Ua luhi anei ʻoe i ka maʻi mau ʻana me ke anu , ka ʻū, a me ka maʻi palū? I kekahi manawa manaʻo mākou, "Auē, ua nāwaliwali koʻu kino." Akā, ʻaʻole ia ke kumu i nā manawa a pau. I kekahi manawa, ʻo ke kumu o kēia he nāwaliwali i ka ʻōnaehana pale o ko mākou kino, ʻo ia hoʻi, ka ʻōnaehana pale. I kēia lā, e kamaʻilio mākou e pili ana i ia ʻano maʻi, kahi maʻi i kapa ʻia ʻo CVID , hiki ke hoʻopilikia nui i ko mākou ola o kēlā me kēia lā.
He aha ka CVID?
I ka ʻōlelo maʻalahi, ʻo CVID (Common Variable Immunodeficiency) he maʻi genetic e pili ana i ka ʻōnaehana pale o ko mākou kino. No loko ia o ka māhele o nā maʻi i kapa ʻia ʻo 'primary immunodeficiency disease (PIDD)'.
E noʻonoʻo e like me kahi pā kaua. Loaʻa i kēia pā kaua nā koa e pale aku iā ia mai nā ʻenemi i kapa ʻia he germs . ʻO kēia mau koa ka mea a mākou e kapa nei he antibodies i ka lāʻau lapaʻau. ʻO ke kanaka me CVID e hana i kēia mau antibodies ma nā pae haʻahaʻa loa. No laila, he aha ka mea e hana ai ke emi ka helu o nā koa i loko o ko mākou pā kaua? Hiki i nā ʻenemi haole, ʻo ia hoʻi nā germs, ke komo maʻalahi i ke kino a hoʻoulu i nā maʻi .
ʻO ka hopena, loaʻa pinepine i ka poʻe me CVID nā maʻi pepeiao , nā maʻi sinus , a me nā maʻi māmā . Hoʻonui pū ke kūlana i ka pilikia o nā kūlana koʻikoʻi, e like me nā pilikia ʻōpū, nā maʻi koko a me nā maʻi autoimmune , a me ke kanesa .
ʻO wai ka mea i ʻoi aku ka nui o ka pilikia o ka hoʻomohala ʻana i ka CVID?
Ke hoʻohālikelike ʻia me nā maʻi ʻē aʻe o ka pale ʻana i ka maʻi, he maʻi maʻamau ka CVID. Ma ka awelika, hoʻopilikia ia ma kahi o hoʻokahi i loko o 25,000 mau kānaka.
ʻOiai hiki ke hoʻopilikia i kekahi, ʻoi aku ka maʻamau i nā pākeke. ʻOiai hiki i ka CVID ke hoʻopilikia i nā keiki a me nā ʻōpio, ʻike pinepine ʻia i ka wā makua. ʻIke pinepine ʻia ka maʻi ma waena o 20 a me 50 mau makahiki .
Eia nō naʻe, ua hōʻike ʻia nā noiʻi ua ʻike ʻia ma kahi o 2 i loko o 10 mau kānaka me CVID me ka immunodeficiency i ka wā kamaliʻi.
He aha ke kumu o ka CVID?
ʻO kaʻoiaʻiʻo, ʻaʻole maopopo i nā kauka ke kumu o ka hapa nui o nā maʻi CVID e hoʻomohala ai i kēia ʻano.
Eia nō naʻe, no kahi o hoʻokahi i loko o 10 mau kānaka me CVID, he hoʻoilina ke kumu. ʻO ke ʻano kēia, hiki ke hana ʻia ke kūlana e kahi hoʻololi genetic i loko o kāu DNA . I ka ʻōlelo maʻalahi, ua hoʻoilina paha ʻoe i ke kūlana mai kou makuahine, makuakāne, a i ʻole kekahi lālā ʻohana.
