Ke paʻakikī nei hoʻi iā ʻoe ke hanu ma muli o ka hānō a i ʻole nā ​​​​​​maʻi ʻaleka? A laila e aʻo kākou e pili ana i kēia mau Leukotriene Modifiers!

I kekahi manawa, ʻoiai kahi lepo liʻiliʻi, ka pollen, a i ʻole ka meaʻai e hiki ai iā ʻoe ke manaʻo i ka hanu pōkole, ka paʻa o ka umauma, a i ʻole ka ʻū mau. Malia paha he ihu wai kou, ka ʻūhā, a i ʻole ka ʻāʻī ʻūlū. He mea hoʻonāukiuki maoli kēia, ʻeā? ʻO ka hapa nui o ka manawa, ua hoʻokumu ʻia kēia mau hōʻailona e kahi hopena i loko o ko mākou kino. I kēia lā, e kamaʻilio mākou e pili ana i kahi ʻano lāʻau lapaʻau kūikawā e hiki ke kōkua i ka hoʻomalu ʻana i nā pilikia hanu i hoʻokumu ʻia e nā kūlana e like me ka hānō a me nā maʻi allergies. Ua kapa ʻia lākou ʻo Leukotriene Modifiers .

He aha nā leukotrienes? No ke aha lākou e hoʻopilikia mai ai iā mākou?

I ka ʻōlelo maʻalahi, he mau kemika nā leukotrienes a ko mākou kino e hana ai. ʻAʻole lākou i hana wale ʻia ma ka manawa kūpono. E noʻonoʻo, i ka wā e maʻi ai ʻoe i kahi mea, ʻo ia hoʻi, i ka wā e komo ai kekahi mea i kou kino, no ka laʻana, ka lepo, ka pollen, kekahi mau meaʻai, a laila hoʻāla koke kā mākou ʻōnaehana pale a hoʻokuʻu i kēia mau leukotrienes.

Aia i ka wā e hoʻokuʻu ʻia ai kēia mau leukotrienes e hoʻomaka ai mākou e loaʻa nā pilikia. ʻO ka ʻōnaehana hanu ma ke ʻano kūikawā ka mea i hoʻopilikia nui ʻia. E nānā kākou i ka mea e hana ʻia:

• Kuke: Hiki ke loaʻa ka kuke mau, a i kekahi manawa ʻeha.
• Hoʻonui ʻia ka mucus: Hoʻomaka nā wai e like me ka mucus a me ka phlegm e hōʻiliʻili i loko o ka umauma a me ka puʻu. Hiki i kēia ke hana i kahi leo hū i ka wā e hanu ana.
• Ka pehu ʻana o nā ala ea: Hoʻomaka ko kākou mau ala ea, nā wahi a kākou e hanu ai, e pehu mai loko mai. E like me ka pehu ʻana o kahi paipu wai mai loko mai, e liʻiliʻi ana ka hakahaka no ke kahe ʻana o ka wai.
• ʻO ke kuʻi ʻana o nā ʻiʻo o ke ala ea: Hoʻopaʻa a ʻūlū nā ʻiʻo liʻiliʻi a puni nā ala ea, e hoʻohāiki ana i nā ala ea.
• Paʻa ka umauma: Malia paha e like me ke ʻomi ʻia nei kou umauma e kekahi, me he mea lā e ʻomi ʻia ana.
• Paʻakikī ka hanu ʻana a i ʻole ka wheezing: Ke hui pū ʻia nā mea a pau i luna, lilo ka hanu ʻana i mea paʻakikī loa. Hiki i kekahi poʻe ke ʻike i ka wheezing.

ʻIke ʻoe, ʻo kēia mau kemika liʻiliʻi i kapa ʻia ʻo leukotrienes ke hoʻopilikia nui nei iā mākou.

No laila he aha kēia mau mea hoʻololi leukotriene? He aha ka mea e kōkua ai kēia mau lāʻau lapaʻau?

