Esia ate ŋu alɔ:

• Atike siwo woatsɔ aɖe lãmekawo ƒe sesẽ, lãmekawo ƒe ʋuʋu, kple nu mimi sesẽ dzi akpɔtɔ.
• Lãmesẽfefewɔwɔ be woatsɔ aɖe lãmekawo ƒe gbɔdzɔgbɔdzɔ dzi akpɔtɔ, ana lãmekawo nate ŋu atrɔ ɖe nɔnɔmewo ŋu nyuie wu, eye woana ƒunukpeƒewo nate ŋu aʋã nyuie wu.
• Mɔ̃ siwo kpena ɖe ame ŋu le gbesiagbedɔwo kple ʋuʋu me. Le kpɔɖeŋu me, atikplɔ, afɔzɔla, alo bunɔkeke.
• Nuƒoƒo ƒe atikewɔwɔ alo mɔ̃ siwo akpe ɖe ame ŋu le nuƒoƒo ƒe kuxiwo me.

Atike siwo wonana na PLS ƒe dzesiwo:

Atike siwo woŋlɔna na PLS ƒe dzesiwo zi geɖe dometɔ aɖewoe nye:

• Le lãmekawo ƒe sesẽ gome la: `(Baclofen)` kple `(Tizanidine)`
• Lãmetsiwo ƒe ʋuʋu: `(Quinine)`
• Be nàɖe dzi ɖi na lãmekawo: `(Diazepam)`

Ðe atikewɔwɔa ƒe nugbegblẽ aɖewo lia?

Ẽ, abe atikewo katã ene la, esia ate ŋu agblẽ nu le ame ŋu. Nusiwo wògblẽna le ame ŋu la toa vovo le atike si wozãna nu. Eyata ele vevie ŋutɔ be nàƒo nu tso nusiwo ate ŋu ado tso eme ŋu na wò ɖɔkta hafi adze atike ɖesiaɖe zazã gɔme.

Ðe woate ŋu axe mɔ ɖe PLS nu alo adaea?

Esi womenya nusi tututu gbɔ PLS tso o ta la, mɔ aɖeke meli si dzi woato axe mɔ ɖe enu fifia o.

Azɔ hã, nublanuitɔe la, fifia la, atike aɖeke meli si ate ŋu ada PLS keŋkeŋ o.

Nukae nye ame si ŋu PLS le ƒe agbenɔƒe? Nukae woate ŋu akpɔ mɔ na?

PLS mekpɔa ŋusẽ ɖe wò agbenɔƒe dzi tẽ o. Ame si ŋu PLS le ate ŋu anɔ agbe abe alesi wòle le amesi ŋu dɔlélea mele o ene.

Alesi wò dzesiwo dzena kabakaba kple alesi wogblẽna kabakabae la toa vovo tso ame ɖeka gbɔ yi bubu gbɔ. Le goawo katã me la, axadzi ƒe ʋuʋu gbãtɔ yia edzi blewu ŋutɔ, le ƒe geɖe me, ɣeaɖewoɣi ƒe bla nanewo. Gake ne kasia nèse le ɖokuiwò me be yeƒe dzesiwo le sesẽm ɖe edzi la, yi ɖɔkta gbɔ enumake.

Atikewo ate ŋu akpe ɖe ŋuwò nàɖe wò dzesiwo dzi akpɔtɔ eye wòakpe ɖe ŋuwò nàwɔ wò gbesiagbedɔwo madzudzɔmadzudzɔe. Àte ŋu abu atizɔti, afɔzɔla, alo bunɔkeke zazã ŋu be wòakpe ɖe ŋuwò nàse le ɖokuiwò me be yele dedie wu eye kakaɖedzi le ye ŋu ne èle tsa ɖim.

Ɣekaɣie wòle be nàkpɔ ɖɔkta?

Ne ède dzesi tɔtrɔ aɖewo vivivi le wò lãmekawo me, abe lãmekawo ƒe sesẽ alo gbɔdzɔgbɔdzɔ ene la, ƒo nu kple wò ɖɔkta. Ne wokpɔe be PLS le ŋuwò, ne atike aɖe si zãm nèle le wò dzesiawo gblẽm ɖe edzi, alo ne èle eƒe nugbegblẽ le ame ŋu kpɔm la, gblɔ ema hã na wò ɖɔkta.

Vevietɔ wu: Ne èdze anyi alo nèxɔ abi le afɔku aɖe me la, yi xɔ si me wowɔa dɔ kpata le enumake.

Nya siwo wòle be nàbia wò ɖɔkta

Ne PLS le ŋuwò la, nya geɖe anɔ asiwò nàbia wò ɖɔkta. Le kpɔɖeŋu me:

• Atikewɔwɔ kawoe ate ŋu akpe ɖe ŋunye maɖu nye dɔlélea ƒe dzesiwo dzi?
• Nukawoe nye atikewɔwɔa ƒe nugbegblẽ le ame ŋu?
• Aleke mawɔ anya ne nye nɔnɔmea agblẽ ɖe edzi le ɣeyiɣi aɖe megbe?
• Kamedede kawoe mate ŋu awɔ be nye lãmekawo nayi edzi awɔ dɔ?
• Ðe wòhiã be mazã atikplɔ alo afɔdzidela?

Mlɔeba la, Gbedasi si Wotsɔ Yi Aƒeme

Tɔtrɔ ɖe nɔnɔme si le ŋgɔ yim si gblẽa nu le wò ŋutete be nàʋuʋu wò ŋutilã ŋu ate ŋu asesẽ ŋutɔŋutɔ. Nu siwo wɔwɔ doa dzidzɔ na wò tsã la dometɔ aɖewo ate ŋu ava sesẽ vivivi. Togbɔ be primary lateral sclerosis (PLS) yia ŋgɔ vivivi hã la, ate ŋu akpɔ ŋusẽ ɖe wò gbesiagbegbenɔnɔ dzi.

Ne ŋutilã me tɔtrɔ siawo hã le ŋusẽ kpɔm ɖe wò seselelãme dzi la, àte ŋu akpɔ gbɔdzɔe ne èƒo nu kple susumedɔdala aɖe .Menye naneke si ŋu wòakpe ŋu le o, ame geɖe hiãa kpekpeɖeŋu le ɣeyiɣi siawo tɔgbe me.

Ne ède dzesii be yeƒe lãmekawo ƒe ŋusẽ trɔ la, yi ɖɔkta gbɔ enumake. Woate ŋu aŋlɔ atikewo alo mɔ̃ siwo wotsɔ ʋãa ame be wòakpe ɖe ŋuwò nànɔ ɖokuiwò si eye nàvo. Ðo ŋku edzi be menye wò ɖeka koe le mɔzɔzɔ sia me o.

` Primary lateral sclerosis, PLS, lãmekawo ƒe gbɔdzɔgbɔdzɔ, ahɔhɔ̃mekawo ƒe dɔléle, motor neurons, ALS, dzesiwo