Ua lohe paha ʻoe i ka 'Germ Cell Tumor'? Malia paha he mea weliweli iki ke kani ʻana o ka inoa, akā mai hopohopo. I kēia lā e kamaʻilio mākou e pili ana i ia mea ma ke ʻano maʻalahi e hiki ai iā ʻoe ke hoʻomaopopo. No ka mea, he mea nui loa ka makaʻala i kēia mau mea, ʻoiai hiki iā lākou ke ulu i kekahi manawa i nā keiki ʻōpio a me nā mākua ʻōpio.
He aha kēia mau puʻupuʻu germ cell?
I ka ʻōlelo maʻalahi, ʻo ka puʻupuʻu germ cell he puʻupuʻu e ulu ana mai kā mākou mau cell hānau, i kapa ʻia ʻo 'germ cells'. ʻO ka huaʻōlelo "germ" ʻo ia hoʻi "e ulu" a i ʻole "e oʻo." I kēia manawa, i loko o ke kaikamahine, e lilo kēia mau cell germ i mau 'hua' ma hope. I loko o ke keikikāne, e lilo kēia i 'sperm'. No laila, ʻo kēia mau puʻupuʻu germ cell ka mea e ulu nui ai ma nā wahi i hana ʻia ai nā hua, ʻo ia hoʻi nā 'ovaries', a me kahi i hana ʻia ai ka sperm, ʻo ia hoʻi nā 'testicles'.
Eia nō naʻe, i kekahi manawa hiki i kēia mau puʻupuʻu ke ulu ma nā wahi ʻē aʻe o ke kino ma waho aʻe o nā ovaries a me nā testicles. No ka laʻana, hiki iā lākou ke ulu ma nā wahi e like me ka ʻōpū, ka umauma, ke kua i lalo, ka iwi huelo, a me ka lolo. ʻO nā puʻupuʻu e ulu ana ma nā wahi ʻē aʻe e like me kēia ua kapa ʻia he mau puʻupuʻu extragonadal . ʻO ia hoʻi, nā puʻupuʻu e ulu ana ma waho o nā glands hānau.
ʻO ka mea nui loa, ʻike pinepine ʻia kēia mau ʻōʻō germ cell i nā keiki ʻōpio, nā ʻōpio, a me nā mākua ʻōpio .
Aia kekahi ʻano o nā puʻupuʻu germ cell?
ʻAe, aia ʻelua ʻano o nā puʻupuʻu germ cell. Hiki i kekahi ke lilo i malignant , ʻo ia hoʻi he cancerous lākou. ʻO kekahi ʻano he benign . Hiki i nā ʻano ʻelua o nā puʻupuʻu ke ulu nui. Eia nō naʻe, ʻo nā puʻupuʻu germ cell cancerous wale nō ke laha i nā ʻāpana ʻē aʻe o ke kino. Ke laha lākou (metastasized), hiki iā lākou ke hōʻino i ko mākou mau kino o loko a ʻoi aku ka paʻakikī o ka mālama ʻana.
E nānā kākou i nā ʻano nui o nā tumors cell germ:
ʻO Teratoma
He ʻano hua kūikawā loa kēia. Hiki i kēia mau hua ke loaʻa nā ʻiʻo e like me nā niho, ka lauoho, nā ʻiʻo, a me ka iwi. E noʻonoʻo iā ia e like me kahi hua i hana ʻia me nā ʻano mea like ʻole. Hiki i kēia ke 'ʻōpiopio' a 'ʻōpiopio' paha.
- ʻO nā teratoma makua , i kekahi manawa i kapa ʻia ʻo dermoid cysts , ʻo ia ke ʻano maʻamau o ka puʻupuʻu germ cell e ulu ana i loko o nā ovaries. ʻO ka hapa nui o ka manawa, ʻaʻole lākou he maʻi kanesa.
- He maʻi kanesa nā teratoma i ʻōpiopio , a ulu koke lākou.
Nā ʻōpū Yolk Sac a i ʻole nā ʻōpū Endodermal Sinus
Aia i loko o kēia mau hua nā pūnaewele e like me nā pūnaewele i loko o kahi embryo e ulu ana.He mau maʻi ʻino kēia a hiki ke laha koke i nā lymph node a me nā ʻōpū ʻē aʻe. ʻO nā puʻupuʻu yolk sac ke ʻano maʻamau o ka puʻupuʻu germ cell cancerous i nā keiki ʻōpio.
