Loaʻa iā ʻoe kēia mau puʻupuʻu kakaikahi i loko o kou lolo? E aʻo kākou e pili ana iā Gangliocytoma a me Pineocytoma!

ʻĀ, i kekahi manawa lohe mākou i nā mea e like me, 'ʻōpū lolo', 'He ʻeha poʻo koʻu a e nānā wau'. Hoʻoluliluli maoli ia i koʻu puʻuwai ke lohe au i kekahi mea e like me ia. Akā ua ʻike anei ʻoe, ʻaʻole like nā ʻōpū āpau e hana ʻia i loko o ka lolo me ke ʻano maʻi ʻino. Aia kekahi mau ʻōpū e ulu mālie ana, he benign, ʻo ia hoʻi, ʻaʻole maʻi kanesa. I kēia lā e kamaʻilio mākou e pili ana i ʻelua mau ʻano ʻōpū lolo, he mea kakaikahi iki, akā he mea pono ke ʻike. ʻO kēia nā gangliocytoma a me pineocytoma.

He aha nā Gangliocytoma a me Pineocytoma?

I ka ʻōlelo maʻalahi, he mau ʻano puʻupuʻu lolo kakaikahi loa kēia, ʻaʻole weliweli (ʻo ia hoʻi, ʻaʻole maʻi kanesa - 'benign').

ʻO Gangliocytoma kahi ʻano puʻupuʻu e hoʻopilikia i nā ʻāpana o kāu ʻōnaehana nerve waena (ʻike ʻia hoʻi ʻo CNS).

ʻO kekahi ʻano, he pineocytoma, e ulu ana i loko o ka pineal gland, kahi gland liʻiliʻi i loko o kou lolo. ʻO ka pineal gland ka gland e kōkua i ka hoʻomalu ʻana i kā mākou hiamoe. E noʻonoʻo, he mea nui loa kēia gland liʻiliʻi no nā mea e like me ka hiamoe ʻana i ka pō a me ke ala ʻana i ke kakahiaka.

Ulu mālie nā ʻano puʻupuʻu ʻelua. ʻO ia ke kumu e lōʻihi ai kekahi manawa no ka ʻike ʻia ʻana o nā hōʻailona. Hoʻōla pinepine nā kauka iā lākou me ke ʻoki kino a i kekahi manawa me ka radiation therapy.

ʻO wai ka mea i ʻoi aku ka paʻakikī o ka loaʻa ʻana o kēia ʻano puʻupuʻu lolo?

ʻO ka ʻoiaʻiʻo, hiki ke ulu kahi ʻano puʻupuʻu i kapa ʻia ʻo gangliocytoma i nā kānaka o kēlā me kēia makahiki. ʻO ke ʻano kēia, hiki i kahi keiki liʻiliʻi a i ʻole kahi ʻelemakule ke pilikia. Eia nō naʻe, ʻike pinepine ʻia ia i nā poʻe ʻōpio ma waena o 10 a me 30 mau makahiki .

ʻO ka maʻamau, hoʻopilikia nā ʻōpū Pineocytoma i nā pākeke, ʻo ia hoʻi nā kānaka ma waena o 20 a me 64 mau makahiki. ʻO ka awelika o ka makahiki i ʻike ʻia ai ka maʻi ma kahi o 38 mau makahiki.

Ma nā ʻāpana hea o ko kākou ʻōnaehana nerve waena (CNS) e ulu ai nā ʻōpū gangliocytoma?

Hoʻomohala pinepine ʻia nā gangliocytomas ma nā ʻāpana o kou lolo i kapa ʻia ʻo nā temporal lobes . Aia kēia mau mea ma hope o kou mau pepeiao. Kōkua kēia mau temporal lobes i ka hoʻomalu ʻana i nā mea e like me kou hoʻomanaʻo, ka lohe ʻana, a me nā manaʻo. E noʻonoʻo, hoʻomanaʻo ʻoe i kahi hanana kahiko, hoʻolohe i kahi mele a hauʻoli iā ia, a hauʻoli a kaumaha paha ma muli o ka hana o kēia mau ʻāpana.

