Ua ʻike anei ʻoe he "pūʻali koa" nui ko kou kino e pale aku iā ʻoe mai nā maʻi? Kāhea mākou i kēia ʻōnaehana pale. ʻO ka hana a kēia pūʻali koa, ʻo ia ke mālama iā mākou i ke olakino ma ke kaua ʻana i nā ʻenemi e like me nā germs, nā virus, a me nā cell cancer e hele mai ana mai waho. Akā i kekahi manawa, pono kēia pūʻali koa i kahi kōkua iki. ʻAʻole lawa ka ikaika o ka pūʻali koa, a i ʻole hoʻomaka ka pūʻali koa e hana ma waho o ka mana. ʻO ia ka manawa e hiki ai i kahi papa kūikawā o nā lāʻau lapaʻau i kapa ʻia ʻo `(Immunomodulators)` ke kōkua iā mākou.
I ka ʻōlelo maʻalahi, he aha kēia mau Immunomodulators?
ʻO nā Immunomodulators kahi ʻano lāʻau lapaʻau e "hoʻololi" a "hoʻololi" paha i ka hana o kāu ʻōnaehana pale. E noʻonoʻo i kāu ʻōnaehana pale e like me ka mana leo ma kahi lekiō. I kekahi mau maʻi, ua haʻahaʻa loa kēia leo, ʻo ia hoʻi ua nāwaliwali ka ʻōnaehana pale. I nā maʻi ʻē aʻe, ua kiʻekiʻe loa kēia leo, ʻo ia hoʻi ua hana nui ka ʻōnaehana pale.
No laila, ʻo ka mea a nā `(Immunomodulators)` e hana ai, ʻo ia ke hoʻoponopono i kēia nui e like me ka mea e pono ai. ʻO ia hoʻi, inā haʻahaʻa ka pale ʻana, hiki i kēia mau lāʻau ke hoʻonui iā ia, a inā kiʻekiʻe loa ka pale ʻana, hiki iā lākou ke hoʻēmi a kāohi iā ia . He hana kikoʻī loa kēia.
Hana nui kēia mau lāʻau lapaʻau ma nā ʻano ʻelua:
E like me kā mākou i ʻōlelo ai ma mua, aia ʻelua mau ala nui e hana ai kēia mau lāʻau. ʻO ka hoʻomaopopo ʻana i kēia e kōkua iā ʻoe e hoʻomaopopo maikaʻi i kēia lāʻau.
| Hana | He aha ka hana a kēia? (He aha kāna hana) |
|---|---|
| Ke hoʻoikaika nei i ka pane ʻana o ka pale kino | I kekahi mau kūlana maʻi, ʻoiai ke kanesa, he maikaʻi loa nā hunaola kanesa i ka hūnā ʻana mai ko mākou ʻōnaehana pale. ʻO ka hana a kēia mau lāʻau lapaʻau, ʻo ia ka hāʻawi ʻana i ko mākou "pūʻali koa" i ka ikaika a me ke aʻo ʻana e pono ai e ʻimi a luku i kēia mau ʻenemi huna. |
| Ke kāohi nei i ka pane ʻana o ka maʻi pale | Ua kapa kikoʻī mākou i kēia mau lāʻau lapaʻau he Immunosuppressants.Pono kēia mau mea no ka poʻe me nā maʻi autoimmune. I loko o kēia mau maʻi, hoʻouka hewa ko kākou ʻōnaehana pale ponoʻī i ko kākou mau hunaola olakino ponoʻī. Eia kekahi, ke hana ʻia kahi hoʻoili kino, kōkua kēia mau lāʻau i ke kino ʻaʻole e hōʻole i ke kino hou. |
He aha nā kūlana nui e hoʻohana ʻia ai nā immunomodulators?
Hoʻohana ʻia kēia ʻano lāʻau lapaʻau e mālama i nā ʻano maʻi like ʻole. ʻO kekahi o lākou:
- Nā maʻi hono a me nā maʻi pili: ʻO kēia nā ʻano maʻi autoimmune nui. No ka laʻana, i nā maʻi e like me ka `(Rheumatoid Arthritis)` (ka mumū o ke hono), `(Lupus)`, `(Psoriatic Arthritis)`, `(Ankylosing Spondylitis)`, kōkua kēia mau lāʻau i ka hoʻouka ʻana o ke kino i kona mau hono ponoʻī, ʻili, a pēlā aku.
