Ua kuhikuhi anei kāu kauka iā ʻoe i ka hui pū ʻana o nā lāʻau ʻelua i kapa ʻia ʻo Ribociclib lāua ʻo Letrozole no ka maʻi ʻaʻai umauma? Hiki ke hopohopo iki ka ʻike ʻana i kahi lāʻau lapaʻau e like me kēia a hiki ke hāpai i nā nīnau he nui. Akā, mai hopohopo. He mea maʻamau kēia. E kamaʻilio maʻalahi a maopopo kākou e pili ana i kēia mau lāʻau, pehea lākou e pili ai i ke kino, pehea e hoʻohana pono ai iā lākou, a me nā mea e makaʻala ai.
He aha ʻo Ribociclib lāua ʻo Letrozole?
I ka ʻōlelo maʻalahi, ʻelua ʻano lāʻau lapaʻau kēia i hāʻawi ʻia e kāohi i ka ulu ʻana o nā hunaola maʻi umauma. Ke hāʻawi pū ʻia kēia mau mea, kapa mākou iā lākou he mau co-packs.
- Ribociclib: Hana kēia lāʻau lapaʻau ma ke kuhikuhi ʻana i kekahi mau protein i loko o nā hunaola kanesa e kōkua iā lākou e māhele a ulu, a hoʻōki iā lākou mai ka hana ʻana. Hoʻolohi ia i ka ulu ʻana o nā hunaola kanesa.
- Letrozole: Hana kēia lāʻau lapaʻau ma ke kāohi ʻana i ka hana ʻana o ke kino i kahi hormone i kapa ʻia ʻo estrogen. Hoʻohana kekahi ʻano maʻi ʻaʻai umauma i ka estrogen ma ke ʻano he wahie e ulu ai. No laila, ʻoki ʻo Letrozole i kēlā lako wahie.
Hana pū kēia mau lāʻau ʻelua e hoʻouka i nā hunaola kanesa mai nā ʻaoʻao ʻelua a kōkua i ka kaohi ʻana i ko lākou ulu ʻana.
Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau
Ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau, he mea nui loa ia e hoʻomaopopo i kāu kauka e pili ana i kou mōʻaukala olakino piha. E hōʻoia e haʻi iā ia inā loaʻa iā ʻoe kekahi o kēia mau kūlana:
| Kūlana olakino | Wehewehena |
|---|---|
| Maʻi puʻuwai | Inā he moʻolelo kou no kekahi ʻano maʻi puʻuwai a i ʻole ka puʻuwai naʻau kūpono ʻole. |
| Nā maʻi ate | ʻO nā maʻi akepaʻa ma mua a i ʻole i kēia manawa. |
| Nā ʻāpana koko i hoʻemi ʻia | Inā ua ʻike mua ʻia ʻoe me kahi keʻokeʻo koko haʻahaʻa, ke koko koko ʻulaʻula, a i ʻole ka helu platelet. |
| Nā kūlike ʻole o nā minerala | Inā he haʻahaʻa kou mau pae o ka calcium, magnesium, potassium, a i ʻole phosphorus i loko o kou koko. |
| Nā maʻi | ʻO kēlā me kēia maʻi o kēia manawa, ʻoiai nā maʻi viral e like me ka chickenpox a i ʻole herpes. |
| Nā maʻi māmā | Nā maʻi o ka māmā a i ʻole ka hanu e like me ka hānō. |
| Nā kiko ʻē aʻe | E haʻi pū e pili ana i nā iwi nāwaliwali, nā maʻi allergies i nā lāʻau lapaʻau, nā meaʻai, a i ʻole nā mea ʻē aʻe. |
| Hāpai/hānai waiū | Inā ʻoe e hāpai ana, e hoʻāʻo ana e hāpai, a i ʻole e hānai waiū ana, he mea pono loa ia. |
Pehea pololei kaʻu e hoʻohana ai i kēia lāʻau lapaʻau?
No ka loaʻa ʻana o ka hopena maikaʻi loa mai kāu lāʻau lapaʻau, he mea nui loa ia e hoʻohana pono.
- E ale i kēia mau papa me ke aniani wai. Mai kuʻi a nau paha i nā papa.
- E lawe i kāu lāʻau lapaʻau e like me ke kauoha a kāu kauka, i ka manawa i kauoha ʻia. Mai hōʻalo i nā lāʻau.
- Hiki ke lawe ʻia kēia lāʻau lapaʻau ma mua a ma hope paha o ka ʻai ʻana. Eia nō naʻe, inā ʻeha kou ʻōpū, ʻoi aku ka maikaʻi o ka lawe ʻana me ka meaʻai.
- Mea nui: E pale i ka ʻai ʻana i ka pomelo, ka pomeraite, a i ʻole ko lākou wai i ka wā e lawe ana i kēia lāʻau lapaʻau. Hiki i kēia ke hoʻopilikia i ka pono o ka lāʻau lapaʻau.
- Mai ho'ōki i ka lawe ʻana i ka lāʻau me ka ʻole o ke aʻo ʻana a kāu kauka.
