Loaʻa iā ʻoe kēia mau hōʻailona? E kamaʻilio kākou e pili ana i ka sarcoidosis!

Ke manaʻo nei ʻoe i kekahi manawa he mea ʻē i loko o kou kino, akā ʻaʻole hiki iā ʻoe ke ʻike pono i ke ʻano o ia mea? Aia kekahi mau maʻi e kū mai ana i loko o kou kino i kēlā me kēia manawa, akā inā ʻike maikaʻi ʻoe iā lākou, hiki iā ʻoe ke kāohi iā lākou. ʻO Sarcoidosis kekahi o ia ʻano maʻi. I kēia lā, e kamaʻilio maʻalahi mākou e pili ana i kēia, ma ke ʻano hiki iā ʻoe ke hoʻomaopopo.

He aha ka Sarcoidosis?

I ka ʻōlelo maʻalahi, ʻo ka sarcoidosis kahi kūlana e lilo ai ka ʻōnaehana pale o kou kino i mea hana nui a hana i nā puʻupuʻu liʻiliʻi ma nā wahi like ʻole o ke kino. Ua kapa ʻia kēia mau puʻupuʻu he granulomas . Pili nā hōʻailona i kahi e hana ai kēia mau granulomas a me ko lākou nui. I kekahi manawa ʻaʻohe hōʻailona iki, a hiki iā lākou ke ʻano mai ka ʻoluʻolu ʻole a hiki i nā hōʻailona koʻikoʻi. ʻO ka mea weliweli loa, i kekahi manawa hiki i kēia mau granulomas ke hana i ka ʻeha o nā ʻiʻo, i kapa ʻia ʻo fibrosis , hiki ke hōʻino mau i nā māmā, no ka laʻana.

Hiki i kēia mau granuloma ke hana ʻia ma nā wahi āpau o ke kino. Akā ʻo ka hapa nui o lākou e loaʻa ma nā māmā a me nā lymph node . Eia kekahi, hiki iā lākou ke hana i loko o ka ʻili, nā maka, a me nā ʻiʻo, e hana ana i nā hōʻailona.

He aha ka granuloma?

Hiki iā ʻoe ke noʻonoʻo i kahi kaua liʻiliʻi e hana nei i loko o kou kino? ʻO ka granuloma wale nō ia. Manaʻo kāu ʻōnaehana pale ua komo kahi mea ʻino i loko o kou kino. No laila, hōʻuluʻulu nā hunaola koko keʻokeʻo a puni kēlā mea ʻino, hoʻopuni iā ​​ia, a hoʻokaʻawale iā ia mai ke koena o kou kino. Ua like ia me ka pahele ʻana i kahi ʻenemi. Hoʻokumu kēia puʻupuʻu hunaola koko keʻokeʻo i kahi papa o nā ʻiʻo fibrous a puni ia. ʻO ia ke kumu e like ai ka granuloma me kahi puʻupuʻu liʻiliʻi ke hoʻopā ʻoe iā ia.

ʻO wai ka mea i hoʻopilikia nui ʻia e kēia kūlana?

Hiki i ka Sarcoidosis ke hoʻopilikia i kekahi, akā ʻoi aku ka nui o ka loaʻa ʻana o ia mea i kekahi poʻe. No ka laʻana, ʻoi aku ka maʻamau o ke ʻano i ka poʻe ʻeleʻele ma mua o ka poʻe keʻokeʻo. Hoʻopilikia iki ia i nā wahine ma mua o nā kāne. ʻIke pinepine ʻia ia i ka poʻe ma waena o 25 a me 40 mau makahiki .

ʻAʻole kēia he maʻi hoʻoilina. ʻO ia hoʻi, ʻaʻole ia he mea i hoʻoili pololei ʻia mai ka makuahine a i ka makuakāne. Eia nō naʻe, inā loaʻa kēia maʻi i kahi hoahānau pili o kou ʻohana (nā mākua, nā keiki, nā kaikaina), aia kekahi pilikia o ka loaʻa ʻana iā ia.

Ua manaʻo ʻia ʻo Sarcoidosis he maʻi laha ʻole . No ka laʻana, ma ʻAmelika Hui Pū ʻIa, aia ma lalo o ʻelua haneli tausani mau maʻi i kēlā me kēia manawa.

