Aia kekahi o kou ʻohana, ʻo kou makuahine paha, kou makuakāne, a i ʻole kahi mea aloha, i loaʻa i ka maʻi ʻo Parkinson? A laila ʻike paha ʻoe i kekahi manawa e lilo koke ko lākou kino i ʻoʻoleʻa , hoʻomaka lākou e haʻalulu, a ʻaʻole hiki iā lākou ke hana i kekahi mea. Ua like ia me ke kaʻa e kū koke ana. I kēia lā, ke kamaʻilio nei mākou e pili ana i kahi inikini kūikawā i hoʻohana ʻia e hāʻawi i ka hoʻomaha wikiwiki mai kēia mau mea i kapa ʻia ʻo "off-periods." ʻO ia ka inikini Apomorphine.
He aha ka ʻApomorphine?
I ka ʻōlelo maʻalahi, ʻo Apomorphine kahi lāʻau lapaʻau i hoʻohana ʻia e mālama i nā hōʻailona o ka maʻi Parkinson. Hana like ia me kahi kemika i kapa ʻia ʻo dopamine i loko o ko kākou lolo. Ua ʻike anei ʻoe ua hana ʻia ka maʻi Parkinson e ka nalowale ʻana o nā cell i loko o ko kākou lolo e hana ana i kēia kemika i kapa ʻia ʻo dopamine. Kōkua kēia dopamine i ka hoʻomalu ʻana i nā neʻe a me ka hoʻonohonoho ʻana o ko kākou kino.
No laila, ke lawa ʻole ka dopamine, ʻike ʻia nā hōʻailona e like me ka ʻoʻoleʻa a me ka haʻalulu. Hana ka inikini apomorphine e like me ka dopamine, e hoʻopiha ana i kēlā hemahema no kekahi manawa, a kōkua i ka hoʻihoʻi ʻana i nā neʻe ʻana o ke kino. Loaʻa pinepine kēia ma ka mākeke ma lalo o ka inoa ʻo Apokyn .
E noʻonoʻo ua waiho ka maʻi Parkinson i kou kino i paʻa, e like me ka puka paʻa me ke kī ʻole. Ua like ka inikini apomorphine me ke kī kūikawā e wehe ana i kēlā puka. Hoʻihoʻi koke ia i kou kino i ka maʻamau. Akā hiki ke hoʻohana ʻia no nā mea ʻē aʻe, no laila inā he mau nīnau kāu, e nīnau i kāu kauka.
Nā mea e haʻi aku i kāu kauka ma mua o ka hoʻohana ʻana i kēia lāʻau lapaʻau
Ma mua o ka hāʻawi ʻana iā ʻoe i kēia lāʻau lapaʻau, pono kāu kauka e ʻike i kou mōʻaukala olakino piha. ʻO kēia no ka mea pono kekahi mau kūlana i ka mālama kūikawā i ka wā e hoʻohana ai i kēia lāʻau lapaʻau. E hōʻoia e haʻi i kāu kauka e pili ana i kekahi o kēia mau mea:
- Inā loaʻa iā ʻoe ka hānō.
- Inā he ʻano maʻamau kou e hiamoe pinepine i ke ao a hiamoe koke paha.
- Inā he mea inu pinepine ʻoe.
- Inā ua loaʻa iā ʻoe kahi hahau ma mua.
- Inā he maʻi puʻuwai kou .
- Inā he moʻolelo kou o ka hāʻule mau ʻana i ka pilikia .
- Inā he puʻuwai kūpono ʻole a i ʻole kahi loli o ka rhythm.
- Inā he maʻi kou i ka puʻupaʻa a i ʻole ke akepaʻa.
- Inā he haʻahaʻa kou koko .
- Inā he mau pilikia olakino noʻonoʻo kou (e like me ke kaumaha).
- Inā ua loaʻa iā ʻoe kahi hopena maʻi i ka apomorphine, sulfites, a i ʻole kekahi lāʻau lapaʻau ʻē aʻe, meaʻai, a mea hoʻoluʻu paha.
- Inā hāpai ʻoe a i ʻole e hoʻāʻo nei e hāpai .
- Inā he makuahine ʻoe e hānai waiū ana .