ʻO Germinoma
He ʻano puʻupuʻu kanesa nō hoʻi kēia. Hiki iā ia ke ulu i loko o nā ovaries a i ʻole nā testicles. Eia nō naʻe, ʻike pinepine ʻia ia ma ka lolo a me ke kaula spinal (ʻōnaehana nerve waena). Ke ulu ia i loko o nā ovaries, kapa ʻia ʻo ia he dysgerminoma , a ke ulu ia i loko o nā testicles, kapa ʻia ʻo ia he seminoma .
ʻO ke kanesa o nā pūnaewele embryonal
He puʻupuʻu germ cell cancerous kakaʻikahi kēia. I kekahi manawa hiki ke kū hoʻokahi, akā ʻike pinepine ʻia me ka hui pū ʻana me nā ʻano puʻupuʻu ʻē aʻe, e hana ana i kahi puʻupuʻu germ cell mixed .
Polyembryoma
Aia i loko o kēia mau puʻupuʻu nā ʻāpana e like me nā embryos. He ʻano puʻupuʻu kanesa laha ʻole kēia, e ulu wikiwiki ana. ʻO ka hapa pinepine, hana ʻia kēia mau puʻupuʻu me nā puʻupuʻu germ cell ʻē aʻe.
ʻO ke kanikoma kōrio
Hoʻokumu ʻia kēia mau puʻupuʻu mai nā pūnaewele e hana ana i ka placenta i ka wā hāpai. E like me kāu e ʻike ai, ʻo ka placenta ke kino e kōkua i ka makuahine a me ka pēpē e hoʻololi i nā meaʻai. He puʻupuʻu germ cell cancerous kakaikahi nō hoʻi ka Choriocarcinoma. ʻOiai hiki ke ulu i loko o nā ovaries a i ʻole nā testicles, ulu pinepine ia i loko o ka uterus. ʻO ka mea kūikawā e pili ana iā ia, hiki iā ia ke laha i ka fetus a me ka makuahine.
Nā ʻōpū o ke kelepona huaola i hui pū ʻia
He mau puʻupuʻu kēia e hana ʻia ke hui pū ʻia ʻelua a ʻoi aku paha nā ʻano puʻupuʻu germ cell cancerous. ʻO ka ʻoiaʻiʻo, ua hui pū ʻia nā puʻupuʻu germ cell he nui e like me kēia.
He aha ka ʻokoʻa ma waena o nā puʻupuʻu seminoma a me nā puʻupuʻu non-seminoma?
Ua māhele ʻia nā ʻōpū germ cell i nā kāne, ʻoiai ke kanesa testicular, i ʻelua ʻano: seminomas a me non-seminomas . He mau ʻōpū kanesa nā mea ʻelua.
- Seminomas: ʻOi aku ka lohi o ka ulu ʻana a me ka laha ʻana o kēia mau mea ma mua o nā non-seminomas.
- Nā Non-seminomas: ʻOi aku ka wikiwiki o ka ulu ʻana a me ka laha ʻana o kēia mau mea ma mua o nā seminomas. No kēia māhele o nā non-seminomas nā yolk sac tumors, nā embryonal cell carcinomas, nā choriocarcinomas, a me nā teratomas.
Pehea ka maʻamau o kēia mau ʻōʻō cell germ?
He mea kākaʻikahi nā puʻupuʻu cell germ i nā keiki ʻōpio. He 3.5% o nā maʻi kanesa āpau i nā keiki lākou. Eia nō naʻe, ʻike pinepine ʻia lākou i nā ʻōpio a me nā mākua ʻōpio. He 13.9% o nā maʻi kanesa āpau i nā poʻe ma waena o 15 a me 19 mau makahiki lākou.
ʻO wai ka mea i hoʻopilikia nui ʻia e kēia kūlana?
