Ua ʻōlelo ʻia anei ʻoe a i ʻole kekahi āu i ʻike ai e ke kauka e lawe i ka "mea hoʻomāmā koko"? Ua makaʻu iki paha ʻoe i kou lohe ʻana i kēlā inoa. Ua manaʻo paha ʻoe, "Auē, e hoʻomāmā koʻu koko?" Akā, he mau lāʻau lapaʻau koʻikoʻi kēia e hiki ke hoʻōla i nā ola inā hoʻohana pono ʻia. I kēia lā, ke kamaʻilio nei mākou e pili ana i kekahi papa lāʻau lapaʻau hou a holomua. ʻO lākou ʻo Factor Xa Inhibitors.
I ka ʻōlelo maʻalahi, he aha kēia mau Factor Xa Inhibitors?
ʻO nā Factor Xa Inhibitors kahi papa o nā lāʻau lapaʻau e pale ai i kou koko mai ke kāpili ʻana i ke koko. Kāhea mākou iā lākou he "nā mea hoʻomāmā koko" ma nā huaʻōlelo maʻamau. Akā kapa nā kauka iā lākou he "Direct Oral Anticoagulants" a i ʻole "DOACs". Hiki ke hoʻohana ʻia no ka wā lōʻihi e mālama i kahi ʻūpā koko i hana mua ʻia, a me ka pale ʻana i nā ʻūpā koko e hiki mai ana.
Aia kekahi mau ʻano lāʻau lapaʻau nui ʻē aʻe e hāʻule ana i loko o kēia māhele. Ua kuhikuhi paha kāu kauka i kekahi o kēia mau mea nāu.
- ʻApixaban
- ʻO Betrixaban
- ʻEdoxaban
- ʻO Rivaroxaban
- Fondaparinux (ʻAʻole kēia he pila. He inikini intravenous ia)
He aha nā kūlana e hoʻohana ʻia ai kēia lāʻau lapaʻau?
Hoʻohana ʻia kēia ʻano lāʻau lapaʻau e mālama a pale aku i kekahi mau maʻi koʻikoʻi. E noʻonoʻo i kahi kīʻaha koko i loko o ko kākou kino e like me kahi paipu e lawe ana i ka wai. Inā paʻa kahi ʻūpā koko i kahi o kēia paipu, hiki iā ia ke hana i nā pilikia nui. ʻO ia ka mea a kēia lāʻau lapaʻau e kōkua ai e pale aku.
Hiki iā ʻoe ke loaʻa kahi manaʻo maikaʻi e pili ana i kēia mai ka papa ma lalo nei.
| Ke kūlana e mālama ʻia/kāohi ʻia nei | He wehewehe maʻalahi |
|---|---|
| Ka hōʻemi ʻana i ka pilikia o ka hahau ʻana | Hiki i kekahi poʻe me ka puʻuwai puʻuwai kūpono ʻole (atrial fibrillation) ke hoʻomohala i nā ʻūpā koko i loko o nā aʻa e alakaʻi ana i ka lolo a hana i kahi hahau. Hoʻemi kēia lāʻau lapaʻau i kēlā pilikia. |
| Ke mālama nei i ka Deep Vein Thrombosis (DVT) | He kūlana kēia kahi e hana ai nā ʻūpā koko i loko o nā aa koko hohonu i loko o ke kino, ʻoi aku hoʻi ma nā wāwae. Kōkua kēia lāʻau lapaʻau i ka hoʻoheheʻe ʻana i kēlā mau ʻūpā. |
| Ka Lapaʻau ʻana o ka Pulmonary Embolism (PE) | Hiki mai kēia kūlana ke haki kahi ʻūpā koko ma ka wāwae a paʻa i loko o kahi aa koko i loko o nā māmā. He mea weliweli loa kēia. He lāʻau lapaʻau kēia no kēlā. |
| Ke pale ʻana i ka Venous Thromboembolism (VTE) | ʻO kēia ka inoa i hāʻawi ʻia i ka DVT a me ka PE pū kekahi. Mālama kēia lāʻau lapaʻau i kēia mau kūlana mai ka hoʻi hou ʻana mai. |
| Ka hōʻemi ʻana i ka pilikia o ka maʻi puʻuwai a me nā maʻi kīʻaha koko | He mea pono nō hoʻi kēia lāʻau lapaʻau no ka poʻe me ka maʻi ʻaʻa coronary a me ka maʻi ʻaʻa peripheral. |
| Ma hope o ke ʻoki kino nui | Ma hope o ke ʻoki ʻana i ka ʻūhā a i ʻole ke kuli, ʻoi aku kou pilikia o ka loaʻa ʻana o nā ʻūpā koko no ka mea ua paʻa ʻoe i kahi moe. Hāʻawi ʻia kēia lāʻau lapaʻau e pale aku i kēia. |
He aha ka ʻokoʻa o kēia lāʻau lapaʻau mai Warfarin?
