Sorafenib: E kamaʻilio kākou e pili ana i kēia lāʻau lapaʻau kūikawā no ka maʻi kanesa? (Sorafenib Oral Tablet)

Ke ʻike ʻia ʻoe a i ʻole kekahi āu i ʻike ai me ka maʻi kanesa a haʻi aku kāu kauka iā ʻoe e hoʻomaka e lawe i kahi lāʻau i kapa ʻia ʻo Sorafenib, he mea maʻamau ke manaʻo iki i ka makaʻu a me ka hoihoi. He aha ke ʻano o kēia lāʻau? Pehea e hana ai? Aia kekahi mau hopena ʻaoʻao? He nui paha kāu mau nīnau e like me kēia i loko o kou manaʻo. No laila i kēia lā, e aʻo kākou i nā mea āpau e pili ana i kēia lāʻau i kapa ʻia ʻo Sorafenib, me he mea lā e kamaʻilio ana ʻoe me kahi hoaaloha.

I ka ʻōlelo maʻalahi, he aha ka Sorafenib?

ʻAʻole like ʻo Sorafenib me nā lāʻau chemotherapy a mākou i ʻike mau ai. He ʻano lāʻau lapaʻau kūikawā ia i kapa ʻia ʻo Targeted therapy . E noʻonoʻo iā ia e like me ka lāʻau chemotherapy maʻamau e like me ka hoʻopōkā ʻana i kahi kūlanakauhale holoʻokoʻa, a hiki iā ia ke luku i nā cell maikaʻi. Akā, ʻo ka Targeted therapy e like me ka ʻimi ʻana i kahi o ka ʻenemi a hoʻouka wale i kēlā wahi.

Hana ʻo Sorafenib ma ke kāohi ʻana i ka hana o nā protein kikoʻī e kōkua ana i nā ʻōpū kanesa e ulu a hana i nā kīʻaha koko. Pale kēia i nā ʻōpū kanesa mai ka ulu ʻana a me ka laha ʻana.

Hoʻohana nui ʻia ia e mālama i ke kanesa o ke akepaʻa , ke kanesa o nā puʻupaʻa , a me ke kanesa o ka thyroid . Ma Sri Lanka, hiki iā ʻoe ke loaʻa kēia lāʻau lapaʻau ma lalo o ka inoa inoa ʻo Nexavar .

Nā mea e pono ai ʻoe e haʻi i kāu kauka ma mua o ka hoʻomaka ʻana i kēia lāʻau lapaʻau

He lāʻau ikaika loa ʻo Sorafenib, no laila he mea nui loa e hāʻawi i kāu kauka i kahi wehewehe piha o kou kūlana olakino. ʻOi loa aku inā loaʻa iā ʻoe kekahi o nā kūlana ma lalo nei, e hōʻoia e haʻi iā lākou e pili ana i ia mea.

He aha ke ala kūpono e lawe ai i ka lāʻau lapaʻau?

Pono e lawe ʻia kēia pila ma ka waha me ke aniani wai.

• Mai uhaʻi, kuʻi, a nau paha i ka papa. E ale holoʻokoʻa.
• ʻO ka mea nui loa: Pono e lawe ʻia kēia ma ka ʻōpū ʻole . ʻO ia hoʻi, ma ka liʻiliʻi he hoʻokahi hola ma mua a ʻelua paha hola ma hope o ka ʻai ʻana. ʻO ka lawe ʻana me ka meaʻai e hōʻemi i ka omo ʻana o ka lāʻau lapaʻau i loko o ke kino.
• E lawe i kāu lāʻau lapaʻau e like me ke kauoha a kāu kauka, i ka manawa i kauoha ʻia. Mai hoʻōki i ka lawe ʻana iā ʻoe iho. Mai hoʻōki i ka lāʻau lapaʻau me ka ʻole o ke aʻo ʻana a ke kauka.

He aha kāu e hana ai inā e poina ʻoe i kahi mahele o ka lāʻau lapaʻau?

Inā ʻoe e poina i kahi lāʻau lapaʻau, e lawe koke iā ia i kou hoʻomanaʻo ʻana. Akā inā kokoke ka manawa no kāu lāʻau lapaʻau aʻe, e kāpae i ka lāʻau lapaʻau i poina a lawe i kāu lāʻau lapaʻau aʻe i ka manawa i hoʻonohonoho ʻia. Mai lawe i ʻelua lāʻau lapaʻau i ka manawa hoʻokahi.