Hiki ke hana ʻia ʻo CVID e nā kīnā genetic i loko o ka ʻōnaehana pale. ʻO kēia mau hemahema ke kumu o ke kino e hana i nā pae haʻahaʻa loa o nā immunoglobulins, kahi ʻano protein e hakakā ana i nā germs, a ʻoi aku hoʻi, nā antibodies i kapa ʻia ʻo immunoglobulin G (IgG). Hoʻonāwaliwali kēia i ka ʻōnaehana pale. I kekahi manawa, hiki ke ulu aʻe kēia maʻi ma hope o ke ola.
He aha nā hōʻailona o CVID?
Hiki ke ʻokoʻa nā hōʻailona o CVID mai kēlā kanaka a kēia kanaka. Loaʻa i kekahi poʻe nā hōʻailona liʻiliʻi, aʻo kekahi poʻe hiki ke loaʻa nā hōʻailona koʻikoʻi loa. Aia ia i ka nāwaliwali o kou ʻōnaehana pale.
Hōʻike ka papa ma lalo nei i kekahi o nā hōʻailona maʻamau o CVID.
| Hōʻailona | Wehewehena |
|---|---|
| Nā maʻi ʻōnaehana hanu | ʻO ke kuʻi pinepine a lōʻihi, ka paʻakikī o ka hanu ʻana, a me nā maʻi o ka māmā (hiki ke alakaʻi i nā maʻi e like me ka bronchitis a i ʻole ka pneumonia). |
| Nā maʻi pepeiao a me nā sinus | Nā maʻi pepeiao pinepine a me nā maʻi sinus. |
| Nā pilikia o ka ʻōnaehana hoʻoheheʻe | Ka maʻi pākī, ka nausea, ka luaʻi ʻana, a me ka pohō kaumaha i wehewehe ʻole ʻia. |
| Nā hono a me ka spleen | Ka pehu ʻana a me ka ʻeha ma nā hono e like me nā kuli, nā kuʻekuʻe lima, a me nā pulima lima. Ka hoʻonui ʻia ʻana o ka spleen. |
| Nā hiʻohiʻona ʻē aʻe | Nā pilikia o ka hana o ke akepaʻa, nā platelets koko haʻahaʻa, a me nā hopena maʻamau ʻole a koʻikoʻi paha i nā lāʻau pale. |
Pehea e ʻike ʻia ai ka CVID?
Inā loaʻa mau iā ʻoe nā maʻi pepeiao, sinus, a i ʻole nā maʻi māmā, a inā he hopena ʻē kāu i nā lāʻau pale i ʻōlelo pinepine ʻia, e hoʻomaopopo pono i kāu kauka.
Ke haʻi aku ʻoe i kāu kauka e pili ana i kēia mau hōʻailona, hiki iā ia ke kānalua iā CVID. No ka hōʻoia ʻana i ka hōʻailona, e nīnau ʻo ia e pili ana i kou mōʻaukala olakino a me ka mōʻaukala olakino o kou ʻohana. A laila, e kauoha lākou i kekahi mau hoʻokolohua koko. Hiki i kēia mau hoʻokolohua koko ke nānā i ka haʻahaʻa o nā antibodies o kou kino a me ka maikaʻi o ka hana ʻana o kāu ʻōnaehana pale.
I kekahi manawa, hāʻawi paha kāu kauka iā ʻoe i kahi lāʻau pale no kekahi maʻi ʻē aʻe a hoʻāʻo e ʻike inā piʻi maʻamau nā pae antibody o kou kino i ka pane.
Aia kekahi lāʻau lapaʻau no CVID?
ʻAʻohe lāʻau lapaʻau no CVID i kēia manawa. Akā, mai hopohopo. Hiki iā ʻoe ke mālama pono i ke kūlana, pale iā ʻoe iho mai nā maʻi, a ola i kahi ola maʻamau a olakino.
ʻO ka lāʻau lapaʻau nui, ʻo ia ka immunoglobulin (IgG) replacement therapy . Pili kēia i ka hāʻawi ʻana i ka mea maʻi i nā antibodies IgG, i loaʻa mai nā mea hāʻawi koko olakino. Hoʻonui kēia i ka pae o nā antibodies i loko o kou kino a hoʻoikaika i ka ʻōnaehana pale.