Inā manaʻo ʻoe ua lawe nui ʻoe i ka lāʻau lapaʻau, e hele koke i ka Emergency Treatment Unit (ETU) o ka haukapila. A i ʻole e kelepona i ke National Poisons Information Centre ma ka Colombo National Hospital no ka ʻōlelo aʻoaʻo.
He aha kāu e hana ai inā e poina ʻoe i kahi lāʻau a luaʻi paha?
Inā ʻoe e poina i kahi lāʻau lapaʻau, a inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka lāʻau lapaʻau, mai lawe ʻoe i kahi pila ʻē aʻe i kēlā lā . E hōʻalo loa i ka lāʻau lapaʻau i poina a lawe i kāu lāʻau lapaʻau i kou manawa maʻamau i ka lā aʻe. Mai lawe i ʻelua mau lāʻau i ka manawa hoʻokahi.
Nā lāʻau lapaʻau ʻē aʻe ʻaʻole pono e hoʻohana pū ʻia me kēia lāʻau lapaʻau
Hiki i kēia lāʻau lapaʻau ke launa pū me kekahi mau lāʻau lapaʻau ʻē aʻe. No laila, he mea nui e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei (me nā huaora a me nā lāʻau lapaʻau lāʻau) . ʻOi aku hoʻi, pono ʻoe e pale i ka lawe ʻana i kēia mau lāʻau lapaʻau me kēia lāʻau lapaʻau. ʻAʻole paha i piha kēia papa inoa, no laila e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei.
- ʻO kekahi mau lāʻau lapaʻau i lawe ʻia no ka maʻi puʻuwai, ka cholesterol, nā maʻi fungal, a me ka HIV/Hepatitis.
- ʻO kekahi mau lāʻau lapaʻau i hoʻohana ʻia no ka hopu ʻana (e like me ka carbamazepine, phenytoin).
- Nā huahana lāʻau lapaʻau e like me ka `St. John's Wort`.
- Nā lāʻau antibiotic e like me ke ketoconazole a me ka clarithromycin.
- Nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ai i ka hana uila o ka puʻuwai (hoʻolōʻihi ʻia ka manawa QT).
He aha nā mea e noʻonoʻo ai i ka wā e lawe ai i ka lāʻau?
He mea nui loa: Mai hāpai i ka wā e lawe ana i kēia lāʻau lapaʻau a no 3 mau pule ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau. Hiki iā ia ke hōʻeha nui i ka pēpē i hānau ʻole ʻia. Eia kekahi, e pale i ka hānai ʻana i ka waiū i kēia manawa. No nā kāne, hiki i kēia lāʻau lapaʻau ke hoʻopilikia i ka helu sperm, no laila e kamaʻilio me kāu kauka inā ʻoe e noʻonoʻo ana e loaʻa kahi keiki.
- E pale iā ʻoe iho mai nā maʻi: Hiki i kēia lāʻau lapaʻau ke hoʻohaʻahaʻa iki i ka pale ʻana o kou kino. No laila e noho mamao aku mai ka poʻe maʻi. Inā ʻike ʻoe i nā hōʻailona e like me ke kuni, ke anu, a i ʻole ka ʻeha o ka puʻu, mai hoʻōla ponoʻī a haʻi koke i kāu kauka.
- Ke kahe koko a me ka ʻeha: Aia paha ka nui o ka pilikia o ka ʻeha iki a me ke kahe koko. E makaʻala i ka palaki ʻana i kou mau niho a me ka hana ʻana i ka hoʻomaʻemaʻe niho. E haʻi i kāu kauka inā ʻike ʻoe i kekahi kahe koko a ʻeha paha.
- Nā lāʻau hoʻopau ʻeha: Mai lawe i nā lāʻau hoʻopau ʻeha e like me ka aspirin a me ka ibuprofen me ke aʻo ʻole a kāu kauka. Hiki i kēia ke kāohi i nā hōʻailona e like me ke kuni.
- Nā hoʻāʻo koko: E hana kāu kauka i nā hoʻāʻo koko maʻamau e nānā i kāu helu koko a me ka hana o ke akepaʻa i ka wā o ka mālama ʻana. Mai hōʻalo iā lākou.
E makaʻala i nā hopena ʻaoʻao
E like me nā lāʻau lapaʻau āpau, hiki i kēia ke hana i nā hopena ʻaoʻao. ʻAʻole loaʻa i nā kānaka a pau. Akā he mea nui e makaʻala iā lākou.