He aha nā hōʻailona o ka Sarcoidosis?

E like me kaʻu i ʻōlelo ai ma mua, pili nā hōʻailona i kahi o ke kino e hana ʻia ai nā granulomas. ʻIke ka hapa nui o ka poʻe i nā hōʻailona ma nā māmā. Eia nō naʻe, hiki ke ʻike ʻia kēia mau hōʻailona ma nā wahi āpau o ke kino, ma ka ʻili, ma nā maka, ma nā hono, ʻoiaʻiʻo. I kekahi manawa aia paha nā hōʻailona maʻamau, e like me ka manaʻo o ka nāwaliwali a me ka luhi, a i ʻole ʻaʻohe hōʻailona iki.

Nā hōʻailona i ʻike pinepine ʻia:

• kuni
• Luhi mau, luhi
• ʻEha hui
• ʻEha a nāwaliwali paha nā ʻiʻo
• Ke hou nei i ka pō
• Nā ʻōpū lymph pehu
• ʻO ka pohō kaumaha me ke kumu ʻole
• Hoʻokumu ʻia ʻana o nā pōhaku puʻupaʻa

Nā hōʻailona e pili ana i ka māmā:

• ʻŪhā (pinepine ka ʻūhā maloʻo)
• Ka paʻakikī o ka hanu ʻana, ka pōkole o ka hanu (dyspnea)
• ʻEha umauma
• ʻŌhūhū (wheezing) i ka wā e hanu ana

Nā hōʻailona e pili ana i ka maka:

• ʻIke makapō a nalowale paha ka ʻike (ma muli o nā kūlana e like me ka optic neuritis)
• ʻEha maka
• ʻUlaʻula a pehu paha o nā maka (nā kūlana e like me 'uveitis' a i ʻole 'conjunctivitis')
• ʻIke i ka mālamalama (hiki ʻole ke nānā aku i ke kukui)

Nā hōʻailona pili i ka ʻili:

• Nā puʻupuʻu ma lalo o ka ʻili a puni nā ʻeha a i ʻole nā ​​peʻa
• Nā kiko māmā a ʻeleʻele paha ma ka ʻili
• Nā puʻupuʻu ʻulaʻula-poni a i ʻole nā ​​​​​​ʻeha ma ka ihu a i ʻole nā ​​​​​​papālina (`lupus pernio`)
• ʻUlaʻula, palupalu nā puʻupuʻu ma ka ʻāpana ʻāʻī (erythema nodosum)

Nā hōʻailona e pili ana i ka puʻuwai:

• ʻEha umauma
• Ke manaʻo nei i kou puʻuwai e kuʻi ana i ke ʻano ʻē (palpitations)
• Ka maʻi ʻana o ka puʻuwai (arrhythmia)
• Ka hāʻule ʻana o ka puʻuwai
• Paʻakikī ka hanu ʻana

Nā hōʻailona e pili ana i ka ʻōnaehana nerve:

• Ka makewai pinepine a i ʻole ka mimi nui (Diabetes insipidus)
• Ka nāwaliwali a i ʻole ka maʻi lolo o nā ʻiʻo maka (Bell's palsy)
• ʻEha poʻo
• Nā hopu ʻana

He aha nā pae o ka sarcoidosis pulmonary?

ʻO Sarcoidosis, kahi maʻi e hoʻopilikia ana i nā māmā, i kekahi manawa ua wehewehe ʻia ma nā pae. Ua kapa ʻia kēia ʻo ka ʻōnaehana hoʻokaʻawale Siltzbach .

Akā he mea nui e hoʻomanaʻo: ʻAʻole pono kēia mau pae e hōʻike i ke koʻikoʻi o ka maʻi. ʻAʻole pono ʻoe e hele ma o lākou āpau. Ua hoʻokaʻawale ʻia lākou ma muli o ke ʻano o kou mau māmā ma kahi X-ray umauma. ʻO ia hoʻi, kahi i loaʻa ai nā granulomas.

Hiki i ke kanaka me ka sarcoidosis ke hele i mua a i hope ma waena o kēia mau pae, a i ʻole e nalowale loa nā granulomas. ʻO ke kahua hoʻihoʻi ʻole wale nō ka pae ʻehā. ʻO kēia ka wā e hōʻino mau ai nā māmā, i kapa ʻia ʻo pulmonary fibrosis.