ʻAe, i kēia manawa ua ʻike mākou he kuleana pinepine nā leukotrienes no kēia mau pilikia hanu. ʻO nā mea hoʻololi leukotriene kahi ʻano lāʻau lapaʻau e kāohi a hoʻololi i ka hana o kēlā mau leukotrienes. Ua kapa ʻia lākou he mau antagonists receptor leukotriene a i ʻole nā ​​​​mea hoʻopaʻa synthesis leukotriene.ʻAe. ʻOiai he paʻakikī iki ka inoa, hana kēia mau lāʻau lapaʻau i kahi mea nui loa.

Hoʻohana nui ʻia kēia mau lāʻau lapaʻau no:

• Nā maʻi ʻaleka, ʻoi aku hoʻi ka Allergic Rhinitis: ʻO kēia ka mea a mākou e kapa pinepine ai he maʻi ʻaleka i nā ʻuku lepo a i ʻole nā ​​​​pōpoki. ʻO nā hōʻailona e komo pū me ka ihu wai, ka ʻūhā, ka ihu paʻa, a me nā maka ʻāʻī.
• Asthma Allergy: Inā hoʻonui ʻia nā hōʻailona hānō e kahi maʻi allergy, hiki i kēia lāʻau lapaʻau ke kōkua.
• Hānau i hoʻoulu ʻia e ka hoʻoikaika kino: Hiki i kekahi poʻe ke ʻike i ka piʻi ʻana o ko lākou mau hōʻailona hānau i ka wā e hoʻoikaika kino ai, holo, a lele paha. He mea pono nō hoʻi kēia lāʻau lapaʻau i ia mau hihia.

ʻO ka mea nui, ʻaʻole hoʻohana ʻia kēia mau lāʻau lapaʻau e hōʻemi koke i kahi hopena alerika a i ʻole kahi hōʻeha hānō i loaʻa mua. Hoʻohana ʻia lākou e pale aku i kēlā mau kūlana mai ka hanana ʻana a i ʻole e hōʻemi i kā lākou mau hōʻailona . Ua like ia me ka umbrella, inā ʻoe e paʻa i luna ma mua o ka ua, ʻaʻole ʻoe e pulu. Pēlā ia.

He aha nā ʻano o nā mea hoʻololi Leukotriene i loaʻa?

Aia kekahi mau ʻano lāʻau lapaʻau ma kēia māhele. Ke kuhikuhi kāu kauka i hoʻokahi nou, hiki ke kapa ʻia ʻo ia kekahi o kēia mau inoa:

• Montelukast - Ua lohe paha ʻoe i kēia ma lalo o ka inoa inoa ʻo `Singulair®`.
• Zafirlukast - Aia kēia ma lalo o ka inoa inoa ʻo 'Accolate®'.
• Zileuton - Loaʻa kēia ma lalo o ka inoa inoa ʻo `Zyflo®`.

Hoʻohana ʻia nā mea ʻekolu a pau no ka mālama ʻana i ka hānō. Eia nō naʻe, ʻo Montelukast wale nō i ʻae ʻia e mālama i ka rhinitis allergic , ʻo ia hoʻi, nā maʻi ʻaleka ihu.

Pehea e hana ai kēia mau lāʻau lapaʻau? He mea kupaianaha ia, ʻeā?

Hana kēia mau lāʻau lapaʻau ma nā ʻano ʻelua. Me he mea lā he ʻelua mau hopena i kahi pilikia.

1. No Montelukast lāua ʻo Zafirlukast i kahi hui o nā lāʻau i kapa ʻia ʻo leukotriene receptor antagonists . E noʻonoʻo he mau 'loka' liʻiliʻi i loko o kou kino, a i ka wā e hele mai ai kēia mau kemika i kapa ʻia ʻo leukotrienes a komo i loko o kēia laka e like me ke 'kī', loaʻa kēlā pilikia hanu. ʻO ka mea a kēia lāʻau e hana ai, ma mua o ke komo ʻana o kēia kī leukotriene i loko o kēlā laka, e ālai ia i kēlā laka ma ka hoʻokomo ʻana i kahi kī 'dummy' ʻē aʻe. A laila ʻaʻole hiki i kēlā mau leukotrienes ke hana. ʻO ia hoʻi, hoʻōki ia i ka hopena o nā leukotrienes.

