E loli loa anei ke ʻano o ka ʻike ʻia ʻana o ka maʻi Alzheimer?

Makaʻu iki mākou a pau ke ʻike mākou i ko mākou mau mākua a me nā kūpuna e nalowale mālie ana ko lākou hoʻomanaʻo i ko lākou wā ʻelemakule. "ʻO kēia anei ka hoʻomaka ʻana o ka maʻi Alzheimer?" Aia ka nīnau ma hope o ko mākou manaʻo. A hiki i kēia manawa, ua ʻike pinepine ʻia ka maʻi Alzheimer ma ka nānā ʻana i ka hoʻomanaʻo o ke kanaka a me ka ʻimi ʻana i nā hōʻailona e like me nā loli o ke ʻano. Akā i kēia manawa, ua hāpai mai kahi hui o nā loea lapaʻau kaulana o ka honua i kahi manaʻo nui e hoʻololi i kēia ʻōnaehana. Ke ʻōlelo nei lākou ma kahi o ke kali ʻana i nā hōʻailona e ʻike ʻia, pono mākou e hoʻohana i nā hōʻike olaola i loko o ke kino e ʻike i kēia maʻi ma mua o ka hiki ʻana mai.

No ke aha e pono ai ia ʻōnaehana hou?

Ke noʻonoʻo nei paha ʻoe, "No ke aha e hoʻololi ai i kēia ʻōnaehana? Aia kekahi hewa me ka ʻōnaehana o kēia manawa?" ʻOiaʻiʻo, ʻike wale ka ʻōnaehana o kēia manawa i ka maʻi ma hope o ka loaʻa ʻana o kekahi pōʻino i ka lolo a ua hoʻomaka kona hopena e hōʻike ʻia ma ke ʻano he mau hōʻailona. ʻO ia hoʻi, ua lohi iki ka loaʻa ʻana o kahi hōʻailona.

Akā ʻo kēia ka manaʻo nui o kēia noi hou.

I ka ʻōlelo maʻalahi, e like me ka mākaʻi e ʻimi nei i nā hōʻailona ma mua o ka hana ʻia ʻana o kahi hewa, ʻo ka pahuhopu ka ʻike ʻana i nā loli i ke kino ma mua o ka puka ʻana o nā hōʻailona a me ka ʻike ʻana i ka maʻi. ʻO ke kumu o kēia, me nā holomua hou o ka ʻepekema lapaʻau, ua hoʻomohala ʻia nā ʻano hoʻāʻo hou e hiki ke ʻike i kēlā mau hōʻailona olaola. ʻAe kēia i nā mea maʻi e ʻike e pili ana i ko lākou kūlana ma mua, e hoʻoholo e pili ana i ko lākou ola e like me ia, a e ʻimi koke i ka lāʻau lapaʻau e pono ai. Eia kekahi, i kekahi manawa aia paha nā maʻi ʻē aʻe e hōʻike ana i nā hōʻailona like me ka maʻi Alzheimer. Mahalo i kēia ʻano hana hou, ʻoi aku ka maʻalahi o nā kauka e ʻike pololei a wikiwiki inā he Alzheimer maoli a i ʻole kekahi maʻi ʻē aʻe.

He aha kēia mau biomarkers?

Ke lohe ʻoe i ka huaʻōlelo " bimarkers ," manaʻo paha ʻoe he huaʻōlelo nui a paʻakikī. Akā, he mea maʻalahi loa ia. E noʻonoʻo i ko kākou kino e like me nā kaʻa. Ke hoʻomaka kekahi mea e hewa me ka ʻenekini o ke kaʻa, i kekahi manawa e ʻā ana ke kukui hōʻike ma ka dashboard, ʻeā? Pēlā nō, ke hoʻomaka kekahi mea e hewa i loko o ko kākou kino, ʻike kākou i nā hōʻailona o ia mea i loko o ko kākou koko, ka wai cerebrospinal, a i ʻole nā ​​ʻiʻo ʻē aʻe. ʻO ia ka mea a kākou e kapa nei he biomarkers.