ʻOiai hiki i kekahi ke hoʻomohala i nā ʻōpū germ cell,ʻO nā pēpē, nā kamaliʻi liʻiliʻi, nā ʻōpio, a me nā mākua ʻōpio ka poʻe i maʻalahi loa. ʻOkoʻa ka nui o kēia mau maʻi me ka makahiki. No ka laʻana, he mea maʻamau lākou mai ka wā kamaliʻi a hiki i ka 4 mau makahiki, a laila e emi iki ana, a laila e hoʻonui hou ʻia i ka wā ʻōpio.
- ʻO nā puʻupuʻu ovarian germ cell: ʻO kēia ka mea maʻamau i nā kaikamahine ma waena o 10 a me 14 mau makahiki. Eia nō naʻe, hiki iā lākou ke ulu i loko o ka poʻe i ko lākou mau makahiki 20 a me 30. ʻO ka teratoma makua (ʻaʻole maʻamau he cancerous) ke ʻano o ka puʻupuʻu germ cell i ʻike pinepine ʻia.
- Nā puʻupuʻu germ cell testicular: ʻO kēia ʻano ka 75% o nā maʻi kanesa testicular i nā keiki, a me 90% o nā maʻi kanesa testicular āpau. ʻOi aku ka maʻamau o lākou i nā keiki ma lalo o 4 mau makahiki a i nā kāne ma waena o 15 a me 35 mau makahiki.
- Nā puʻupuʻu cell germ extragonadal: ʻO kēia mau puʻupuʻu no 40% a 50% o nā puʻupuʻu cell germ āpau i ʻike ʻia i nā keiki ma lalo o 4 mau makahiki. Eia nō naʻe, hiki iā lākou ke loaʻa i nā keiki a me nā ʻōpio. I nā pēpē a me nā kamaliʻi ʻōpio, loaʻa pinepine lākou ma ka sacrum a i ʻole coccyx. I nā ʻōpio a me nā mākua ʻōpio, loaʻa pinepine lākou ma ka mediastinum.
- ʻO nā puʻupuʻu cell germ o ka lolo: ʻOiai he mea kakaikahi kēia, ʻike pinepine ʻia lākou i nā poʻe ma waena o 11 a me 30 mau makahiki.
He aha nā hōʻailona o kahi puʻupuʻu germ cell?
ʻOkoʻa nā hōʻailona o kēia puʻupuʻu ma muli o ka nui o ka puʻupuʻu a me kona wahi ma ke kino.
Nā hōʻailona o nā cysts ovarian
ʻAʻole nā puʻupuʻu cell germ e ulu ana i loko o nā ovaries e hōʻike mau i nā hōʻailona. No ka laʻana, ʻaʻole paha e hōʻike kahi teratoma makua i kekahi mau hōʻailona a hiki i ka nui o ia mea e hōʻeha ai i ka ʻōpū. ʻIke pinepine ʻia lākou i ka wā o ka ultrasound scan e ʻimi ai i ke kumu o ka ʻeha o ka ʻōpū haʻahaʻa.
Hiki ke like nā hōʻailona me kēia:
- ʻO ka ʻoluʻolu ʻole a i ʻole ka ʻeha ma ka ʻōpū lalo.
- Ke manaʻo nei i kahi puʻu ʻeha ma ka ovary.
- Pehu, pehu.
- ʻEha ʻōpū (e like me ka appendicitis ).
- Ke kahe koko ʻana o ka ʻōpū ma ke ʻano kūpono ʻole.
- Ka luaʻi.
Nā hōʻailona o nā cysts testicular
ʻO nā hōʻailona o nā ʻōpū germ cell e ulu ana i loko o nā testicles ua like ia me nā hōʻailona o ke kanesa testicular.
Eia nā ʻano:
- He puʻu paʻakikī a paʻa i loko o ka testicle e hoʻonui mālie ana (ʻeha paha a ʻaʻole paha).
- Ka manaʻo o ka ʻeha a i ʻole ke kaumaha ma ka scrotum.
- ʻEha ʻōpū a ʻeha paha o ka ʻūhā.
- ʻAno ʻē o ka testicle.
- ʻEha hope.
Nā hōʻailona o nā ʻōpū e kū mai ana ma nā wahi ʻē aʻe (extragonadal)
He puʻu ma nā puʻupuʻu o kāu keiki a i ʻole ma waenakonu o ko lākou umaumaInā he, he teratoma paha ia. ʻOkoʻa nā hōʻailona ʻē aʻe ma muli o kahi o ka puʻupuʻu.