- Nā maʻi o ka ʻōnaehana hoʻoheheʻe: I nā maʻi e like me ka "Maʻi Crohn" a me ka "Ulcerative Colitis", hoʻohana ʻia kēia mau mea e kāohi i ke kaʻina hana pale kino makemake ʻole e kū mai ana i loko o nā ʻōpū.
- Nā maʻi ʻili: I nā maʻi e like me ka psoriasis, kaohi ka ʻōnaehana pale i ka ulu wikiwiki ʻana o nā ʻili.
- Nā maʻi o ka ʻōnaehana nerve: Kōkua kēia mau lāʻau lapaʻau i ka kaohi ʻana i ka hōʻino ʻia o ka ʻōnaehana nerve i nā maʻi e like me ka "Multiple Sclerosis".
- Ka maʻi ʻaʻai: I kekahi mau ʻano maʻi ʻaʻai, hoʻohana ʻia kēia mau mea e hoʻoulu i ka ʻōnaehana pale e luku i nā hunaola maʻi ʻaʻai. He ʻāpana kēia o kahi lāʻau i kapa ʻia ʻo "Immunotherapy."
He aha nā ʻano nui o nā immunomodulators?
ʻAʻole like ke ʻano o kēia mau lāʻau āpau. Kuhikuhi nā kauka i nā ʻano "Immunomodulators" like ʻole ma muli o ke ʻano o ka maʻi.
Nā Corticosteroids
ʻO kēia nā lāʻau lapaʻau immunosuppressant i hoʻohana nui ʻia e ka poʻe he nui. ʻO kahi laʻana ʻo `(Prednisone).` Hana kēia mau mea ma ka hōʻemi koke ʻana i ka hana o ka ʻōnaehana pale a me ka kaohi ʻana i ka pehu a me ka mumū i loko o ke kino.
Nā DMARD (Nā Lāʻau Lapaʻau Antirheumatic Hoʻololi i ka Maʻi)
E like me ka inoa e hōʻike nei, he mau lāʻau lapaʻau kēia e kōkua i ka hoʻololi ʻana i ke ʻano o kahi maʻi. ʻOi loa aku i nā maʻi e like me ka arthritis, kōkua kēia mau lāʻau lapaʻau i ka pale ʻana a i ʻole ka hoʻomalu ʻana i ka hōʻino ʻia o nā hono i hoʻokumu ʻia e ka maʻi, ma mua o ka hōʻemi wale ʻana i ka ʻeha. He lāʻau lapaʻau kaulana loa ʻo `(Methotrexate)` ma kēia papa.
Nā mea olaola
He papa lāʻau hou kēia a ʻoi aku ka holomua ma mua o nā DMARD. Hana ʻia lākou mai nā protein i unuhi ʻia mai nā pūnaewele ola ma kahi keʻena hoʻokolohua.
I ka ʻōlelo maʻalahi, ʻoiai nā lāʻau lapaʻau kahiko e hana e like me nā 'carpet bombs' a hoʻopilikia i ka ʻōnaehana pale holoʻokoʻa, ua like nā biologics me nā 'smart bombs'. ʻO ia hoʻi, hele pololei lākou a kuhikuhi wale i kahi cell a i ʻole kemika kikoʻī (e like me `(TNF)`, `(Interleukin)`) e hoʻoulu nei i ka maʻi.
Hiki paha i kēia ke hōʻemi i nā hopena ʻaoʻao a alakaʻi i nā hopena maikaʻi aʻe.
ʻO ka Immunotherapy no ke Kanesa
He ʻano lapaʻau kūikawā loa kēia. ʻO ka mea e hana ʻia ma ʻaneʻi, ʻaʻole ia he emi ʻana o ka ʻōnaehana pale, akā, ua hoʻonui ʻia. Hoʻōki nā lāʻau lapaʻau e like me "Checkpoint Inhibitors" i nā "hōʻailona" a nā hunaola maʻi kanesa e hoʻohana ai e hūnā mai kā mākou mau hunaola pale ("(T-cells)"), a kōkua i nā T-cell e ʻike a luku i nā hunaola maʻi kanesa.
Pehea e hāʻawi ʻia ai kēia lāʻau i ke kino?
ʻOkoʻa paha ke ʻano o ka hāʻawi ʻana i kēia lāʻau lapaʻau iā ʻoe ma muli o kou kūlana olakino a me ke ʻano o ka lāʻau lapaʻau.