| Nā hōʻailona e pono e hōʻike koke i kāu kauka | |
|---|---|
| ʻAno | Wehewehena |
| Nā maʻi ʻaleka | ʻŌhūhū ʻili, maneʻo, pehu o ka maka, nā lehelehe a i ʻole ke alelo. |
| Nā hōʻailona o ka hōʻino ʻana o ke akepaʻa | Mimi melemele/ʻeleʻele, melemele o nā maka a i ʻole ka ʻili, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, luaʻi. |
| Nā hōʻailona o ka maʻi | Kuni, anu, ʻeha ka ʻāʻī, kuʻi, maʻi ʻōpū mimi. |
| Nā loli i ka helu o ka puʻuwai | ʻEha ka umauma, ka poniuniu, ka manaʻo e like me ka wikiwiki o ka puʻuwai a i ʻole ke kuʻi ʻano ʻē, ka paʻakikī o ka hanu ʻana. |
| Nā hōʻailona o nā ʻōpū koko | Ka pōkole koke o ka hanu, ka ʻeha o ka umauma, ka pehu a me ka ʻeha ma ka wāwae, ka paʻakikī e ʻōlelo. |
| Nā hōʻailona o ka anemia | Luhi maʻamau ʻole, keʻokeʻo, ʻeha maʻalahi, nā kiko ʻulaʻula ma ka ʻili, ke koko i loko o ka mimi. |
| Nā hōʻailona e hōʻike i ke kauka inā hoʻomau lākou | |
| ʻŌnaehana hoʻoheheʻe | Paʻa ka ʻōpū, kahe ka wai, nausea/luaʻi, ʻeha ka ʻōpū, ʻeha ka waha, nalowale o ka makemake e ʻai. |
| Nā ʻano laulā | ʻEha poʻo, hāʻule ka lauoho, nāwaliwali, hou i ka pō, hiamoe ʻole, pehu o nā lālā. |
Pehea ʻoe e pale ai i kāu lāʻau lapaʻau?
- E mālama i kahi hiki ʻole i nā keiki.
- E mālama i ka lāʻau lapaʻau i loko o ka pahu kumu ma ka mahana o ka lumi ma waena o 20-25 degere Celsius.
- E hoʻolei aku i ka lāʻau lapaʻau i pau ka lā.
He hōʻuluʻulu manaʻo wale nō kēia pepa ʻike. Inā he mau nīnau hou aku kāu e pili ana i kēia lāʻau lapaʻau, e ʻoluʻolu e kamaʻilio me kāu kauka.
Leka Lawe-Home
- E lawe i kāu lāʻau lapaʻau e like me ke kauoha a kāu kauka, i ka manawa kūpono. Mai hōʻalo i nā lāʻau.
- E pale loa i ka hāpai ʻana i ka wā o kēia lāʻau lapaʻau a no 3 mau pule ma hope o ka hoʻōki ʻana.
- E makaʻala no nā hōʻailona o ka maʻi, e like me ke kuni a me ka ʻeha o ka puʻu. Inā ʻike ʻoe i kekahi mea e like me kēia, e hoʻomaopopo koke i kāu kauka.
- E haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau ʻē aʻe āu e lawe ai, nā huaora, a me nā mea hoʻopihapiha āu e lawe ai.
- E hōʻalo i ka inu ʻana i ka pomegerane a me ka pomeraite a i ʻole ko lākou wai.
👩🏽⚕️ Nā nīnau hou aku (FAQs)
💬 He aha ka mea e hoʻohana ʻia ai ʻo Ribociclib lāua ʻo Letrozole / Kisqali Femara Co-Pack?
He hui pū kēia o ʻelua mau lāʻau lapaʻau i hoʻolālā ʻia no ka hoʻomaʻamaʻa ʻana i ka holomua loa e kāohi piha ana i ka 'Advanced/Metastatic Breast Cancer' i nā wahine! Ma ke ʻano kikoʻī, ua hoʻolālā ʻia kēia e hoʻopau i nā aʻa o nā maʻi kanesa e hoʻohana ana i ka hormone wahine 'estrogen' (ER-positive / HER2-negative) e ulu.
💬 Pehea e pepehi ai kēia mau lāʻau ʻelua (Ribociclib + Letrozole) i ka maʻi ʻaʻai umauma?
Hoʻouka kēia i ka maʻi kanesa mai nā ʻaoʻao ʻelua! ʻO ka mea mua, pale ʻo 'Letrozole' i ka hana ʻana o ka 'hormone estrogen' e hānai/hoʻoulu i ka maʻi kanesa 100%, e hoʻopōloli ana i ka maʻi kanesa. A laila, hoʻopau loa ʻo 'Ribociclib' i ʻelua mau mīkini enzyme (CDK4 a me CDK6) e kōkua ana i nā ʻāpana kanesa e māhele koke a ulu. A laila, ua pau ka ulu ʻana o ke kanesa ma laila.
💬 He aha nā hopena ʻaoʻao nui o ka lawe ʻana i kēia mau lāʻau lapaʻau kanesa ikaika?
I ka wā e pepehi ai i nā hunaola kanesa, ua luku ʻia nā 'keʻokeʻo koko/neutrophils (Neutropenia)' a me nā ʻulaʻula koko o ke kino (ʻoi aku ma mua o ka wā ma mua). No laila, ʻoiai he anu liʻiliʻi ka ikaika e hoʻoulu ai i ka niumonia a me ka make! Eia kekahi, no ka mea he kiʻekiʻe ka manawa e hōʻino ai kēia mau pila i ka 'Ake' (Hepatotoxicity), hana mau nā kauka i nā hoʻokolohua koko (LFT). Hiki iā ia ke hoʻololi i ka helu o ka puʻuwai (hoʻolōʻihi QT).
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