- Ka paʻakikī o ka hanu ʻana (inā pili i ka māmā).
- Ka nāwaliwali o nā wāwae (inā ma ke kua i lalo).
- Ka paʻakikī i ka mimi a me ka defecating (inā pili ka pilikia i ka pelvis).
- He pehu ko ke keiki a he ʻeha nui a palupalu paha ma ka ʻōpū.
Hoʻopuka kekahi mau ʻōʻō cell germ i nā hormones hānau. Hiki i kēia ke hōʻike i nā keiki i nā hōʻailona o ka wā ʻōpiopio i ka wā mua a i ʻole ka ulu ʻana o ka moekolohe maʻamau. Hiki i nā kaikamahine ke ulu i nā umauma, ka lauoho pubic, a me ka menstruation mua. Hiki i nā keikikāne ke ulu i nā umauma (gynecomastia).
He aha ke kumu o kēia mau puʻupuʻu cell germ?
ʻO ka maʻamau, hoʻokumu ʻia kēia mau cell germ i ka wā e ulu ana kahi embryo kanaka. A laila neʻe kēia mau cell i nā ovaries a i ʻole nā testicles o ka embryo, kahi e lilo ai lākou i mau cell hua manu a i ʻole nā cell sperm.
Akā, i loko o nā puʻupuʻu germ cell, ʻaʻole i ulu piha kēia mau cell i nā hua a i ʻole sperm. Akā, māhele like ʻole kēia mau cell germ a hana i nā puʻupuʻu i loko o nā ovaries a i ʻole nā testicles. I loko o nā 'extragonadal tumors' a mākou i kamaʻilio ai ma mua, hele kēia mau cell germ i nā wahi ʻē i ke kino - nā wahi e like me ka umauma, ka lolo, ka ʻōpū, ke kua haʻahaʻa, nā puʻupuʻu - a hana i nā puʻupuʻu ma laila.
ʻO kaʻoiaʻiʻo, ʻaʻole i ʻike pono nā kānaka noiʻi i ke kumu e hana ai kēia mau cell germ.
He aha nā kumu pilikia?
Hiki paha iā ʻoe ke loaʻa i kahi puʻupuʻu germ cell inā ua loaʻa i kekahi o kou ʻohana i hoʻokahi ma mua, a inā he mau maʻi kou.
Eia nā kūlana e like me kēia:
- ʻO ka loaʻa ʻana o nā testicles i mālama ʻole ʻia, ʻaʻole i iho i lalo ( cryptorchidism ).
- He kūlana i kapa ʻia ʻo Turner syndrome .
- He kūlana i kapa ʻia ʻo Klinefelter syndrome .
ʻO kēia nā kūlana genetic a i ʻole nā kūlana ulu i ʻike ʻia e nā kauka.
Pehea e ʻike ʻia ai nā ʻōpū o nā cell germ? (Diagnosis)
E hana mua kāu kauka i kahi hoʻokolohua kino a nīnau e pili ana i kāu mau hōʻailona. A laila, hiki iā lākou ke hana i hoʻokahi a ʻoi aku paha o nā hoʻokolohua aʻe e hoʻoholo ai inā he puʻupuʻu germ cell kou:
- CT scan: Pili kēia i ka lawe ʻana i nā kiʻi X-ray he nui o loko o kou kino a me ka hoʻohana ʻana i kahi kamepiula e hana i kahi kiʻi ʻekolu-dimensional (`3D`) o nā iwi a me nā ʻiʻo palupalu. Hiki i kahi CT scan o ka umauma, ka ʻōpū, a i ʻole ka pelvis ke kōkua i ka ʻimi ʻana i ka puʻupuʻu.
- MRI: Hoʻohana kēia i kahi magnet a me nā nalu lekiō e hana i kahi kiʻi kamepiula o nā iwi a me nā ʻiʻo palupalu o ke kino. E like me ka CT scan, hiki i ka MRI ke hōʻike i kahi o ka puʻupuʻu.
- Ultrasound:Hoʻohana kēia i nā nalu kani e hana i nā kiʻi o loko o ke kino. Hōʻike ka ultrasound i ka nui o ka puʻupuʻu paʻa a me ka nui o ka wai (`cystic`). Kōkua kēia ʻike e hoʻoholo inā he puʻupuʻu germ cell a he wai wale nō paha (`cyst`).