He mea nui loa ka hāʻawi pololei ʻana i kēia ʻike i kāu kauka no kou palekana.
Pehea e hoʻohana pono ai i ka lāʻau pale?
He inikini subcutaneous kēia. Ke hoʻomaka ʻoe e lawe i kēia lāʻau lapaʻau, e hāʻawi kāu kauka a kahu maʻi paha iā ʻoe i nā kuhikuhi kikoʻī no ka hoʻomākaukau ʻana i ka inikini a pehea e inikini ai iā ʻoe iho. He mea nui loa ia e hahai pololei i kēia mau kuhikuhi.
- E hoʻohana e like me ka mea a kāu kauka e ʻōlelo ai: Mai hoʻohana ʻoi aku ma mua o ka nui i kuhikuhi ʻia a i ʻole ka alapine (pinepine).
- Mai ho'ōki koke i ka lawe ʻana i kēia lāʻau lapaʻau: Mai ho'ōki i ka lawe ʻana i kēia lāʻau lapaʻau ke ʻole ke kuhikuhi ʻia e kāu kauka. ʻO ka hoʻōki koke ʻana hiki ke hana i nā hopena ʻaoʻao koʻikoʻi a hoʻonui i kou kūlana.
- E hoʻolei pono i nā nila a me nā syringe: Mai hoʻolei i nā nila a me nā syringe i hoʻohana ʻia i loko o ka ʻōpala. Pono e waiho ʻia i loko o kahi pahu ʻoi kūikawā i hāʻawi ʻia. Inā ʻaʻohe āu, hiki iā ʻoe ke noi i kāu kauka no hoʻokahi.
- E heluhelu i ka pepa kuhikuhi: E heluhelu pono i ka pepa kuhikuhi e hele mai ana me kēia lāʻau lapaʻau. Inā he mau nīnau kāu, e nīnau i kāu kauka.
He aha inā wau e lawe i ka overdose?
Inā manaʻo ʻoe ua lawe ʻoe i nā lāʻau lapaʻau ma mua o kou manaʻo, e hele koke i ka Halemai Pilikia (ETU) kokoke loa a kāhea aku i ke Kikowaena ʻIke ʻAi ʻona Lahui ma ka Halemai Lahui ʻo Colombo .
Ua kuhikuhi ʻia kēia lāʻau lapaʻau nou wale nō. No laila, mai kaʻana like me kekahi.
He aha nā lāʻau lapaʻau ʻē aʻe e pono ʻole e hoʻohana pū ʻia me kēia lāʻau lapaʻau?
Hiki i kekahi mau lāʻau lapaʻau ke launa pū me ka apomorphine a hoʻoulu i nā pilikia koʻikoʻi. No laila, pono ʻoe e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei, me nā huaora, nā lāʻau lapaʻau lāʻau, a me nā mea hoʻohui.
| Māhele lāʻau lapaʻau | Ka wehewehe a me nā laʻana |
|---|---|
| Nā lāʻau lapaʻau e pono ʻole ke lawe ʻia | |
| ʻO kekahi mau lāʻau lapaʻau no ka nausea/luaʻi | Eia kekahi laʻana: dolasetron, granisetron, ondansetron, palonosetron |
| Nā lāʻau lapaʻau ʻē aʻe | ʻO Dronedarone, Ketoconazole, Levoketoconazole, Pimozide, Thioridazine |
| Nā mea e hoʻohana me ke akahele/nā pilina hiki ke hana ʻia | |
| ʻAila | Hoʻopilikia nui ʻia nā hopena ʻaoʻao e ka hoʻonui ʻana. |
| Lāʻau lapaʻau no ka hopohopo a i ʻole ka hiamoe | Eia kekahi laʻana: ʻO nā Benzodiazepines e like me alprazolam, diazepam, lorazepam |
| ʻO kekahi mau lāʻau lapaʻau koko | E nīnau pono i kāu kauka e pili ana i kēia. |
| ʻO ka nitroglycerin | Hiki i ke koko ke hāʻule haʻahaʻa loa (e wehewehe ʻia kēia ma lalo). |
| Nā lāʻau lapaʻau ʻē aʻe | Haloperidol, Metoclopramide, Opioids, nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ai i ka puʻuwai puʻuwai, Phenothiazines. |
ʻAʻole i piha kēia papa inoa, no laila ʻoi aku ka maikaʻi o ka haʻi ʻana i kāu kauka e pili ana i nā mea āpau āu e lawe ai.
