Ðe ɖeɖi tea ŋuwò le mɔ si mebɔ o nu alo ɖeɖi tea ŋuwò ɣeaɖewoɣi le susu aɖeke manɔmeea? Ðe wò ŋutigbalẽ dzena ɣiea? Alo ɖe viwò si wodzi yeyee ƒe ʋuʋudedi medzona le kwasiɖa eve megbe oa? Nusi gbɔ nusiawo tso ate ŋu anye enzyme aɖe si woyɔna be G6PD ƒe anyimanɔmanɔ le wò ŋutilã me. Mègatsi dzi o, nɔnɔme sia nye esi bɔ ŋutɔ. Egbea, míaƒo nu bɔbɔe eye eme nakɔ tso nusi G6PD nye, nusi dzɔna ne ebɔbɔ, kple G6PD dodokpɔa ŋu.
Nukae nye G6PD ko?
Bu ʋumenugbagbevi dzĩ siwo le míaƒe ŋutilã me abe asrafo siwo le dɔ wɔm ene ŋu kpɔ. ‘Dzɔla’ aɖe li si kpɔa asrafo siawo ta tso nu gbegblẽ vovovowo me. Dzɔla ma nye enzyme aɖe si woyɔna be G6PD.
Kpuie ko la, G6PD (Glucose-6-Phosphate Dehydrogenase) nye enzyme vevi aɖe ŋutɔ si kpɔa míaƒe lãmenugbagbeviwo, vevietɔ ʋumenugbagbevi dzĩ siwo le míaƒe ʋu me, ta tso atike siwo gblẽa nu le ame ŋu me. Míaƒe ŋutilã wɔa nusiwo gblẽa nu le ame ŋu (siwo woyɔna hã be ‘Free Radicals’ alo ‘Reactive Oxygen Species’ ) siwo dona le dɔwɔwɔ nyuie me. G6PD enzyme wɔa esia to mɔxexe ɖe nu gbegblẽ siawo nu be woagaƒo ƒu ahagblẽ nu le lãmenugbagbeviwo ŋu o.
Nukae dzɔna ne G6PD le sue?
Azɔ bu nusi adzɔ ne ‘ametakpɔnu’ (G6PD) ma le sue le ŋutilãa me ŋu kpɔ? Emegbe nu gbegblẽ mawo va dzea míaƒe ʋumenugbagbevi dzĩwo tsɔtsrɔ̃ gɔme. Woyɔa ʋumenugbagbevi dzĩwo ƒe gbagbã kabakaba wu alesi woate ŋu awɔe ƒe ɖoɖo sia be ʋumenugbagbeviɣidɔ .
Ne ʋumenugbagbevi dzĩ gbogbo aɖewo bu na wò le mɔ sia nu la, wò ŋutilã mekpɔa ɔksidzin si wòhiã o. Emae míeyɔna be ʋusɔgbɔdɔ, alo ne míagblɔe tututu la, ʋusɔgbɔdɔ si me ʋu sina tona . Esia tae nèsena le ɖokuiwò me be ɖeɖi te ye ŋu, yegbɔdzɔ, eye yeƒe mo biã ɣesiaɣi ɖo.
Aleke G6PD ƒe anyimanɔmanɔ dzɔnae?
G6PD ƒe anyimanɔmanɔ nye domenyiŋusẽfianu ƒe nɔnɔme si tso domenyiŋusẽfianu me . Esia fia be enye nusi dome nènyi tso dziwòlawo gbɔ. Ne domenyiŋusẽfianu si fia mɔ wò be nàwɔ G6PD enzyme la ƒe tɔtrɔ aɖe va la, enzyme sia si wowɔna le ŋutilãa me ƒe agbɔsɔsɔ dzi ɖena kpɔtɔna.
Gake nu vevitɔ le afisiae nye be menye amesiame si ŋu G6PD ƒe dɔmawɔmawɔ nyuie le lae axɔ dzesiawo o. Ame geɖe nɔa agbe si sɔ kuxi aɖeke manɔmee. Gake gotagomenu aɖewo (míeyɔa nusiawo be ‘nu siwo ʋãa ame’) ate ŋu ana dzesiawo nadze kpata.
Nusiwo hea G6PD ƒe dzesiwo vɛ
Nusiwo ʋãa ame siawo nana ŋutilãa dzia ‘free radicals’ mawo siwo gblẽa nu le ame ŋu siwo ŋu míeƒo nu tsoe la ƒe agbɔsɔsɔ ɖe edzi zi ɖeka. Ame si ŋu G6PD mele o mate ŋu aɖu nu gblẽnu siawo siwo le dzidzim ɖe edzi la dzi o. Ɣemaɣie ʋumenugbagbevi dzĩawo dzea gbagbã gɔme, eye dzesiwo dzena.
| Trigger Ƒomevi | Nuɖᴐɖᴐ |
|---|---|
| Nuɖuɖu aɖewo | Fava-kuwo koŋ. Woate ŋu ahe dzesiawo vɛ ne woɖu wo alo wogbɔ woƒe aŋɔ gɔ̃ hã. Wogayɔa nɔnɔme sia be ‘Favism’. |
| Atike aɖewo | Vevesesenutsitike aɖewo abe Aspirin, Acetaminophen (Paracetamol), Sulfa atike aɖewo, dɔlékuiwutike aɖewo kple asrãtikewoe nye vevitɔwo. Mègano atike aɖeke atikewɔlawo ƒe aɖaŋuɖoɖo manɔmee o. |
| Dɔlékui kple dɔlékuiwo ƒe dɔlélewo | Dɔlékui ɖesiaɖe, tso dzamezã dzi va ɖo dɔlékui sesẽwo dzi, ate ŋu ahe G6PD ƒe dzesiwo vɛ. |
G6PD ƒe anyimanɔmanɔ bɔ ɖe ŋutsuwo me wu nyɔnuwo, eye wòbɔ ɖe amesiwo tso Afrika, Asia, kple Mediterraneatɔwo dome.