2. He ʻokoʻa iki ʻo Zileuton . No kahi hui o nā lāʻau lapaʻau i kapa ʻia he mau mea hoʻopale synthesis leukotriene.ʻO kēia ka mea e hana ai ma ka hana ʻana i kēlā mau kemika 'pilikia' i kapa ʻia ʻo leukotrienes i loko o ke kino, ʻo ia hoʻi, e hōʻemi ana i kā lākou hana ʻana. Ua like ia me ke kāohi ʻana i ka hana ʻana o nā waiwai ma kahi hale hana. A laila e emi ana ka nui o nā leukotrienes i loko o ke kino.

Maopopo iā ʻoe? Ma kekahi ʻano, ʻaʻole ia e ʻae i nā leukotrienes e hana, a ma kekahi ʻano, hoʻemi ia i ka hana ʻana o nā leukotrienes.

Pehea e hoʻohana ai i kēia lāʻau lapaʻau? He aha kaʻu e makaʻala ai?

ʻO ka maʻamau, hele mai kēia mau mea hoʻololi leukotriene ma ke ʻano o nā papa, ʻo ia hoʻi ke lawe ʻia nei ma ka waha .

ʻO ka mea nui loa, ʻo ia ka lawe ʻana i kēia lāʻau lapaʻau i kēlā me kēia lā e like me ke kauoha a kāu kauka . He mea nui e lawe i ka lāʻau lapaʻau i ka manawa kūpono, inā paha he paʻakikī kou hanu ʻana i kēlā lā a i ʻole. No ka mea, e like me kā mākou i ʻōlelo ai ma mua, hoʻohana ʻia kēia mau mea e pale aku i nā pilikia hanu. E like me ka huaora o kēlā me kēia lā, pono ʻoe e lawe i kēlā me kēia lā e mālama i ka pale āna e hāʻawi ai.

E hāʻawi aku kāu kauka iā ʻoe i kekahi mau ʻōlelo kikoʻī e pili ana i kēia lāʻau lapaʻau:

• Ka nui o ka lawe ʻana: ʻO ia hoʻi ka nui e lawe ai a me nā manawa o ka lā.
• I ka manawa e lawe ai i ka lāʻau lapaʻau: I ke kakahiaka, ʻelua i ka lā, a i ʻole i ka pō. Pili paha kēia i ka wā e ʻoi loa ai kou mau hōʻailona.
• Inā paha e lawe me ka meaʻai a i ʻole me ka ʻole o ka meaʻai: Pono e lawe ʻia kekahi mau lāʻau lapaʻau ma mua o ka ʻai ʻana, a ʻo kekahi ma hope o ka ʻai ʻana. E nīnau pono iā ia.

Mai lawe i ka nui a i ʻole ka emi ʻana o kēia lāʻau lapaʻau ma mua o ka mea i kauoha ʻia e kāu kauka. ʻO ka hana ʻana pēlā e hōʻemi paha i ka pono o ka lāʻau lapaʻau a hoʻoulu i nā hopena ʻaoʻao i makemake ʻole ʻia.

He aha nā pōmaikaʻi o ka hoʻohana ʻana i nā Leukotriene Modifiers?

Inā hoʻohana pono ʻoe i kēia mau lāʻau lapaʻau, hiki iā ʻoe ke loaʻa ka nui o ka hōʻoluʻolu. Eia nā pono:

• E maʻalahi ka hanu ʻana: Ua emi iho ka paʻa o ka umauma a me ka hanu ʻana, a hiki iā ʻoe ke hanu hou aku.
• Hiki iā ʻoe ke hoʻoikaika kino me ka paʻakikī o ka hanu ʻana: Inā ua ʻike mua ʻoe i ka pōkole o ka hanu i ka wā e hoʻoikaika kino ana, e ʻae kēia lāʻau lapaʻau iā ʻoe e kāohi i ke kūlana a komo i ka hoʻoikaika kino.
• Kōkua i ka wehe ʻana o nā ala ea: Ua ʻōlelo mākou e pehu nā ala ea a paʻa, no laila e hōʻemi ana i kēlā mau kūlana.
• Hoʻēmi i ka mucus ma ka umauma a me ka ʻāʻī: Ua hoʻemi ʻia ka mucus, e maʻalahi ai ka hanu ʻana.
• Kōkua i ka pale ʻana i nā pilikia hanu, e like me nā hopena alerika a me nā hōʻeha hānō.
• Hoʻemi i ka helu a me ke koʻikoʻi o nā hopena a me nā hoʻouka kaua.

Hiki i kēia ke maʻalahi i kou ola o kēlā me kēia lā.

Aia kekahi mau pilikia me kēia mau lāʻau lapaʻau?

E like me nā lāʻau lapaʻau a pau, hiki i kēia mau mea hoʻololi leukotriene ke loaʻa kekahi mau pilikia.

Ka hōʻino ʻana o ke akepaʻa i hana ʻia e kekahi mau mea hoʻololi leukotrieneHiki nō. No laila, inā loaʻa iā ʻoe kahi maʻi akepaʻa, ʻaʻole paha ʻoe e hiki ke hoʻohana i kēia mau lāʻau lapaʻau. ʻOiai ʻoe e lawe ana i kēia lāʻau lapaʻau, hiki i kāu kauka ke hana i nā hoʻokolohua koko e nānā inā e hana pono ana kou akepaʻa. No kou palekana kēia.

He aha nā hopena ʻaoʻao e hiki mai ana?

Ua manaʻo ʻia he palekana nā mea hoʻololi Leukotriene. Eia nō naʻe, hiki i kekahi poʻe ke loaʻa nā hopena ʻaoʻao. Mai hopohopo, ʻaʻole koʻikoʻi kēia mau mea.

Nā hopena ʻaoʻao i ʻike pinepine ʻia:

• Nā hōʻailona o ke anu: ʻū, ʻeha ka puʻu, kahe ka ihu.
• ʻŌpū ʻeha: Ka maʻi kahe, ʻeha ʻōpū.
• Ka maʻi pepeiao.
• Luhi: ʻO ia hoʻi ka manaʻo luhi.
• Nā hōʻailona e like me ka maʻi palū: kuni.
• ʻEha poʻo .
• ʻĀhaʻi: Ua like ia me kahi mea e ʻā ana i loko o ka umauma.
• ʻŌhūhū a ʻulaʻula paha.
• ʻAʻohe ʻono o ka meaʻai.
• Nausea: Manaʻo e like me ka luaʻi ʻana.

Inā loaʻa iā ʻoe kahi hopena maʻamau e like me kēia, inā ʻaʻole ia e nalowale i loko o kekahi mau lā, a inā paha he paʻakikī iā ʻoe ke ʻae, e kamaʻilio me kāu kauka.

Eia nō naʻe, i kekahi manawa hiki ke loaʻa nā hopena ʻaoʻao koʻikoʻi. Inā ʻike ʻoe i kekahi mea e like me kēia, pono ʻoe e ʻike i ke kauka a i ʻole e hele koke i ka haukapila:

• Nā loli i ke olakino noʻonoʻo: He mea nui loa kēia. Inā ʻike ʻoe i ke kaumaha , nā manaʻo o ka pepehi kanaka iā ʻoe iho , a i ʻole ka huhū koke , mai hoʻowahāwahā iā ia. Ua hōʻike kekahi poʻe e lawe ana i kēia lāʻau lapaʻau ua loaʻa iā lākou kēia mau hopena noʻonoʻo. No laila, inā ʻike ʻoe a i ʻole kekahi o kou ʻohana i kahi loli nui i ke ʻano a i ʻole ke ʻano o ka naʻau i ka wā e lawe ana i kēia lāʻau lapaʻau, e haʻi koke i ke kauka.
• ʻO ka pehu, ka ʻili ʻana, a i ʻole nā ​​​​​​mea ʻulaʻula nui e like me ka hives.
• Ka leo haʻalulu a i ʻole ka ʻāʻī ʻeha.
• Nā palpitations o ka puʻuwai.
• Ka maneʻo a i ʻole ke ʻano ʻūlū ma nā lālā.
• Ka pehu ʻana o ka maka, nā maka, ka waha, a i ʻole ka puʻu.
• Ka paʻakikī i ka hanu ʻana a i ʻole ke ale ʻana.
• Ka luaʻi ʻana.
• Melemele o ka ʻili a i ʻole nā ​​​​maka (Jaundice): He pilikia paha kēia i ke akepaʻa.