• Pae 0:ʻAʻole hōʻike ka hoʻokolohua X-ray i nā hōʻailona o ka sarcoidosis i loko o nā māmā. ʻIke ʻia he maʻamau nā māmā a me nā lymph nodes.
• Pae 1: Aia nā granulomas i loko o nā lymph nodes wale nō.
• Pae 2: Aia nā granulomas i loko o nā lymph nodes a me nā māmā.
• Pae 3: Aia nā granulomas i loko o nā māmā wale nō.
• Pae 4: Hōʻike nā kukuna X-ray i ka fibrosis pulmonary, ʻo ia hoʻi ka ʻeha mau loa o nā māmā.

He aha ke kumu o ka sarcoidosis?

ʻAʻole ʻike ʻia ke kumu kikoʻī o kēia ʻano. Hōʻike ka noiʻi ua hana ʻia e ka hui pū ʻana o nā kumu genetic a me nā kumu kaiapuni. ʻO ke ʻano kēia, hiki i nā ʻōnaehana pale o kekahi poʻe ke pane nui i kekahi mau antigens , e like me ka bacteria a me nā virus. ʻOiai ua pili ka ʻōnaehana pale, ʻaʻole i manaʻo ʻia ka sarcoidosis he maʻi autoimmune .

ʻOiai ʻaʻole mākou maopopo pono i nā genes a me nā mea hoʻoulu e hui pū e hoʻokumu i kēia, he paʻakikī ke wānana i ka mea nāna e hoʻomohala.

He aha ka maʻi Löfgren?

ʻO ka maʻi Löfgren kahi hoʻomaka koke ʻana o ka sarcoidosis. Hōʻike ʻia ia e ka hui pū ʻana o nā hōʻailona e hoʻopilikia i kekahi mau ʻāpana o ke kino:

• ʻO ka rumatika ma kekahi mau hono.
• Kuni.
• Nā puʻupuʻu ʻulaʻula a palupalu ma ka ʻāpana ʻāʻī (erythema nodosum).
• Ka pehu ʻana o nā lymph nodes i loko o ka umauma.

ʻO ka nūhou maikaʻi, ʻo ka maʻi Löfgren e hoʻoholo pinepine ʻia i loko o 6 mau mahina a 2 mau makahiki.

Pehea e ʻike ʻia ai ka sarcoidosis?

Hoʻomaʻamaʻa pinepine ʻia ʻo Sarcoidosis e ke kauka nāna e nānā iā ʻoe ('hoʻokolokolo kino'), hana i nā hoʻokolohua kiʻi e like me ka X-ray umauma, a lawe i kahi laʻana liʻiliʻi o kahi granuloma kānalua no ka hoʻokolokolo ʻana (biopsy) . No ka mea hiki i ka maʻi ke loaʻa nā hōʻailona like me nā maʻi ʻē aʻe, hiki i kāu kauka ke kauoha i nā hoʻokolohua hou aʻe e kāpae i nā kūlana ʻē aʻe.

He aha nā hoʻokolohua diagnostics?

ʻO nā hoʻokolohua kiʻi a me nā biopsies nā hoʻokolohua maʻamau i hoʻohana ʻia e ʻike i ka sarcoidosis, akā hiki i kāu kauka ke kauoha i nā hoʻokolohua ʻē aʻe ma muli o kāu mau hōʻailona.

• Nā hoʻāʻo kiʻi: Hoʻohana kēia i nā mīkini kūikawā e kiʻi i nā kiʻi o nā mea i loko o kou kino. Hiki i kāu kauka ke kauoha i nā X-ray umauma, nā scan CT, a i ʻole MRI.
• Nā Biopsies:ʻOkoʻa ke ʻano o ka biopsy i hana ʻia ma muli o kahi i manaʻo ʻia ai ka granuloma. ʻAʻole nui ka hana ʻana i nā biopsies mai ka ʻili, ka conjunctiva, a me kekahi mau lymph nodes a hiki ke hana ʻia me ka ʻole o ka hana ʻana i kahi ʻoki nui.