- ʻIke PET: Hoʻohana kēia i kahi kemika kūikawā (kahi `tracer`) e ʻike i nā wahi o nā hunaola kanesa i loko o ke kino. Hiki i kahi ʻike PET ke ʻike inā ua laha ke kanesa.
- Nā scan iwi: Pili kēia i ka hoʻokomo ʻana i kahi kala kūikawā i loko o ke kino, e ʻae ana iā ia e komo i loko o nā iwi, a laila lawe i nā kiʻi X-ray. Kōkua kēia kala i ka hōʻike ʻana i nā mea ʻē a hiki ke kōkua i ka hoʻoholo ʻana inā ua pālahalaha kahi puʻupuʻu i nā iwi.
- Nā hoʻāʻo koko: Hiki i kāu kauka ke lawe i kahi hāpana koko e nānā i nā pae o kekahi mau enzymes, protein, a i ʻole hormones i loko o kou koko. ʻO nā pae kiʻekiʻe o nā mea e like me ke kanaka chorionic gonadotropin (hCG) , alpha-fetoprotein (AFP) , a me ka lactate dehydrogenase hiki ke lilo i hōʻailona o kekahi mau ʻano o nā puʻupuʻu germ cell.
- Biopsy: Pili kēia i ka lawe ʻana i kahi ʻāpana liʻiliʻi o ka ʻiʻo mai ka puʻupuʻu a hoʻouna iā ia i kahi keʻena hoʻokolohua no ka hoʻāʻo ʻana. E nānā kahi pathologist , he kauka loea i ka nānā ʻana i nā ʻiʻo, i ka hāpana ma lalo o kahi microscope e hoʻoholo ai inā he puʻupuʻu germ cell ia.
He mea nui: Inā paha he maʻi kanesa kou puʻupuʻu, hiki i kāu kauka ke hoʻoholo e wehe i ke kino holoʻokoʻa. No ka laʻana, ʻo ke kaʻina hana maʻamau no ka ʻike ʻana i ke kanesa testicular, ʻo ia ka wehe ʻana i ka testicle holoʻokoʻa ( radical inguinal orchiectomy ). ʻO ka wehe ʻana i ka testicle e hiki ai i kāu kauka ke kālailai i nā ʻiʻo a hana i ke ʻoki ʻana ma ke ʻano he lāʻau lapaʻau.
Pehea e mālama ʻia ai nā ʻōpū germ cell?
Aia kekahi mau koho lapaʻau. Na kāu kauka e hoʻoholo i ka lāʻau lapaʻau maikaʻi loa ma muli o ke ʻano, ka nui, kahi o ka puʻupuʻu, a me kou olakino holoʻokoʻa.
- ʻO ke ʻoki kino: ʻO ke ʻoki kino ka lāʻau lapaʻau nui no nā ʻōpū germ cell. I ke ʻano o nā ʻōpū ovarian, hiki ke wehe ʻia ka ʻōpū wale nō ( ovarian cystectomy ), a i ʻole hiki ke wehe ʻia ka ovary holoʻokoʻa a me ka fallopian tube ( salpingo-oophorectomy ). I ke ʻano o ka maʻi ʻaʻai testicular, wehe ʻia ka testicle e loaʻa ana ka ʻōpū.
- Kemoterapia: ʻO kēia ka hāʻawi ʻana iā ʻoe i nā lāʻau lapaʻau e pepehi i nā hunaola kanesa a i ʻole e hoʻōki iā lākou mai ka māhele ʻana. Inā ʻaʻole hiki i kāu kauka ke wehe palekana i ka puʻupuʻu, a inā ua pālahalaha ia i nā ʻāpana ʻē aʻe o kou kino, hiki ke hāʻawi ʻia iā ʻoe i ka chemotherapy. Ma hope o ke ʻoki ʻana, hāʻawi ʻia ka chemotherapy e pepehi i nā hunaola kanesa i waiho ʻia, ʻoiai inā ʻaʻole i ʻike ʻia ma kahi scan. Hoʻohana ʻia ka Chemoterapia no ka hapa nui o nā ʻano puʻupuʻu cell germ.He ʻano lapaʻau holomua loa.
