Tamoxifen - ʻO ka mea e pono ai ʻoe e ʻike e pili ana i kēia lāʻau lapaʻau maʻi umauma

Ke haʻi aku ke kauka iā ʻoe a i ʻole kahi mea aloha iā ʻoe he "maʻi ʻaʻai umauma " kou, he mea maʻamau ke manaʻo ua hiolo kou honua holoʻokoʻa. Me ka makaʻu a me ka hopohopo e hiki mai ana i ka noʻonoʻo, he tausani mau nīnau kāu e pili ana i ka lāʻau lapaʻau a me ka lāʻau lapaʻau a ke kauka e kuhikuhi ai. "He maikaʻi anei kēia lāʻau lapaʻau no ke kino?", "E hoʻoulu anei i nā hopena ʻaoʻao ?", "E hana maoli anei kēia?" Ke holo nei paha nā mea e like me ia ma kou poʻo. Pēlā mākou e kamaʻilio ai e pili ana iā Tamoxifen, kahi lāʻau lapaʻau koʻikoʻi i hoʻohana nui ʻia i ka mālama ʻana i ka maʻi ʻaʻai umauma, ma ke ʻano maʻalahi a aloha i kēia lā.

I ka ʻōlelo maʻalahi, he aha ka Tamoxifen?

He lāʻau lapaʻau ʻo Tamoxifen i hoʻohana ʻia e mālama i ka maʻi ʻaʻai umauma hormone receptor-positive . Loaʻa ia ma ke ʻano he pila (Nolvadex®) a i ʻole he wai (Soltamox®).

I kēia manawa, ke noʻonoʻo nei paha ʻoe, "He aha kēia maʻi kanesa e hilinaʻi ana i ka hormone?" He mea maʻalahi loa ia. Ua like kekahi mau hunaola kanesa i loko o ko kākou kino me kahi mea kanu liʻiliʻi. E like me ka mea kanu e pono ai ka wai a me ka meaʻai e ulu a ulu, pono kēia mau hunaola kanesa i nā hormones i kapa ʻia ʻo estrogen a i ʻole progesterone e ulu a laha. ʻO ia ka mea a mākou e kapa nei he 'maʻi kanesa e hilinaʻi ana i ka hormone.'

ʻO ka hana a ka lāʻau tamoxifen, ʻo ia ke ālai i ka hana o ka hormone estrogen e pono ai nā hunaola kanesa. Ua like ia me ke pani ʻana i ka piula wai no kahi mea kanu. A laila, ʻaʻole i loaʻa i nā hunaola kanesa ka leka e pono ai lākou e ulu.

Eia kekahi, ʻōlelo pinepine nā kauka i kēia lāʻau lapaʻau e pale aku i ka maʻi kanesa i ka poʻe i loaʻa i ka pilikia nui o ka loaʻa ʻana o ka maʻi kanesa o ka umauma (no ka laʻana, inā ua loaʻa i kekahi o ka ʻohana ka maʻi kanesa ).

No wai kēia lāʻau lapaʻau i ʻōlelo ʻia?

ʻAʻole hāʻawi ʻia ʻo Tamoxifen i nā poʻe maʻi kanesa umauma āpau. E noʻonoʻo kāu kauka i nā kumu he nui, me kou mōʻaukala olakino a me ke ʻano o ke kanesa, e hoʻoholo ai inā kūpono kēia lāʻau lapaʻau iā ʻoe. Hoʻohana nui ʻia ia i nā hihia aʻe:

• ʻO ka poʻe me ka mōʻaukala ʻohana o ka maʻi kanesa a i ʻole nā ​​​​hoʻololi ʻana o ka gene BRCAMa ke ʻano he ana e pale aku ai i ka maʻi kanesa i ka poʻe i loaʻa i ka pilikia nui o ka loaʻa ʻana o ka maʻi kanesa o ka umauma ma muli o nā kumu e like me:
• Kāohi i ka hoʻi hou ʻana o ke kanesa i kekahi i loaʻa mua i ke kanesa o ka umauma a ua hana ʻia i ka lāʻau lapaʻau e like me ke ʻoki kino , chemotherapy , a i ʻole ka radiation therapy .
• E pale i ka maʻi kanesa ma kekahi umauma olakino no kekahi mea i loaʻa i ka maʻi kanesa ma kekahi umauma.
• No kekahi kanaka me ke kahua mua loa o ka maʻi kanesa, e like me DCIS (ductal carcinoma in situ) , e pale iā ia mai ka laha hou ʻana a lilo i maʻi kanesa ʻoi aku ka koʻikoʻi.

He aha nā pōmaikaʻi nui o Tamoxifen?

He lāʻau lapaʻau ʻo Tamoxifen i kōkua i ka hoʻopakele ʻana i nā ola o nā miliona o nā wahine a puni ka honua no nā makahiki he ʻumi. ʻAʻole liʻiliʻi nā pono o kēia.