I kekahi manawa, no ka loaʻa ʻana o kahi ʻāpana o ke kino mai nā māmā, pono ʻoe e hoʻohana i kahi ʻano hana paʻakikī. Hana ʻia kēia ma ke komo ʻana i nā ʻōmole liʻiliʻi, nā kāmela, a me nā mea hana biopsy ma o ka ihu a i ʻole ka puʻu, a i ʻole ma ka hana ʻana i kahi ʻoki liʻiliʻi. Nā Laʻana:

• ʻO ka hoʻohemo ʻana i ka nila maikaʻi transbronchial i alakaʻi ʻia e ka ultrasound endobronchial (EBUS-TBNA)
• ʻO ka biopsy transbronchial bronchoscopic
• ʻO `Mediastinoscopy` (He mau kaʻina hana lapaʻau paʻakikī kēia, a hana wale ʻia e ke kauka inā pono)

Nā hoʻokolohua ʻē aʻe:

• Nā hoʻāʻo hana puʻuwai: Nānā kēia i ka maikaʻi o ka hana ʻana o kou mau māmā. He mau hoʻāʻo maʻalahi kēia.
• Nā hoʻāʻo koko a me ka mimi ('Nā hoʻāʻo Lab'): E nānā pehea e hana ai nā ʻōpū ʻē aʻe, e like me ke akepaʻa a me nā puʻupaʻa.
• Electrocardiogram (EKG a i ʻole ECG): He hoʻāʻo maʻamau e nānā i ka hana uila o kou puʻuwai.
• Nā hoʻāʻo kiʻi nukelea: Hoʻokomo pū kēia me nā scan PET a me nā scan gallium. Hoʻohana kēia mau hoʻāʻo i kahi liʻiliʻi o ka mea radioactive e ʻimi ai i ka mumū i loko o ke kino.
• Hoʻāʻo i hoʻomaʻemaʻe ʻia i ka protein derivative (PPD): He hoʻāʻo ʻili maʻalahi kēia. Nānā ia no ka ʻike ʻia ʻana a i ʻole ka maʻi me ka maʻi puʻupuʻu (TB). He mea nui kēia no ka mea i kekahi manawa hiki i ka TB ke like me ka sarcoidosis.
• Hoʻokolokolo kukui slit: Nānā ke kauka i loko o kou maka e ʻike inā ʻo ka sarcoidosis ke kumu o nā pilikia maka.

Pehea e mālama ʻia ai ka sarcoidosis?

Hoʻomaʻamaʻa pinepine ʻia ʻo Sarcoidosis e kāohi i nā hōʻailona a pale i ka hōʻino ʻana o nā kino. E hoʻomanaʻo, hana ʻia nā granulomas e ka mumū i hoʻokumu ʻia e nā cell immune. No laila, pili ka lāʻau lapaʻau i nā lāʻau lapaʻau e hoʻololi a kāohi paha i ka ʻōnaehana immune. ʻOkoʻa ka lāʻau lapaʻau ma muli o kahi o ka granuloma i loko o ke kino.

ʻAʻohe lāʻau lapaʻau kūikawā no ka sarcoidosis. Akā, e hoʻomaikaʻi pinepine ia iā ia iho . Inā ʻaʻole hoʻopilikia loa nā hōʻailona a hoʻoweliweli paha i ke ola, i kekahi manawa ʻaʻole mālama koke ʻia ka sarcoidosis. Akā, e hana pū ʻoe a me kāu kauka e nānā i kāu mau hōʻailona.

He aha nā lāʻau lapaʻau no ka sarcoidosis?

Hana kēia mau lāʻau lapaʻau ma ka hoʻololi ʻana a i ʻole ka kaohi ʻana i ka ʻōnaehana pale a me ka hōʻemi ʻana i ka mumū. ʻO kekahi o nā lāʻau lapaʻau i hoʻohana pinepine ʻia:

• Nā Corticosteroids:Nā lāʻau lapaʻau e like me ka prednisone a me ka cortisone. Hoʻemi kēia i ka mumū i loko o ke kino. Loaʻa lākou ma ke ʻano he mau pila e ale ai, ma ke ʻano he mea hoʻoheheʻe e pīpī i loko o ka waha, a i ʻole ma ke ʻano he kirīmi topical (no ka ʻili a i ʻole nā ​​maka).
• Nā Immunosuppressants: Kōkua kēia i ka pale ʻana i ka ʻōnaehana pale mai ka hōʻino ʻana i nā kino a me ke kumu ʻana o ka mumū. ʻO Methotrexate kahi ʻano lāʻau i hoʻohana pinepine ʻia no ka sarcoidosis.
• Nā antibodies anti-tumor necrosis factor-alpha (anti-TNF-alpha antibodies): Nā lāʻau lapaʻau e like me ka infliximab. Hana kēia mau mea ma ke ālai ʻana i kahi kemika kikoʻī i loko o ka ʻōnaehana pale e hōʻemi i ka mumū. Hāʻawi ʻia kēia mau lāʻau lapaʻau e ke kauka ma ke ʻano he infusion (e like me ka saline solution) i loko o kahi aa.
• Nā Lāʻau Anti-Inflammatory Nonsteroidal (NSAID): Hāʻawi kēia i ka hōʻoluʻolu manawa pōkole mai nā hōʻailona i hoʻokumu ʻia e ka mumū, akā ʻaʻole lākou e kuhikuhi pinepine ʻia no ka wā lōʻihi.

He aha nā pilikia/nā hopena ʻaoʻao o ka lāʻau lapaʻau?

Hiki i nā Corticosteroids ke hoʻonui i kou pilikia o ka maʻi. Hiki iā lākou ke hana i kekahi mau hopena ʻaoʻao. ʻO nā hiʻohiʻona:

• Ka nui loa.
• ʻAʻole hiki ke hiamoe.
• ʻAkika.
• ʻO ka hoʻomohala ʻana i ka maʻi diabetes i nā poʻe i maʻi i ka maʻi diabetes.
• Ke koko kiʻekiʻe.
• ʻO ka glaucoma.
• Nā katarata.
• Ka lahilahi o nā iwi (Osteoporosis).
• Kaumaha a me ka paʻakikī i ka hoʻokele ʻana i nā manaʻo.
• ʻIli e palaho maʻalahi.

No kēia mau kumu, ʻōlelo wale nā ​​​​kauka i ka lāʻau lapaʻau no ka sarcoidosis inā ʻoi aku ka maikaʻi o nā pono ma mua o nā pilikia.

Pehea ka wikiwiki o koʻu ʻoluʻolu ma hope o ka lāʻau lapaʻau?

Hiki ke hala i kekahi mau pule a i kekahi mau mahina no ka hoʻomaikaʻi ʻana o nā hōʻailona ma hope o ka hoʻomaka ʻana o ka lāʻau no ka sarcoidosis. E nānā kāu kauka iā ʻoe a e hana paha i nā hoʻokolohua hahai e ʻike ai inā e holo pono ana ka lāʻau.

He aha nā meaʻai maikaʻi ʻole e ʻai ai i ka wā e loaʻa ai iā ʻoe ka sarcoidosis?

Manaʻo kekahi mau noiʻi e hiki i kekahi mau ʻano meaʻai ke hōʻemi i ka mumū i loko o ke kino. ʻO ka ʻai ʻana i nā meaʻai mea kanu e like me nā mea kanu a me nā huaʻai , ka palena ʻana i ka ʻiʻo a me ka tīhi, a me ka hōʻemi ʻana i nā kalapona e like me ke kō a me ka berena e kōkua paha i kāu mau hōʻailona sarcoidosis. Akā e ʻoluʻolu e nīnau i kāu kauka ma mua o ka hoʻomaka ʻana i kahi meaʻai hou.

Hiki ke pale ʻia ka sarcoidosis?

No ka mea, ʻaʻole ʻike ʻia ke kumu pololei, ʻaʻohe ala e pale aku ai i ka sarcoidosis a i ʻole e hōʻemi i ka pilikia o ka loaʻa ʻana. Eia nō naʻe, ʻo ka lawe ʻana i nā lāʻau lapaʻau e like me ke kauoha a kāu kauka hiki ke kōkua i ka hōʻemi ʻana i ka hōʻino ʻana i nā ʻōpū i hoʻokumu ʻia e nā granulomas.

He aha ka manaʻolana no ka sarcoidosis?

ʻOkoʻa ke koʻikoʻi o ka Sarcoidosis. No ka hapa nui o nā kānaka, he kūlana manawa pōkole ia e hoʻōla iā ia iho a i ʻole me ka mālama ʻana. No kekahi poʻe, hiki ke lilo i maʻi lōʻihi (he 'maʻi mau') a hōʻeha mau loa.