Amekae wòle be woawɔ G6PD dodokpɔa?
Wò ɖɔkta ate ŋu aɖo aɖaŋu na wò be nàwɔ G6PD dodokpɔ (ʋudodokpɔ bɔbɔe aɖe), vevietɔ ne dzesi siwo gbɔna dometɔ aɖe le ŋuwò:
- Ðeɖiteameŋu kple gbɔdzɔgbɔdzɔ si womate ŋu aɖe o
- Ŋutilã si ƒe ŋutigbalẽ le ɣie
- Yagbɔgbɔ sesẽ alo ʋuʋudedi
- Dzi ƒe tsotso
- Ŋutilã kple ŋku ƒe ɣie (jaundice) .
- Aɖuɖɔ si do viviti (si ƒe amadede nye cola) .
- Akɔta alo ƒodo ƒe vevesese
- Tɔtɔ ƒe nɔnɔme si li fifia
Lé be na vidzĩ siwo wodzi yeyee etɔxɛe.
Enye nusi sɔ be vidzĩ si wodzi yeyee naxɔ ʋusɔgbɔdɔ. Gake ne enɔ anyi wu kwasiɖa eve , vidzĩa ƒe aɖuɖɔ do viviti, eye aɖuɖɔa do viviti la, ɖɔkta ate ŋu asusui be G6PD ƒe anyimanɔmanɔ le eŋu eye wòawɔ dodokpɔ sia.
Aleke míase dodokpɔa ƒe nyatakakaa gɔmee?
G6PD dodokpɔ me tsonu ate ŋu ato vovo vie tso dodokpɔxɔ ɖesiaɖe me, eyata wò ɖɔkta koe ate ŋu ana nyatakaka siwo de pɛpɛpɛ wu wò . Gake zi geɖe la, nu ƒomevi etɔ̃e dona tso eme.
- Nusi sɔ: G6PD enzyme sɔ gbɔ ɖe wò ŋutilã me. G6PD ƒe gbɔdzɔgbɔdzɔ mele ŋuwò o.
- Nusiwo mesɔ gbɔ o: Enzyme ƒe agbɔsɔsɔ le 10% va ɖo 60% le esi sɔ gbɔ. Zi geɖe la, ne dɔlékui aɖe le ame siawo ŋu alo wozã atike vɔ̃ɖi aɖe ko hafi dzesiawo dzena le wo ŋu.
- Gbɔdzɔgbɔdzɔ Sesẽ: Enzyme la le esi mede 10% le agbɔsɔsɔ si sɔ me o. Ʋusɔgbɔdɔ atraɖii ate ŋu anɔ ame siawo ŋu alo woƒe dzesiwo anɔ wo ŋu enuenu.
G6PD ƒe anyimanɔmanɔ ƒe atikewɔwɔ kple edzikpɔkpɔ
G6PD ƒe anyimanɔmanɔ menye dɔléle si woate ŋu ada keŋkeŋ o, elabena enye domenyiŋusẽfianu ƒe nɔnɔme. Gake ne èkpɔ egbɔ nyuie la, àte ŋu anɔ agbe si me lãmesẽ le kuxi aɖeke manɔmee .
Nu nyuitɔ si nàwɔe nye be nàƒo asa na ‘nu siwo hea dɔlélea vɛ’ siwo hea dzesiawo vɛ. Esiae nye atikewɔwɔ vevitɔ.
Ele be nàwɔ:
- Ƒo asa na fava-kuwo ɖuɖu keŋkeŋ.
- Ƒo asa na vevesesenutsitikewo abe Aspirin kple Acetaminophen (Paracetamol) nono wò ɖɔkta ƒe mɔɖeɖe manɔmee.
- Na wò ɖɔkta nanya be G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò hafi nàŋlɔ atike aɖeke na wò .
- Di atikewɔla enumake ne dɔlékui aɖe dze dziwò.
Ne wò dzesiawo mesẽ o la, wò ɖɔkta ate ŋu aŋlɔ folic acid kple iron-tikewo na wò. Ne wò ʋusɔgbɔdɔ nu sẽ la, ahiã be woaxɔ wò ɖe kɔdzi eye woado ʋu na wò alo woado oxygen-dɔdamɔnu na wò.
Nenɔ susu me na wò be antioxidants abe Vitamin E ene makpe ɖe nɔnɔme sia ŋu o.
Gbedasi si Wotsɔ Yi Aƒeme
- G6PD ƒe anyimanɔmanɔ nye domenyiŋusẽfianu ƒe dɔléle si bɔ si wotsɔna tsoa dzidzimewo me eye menye naneke si ŋu woavɔ̃ ɖo o.
- Dzesi aɖeke mele ame geɖe ŋu kura o. Dzesiawo dzena ne wodo go ‘nu siwo ʋãa ame’ abe fava beans, atike aɖewo, alo dɔlékuiwo ene.
- Dɔdzikpɔkpɔ vevitɔe nye be woaƒo asa na nusiwo hea dɔléle siawo vɛ.
- Ne G6PD ƒe dɔmawɔmawɔ nyuie le ŋuwò la, ele vevie ŋutɔ be nàna ɖɔkta ɖesiaɖe nanya hafi adi atike.
- Ne èkpɔ dzesiwo abe ɖeɖiteameŋu si gbɔ eme kpata, ŋutigbalẽ ƒe ɣie, alo aɖuɖɔ si do viviti ene la, yi ɖɔkta gbɔ enumake.
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