Nā mea e hoʻomanaʻo ai i ka wā e lawe ai i kēia lāʻau pale
Aia kekahi mau mea e noʻonoʻo ai e pili ana i kou palekana i ka wā e hoʻohana ai i kēia lāʻau.
E ʻike pinepine i ke kauka.
E ʻike pinepine i kāu kauka e nānā i kou kūlana a ʻike inā e hoʻomaikaʻi a ʻoi aku paha ka ʻino o kāu mau hōʻailona. Inā ʻaʻole e hoʻomaikaʻi a ʻoi aku paha ka ʻino o kāu mau hōʻailona, e haʻi i kāu kauka .
Ka luaʻi a me ka luaʻi
Hiki i kēia lāʻau lapaʻau ke hoʻoulu i ka nausea a me ka luaʻi ʻana, i kekahi manawa hiki ke koʻikoʻi loa. E kuhikuhi kāu kauka i kahi lāʻau lapaʻau ʻē aʻe no kēia. Mai lawe i kekahi lāʻau lapaʻau no ka nausea ma kāu iho. ʻO kēia no ka mea hiki i kekahi mau lāʻau lapaʻau no ka nausea ke launa pū me ka apomorphine.
Ka hiamoe a me ka hoʻokele kaʻa ʻana
Hiki i kēia lāʻau lapaʻau ke hoʻopilikia i kou hoʻonohonoho ʻana a me ka manawa pane. No laila, a hiki i kou ʻike pono ʻana i ke ʻano o kēia lāʻau lapaʻau iā ʻoe , e pale i ka hana ʻana i nā hana e pono ai ka makaʻala, e like me ka hoʻokele kaʻa a i ʻole ka hoʻohana ʻana i nā mīkini. Eia kekahi, e kū mālie i luna ke kū koke ʻoe, a i ʻole ke ala ʻoe mai kahi noho. A i ʻole, hiki iā ʻoe ke manaʻo i ka poniuniu a me ke poʻo māmā. ʻOi aku ka nui o kēia pilikia inā inu ʻoe i ka waiʻona.
He mea nui! I ka wā e lawe ai i kēia lāʻau lapaʻau, hiki i kekahi poʻe ke hiamoe koke me ka ʻole o ka ʻōlelo aʻo . Hiki ke hana kēia i ka wā e hoʻokele ana, e kamaʻilio ana, a i ʻole e ʻai ana. Inā hana kēia iā ʻoe, e haʻi koke aku i kāu kauka.
Ka hopena me ka nitroglycerin
Inā ʻoe e lawe ana i ka nitroglycerin no ka maʻi puʻuwai, pono ʻoe e makaʻala loa. ʻO ka lawe ʻana me kēia lāʻau lapaʻau hiki ke hoʻohaʻahaʻa loa i kou koko. Hiki i kēia ke kumu i ka poniuniu, ka māʻule ʻana, a me ka hāʻule ʻana paha.
No laila, inā pono ʻoe e lawe i ka nitroglycerin,
1. ʻO ka mua, e moe i lalo.
2. A laila e kau i ka papa ma lalo o kou alelo.
3. E moe i lalo no 45 mau minuke ma ka liʻiliʻi.
He aha nā hopena ʻaoʻao e hiki mai ana?
E like me nā lāʻau lapaʻau āpau, hiki i ka apomorphine ke hana i nā hopena ʻaoʻao. He koʻikoʻi kekahi, he mea maʻamau kekahi.