Hiki ke loaʻa kēia lāʻau lapaʻau ma nā ʻano ʻelua:
1. Ke ʻano IV: Ma ke ʻano he wai saline i hāʻawi ʻia i loko o kahi aʻa (IV) i hoʻokahi manawa i ka mahina.
2. Ke ʻano hana subcutaneous: Ma ke ʻano he inikini ma lalo o ka ʻili i hoʻokahi manawa i ka pule a i ʻole i kēlā me kēia ʻelua pule.
ʻO ka mea nui, pono e lawe ʻia kēia lāʻau no ke ola a pau.
ʻAʻole ʻike ka hapa nui o ka poʻe i nā hopena koʻikoʻi mai kēia lāʻau lapaʻau. Eia nō naʻe, hiki i kekahi ke loaʻa i nā ʻeha poʻo a i ʻole nā hopena alerika. E kamaʻilio me kāu kauka e hoʻoholo i ka lāʻau lapaʻau kūpono loa iā ʻoe.
Eia kekahi, inā loaʻa iā ʻoe kahi maʻi, e kuhikuhi kāu kauka i nā lāʻau antibiotics a i ʻole nā lāʻau antiviral e mālama ai.
Nā pilikia ʻē aʻe e hiki ke kū mai ma muli o CVID
Ma muli o ka hana pono ʻole o ka ʻōnaehana pale, ʻoi aku ka nui o ka pilikia o ka poʻe me CVID i ka hoʻomohala ʻana i nā maʻi koʻikoʻi ʻē aʻe.
- Nā maʻi Autoimmune: ʻO kēia ka manawa e hoʻouka hewa ai ka ʻōnaehana pale o ke kino i kāna mau hunaola olakino ponoʻī. Hiki i kēia ke hana i nā kūlana e like me ka 'autoimmune hemolytic anemia' (ka luku ʻia ʻana o nā hunaola koko ʻulaʻula olakino), 'rheumatoid arthritis' (arthritis), a me 'thrombocytopenia' (nā platelets koko haʻahaʻa).
- Kanesa: Hoʻonui ka CVID i ka pilikia o ka hoʻomohala ʻana i kekahi mau ʻano kanesa, e like me ka lymphoma a i ʻole ke kanesa ʻōpū.
- Bronchiectasis: Hiki i nā maʻi māmā pinepine ke hōʻino i nā ala ea i loko o nā māmā a hoʻonui mau iā lākou. Hiki i kēia ke alakaʻi i ka ʻū mau me ka mucus a hoʻolilo iā ia i mea paʻakikī ke hoʻomaʻemaʻe i ka mucus.
- Nā Granulomas: He mau puʻupuʻu liʻiliʻi kēia i hana ʻia e ka hōʻiliʻili ʻana o nā hunaola koko keʻokeʻo. ʻIke pinepine ʻia lākou i loko o nā māmā, ka ʻili, a i ʻole nā ʻōpū ʻē aʻe.
Leka Lawe-Home
- He maʻi ʻano genetic ka CVID e hoʻonāwaliwali ai i ka ʻōnaehana pale ma muli o ka haʻahaʻa o nā pae antibodies i hana ʻia e ke kino.
- ʻO nā maʻi pepeiao, sinus, a me nā māmā pinepine nā hōʻailona nui.
- Inā loaʻa iā ʻoe a i ʻole kekahi āu i ʻike ai kēia mau hōʻailona, e ʻike koke i ke kauka no ka ʻōlelo aʻo.
- ʻOiai ʻaʻole hiki ke ho'ōla loa ʻia ka CVID, hiki ke mālama maikaʻi ʻia me ka mālama ʻana i ka antibody no ke ola holoʻokoʻa (IgG therapy).
- Inā loaʻa iā ʻoe ʻo CVID, he mea nui loa ia e mālama i nā ʻano hoʻomaʻemaʻe maikaʻi, e like me ka holoi pinepine ʻana i kou mau lima, i mea e pale ai iā ʻoe iho mai nā germs.
CVID, ʻO ka hemahema o ka pale ʻana i nā loli maʻamau, ka pale ʻana, ka maʻi pinepine, nā maʻi, nā antibodies, ka lāʻau lapaʻau IgG
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