I ka wā e pili ana i ka maʻi o Alzheimer, ʻelua mau biomarkers nui.

1. Nā protein Beta-amyloid: Hōʻiliʻili kēia mau mea i loko o ka lolo a hana i nā puʻupuʻu liʻiliʻi (nā plaques).

2. Nā protein Tau: Hōʻiliʻili kēia i loko o nā hunaola nerve i loko o ka lolo a hana i nā hiʻohiʻona.

A hiki i kēia manawa, ʻo ke ala wale nō e ʻike pololei ai i ke alo o kēia mau protein ma o nā scan lolo kūikawā (a pipiʻi hoʻi). Akā i kēia manawa, ua hoʻomohala ʻia nā hoʻokolohua koko hou e hiki ke ana maʻalahi i nā pae o kēia mau protein. ʻO kēia ka holomua nui loa i kēia manaʻo.

ʻO kahi ʻōnaehana hoʻonohonoho e like me ke kanesa

Ua lohe paha ʻoe i ke kanesa. Ma hope o ka ʻike ʻia ʻana o kahi kanesa, hoʻokaʻawale nā ​​kauka iā ia i nā pae e like me "Stage 1" a me "Stage 2." Hāʻawi kēia i ka mea maʻi a me ka poʻe e mālama nei iā lākou i kahi ʻike maopopo i ke koʻikoʻi o ka maʻi a me ka mamao o kona laha ʻana.

I kēia manawa, ke manaʻo nei kēia poʻe loea e hoʻolauna i kahi ʻōnaehana hoʻonohonoho like no ka maʻi Alzheimer. Wahi a kēia ʻōnaehana, ua hoʻokaʻawale ʻia kahi mea maʻi i nā pae 0 a 6. Hoʻokumu ʻia kēia hoʻokaʻawale ʻana ma ke alo o nā biomarkers i ʻōlelo ʻia ma luna, a me nā loli noʻonoʻo maalea i ka hoʻomanaʻo a me ke ʻano. E ʻae kēia i ka mea maʻi a me ka ʻohana e hoʻomaopopo pono i ke pae o ka maʻi.

Pehea ka hana ʻana o kēia ʻōnaehana pae hou?

Ke kūkākūkā ʻia nei kēia ʻōnaehana i manaʻo ʻia, akā e like me ke kūlana i kēia manawa, penei ka hoʻokaʻawale ʻana o nā pae.

Aia nā pono a me nā pilikia i kēia ʻano hana.

ʻO ka pōmaikaʻi nui o kēia ʻano hana hou, ʻo ia ka hiki ke ʻike i ka maʻi i ka wā mua loa . No laila, hiki i ka poʻe i kēia pae mua ke pōmaikaʻi nui mai nā lāʻau lapaʻau hou.

Akā, aia kahi pilikia nui a me ka nui o nā hoʻopaʻapaʻa. E noʻonoʻo inā ʻoe e haʻi aku i kahi kanaka olakino, me ka ʻole o ka poina a i ʻole nā ​​hōʻailona, ​​​​ma ka nānā wale ʻana i ka hopena o ka hoʻāʻo koko a me ka ʻōlelo ʻana, "He maʻi Alzheimer kou i ka wā mua," he aha ka mea e hana ʻia? Pehea lā e pili ai kēlā i ke olakino noʻonoʻo o kēlā kanaka, kā lākou mau kulekele ʻinikua, a me kā lākou hana? He mea kēia a kekahi mau loea lapaʻau e nīnau nei. No laila, inā hāʻawi ʻia kēlā ʻano hōʻailona, ​​​​he mea nui loa ia e hāʻawi i ka mea maʻi i ka ʻōlelo aʻo kūpono i ka manawa like. Ke hoʻopaʻapaʻa mau nei kēia i waena o nā loea.

Eia nō naʻe, ke hōʻike nei kēia manaʻo e kokoke ana mākou e lele nui i mua i ka ʻike ʻana a me ka mālama ʻana i ka maʻi o Alzheimer.