Hiki paha ke loaʻa nā pilikia me nā lāʻau lapaʻau ʻē aʻe? (Nā Hana Pilikino Lāʻau Lapaʻau)

ʻAe, he lāʻau lapaʻau ʻo Sorafenib e hiki ke launa pū me nā lāʻau lapaʻau ʻē aʻe. No laila, pono ʻoe e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei, me nā mea i kuhikuhi ʻia e kāu kauka, nā mea i kūʻai ʻia ma ka hale kūʻai lāʻau lapaʻau, nā lāʻau lapaʻau kuʻuna, nā huaora, a me nā mea hoʻohui lāʻau.

ʻOi aku hoʻi, e pale i ka lawe ʻana iā Sorafenib me nā lāʻau lapaʻau e hiki mai ana:

• ʻO Cisapride
• ʻO Dronedarone
• Pimozide
• ʻO Thioridazine

Eia kekahi, he mea nui e hoʻomaopopo i kāu kauka inā ʻoe e lawe ana i nā lāʻau lapaʻau aʻe, no ka mea, hiki iā lākou ke launa pū me Sorafenib.

• Nā lāʻau lapaʻau anticonvulsant (e.g. Carbamazepine, Phenobarbital, Phenytoin)
• Nā ʻano antibiotic (e.g. Rifampin, Rifabutin)
• ʻO Dexamethasone (kahi ʻano steroid)
• ʻO Digoxin (he lāʻau lapaʻau no ka maʻi puʻuwai)
• ʻO ka huahana lāʻau lapaʻau ʻo St. John's Wort
• Nā lāʻau lapaʻau ʻē aʻe e hoʻopilikia ai i ka helu o ka puʻuwai (e hoʻopilikia ana i ka wā QT)
• ʻO Vinblastine (kekahi lāʻau lapaʻau anticancer)

ʻAʻole i piha kēia papa inoa, no laila e haʻi i kāu kauka e pili ana i nā lāʻau lapaʻau āpau āu e lawe nei.

Nā mea e hoʻomanaʻo ai i ka wā e lawe ai i ka lāʻau lapaʻau

Ka hāpai ʻana a me ka hānau keiki ʻana

ʻO kēia ka mea nui loa e makaʻala ai.

• Nā wāhine: Mai hāpai i ka wā e lawe ana i kēia lāʻau lapaʻau. ʻAʻole kūpono ke hāpai a hiki i 6 mau mahina ma hope o ka hoʻōki ʻana i ka lāʻau lapaʻau. E kamaʻilio me kāu kauka e pili ana i ke ʻano hana hoʻomalu hānau kūpono loa.
• Nā Kāne: Inā ʻoe e lawe ana i kēia lāʻau lapaʻau, pono ʻoe e pale i ka hānau ʻana i kahi keiki i ka wā e lawe ana i ka lāʻau lapaʻau a no 3 mau mahina ma hope o ka hoʻōki ʻana. He mea nui e hoʻohana ʻoe a me kāu hoa i kahi ʻano kaohi hānau kūpono loa.

ʻO ke ʻoki kino a me ka ho'ōla ʻana i nā ʻeha

Inā ʻoe e hana ana i kekahi ʻoki kino a hana niho paha, e haʻi mua i kāu kauka a kauka niho paha e lawe ana ʻoe iā Sorafenib. No ka mea e hoʻolohi kēia lāʻau i ke kaʻina hana ho'ōla, hoʻomaka pinepine ʻia ia i 2 mau pule ma hope o ke ʻoki kino nui.

Ke kahe koko a me nā maʻi

Hiki i kēia lāʻau lapaʻau ke hoʻoulu i ka ʻeha a me ke kahe ʻana o ke koko, a hiki nō hoʻi ke hōʻemi i ka hiki o ke kino ke hakakā i nā maʻi.

• Inā ʻike ʻoe i kekahi kahe koko ʻē (e like me ke kahe ʻana o ke koko mai ka ʻāʻī, ka ihu), e haʻi i kāu kauka.
• E akahele i ka palaki ʻana i kou mau niho a me ka hoʻohana ʻana i nā niho ʻūpā.
• Inā loaʻa iā ʻoe nā hōʻailona e like me ke kuni, ke anu, a i ʻole ka ʻeha o ka puʻu, mai hoʻōla ponoʻī a kamaʻilio me kāu kauka. E pale i nā wahi e ʻākoakoa ai ka poʻe maʻi.

He aha nā hopena ʻaoʻao e hiki mai ana?

E like me nā lāʻau lapaʻau āpau, hiki iā Sorafenib ke loaʻa nā hopena ʻaoʻao. ʻAʻole loaʻa i nā kānaka a pau, akā he mea nui e makaʻala iā lākou.