Ua lohe paha ʻoe i ka lāʻau Warfarin. He lāʻau maikaʻi loa nō hoʻi ia e pale ai i nā ʻūpā koko a ua hoʻohana ʻia no nā makahiki he nui. Akā ʻo ka pilikia nui loa no kekahi e lawe ana iā Warfarin, ʻo ia ka loaʻa ʻana o nā hoʻāʻo koko pinepine . ʻO ia hoʻi, e hele i ka haukapila i hoʻokahi manawa i ka mahina, ʻelua paha i ka pule, e hāʻawi i ke koko a loaʻa kahi hoʻāʻo e ana i ka manawa e pono ai ke koko e ʻūpā. Ma muli o kēlā mau hopena, e hoʻonui a hoʻemi paha ke kauka i ka nui o ka lāʻau.
ʻO kekahi o nā pono nui o Factor Xa Inhibitors ʻaʻole lākou e koi pinepine i nā hoʻāʻo koko, kahi e hoʻemi nui ai i ka pilikia no ka mea maʻi.
Pehea e hana ai kēia lāʻau lapaʻau i loko o ke kino?
He mea hoihoi loa kēia. E noʻonoʻo i ke kūkulu ʻia ʻana o kahi ʻūpā koko e like me ke kaʻina hana hōʻuluʻulu ma kahi hale hana. Nui nā ʻanuʻu e pili ana. Hui pū nā protein e hana i ke ʻūpā koko.
He protein ʻo Factor Xa he mea hana koʻikoʻi loa ia i kēlā "kaʻina hana hōʻuluʻulu." ʻO ka hana a kēia lāʻau lapaʻau, ʻo ia ke hoʻopilikia i ka hana o kēlā protein i kapa ʻia ʻo Factor Xa.Ua like ia me ka hoʻomaha ʻana mai ka hana no kekahi manawa. A laila hoʻi ke kaʻina hana holoʻokoʻa o ke koko i ka maʻamau. ʻO ia hoʻi, ua pau ke kūkulu ʻia ʻana o nā ʻōpū koko pono ʻole. Ua maopopo iaʻu?
Pehea ka lōʻihi e pono ai ʻoe e lawe i kēia lāʻau lapaʻau?
Aia kēia i ke kumu āu e lawe nei i ka lāʻau lapaʻau. He ʻokoʻa ia mai kēlā kanaka a kēia kanaka.
- Inā he puʻuwai kūpono ʻole kou (atrial fibrillation): Pono paha ʻoe e lawe i kēia lāʻau lapaʻau no ke koena o kou ola.
- Inā he ʻūpē koko kou i loko o kahi aa koko (VTE): ʻO ka maʻamau ma waena o 3 a me 6 mau mahina.
- Inā he ʻūpē koko kou ma kou wāwae (DVT) a i ʻole ka māmā (PE): E hala ana ma kahi o 6 mahina.
- Inā ma hope o ke ʻoki kino pani kuli: He 12 mau lā wale nō ma hope o ke ʻoki kino.
- Ma hope o ke ʻoki ʻana i ka ʻūhā: E hala ana ma kahi o 35 mau lā ma hope o ke ʻoki ʻana.
ʻO ka mea nui loa, ʻo ia ka lawe ʻana i kāu lāʻau lapaʻau e like me ka ʻōlelo a kāu kauka. Mai hoʻōki i ka lawe ʻana i kāu lāʻau lapaʻau me ka ʻole o ke noi ʻana aku i kāu kauka.
He aha nā pilikia a me nā hopena ʻaoʻao o kēia mau lāʻau lapaʻau?
E like me nā lāʻau lapaʻau āpau, aia kekahi mau pilikia. Ma muli o ko lākou pale ʻana i ke kāpili ʻana o ke koko, ʻo ka pilikia nui me kēia mau lāʻau lapaʻau , ʻoi aku ka nui o ke kahe ʻana o ke koko ma mua o ka maʻamau .
- Ke kahe koko nui: He mea kākaʻikahi loa, hiki ke kahe koko i loko o ka lolo a i ʻole ma nā wahi e like me ka ʻōpū a i ʻole nā naʻau. Hiki ke paʻakikī ke kāohi i kēia mau mea. Eia nō naʻe, aia i kēia manawa nā lāʻau lapaʻau kūikawā i kapa ʻia ʻo "reversal agents" (e.g. andexanet alfa) hiki ke hoʻohuli i nā hopena o kēia mau lāʻau. Hoʻohana nā kauka i kēia mau mea i nā hihia o ke kahe koko e hoʻoweliweli ana i ke ola.
- Nā hopena ʻaoʻao liʻiliʻi:
- ʻOiai inā loaʻa iā ʻoe kahi ʻeha liʻiliʻi i kou kino, e ʻike pinepine paha ʻoe i nā kiko koko (nā palapū) .
- Hiki i kekahi poʻe ke loaʻa i kahi ʻulaʻula ʻili .
ʻO ka mea nui, ʻaʻole kēia pilikia i kū hoʻokahi i kēia mau lāʻau lapaʻau. Loaʻa i kēlā me kēia lāʻau hoʻokahe koko kēia pilikia. No laila, mai makaʻu. Akā, he mea nui loa ia e makaʻala.