Inā ʻike ʻoe i kahi mea koʻikoʻi e like me kēia, ʻoi aku ka maikaʻi o ka ʻimi ʻana i ke kōkua lapaʻau me ka hoʻonele ʻole i ka manawa.

Aia kekahi mau pilina me nā lāʻau lapaʻau ʻē aʻe?

ʻAe, hiki i nā Leukotriene Modifiers ke launa pū me nā lāʻau lapaʻau ʻē aʻe āu e lawe nei. No laila, he mea nui loa e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei, me nā lāʻau lapaʻau i kauoha ʻia, nā lāʻau hoʻopau ʻeha ma luna o ke kauka, nā huaora, a me nā lāʻau lapaʻau lāʻau.

ʻO kekahi mau lāʻau lapaʻau e hiki ke launa pū me kēia mau lāʻau lapaʻau:

• Kekahi mau lāʻau lapaʻau no ka maʻi ʻaʻai (e.g. `Alpelisib`, `dabrafenib`, `enzalutamide`).
• Kekahi ʻano antibiotics (e.g. 'Erythromycin', 'rifapentine').
• Kekahi mau lāʻau lapaʻau no ka maʻi noʻonoʻo (e like me Loxapine - he lāʻau lapaʻau no nā maʻi like me schizophrenia ).
• Nā lāʻau lapaʻau no ka cystic fibrosis (e.g. Lumacaftor).
• Kekahi mau antihistamines (e.g. Terfenadine - kahi lāʻau lapaʻau i hoʻohana ʻia e pale a mālama paha i nā hōʻailona allergies).
• Nā lāʻau hoʻokahe koko (e like me 'Warfarin' - kahi lāʻau lapaʻau e kōkua ai i ka pale ʻana i nā ʻaʻa koko, nā hahau, a me nā hōʻeha puʻuwai).

ʻAʻole i piha kēia papa inoa. No laila, e kamaʻilio pono me kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe ai i hiki iā ia ke kuhikuhi i ka lāʻau lapaʻau palekana a kūpono hoʻi nāu.

Leka Lawe-Home

ʻAe, no laila ke lana nei koʻu manaʻo ua ʻike maikaʻi ʻoe i nā Leukotriene Modifiers a mākou i kamaʻilio ai i kēia lā.

I ka pōkole, kōkua kēia mau lāʻau lapaʻau i ka pale ʻana i nā pilikia hanu i hoʻokumu ʻia e kou mau maʻi allergies a i ʻole ka hānō. Pono lākou e lawe ʻia i kēlā me kēia lā, inā he mau hōʻailona kou a ʻaʻole paha, a e like me ke kuhikuhi a kāu kauka. ʻO kāu kauka ke kanaka maikaʻi loa e ʻike inā kūpono kēia lāʻau lapaʻau iā ʻoe a inā e pōmaikaʻi ia iā ʻoe.

No laila, inā loaʻa iā ʻoe kēia ʻano pilikia hanu, mai makaʻu e kamaʻilio me ke kauka a nīnau e pili ana i kēia ʻano lāʻau lapaʻau. Pono nā kānaka a pau e hanu me ke kūʻokoʻa a ola i ke ola olakino!

ʻO nā leukotrienes, nā mea hoʻololi leukotriene, ka hānō, nā maʻi ʻaleka, nā pilikia hanu, montelukast, zafirlukast, zileuton, nā maʻi hanu