- Lapaʻau radiation: Pili kēia i ka hoʻohana ʻana i nā kukuna X-ikehu kiʻekiʻe e luku i nā hunaola kanesa. Pane maikaʻi kekahi ʻano ʻōpū germ cell i ka lapaʻau radiation.
Hiki ke ho'ōla loa ʻia kahi puʻupuʻu germ cell?
He maikaʻi loa ka wānana, a i ʻole ka manaʻolana o ka hoʻōla ʻana, no ka hapa nui o nā ʻōpū germ cell. Hoʻōla pinepine ʻia ka maʻi inā wehe loa ʻia ka ʻōpū. No ka laʻana, he 95% ka nui o ke ola ʻana o ka maʻi kanesa testicular ma hope o ka mālama ʻana. He 93% ka nui o ke ola ʻana o nā ʻōpū germ cell ovarian. ʻO ka nui o ka hoʻōla ʻana o nā ʻōpū germ cell i nā keiki ma waena o 82% a me 90%.
Eia nō naʻe, pili kēia mau hopena i kekahi mau mea kūikawā iā ʻoe. ʻO kēia mau mea:
- kou mau makahiki.
- ʻAno puʻupuʻu o nā cell germ.
- ʻO ka wahi a me ka nui o ka puʻupuʻu.
- ʻO ka mamao i laha ai ke kanesa.
- Ka pane a ka puʻupuʻu i ka lāʻau lapaʻau.
No laila, he mea nui loa e kamaʻilio me kāu kauka e pili ana i ka hopena o kāu hōʻailona i kāu mau hopena.
Nā nīnau koʻikoʻi e nīnau aku i kāu kauka
Hiki iā ʻoe ke nīnau i kēia mau nīnau e hoʻomaopopo maikaʻi i kāu hōʻailona:
- He maʻi ʻaʻai (malignant) anei koʻu puʻupuʻu?
- Pehea ka wikiwiki o ka ulu ʻana (ka ikaika) o koʻu puʻupuʻu?
- Ua laha anei ke kanesa?
- He aha nā lāʻau lapaʻau āu e paipai nei?
- He aha nā hopena ʻaoʻao e hiki ke loaʻa mai ka lāʻau lapaʻau?
- He aha nā hopena e hiki ke pili i kēlā me kēia koho lapaʻau?
- He aha nā hoʻokolohua e pono ai iaʻu e hana e nānā i ka pono o ka lāʻau lapaʻau?
- ʻEhia mau manawa e pono ai iaʻu e hele mai no nā manawa hoʻopaʻa e nānā i kaʻu puʻupuʻu / pane i ka lāʻau lapaʻau?
ʻO ka mea hope loa, nā mea e hoʻomanaʻo ai (Leka Lawe-Home)
ʻO ka puʻupuʻu germ cell kahi puʻupuʻu e ulu ana mai nā cell hānau. Hiki i kāu kauka ke wehewehe iā ʻoe pehea e pili ai kēia hōʻailona iā ʻoe a i ʻole kāu keiki. He paʻakikī iki nā puʻupuʻu germ cell. Aia kāu mau hōʻailona a me kou prognosis i nā kumu he nui, nā mea a pau a kāu kauka e kūkākūkā ai me ʻoe.
ʻO ka nūhou maikaʻi, ʻo ka hapa nui o nā ʻōpū germ cell e pane maikaʻi i ka lāʻau lapaʻau. E like me nā ʻōpū āpau (ʻoi aku hoʻi nā ʻōpū kanesa), ʻo ka wikiwiki o kou ʻike ʻana a hoʻomaka i ka lāʻau lapaʻau, ʻoi aku ka maikaʻi o kāu hopena. No laila, inā loaʻa iā ʻoe kahi puʻupuʻu, pehu, a ʻeha paha, he mea naʻauao ke ʻimi i ka ʻōlelo aʻoaʻo lapaʻau ma mua o ka hoʻowahāwahā ʻana iā ia.
ʻO nā puʻupuʻu cell germ, maʻi ʻaʻai, teratoma, puʻupuʻu yolk sac, germinoma, maʻi ʻaʻai ovarian, maʻi ʻaʻai testicular
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