- Ma o kahi aa koko (Ma o IV): E like me ka saline, hāʻawi pololei ʻia i loko o ke kahe koko ma o kahi cannula.
- Ma ka Inikini: Hoʻokomo ʻia ma lalo o ka ʻili a i ʻole i loko o kahi ʻiʻo.
- Waha: Lawe ʻia ma ka waha e like me nā papa a i ʻole nā capsules.
- Ma ke ʻano he kirīmi ma ka ʻili (Ma ke ʻano kūloko): Hoʻopili ʻia ia ma ka ʻili o ka ʻili ma ke ʻano he kirīmi no nā maʻi ʻili.
E makaʻala hoʻi kākou i nā hopena ʻaoʻao a me nā pilikia.
ʻOiai he mau lāʻau lapaʻau pono loa kēia, hiki iā lākou ke loaʻa kekahi mau hopena ʻaoʻao a me nā pilikia no ka mea e hoʻopilikia lākou i ka ʻōnaehana pale. Na kāu kauka e aʻo iā ʻoe e pili ana i kēia mau mea.
| ʻAno pilikia | Nā mea e makaʻala ai |
|---|---|
| Nā hopena ʻaoʻao maʻamau | Hiki paha iā ʻoe ke loaʻa ka luhi, ka hiamoe, ka nausea, ka ʻeha o ka ʻōpū, a me nā ʻulaʻula o ka ʻili. Maʻamau, e emi iho kēia mau mea i ka hala ʻana o ka manawa. |
| Nā pilikia kūikawā (i ka wā e hoʻopau ʻia ai ka pale ʻana o ka maʻi) | Ua hoʻonāwaliwali ʻia nā "mana pale" o kou kino, no laila ʻoi aku ka nui o ka loaʻa ʻana o nā maʻi.Hiki i ke anu a i ʻole ka maʻi palū ke lilo i mea koʻikoʻi. No laila, pono ʻoe e mālama i nā mea e like me ka pale ʻana i nā wahi lehulehu a me ka holoi pinepine ʻana i kou mau lima. Inā loaʻa iā ʻoe nā hōʻailona e like me ke kuni, ka ʻū, a i ʻole ka paʻakikī o ka hanu ʻana, e ʻike koke i ke kauka. |
| Nā pilikia kūikawā (i ka wā e hoʻoikaika ai i ka palekana) | I kekahi manawa hiki i ka ʻōnaehana pale ke hoʻoulu nui ʻia a hoʻomaka e hoʻouka i nā ʻiʻo olakino. Hiki i kēia ke hana i nā mea e like me nā pilikia hormonal, nā pilikia ʻili, a me ka maʻi pākī. |
ʻOiai ke ʻano o ka hihia, ua ʻike pono kāu kauka i kēia mau pilikia. ʻO ia ke kumu e nānā mau ai ʻo ia iā ʻoe, hana i nā hoʻokolohua koko e pono ai, a hoʻoponopono i ka nui o kāu lāʻau lapaʻau e mālama pono iā ʻoe. ʻO kāu wale nō e hana ai, ʻo ia ke haʻi aku i kāu kauka e pili ana i nā loli a i ʻole ka ʻoluʻolu ʻole āu e manaʻo ai.
Leka Lawe-Home
- He papa ikaika loa nā lāʻau lapaʻau Immunomodulators a he ʻano kūikawā hoʻi ia e hoʻololi ai i ka hana o kāu ʻōnaehana pale e like me ka mea e pono ai.
- Hiki ke hoʻohana ʻia kēia mau mea e hoʻoikaika i ka pale ʻana (i nā maʻi e like me ke kanesa) a hōʻemi paha iā ia (i nā maʻi autoimmune).
- ʻAʻole like kēia me nā lāʻau ʻeha maʻamau. He mau lāʻau kēia e hoʻopilikia ai i ke kumu o kahi maʻi.
- E mālama pono iā ʻoe iho mai nā maʻi i ka wā e lawe ai i kēia mau lāʻau.
- Mai kānalua e hoʻomaopopo i kāu kauka e pili ana i nā hopena ʻaoʻao a i ʻole nā hōʻailona hou āu e ʻike ai.
- Mahalo i kēia mau lāʻau lapaʻau, ua hoʻomalu pono ʻia nā maʻi he nui i manaʻo ʻia he paʻakikī ke mālama ʻia. No laila, he mea nui loa ka hahai pololei ʻana i nā ʻōlelo aʻoaʻo lapaʻau.
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