If you or someone you know is going to have surgery, you probably know that doctors use various methods to stop bleeding. Even if it's a cut, the bleeding needs to stop for it to heal quickly. Today we're going to talk about a special liquid medicine that's used to control bleeding during such surgery. It's called Thrombin. This isn't something you'd usually take home, but it's important to know about it.
Simply put, what is Thrombin?
Thrombin is a natural protein in our bodies that helps blood clot. Imagine that when you cut your hand, the bleeding stops after a while and a small blood clot forms at the site. Thrombin is one of the main factors that helps in that process.
Now, because of the advancement in medical science, this Thrombin has been made into a medicine. When this solution or gel is applied to the bleeding site during surgery, the blood clots very quickly and the bleeding stops. This is not a medicine that is injected into the blood vessels , but a topical one that is used only on the wound. This helps doctors to perform the surgery easily and safely.
Things you need to tell your doctor before giving this medicine
Your doctor will decide whether to give you this medicine. However, it is very important for you to inform the medical team in advance, as this will ensure your safety.
The most important thing is to be sure to tell us about any allergies you have.
Be especially careful about the following:
- Beef allergy: Some types of Thrombin are made from beef proteins. Therefore, if you have an allergy to beef products, you should definitely tell your doctor before surgery.
- Allergies to other medicines, foods, or things: Tell us if you are allergic to any other medicines, foods, or dyes.
- If you are pregnant or trying to get pregnant: If you are pregnant or planning to become pregnant in the near future, it is very important to inform your doctor.
- If you are a breastfeeding mother: If you are a breastfeeding mother, talk to your doctor about that as well.
How do you use this medicine?
This is not a medicine you should use on your own. Thrombin is only used by a doctor or a trained medical professional in a hospital or clinic . It is usually used in an operating theatre. So you do not need to take it home or store it.
If this medicine is used, especially on young children, it should be done with the necessary special care after discussing it with a pediatrician.
What if the dose of the medicine is increased?
Since this is administered under the supervision of a medical professional, the risk of an overdose is very low. However, if you suspect that you have taken too much of the medicine, notify the medical team immediately. They are usually prepared to provide the necessary treatment if this happens in a hospital setting.
If you need information about poisoning caused by the ingestion of any medicine or chemical, you can also call the National Poison Information Center located at the Colombo National Hospital .
What are the possible side effects of Thrombin?
Like any medicine, Thrombin can cause side effects in some people, although not everyone gets them. The table below provides a clearer picture of these.
| Type of side effect | Description |
|---|---|
| Things to tell your doctor or medical team immediately | |
| Allergic reactions | Things like skin rashes, severe itching, swelling of the face, lips, or tongue. |
| Difficulty breathing | If you feel like you're having trouble breathing. |
| High fever | A high fever lasting more than 24 hours. |
| Things that are usually not serious, but should be reported to the doctor if they persist | |
| Common fever | A slight fever. |
Are there any problems with other medications? (Drug Interactions)
Thrombin generally has fewer interactions with other medications because it is not an oral medication, but is used only on the wound.
However, it is best to tell your doctor about all the medications you are taking (prescribed by other doctors, over-the-counter medications, vitamins, traditional medicines, herbal products). It is also important to let your doctor know if you smoke or drink alcohol.
Take-Home Message
- Thrombin is a special medicine that is applied only to the wound to control bleeding during surgery.
- This is not a medicine you can take home. It is only used by medical professionals in the hospital.
- You should tell your doctor about any allergies you have, especially to beef, before surgery.
- Be sure to inform us if you are pregnant, planning to become pregnant, or are a breastfeeding mother.
- If you experience severe allergic symptoms such as facial swelling and difficulty breathing, notify the medical team immediately.
- If you have any questions about this medicine, don't hesitate to ask your doctor.


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