Koj puas tau pom ib tug neeg ncab lawv txhais tes tawm ntawm lawv xub ntiag, thiab tam sim ntawd lawv txhais tes poob qis thiab rov qab los dua yam tsis muaj kev tswj hwm? Nws zoo li tus npauj npaim co nws tis. Tej zaum koj twb tau ntsib qhov no koj tus kheej lawm. Qhov no tsis yog kev co ib txwm muaj. Hauv kev kho mob, peb hu nws tias Asterixis. Nws tsis yog kab mob tiag tiag, tab sis yog ib qho tsos mob ntawm tus mob. Yog li ntawd vim li cas qhov no thiaj tshwm sim? Qhov no puas yog ib yam dab tsi uas yuav tsum ntshai? Cia peb tham txog qhov no yooj yim thiab meej.
Asterixis yog dab tsi tiag?
Hais yooj yim xwb, asterixis yog thaum koj siv ib lub leeg (piv txwv li, thaum koj ncab ib sab caj npab mus tom ntej), lub leeg ntawd yuav so ib pliag. Qhov no yog vim muaj kev cuam tshuam luv luv hauv cov teeb liab los ntawm lub hlwb.
Xav txog koj tab tom thawb rau ntawm phab ntsa. Yuav ua li cas yog tias cov leeg ntawm koj txhais caj npab so sai sai tsawg dua ib pliag? Koj txhais caj npab txav mus tom ntej thiab tom qab ntawd rov qab mus rau nws qhov chaw qub? Asterixis yog ib yam dab tsi zoo li ntawd. Lwm lub npe peb muab rau qhov no hauv kev kho mob yog `(Negative myoclonus)`. Ntawm no, ``Negative'' tsis siv rau hauv lub ntsiab lus ntawm ``phem''. Feem ntau, thaum cov leeg nqaij ntswj, peb hais tias ``(Positive myoclonus)``, uas txhais tau tias ``kev ua ub no ntau ntxiv.'' Qhov tshwm sim ntawm no yog tias cov leeg nqaij uas twb ua haujlwm lawm nres ib pliag, yog li nws hu ua ``(Negative myoclonus)``, uas txhais tau tias ``kev ua ub no txo qis.''
Tus mob no tuaj yeem tshwm sim los ntawm teeb meem uas cuam tshuam ncaj qha rau lub hlwb, lossis nws tuaj yeem tshwm sim ua tus mob thib ob uas cuam tshuam rau lub hlwb vim muaj teeb meem lwm qhov hauv lub cev (piv txwv li, siab, raum).
Koj paub ib tug neeg uas muaj asterixis li cas?
Feem ntau Asterixis cuam tshuam rau ob sab ntawm lub cev. Txawm li cas los xij, nws qee zaum tsuas yog cuam tshuam rau ib sab lossis ntau dua ib sab. Nrog rau cov tsos mob no, cov tsos mob xws li qaug zog, tsis meej pem, thiab tsis paub qhov chaw thiab lub sijhawm kuj pom.
Muaj ob txoj kev tseem ceeb uas tus kws kho mob yuav kuaj xyuas qhov no:
1. Txoj kev siv tes tuav: Koj tus kws kho mob yuav qhia koj kom tuav koj txhais tes ncaj nraim rau ntawm koj xub ntiag, xib teg tig mus deb ntawm koj, zoo li koj tab tom thaiv phab ntsa uas tsis pom. Koj cov ntiv tes yuav tsum tau nthuav dav sib nrug. Yog tias koj tuav txoj haujlwm no li 30 vib nas this thiab koj txhais tes cia li 'nrov' thiab tom qab ntawd rov qab los yam tsis muaj koj tswj, nws yuav yog asterixis.
2. Txoj kev tuav: Hauv txoj kev no, koj raug hais kom tuav koj txhais tes ntawm tus kws kho mob kom nruj. Thaum ua li ntawd, tus kws kho mob yuav hnov yog tias koj qhov kev tuav maj mam qaug zog thiab qaug zog.
Qhov tseem ceeb yog tias cov tsos mob ntawm Asterixis tej zaum yuav tsis pom tseeb tam sim ntawd thaum lub sijhawm kuaj no. Yog li ntawd, tus kws kho mob yuav hais kom koj nyob hauv qhov chaw ntawd tsawg kawg ib feeb.
Vim li cas tus kab mob Asterixis no thiaj tshwm sim? Cov laj thawj tseem ceeb yog dab tsi?
Muaj ntau yam ua rau asterixis tshwm sim. Qhov laj thawj tseem ceeb yog vim tias cov kab mob tseem ceeb hauv peb lub cev tsis ua haujlwm zoo. Cia peb saib seb cov laj thawj no yog dab tsi.