ʻAʻole wale kēlā, hiki i kēia puʻupuʻu ke ulu aʻe ma nā wahi aʻe o kou kino:

• ʻŌpū lolo: ʻO kēia ka ʻāpana e like me ke alahaka o kou lolo e hoʻopili ana i ka ʻaoʻao luna o kou lolo (cerebrum), ke kaula spinal, a me ka cerebellum. Hoʻouna ia i nā hōʻailona e kaohi i nā hana koʻikoʻi e like me kou hanu ʻana a me ka helu o ka puʻuwai.
• ʻO ka lolo:ʻO kēia ʻāpana o kou lolo, ma ke kua o kou poʻo, ke kāohi nei i kou kaulike, neʻe ʻana, a me ka ʻike. E noʻonoʻo e pili ana i ia mea, ʻo kēia ʻāpana o kou lolo ka mea e mālama pono iā ʻoe i kou hele ʻana, e pale aku iā ʻoe mai ka hāʻule ʻana, a kōkua iā ʻoe e hōʻea i luna e hopu i ka pōpō.
• Papahele o ke kolu o ka ventricle: He lua haiki kēia ma ke alo o ka lolo. Mālama ia i ka lolo mai ka ʻeha a kōkua i ka hoʻoneʻe ʻana i nā meaʻai a me nā huahana ʻōpala.
• ʻO ke kaula kuamoʻo: ʻO kēia ke ala nui e lawe ai i nā hōʻailona aʻalolo mai kou lolo a i kou kino a mai kou kino a i kou lolo. ʻO kēia mau hōʻailona aʻalolo ka mea e hoʻomaopopo ai i nā mea (wela, anu, ʻeha) a hoʻoneʻe i kou kino.

He aha ka ʻokoʻa ma waena o ka pineal cyst a me ka pineocytoma?

He mea kēia e hiki ai ke hoʻopilikia i nā poʻe he nui. E noʻonoʻo, he ʻeke piha ka pineal cyst i ka wai a i ʻole ka ea . Ua like ia me ka pehu wai. Loaʻa pinepine kēia mau mea i ka wā o ka scan. Eia nō naʻe, he puʻupuʻu ka pineocytoma i hoʻokumu ʻia e kahi hōʻiliʻili nui o nā cell ʻano ʻē .

ʻAʻole nui pinepine nā cysts pineal, ʻo ia hoʻi, ʻaʻole pinepine lākou e loli i ko lākou nui. Eia naʻe, ulu mālie nā Pineocytomas. Eia naʻe, he mau kūlana maikaʻi ʻole (ʻaʻole maʻi kanesa) nā mea ʻelua. ʻO ia hoʻi, ʻaʻole lākou he maʻi kanesa.

He aha nā hōʻailona i hoʻokumu ʻia e kēia mau kūlana?

ʻO ka hapa nui o ka manawa, ʻaʻole paha ʻoe e loaʻa i kekahi mau hōʻailona ʻoiai inā he gangliocytoma kou. I kekahi manawa, ʻike nā kauka i kēia mau puʻupuʻu i ka wā e hana ana lākou i nā hoʻokolohua kiʻi (e like me ka MRI a i ʻole CT scan) no kekahi pilikia ʻē aʻe.

Eia nō naʻe, ʻo nā ʻano ʻelua o nā puʻupuʻu, i kapa ʻia ʻo gangliocytoma a me pineocytoma, hiki ke hana i kekahi mau kūlana me nā hōʻailona like ʻole.