| Ka hopena ʻaoʻao | Wehewehena |
|---|---|
| Nā hopena ʻaoʻao koʻikoʻi e pono e hōʻike koke ʻia i ke kauka | |
| Nā hopena alerike koʻikoʻi (nā hopena alerike a i ʻole angioedema) | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā maka, nā lehelehe, ke alelo, nā lima a i ʻole nā wāwae, paʻakikī ke ale a i ʻole ka hanu ʻana. |
| ʻEha umauma (Angina) | Ke ʻeha nei, ka paʻa, a i ʻole ke kaomi ma ka umauma, ka ʻāʻī, ke kua, a i ʻole nā lima. |
| Hiamoe koke | Ka hiamoe ʻana me ka ʻole o ka ʻike maka ʻana i ka wā e hana ana i ke ao. |
| Nā manaʻo hoʻokalakupua | Ke ʻike ʻana a i ʻole ka lohe ʻana i nā mea i ʻike ʻole ʻia. |
| Nā hōʻailona o ka hōʻeha puʻuwai | ʻEha ka umauma, poʻohiwi, lima a i ʻole ka ʻauwae, ka luaʻi, ka paʻakikī o ka hanu ʻana, ka hou anu, ka poniuniu. |
| Nā loli i ka helu o ka puʻuwai | Ka puʻuwai wikiwiki a ʻano ʻē paha, ka poniuniu, ka maule ʻana, ka ʻeha o ka umauma. |
| ʻAʻai koko hemolytic | Luhi kūikawā, poniuniu, ʻeha poʻo, paʻakikī ka hanu ʻana, mimi ʻeleʻele, melemele o ka ʻili a i ʻole nā maka. |
| Nā ʻano hana maʻamau ʻole | He makemake hiki ʻole ke kāohi ʻia e piliwaiwai, ʻai nui, komo i ka hana moekolohe, a i ʻole e hoʻolilo kālā me ke kumu ʻole. |
| Nā hopena ʻaoʻao ʻaʻole i koʻikoʻi pinepine, akā pono e hōʻike ʻia i ke kauka inā hoʻomau lākou | |
| Pōʻino, hiamoe | Hiki ke hana pinepine ʻia kēia mau mea. |
| Ka luaʻi, ka luaʻi | He mea maʻamau ia i nā pae mua o ka hoʻomaka ʻana o ka lāʻau lapaʻau. |
| Ihu wai a i ʻole ka ihu paʻa | Hiki ke manaʻo ʻia e like me nā hōʻailona o ke anu. |
| Ka pehu ʻana o nā kuʻekuʻe wāwae, nā lima, a i ʻole nā wāwae | Hiki ke loaʻa ma muli o ka paʻa ʻana o ka wai i loko o ke kino. |
Inā loaʻa iā ʻoe kekahi mau hopena ʻē aʻe i helu ʻole ʻia ma kēia papa inoa, e ʻoluʻolu e hoʻomaopopo i kāu kauka.
Pehea ʻoe e mālama ai a hoʻolei aku i ka lāʻau lapaʻau?
- E mālama i kahi hiki ʻole i nā keiki a me nā holoholona ke kiʻi aku.
- E mālama ma ka mahana o ka lumi (ma waena o 20-25 kekelē Celsius).
- Mai hoʻohana i ka lāʻau lapaʻau i pau ka lā.
- I ke kiola ʻana i nā lāʻau lapaʻau i hoʻohana ʻole ʻia a i ʻole nā lāʻau lapaʻau i pau ka manawa, e nīnau i kāu kauka e pili ana i kahi ʻano hana palekana.
Leka Lawe-Home
- ʻO ka inikini Apomorphine kahi lāʻau lapaʻau e hāʻawi ana i ka hōʻoluʻolu wikiwiki mai ka hoʻomaka koke ʻana o ka paʻakikī a me nā haʻalulu ("off-periods") i ka maʻi o Parkinson.
- E haʻi mau i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe nei a me nā kūlana olakino ʻē aʻe āu e loaʻa nei.
- E pale i ka hoʻokele kaʻa a i ʻole ka hoʻohana ʻana i nā mīkini a hiki i kou ʻike ʻana i ke ʻano o ka hopena o kēia lāʻau lapaʻau iā ʻoe. E hoʻomanaʻo e hiamoe koke paha ʻoe.
- E ʻimi koke i ke kōkua lapaʻau inā loaʻa iā ʻoe nā hopena ʻino e like me ka ʻeha o ka umauma, nā maʻi alerika koʻikoʻi, a i ʻole nā loli o ka puʻuwai.
- E hoʻolei mau i nā nila a me nā syringe i hoʻohana ʻia me ka palekana i loko o kahi "pahu ʻoi" kūikawā.
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