• Hoʻēmi i ka hoʻi hou ʻana o ke kanesa: Hiki i kēia lāʻau lapaʻau ke hōʻemi i ka pilikia o ka hoʻi hou ʻana o ke kanesa ma hope o ka mālama ʻana ma o 30% a 50% .
• Mālama i ka umauma ʻē aʻe: No kekahi mea i loaʻa i ka maʻi kanesa ma kekahi umauma, ua hoʻemi ʻia ka pilikia o ka loaʻa ʻana o ka maʻi kanesa ma kekahi umauma ma kahi o 50% .
• Kāohi i ka maʻi ʻaʻai: No kekahi kanaka i loaʻa i ka pilikia kiʻekiʻe, hiki ke hoʻemi ʻia ka pilikia o ka loaʻa ʻana o ka maʻi ʻaʻai ma kahi mua ma kahi o 40% .
• Hoʻoikaika i nā iwi: Kōkua kēia lāʻau lapaʻau i ka pale ʻana i ka osteoporosis , kahi maʻi lahilahi o ka iwi e kū mai ana ma hope o ka menopause.
• Hoʻohaʻahaʻa i ka cholesterol: Loaʻa iā Tamoxifen ka hiki ke hoʻemi i ka pae o ka cholesterol maikaʻi ʻole i loko o ke kino.

He aha nā hopena ʻaoʻao e hiki ke loaʻa mai ka lawe ʻana i ka Tamoxifen?

E like me nā lāʻau lapaʻau āpau, hiki i ka Tamoxifen ke hana i kekahi mau hopena ʻaoʻao. Akā, ʻaʻole kēia manaʻo e ʻike ʻoe iā lākou āpau. ʻAʻole paha e manaʻo kekahi poʻe i kekahi. Hiki i kekahi ke ʻike i hoʻokahi a ʻelua paha. ʻO ka ʻike ʻana i kēia mau mea ma mua e kōkua iā ʻoe e hoʻoponopono iā lākou.

E māhele kākou i kēia mau hopena ʻaoʻao i ʻelua ʻāpana.

I ka manawa hea e pono ai ʻoe e kāhea koke aku i ke kauka?

Inā ʻoe e lawe ana iā Tamoxifen a loaʻa iā ʻoe kekahi o nā hōʻailona ma lalo nei, pono ʻoe e hoʻomaopopo koke i kāu kauka a i ʻole e hele i ka Emergency Department (ETU) o ka haukapila kokoke loa iā ʻoe.

• Inā ʻeha kou umauma a paʻakikī paha ka hanu ʻana .
• Inā loaʻa iā ʻoe ke kuni .
• Inā loaʻa iā ʻoe nā hōʻailona o ka hahau ʻana - no ka laʻana, ka ʻōlelo slurred, ka hihiʻo blurred, a i ʻole ka numbness koke ma kekahi ʻaoʻao o ke kino (lima, wāwae, a maka paha).
• Inā pehu koke kou mau wāwae, kuʻekuʻe wāwae, a i ʻole nā ​​​​wāwae (ʻoi aku hoʻi i hoʻokahi wāwae).
• Inā ʻaʻole hiki iā ʻoe ke hoʻōki i ka luaʻi ʻana .
• Inā he kahe koko ʻē kou.

ʻO kekahi mau nīnau maʻamau e pili ana iā Tamoxifen

He lāʻau lapaʻau chemotherapy anei ʻo Tamoxifen?

ʻAʻole. ʻO kēia kahi e huikau ai ka poʻe he nui. He lāʻau lapaʻau hormonal ʻo Tamoxifen. No loko ia o kahi papa o nā lāʻau i kapa ʻia ʻo Selective Estrogen Receptor Modulators (SERMs) . ʻO Chemotherapy kahi lāʻau lapaʻau e pepehi i nā cell e māhele wikiwiki ana (nā cell maʻi ʻaʻai a me nā cell olakino). Akā hana ʻokoʻa ʻo Tamoxifen, ma ka pae hormonal.

He palekana anei ka lawe ʻana iā Tamoxifen i ka wā hāpai?

ʻAʻole loa. ʻO ka hāpai ʻana i ka wā e lawe ana i ka tamoxifen hiki ke hana i nā kīnā hānau koʻikoʻi. No laila, inā ʻoe e lawe ana i kēia lāʻau lapaʻau, pono ʻoe e pale i ka hāpai ʻana . ʻAʻole kūpono ka kaohi hānau hormonal (e like me nā pila kaohi hānau) i kēia manawa, no laila e kamaʻilio me kāu kauka e pili ana i ka hoʻohana ʻana i kahi ʻano kaohi hānau ʻaʻole hormonal (e like me nā condom a i ʻole IUD). He mea nui e hoʻohana i ka kaohi hānau no ʻelua mahina ma hope o ka hoʻōki ʻana i ka lāʻau.

He aha nā meaʻai a me nā mea inu e pono ke pale ʻia i ka wā e lawe ana iā Tamoxifen?

ʻAe. Hiki i kekahi mau meaʻai a me nā mea inu ke hōʻemi i ka pono o Tamoxifen. No laila, ʻoi aku ka maikaʻi o ka pale ʻana i kēia mau mea:

• ʻAlapalapala
• Nā Tangerines
• ʻAila o kēlā me kēia ʻano

Loaʻa koke nā hopena ʻaoʻao ma hope o ka hoʻomaka ʻana e lawe i ka lāʻau lapaʻau?

ʻOkoʻa kēia mai kēlā kanaka a kēia kanaka. Hiki i kekahi poʻe ke hoʻomaka e ʻike i nā loli liʻiliʻi mai ka lā a lākou e lawe ai i ka pila mua. ʻO kekahi poʻe ʻaʻole paha e ʻike i kekahi mea no nā mahina.

ʻEhia ka lōʻihi o ke ola ʻana o ka lāʻau lapaʻau ma ke kino ma hope o ka hoʻōki ʻana?

Noho ka hana o Tamoxifen i loko o ke kino no ʻelua pule ma hope o kou lawe ʻana i ka pila hope loa, akā hiki ke hala ma kahi o ʻekolu mahina no ka haʻalele loa ʻana mai kou kino.