Pehea ʻoe e makaʻala ai i ka wā e lawe ai i ka lāʻau lapaʻau?
Inā ʻoe e lawe ana i kēia lāʻau lapaʻau, he mea nui loa ia e pale iā ʻoe iho mai nā ulia a me nā ʻeha i ka hiki. ʻOiai kahi ʻoki liʻiliʻi hiki ke paʻakikī ke hoʻōki i ke kahe ʻana o ke koko. Eia kekahi mau ʻōlelo aʻoaʻo maʻalahi e kōkua iā ʻoe.
| He aha e hana ai | No ke aha he mea nui kēlā? |
|---|---|
| E akahele loa i ka hoʻohana ʻana i nā mea ʻoi (pahi, ʻokiʻoki). | Inā ʻoki ʻoe i kou lima, hiki ke paʻakikī ke hoʻōki i ke kahe ʻana o ke koko. E akahele me nā pahi i ka holoi ʻana i nā kīʻaha. |
| Inā ʻoe e kahi, e hoʻohana i ka pahi ʻumiʻumi uila ma kahi o ka pahi ʻumiʻumi me ka pahi. | Hiki ke hoʻemi ʻia ka pilikia o ka ʻoki ʻana iā ʻoe iho me ka pahi. |
| E komo i nā mīkina lima a me nā kāmaʻa i ka wā e hana ana i loko o ka māla. | ʻOiai he ʻeha mai kahi mea e like me ka ʻō a me ke kākalaioa paha ke kumu o ke kahe koko nui. |
| E makaʻala i nā pilikia paheʻe a hāʻule paha (nā moena, nā uea ma ka papahele) i loko o ka hale. | Hiki ke hoʻoweliweli nā ʻeha mai ka hāʻule ʻana, ʻoiai inā paʻi ʻoe i kou poʻo. |
I ka manawa hea e pono ai iaʻu ke ʻike i ke kauka?
Inā ʻike ʻoe i kekahi o kēia mau hōʻailona i ka wā e lawe ana i kēia lāʻau lapaʻau, e kāhea koke aku i kāu kauka, a i ʻole e hele i ka lumi pilikia haukapila kokoke loa (ETU).
- Ke kahe koko nui ʻaʻole hiki ke hoʻōki: Inā ʻaʻole hiki ke hoʻōki ʻia ke kahe koko mai kahi ʻeha, ihu, waha, a i ʻole nā ʻāʻī.
- He hāʻule ʻana: Inā hāʻule ʻoe i kekahi wahi, ʻoiai inā paʻi ʻoe i kou poʻo, e kahe ana ke koko i loko ʻoiai inā ʻaʻohe ʻeha i ʻike ʻia.
- Inā he koko i loko o ka ʻōpala (ʻeleʻele a ʻulaʻula paha ka ʻōpala).
- Inā ʻoe e luaʻi i ke koko (e like me ke kofe lepo a ʻulaʻula paha).
- ʻEha nui ka umauma, ke poʻo, a i ʻole ka ʻōpū.
- Paʻakikī ka hanu ʻana.
- He ʻōhū koke.
He kōkua nui kēia lāʻau lapaʻau no nā poʻe he nui no ka mea ʻaʻole pono lākou e hoʻāʻo pinepine ʻia ko lākou koko e like me Warfarin. Eia naʻe, ʻaʻole kūpono kēia lāʻau lapaʻau no nā mea āpau. E kamaʻilio me kāu kauka e hoʻoholo i ka lāʻau lapaʻau maikaʻi loa iā ʻoe. ʻAʻohe mea he aha ka lāʻau lapaʻau āu e lawe ai, he mea nui e hahai pololei i nā ʻōlelo a kāu kauka.
Leka Lawe-Home
- He papa lāʻau lapaʻau hou a kūpono nā Factor Xa Inhibitors e pale ai i ke kāpili ʻana o ke koko.
- Ke hoʻohālikelike ʻia me nā lāʻau lapaʻau kahiko e like me Warfarin, ʻaʻole pono ʻoe e hana i nā hoʻāʻo koko pinepine i ka wā e lawe ai i kēia. He mea maʻalahi nui kēlā.
- ʻO ka pilikia nui o kēia mau lāʻau lapaʻau, ʻo ia ke kahe nui ʻana o ke koko, no laila he mea nui loa ia e pale iā ʻoe iho mai nā ʻeha.
- Mai hoʻomaka, hoʻōki, a hoʻololi paha i ka nui o kekahi lāʻau lapaʻau me ka ʻole o ke aʻo a kāu kauka.
- Inā loaʻa iā ʻoe ke kahe koko ʻē aʻe a i ʻole nā hōʻailona weliweli ʻē aʻe, e ʻimi koke i ke kōkua lapaʻau.
💬 Comments (0)
ʻAʻohe manaʻo i kau ʻia. Hoʻohui i kāu manaʻo ma ʻaneʻi no ka manawa mua.
Hoʻohui i kāu manaʻo