Nā hōʻailona maʻamau o Gangliocytoma

Hiki i kēia maʻi ke hana iā ʻoe e ʻike i nā hōʻailona e like me:

• Nā loli i ka neʻe ʻana: E like me ka nalowale o ke kaohi ʻana o nā ʻiʻo. Eia kekahi laʻana, haʻalulu, lolo, nāwaliwali. E noʻonoʻo, ua paʻakikī koke iā ʻoe ke paʻa i ke kīʻaha, a i ʻole e like me kou mau wāwae e kuʻi ana i kou hele ʻana.
• Nā loli o ka manaʻo: He manaʻo o ka mae ʻole ma kekahi mau wahi, e like me ke ʻano ʻūlū ma ka wāwae.
• Nā pilikia ma ka ʻōlelo: ʻŌlelo pahee, me he mea lā ʻaʻole hiki iā ʻoe ke ʻōlelo. ʻAʻole hiki iā ʻoe ke ʻōlelo maopopo i kāu mea e makemake ai e ʻōlelo.
• Nā Hoʻololi ʻIke: Hiki ke lilo ka ʻike i mea pōwehiwehi, e like me he mea lā e ʻike ana ʻoe i ʻelua ʻāpana, a i kekahi manawa e manaʻo paha ʻoe e nalowale ana kekahi hapa o kāu ʻike.

Hiki i ka Gangliocytoma ke hoʻoulu i nā maʻi koʻikoʻi?

ʻAe, hiki i kēia puʻupuʻu ke hana i kekahi mau maʻi koʻikoʻi. Eia kekahi laʻana:

• Nā maʻi o ka ʻōnaehana endocrine:He mau kūlana kēia e kū mai ana i ka wā e piʻi a emi paha ka nui o nā hormones i hana ʻia e nā glands i loko o kou kino. Hiki i kēia ke hoʻopilikia i nā hana he nui o kou kino.
• Nā ʻūlū: Ua lohe paha ʻoe i kēia, ka nalowale koke ʻana o ka ʻike a me nā ʻūlū. Hiki i kēia mau puʻupuʻu ke hana i kēia kūlana ma ka hoʻoulu ʻana i ka lolo.
• Hoʻonui ʻia ke kaomi i loko o ka lolo: Hiki i kēia ke kumu i ka ʻeha poʻo, ka nausea, ka luaʻi ʻana, a me ka huikau. Hiki ke manaʻo ʻia e like me ke kaomi ʻia ʻana o kou poʻo mai loko mai.
• ʻO ka maʻi Lhermitte-Duclos (LDD): He ʻōpū laha ʻole kēia, he ʻino ʻole. Hoʻomohala ia i loko o kou cerebellum. I kekahi manawa ua kapa ʻia ʻo ia he dysplastic gangliocytoma o ka cerebellum. Hiki i ke kanaka me LDD ke loaʻa i nā poʻo ʻeha, ka nausea, ka wai i loko o ka lolo (hydrocephalus), ka paʻakikī i ka hele wāwae a me ka nalowale ʻana o ke kaulike (ataxia), a me nā pilikia ʻike. Hiki i ka poʻe me LDD ke loaʻa i kahi maʻi genetic i kapa ʻia ʻo Cowden syndrome, ka mea e hoʻoulu ai i nā ʻōpū ʻili a me ka piʻi ʻana o ka maʻi kanesa.

Nā hōʻailona maʻamau o Pineocytoma

Hiki i ka Pineocytoma ke hoʻoulu i ka wai e hōʻiliʻili i loko o kou lolo, e hoʻonui ai i ke kaomi. Ua kapa ʻia kēia he hydrocephalus . Inā loaʻa iā ʻoe ka hydrocephalus, hiki iā ʻoe ke ʻike i nā hōʻailona e like me:

• Nā pilikia kaulike: Ke nalowale nei ke kaulike i ka wā e hele ana, me ka manaʻo e hāʻule ana ʻoe.
• Nā pilikia o ka neʻe ʻana o ka maka (ʻParinaud syndrome): Paʻakikī ke nānā i luna, ʻoiai ke nānā pololei i mua. ʻAʻole paha ʻoe e hiki ke hoʻoneʻe i nā maka ʻelua i ka manawa like.
• ʻEha poʻo: Hiki iā ʻoe ke loaʻa i kahi ʻeha poʻo koʻikoʻi a mau loa. I kekahi manawa ʻoi aku ka ʻino o kēia ʻeha ke ala ʻoe i ke kakahiaka.
• Nā pilikia hoʻomanaʻo: Poina i nā mea, pilikia i ka hoʻomanaʻo ʻana i nā mea hou.
• Ka luaʻi a me ka luaʻi: ​​E ʻoi aku ka ʻino o kēia, ʻoiai i ke kakahiaka.
• Nā maʻi hiamoe: ʻAʻole hiki ke hiamoe, a hiamoe nui paha. ʻO kēia no ka mea pili ka pineal gland i ka hiamoe.
• Paʻakikī ke hele wāwae: Manaʻo ia ʻaʻole hiki iā ʻoe ke hele, ke wili nei kou mau wāwae.

He aha ke kumu maoli o kēia mau puʻupuʻu lolo?

E like me ka hapa nui o nā puʻupuʻu ʻē aʻe, ulu nā gangliocytomas a me nā pineocytomas i ka wā e loli ai nā kuhikuhi genetic o kā mākou mau cell. E noʻonoʻo i kēia ʻano: ua like nā cell i loko o ko mākou kino me nā hale hana liʻiliʻi. Loaʻa iā lākou nā kuhikuhi e hana. Ke loli kēia mau kuhikuhi, hoʻomaka nā cell e māhele me ka ʻole o ke kāohi. ʻO ia ka manawa e hana ai lākou i kahi puʻupuʻu.

Eia nō naʻe, ʻaʻole maopopo i nā kānaka noiʻi ke kumu pololei o kēia mau loli. ʻO ia hoʻi, ʻaʻohe pane maopopo no ke aha e hoʻomaka koke ai kēia mau cell e hana pēlā.

Eia nō naʻe, ua ʻike lākou ʻo ka maʻi Cowden, ka mea e pili ana me ka maʻi Lhermitte-Duclos, ua hoʻokumu ʻia e kahi mutation i loko o kahi gene i kapa ʻia ʻo PTEN. Hana kēia gene PTEN i kahi protein e kōkua i ka hoʻomalu ʻana i ke ʻano o ka ulu ʻana a me ka māhele ʻana o nā cell. No laila, ke hoʻololi ʻia ka gene PTEN, ua pau ka hana ʻana o kēlā protein, a hoʻomaka nā cell e ulu me ke kāohi ʻole ʻia.

Pehea e ʻike ai nā kauka i kēia mau puʻupuʻu? (Diagnosis)

Inā loaʻa iā ʻoe kēia mau hōʻailona, ​​e nīnau mua ke kauka iā ʻoe e pili ana i kāu mau hōʻailona a inā paha ua loaʻa i kekahi o kou ʻohana kēia mau kūlana ('mōʻaukala olakino ʻohana'). A laila, e nānā lākou iā ʻoe. E hana lākou i kahi 'hoʻokolohua neurologic', ʻo ia hoʻi kahi hoʻokolohua o kāu ʻōnaehana nerve . E nānā kēia i kēia mau mea:

• Ke ʻano o ka neʻe ʻana o kou mau maka a me kou waha.
• Ikaika o nā ʻiʻo.
• Nā Reflexes (e like me ka lele ʻana o ka wāwae ke kuʻi ʻia ma ke kuli me ka hāmare liʻiliʻi)

Eia kekahi, hiki i ke kauka ke hana i kēia mau hoʻokolohua:

• Magnetic Resonance Imaging (MRI): He hoʻāʻo ʻeha ʻole kēia. Hoʻohana ia i kahi magnet nui, nā nalu lekiō, a me kahi kamepiula e hana i nā kiʻi maopopo loa o nā ʻōpū a me nā ʻano i loko o kou kino. Hoʻohana ʻia ia e ʻike inā he mau puʻupuʻu, pehea ko lākou nui, a me ko lākou wahi.
• ʻO ke kiʻi CT (computed tomography): Hoʻohana kēia i kahi moʻo o nā kukuna X a me kahi kamepiula e hana i nā kiʻi ʻekolu-dimensional o kou mau ʻiʻo palupalu a me nā iwi. E like me MRI, hoʻohana ʻia ia e ʻike a nānā i nā puʻupuʻu.
• Hoʻāʻo koko: Hiki ke hana ʻia kēia e ʻike inā he mau pae maʻamau ʻole o ka melatonin i loko o kou koko (ʻoi aku hoʻi i nā hihia o ka pineocytoma, no ka mea e pili ana i ka pineal gland).
• ʻO ke kī ʻana o ka iwi kuamoʻo (lumbar puncture): Pili kēia i ka lawe ʻana i kahi laʻana o ka wai cerebrospinal (CSF) e hoʻopuni ana i kou lolo a me ke kaula spinal a nānā iā ia no nā cell tumor.
• Biopsy: Pili kēia i ka lawe ʻana i kahi hāpana liʻiliʻi o nā cell mai ka puʻupuʻu a hoʻāʻo iā lākou i loko o kahi keʻena hoʻokolohua e hoʻoholo pono i ke ʻano o ka puʻupuʻu. Hoʻohana pinepine nā kauka i nā ʻano hana minimally invasive e like me ka endoscopy a i ʻole ka stereotactic nila biopsy.

Pehea e mālama ʻia ai ka Gangliocytoma?

E noʻonoʻo he gangliocytoma kou, akā ʻaʻohe ou hōʻailona. I kēlā manawa, e haʻi aku kāu kauka iā ʻoe, "E nānā kākou." ʻO ia hoʻi, e haʻi aku ʻo ia iā ʻoe e hele mai no nā nānā maʻamau e ʻike inā he mau hōʻailona hou kāu, a inā ua loli a ua nui paha ka puʻupuʻu. Hiki iā ia ke hana i nā mea e like me nā hoʻokolohua kiʻi a me nā hoʻokolohua koko.

Akā,Inā makemake ʻoe i ka lāʻau lapaʻau, hana pinepine nā kauka i ke ʻoki lolo e wehe i ka puʻupuʻu. ʻO ka mea pōmaikaʻi, ʻaʻole paha e hoʻi hou mai nā gangliocytomas ma hope o kēia ʻano wehe ʻana.

Pehea e mālama ʻia ai ka Pineocytoma?

I kekahi mau hihia o ka pineocytoma, hiki i nā kauka ke hana i ke ʻoki lolo e wehe i ka ʻāpana a pau o ka puʻupuʻu. Hiki iā lākou ke hoʻohana i kahi lāʻau i kapa ʻia ʻo radiation therapy .

I ka wā o ke ʻoki ʻana, inā loaʻa iā ʻoe ka hydrocephalus (kahi kūlana kahi i piha ai ka lolo i ka wai a ua piʻi aʻe ke kaomi), hiki i nā kauka ke hoʻokomo i kahi ʻōmole palakiko liʻiliʻi i kapa ʻia he shunt i loko o kou lolo. Hoʻopau kēia shunt i ka wai cerebrospinal keu mai kou lolo, e hōʻemi ana i ke kaomi i loko o kou poʻo. Hiki i kēia ke hōʻemi nui i kāu mau hōʻailona.

Aia kekahi ala e hiki ai iā kākou ke pale aku i ke kūkulu ʻia ʻana o kēia mau puʻupuʻu lolo?