E noʻonoʻo i kēia: Ma kahi o ʻelua hapakolu o ka poʻe me ka sarcoidosis e hoʻōla piha ʻia (ʻo ia hoʻi, e komo ka maʻi i ka 'hoʻōla ʻana') i loko o ʻelua a ʻekolu mau makahiki. ʻOi aku ka maikaʻi o ka poʻe me ka maʻi Löfgren i ʻōlelo ʻia ma mua, i loko o 6 mau mahina a 2 mau makahiki.

ʻO ka poʻe e loaʻa mau ana i ka sarcoidosis ma hope o ʻekolu mau makahiki, ʻoi aku ka nui o ka loaʻa ʻana o ka maʻi lōʻihi. Eia nō naʻe, ʻoiai i ka poʻe me ka sarcoidosis lōʻihi, he 10% a 20% wale nō o ka poʻe e loaʻa ka hōʻino mau loa o nā kino. ʻO ka pilikia maʻamau ka ʻeha o ka māmā.

ʻO ka hapa nui o nā maʻi sarcoidosis e ola i kahi ola maʻamau. He hapa liʻiliʻi wale nō (1% - 5%) e make ana. No laila, ʻaʻohe mea e hopohopo ai, he kūlana hiki ke mālama ʻia kēia.

Pehea e mālama ai iaʻu iho i koʻu wā e noho ana me ka sarcoidosis?

ʻO ka mea maikaʻi loa hiki iā ʻoe ke hana, ʻo ia ke hahai i nā ʻōlelo a kāu kauka. E nānā mau i kāu mau hōʻailona no nā loli. E lawe i kāu lāʻau lapaʻau e like me ke kauoha. He mea nui hoʻi e noho mālie.

Āhea wau e ʻike ai i ke kauka?

Inā loaʻa iā ʻoe nā hōʻailona hou, inā lilo kāu mau hōʻailona i mea hoʻopilikia, a inā ʻoe e lawe ana i ka lāʻau lapaʻau a pilikia ʻoe me nā hopena ʻaoʻao, e ʻike koke a kamaʻilio paha me kāu kauka.

He aha nā nīnau e pono iaʻu e nīnau aku i kaʻu kauka?

He mea kōkua paha ke nīnau i kēia mau nīnau ke kipa aku ʻoe i kāu kauka:

• He ʻoi aku ka maikaʻi iaʻu ke ʻimi i ka lāʻau lapaʻau a i ʻole ke nānā ʻana i kaʻu mau hōʻailona?
• ʻEhia ka lōʻihi e pono ai e hoʻomaikaʻi i nā hōʻailona?
• Pehea e ʻike ai inā e holo pono ana kaʻu lāʻau lapaʻau?
• Pono anei iaʻu e hana i kekahi mau hoʻololi i koʻu nohona?
• Āhea wau e hele hou mai ai e ʻike iā ʻoe?

I ka hōʻuluʻulu manaʻo (Leka Lawe-Home)

He maʻi laha ʻole ka Sarcoidosis e hiki ai ke hoʻoulu i nā ʻano hōʻailona like ʻole. Mai hopohopo, ʻo ka hapa nui o ka manawa e nalo wale ia ma kāna iho a i ʻole me ka mālama ʻana. ʻOiai hiki ke lōʻihi, hiki ke mālama maikaʻi ʻia me ka lāʻau lapaʻau a me ke aʻo lapaʻau. E hoʻomanaʻo, i kekahi mau hihia he ʻoi aku ka maikaʻi o ka nānā wale ʻana i kāu mau hōʻailona me ka ʻole o ka mālama ʻana. Hiki iā ʻoe a me kāu kauka ke hoʻoholo i ka mea maikaʻi loa iā ʻoe. No laila, e noho ikaika a e hahai i ka ʻōlelo aʻo a kāu kauka.

ʻO Sarcoidosis, granuloma, ʻōnaehana pale, maʻi māmā, maʻi ʻili, maʻi maka, maʻi puʻuwai, Sarcoidosis, granuloma, ʻōnaehana pale, maʻi māmā, maʻi ʻili, maʻi maka, maʻi puʻuwai