ʻĀ, ʻaʻohe mea hiki iā ʻoe ke hana e pale aku i kēia mau puʻupuʻu mai ka hoʻokumu ʻana . E like me ka mea i ʻōlelo ʻia ma mua, hoʻokumu ʻia lākou i ka wā e loli ai nā cell a hoʻomaka e māhele me ke kāohi ʻole. Inā ʻaʻole pili ia i ka maʻi Cowden, ʻaʻole maopopo i nā mea noiʻi ke kumu o kēia loli. Hoʻokumu ʻia ka maʻi Cowden e kahi loli i loko o kahi gene e kaohi ana i ka ulu ʻana o nā cell. No laila, ʻaʻole kēia he mea hiki iā mākou ke kaohi.

He aha ka mea e hana ʻia inā loaʻa iā ʻoe kahi puʻupuʻu e like me kēia? He aha kāu e manaʻo ai?

I ka hapanui o nā hihia, ma hope o ke ʻoki ʻana e wehe i kēia puʻupuʻu, ua haʻahaʻa loa ka manawa e hoʻi hou mai ai . He mea hōʻoluʻolu maoli kēlā, ʻeā? ʻO ia hoʻi, hiki iā ʻoe ke ola i kahi ola maʻamau ma hope o ka mālama ʻana. Eia naʻe, e like me ka ʻōlelo a ke kauka, he mea pono e hele no nā nānā 'follow-up'.

Āhea wau e ʻike ai i ke kauka?

Ma muli o kou kūlana, hiki i kāu kauka ke hoʻonohonoho i nā manawa hoʻopaʻa maʻamau e nānā i kou olakino holoʻokoʻa. Inā ua hana ʻia ʻoe i ke ʻoki ʻana e wehe i kahi puʻupuʻu, hiki iā lākou ke paipai i nā hoʻokolohua kiʻi e nānā inā ua hoʻi mai ka puʻupuʻu a inā paha ua hana ʻia kahi puʻupuʻu hou.

ʻO ka mea nui loa, ʻo ia ke ʻike i ke kauka i kēlā me kēia manawa inā ʻike ʻoe i nā hōʻailona o kahi puʻupuʻu ma mua, a inā ʻike ʻoe i kekahi mau loli hou a kānalua i kou kino . Mai hoʻopanee, ʻeā? No ka mea, ʻo ka wikiwiki o kou ʻike ʻana i ke kūlana, ʻo ka maʻalahi ka mālama ʻana.

Nā mea nui e hoʻomanaʻo mai nā mea a mākou i kūkākūkā ai (Leka Lawe-Home)

ʻO Gangliocytoma lāua ʻo pineocytoma ʻelua mau ʻōpū lolo laha ʻole, lohi ka ulu ʻana, a maikaʻi hoʻi e ulu ana i loko o kāu ʻōnaehana nerve waena (CNS) a me ka pineal gland.

ʻOiai ʻaʻole kēia he maʻi kanesa, hiki iā lākou ke hana i nā ʻano maʻi like ʻole e hiki ke hoʻopilikia i kou ola. Ma muli o ke ʻano o ka puʻupuʻu āu, hiki i nā kauka ke mālama iā ia me ke ʻoki kino a i ʻole ka radiation therapy. He mea paʻakikī loa kēia mau puʻupuʻu e hoʻi hou mai ma hope o ka wehe ʻia ʻana me ke ʻoki kino.

Inā loaʻa iā ʻoe kahi puʻupuʻu maikaʻi e like me kēia, e kamaʻilio me kāu kauka e pili ana i kāu mau koho lapaʻau, nā mea e manaʻo ai ma hope o ka lapaʻau ʻana, a me nā mea e pono ai ʻoe e ʻike e pili ana i ke ola ʻana me kēia ʻano puʻupuʻu. Mai hūnā i kekahi mea, e hoʻolohe i nā mea āpau . E hāʻawi ia iā ʻoe i ka ikaika. Mai makaʻu, ʻo ka mea nui loa, ʻo ia ka makaʻala i kēia mau mea a hahai i nā ʻōlelo a kāu kauka.

ʻO nā puʻupuʻu lolo, gangliocytoma, pineocytoma, CNS, pineal gland, nā hōʻailona, ​​​​​​lāʻau lapaʻau