| Pawg laj thawj | Piav qhia yooj yim |
|---|---|
| Teeb meem siab thiab raum | Lub siab thiab lub raum lim cov tshuaj lom tawm ntawm peb cov ntshav. Thaum cov kabmob no tsis ua haujlwm zoo, cov tshuaj lom ntawd yuav sib sau ua ke hauv cov ntshav. Vim tias cov tshuaj lom no rhiab heev rau lub hlwb, lawv tuaj yeem ua rau cov hlwb puas tsuaj thiab ua rau lub hlwb tsis ua haujlwm zoo. Cov mob xws li ua tsis tau haujlwm ntawm lub siab, ua tsis tau haujlwm ntawm lub raum, thiab mob cirrhosis tuaj yeem ua rau qhov no . |
| Kev puas tsuaj rau lub hlwb | Kev raug mob lossis kab mob ntawm lub hlwb tuaj yeem ua rau muaj kev puas tsuaj (mob) rau qee qhov chaw ntawm lub hlwb. Yog tias cov mob no cuam tshuam rau cov feem uas tswj cov leeg, asterixis tuaj yeem tshwm sim. Hauv cov xwm txheej zoo li no, cov tsos mob feem ntau tsuas pom ntawm ib sab ntawm lub cev xwb. |
| Lwm yam mob nkeeg | Qhov mob no kuj tseem tuaj yeem tshwm sim los ntawm kev hloov pauv hauv cov tshuaj lom neeg hauv cov ntshav. Piv txwv li: cov ntshav qab zib qis (hypoglycemia), cov potassium qis (hypokalemia), cov magnesium qis (hypomagnesemia), lub plawv tsis ua haujlwm, thiab ua pa tsis ua haujlwm. Tsis tas li ntawd, muaj ib qho kab mob caj ces hu ua Wilson kab mob, uas ua rau tooj liab sib sau ua ke hauv lub cev, yog ib qho ua rau. |
Asterixis ua los ntawm cov tshuaj
Qee zaum, asterixis kuj tseem tuaj yeem tshwm sim ib ntus ua ib qho kev phiv ntawm qee yam tshuaj uas peb noj. Qhov kev pheej hmoo no tshwj xeeb tshaj yog rau cov neeg uas muaj teeb meem siab lossis raum.
Nov yog qee cov piv txwv:
- Cov tshuaj tiv thaiv qaug dab peg: tshwj xeeb tshaj yog phenytoin. Asterixis ua rau muaj qhov no kuj hu ua "phenytoin flap". Nws kuj tseem tuaj yeem ua rau muaj cov tshuaj xws li gabapentin, valproate, thiab carbamazepine.
- Cov tshuaj barbiturates
- Cov tshuaj Benzodiazepines
- Qee cov tshuaj tua kab mob
- Lithium (ib yam tshuaj siv rau kev sib npaug ntawm lub hlwb)
- Metoclopramide (tshuaj tiv thaiv ntuav)
Qhov no kho li cas?
Tsis muaj kev kho mob ncaj qha rau cov tsos mob ntawm asterixis. Cov kws kho mob sim nrhiav qhov ua rau thiab kho nws raws li qhov tsim nyog.
Piv txwv li:
- Yog tias qhov ua rau yog teeb meem siab, nws yuav raug kho.
- Yog tias qhov ua rau yog teeb meem raum, nws yuav raug kho.
- Yog tias qhov ua rau yog los ntawm cov tshuaj uas siv, tus kws kho mob yuav txiav txim siab seb puas yuav hloov cov tshuaj lossis txo qhov ntau npaum li cas.
Yog li ntawd, yog tias koj muaj asterixis, qhov tseem ceeb tshaj plaws yog nrhiav qhov ua rau thiab pib kho nws. Qhov no yeej tsis yog ib yam dab tsi uas koj tuaj yeem kho tau hauv tsev ntawm koj tus kheej.
Yog tias tsis kho, muaj tej yam txaus ntshai dab tsi?
Qhov kev pheej hmoo loj tshaj plaws ntawm kev tsis quav ntsej txog asterixis yog tias nws tuaj yeem ua rau muaj mob hnyav uas tuaj yeem ua rau tuag taus. Yog tias tsis kho, nws tuaj yeem ua rau lub hlwb puas tsuaj mus tas li, suav nrog kev xav tsis thoob, kev taug kev, thiab kev siv ceg.
Yog tias asterixis cuam tshuam rau ob txhais ceg lossis lub cev, nws tuaj yeem ua rau ntog tam sim ntawd, uas tuaj yeem ua rau raug mob hnyav.
Thaum twg koj yuav tsum nrhiav kev kho mob tam sim ntawd?
Yog tias koj muaj kev xav tias koj muaj cov tsos mob ntawm Asterixis, koj yuav tsum mus ntsib kws kho mob.
Txawm li cas los xij, yog tias koj muaj cov tsos mob hauv qab no, xav tias nws yog xwm txheej ceev kho mob :
- Yog tias muaj kev tsis meej pem hauv lub siab nrog rau cov tsos mob ntawm asterixis.
- Yog koj tsis paub qhov chaw, tsis paub lub sijhawm, lossis tsis paub koj tus kheej (disappearance ).
- Yog tias muaj kev hloov pauv ntawm lub hlwb .
Cov tsos mob no qhia tau tias lub hlwb ua haujlwm tau raug cuam tshuam loj heev. Yog li ntawd, thaum muaj xwm txheej zoo li no , nws yog ib qho tseem ceeb heev uas yuav tsum mus rau chav kho mob ceev (ETU) ntawm tsev kho mob tam sim ntawd.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Asterixis tsis yog ib yam kab mob. Nws yog ib qho cim ceeb toom ntawm ib qho mob hnyav uas yuav cuam tshuam rau lub siab, lub raum, lub plawv, lossis lub hlwb.
- Yog koj lossis ib tug neeg koj paub muaj cov tsos mob no ntawm tes co, tsis txhob tsis quav ntsej nws. Mus ntsib kws kho mob sai li sai tau.
- Yog tias cov tsos mob no nrog rau kev tsis meej pem, qaug zog, lossis tsis nco qab, nws yog qhov xwm txheej ceev. Mus rau Chav Kho Mob Ceev (ETU) tam sim ntawd.
- Tus mob no tsuas yog yuav tsum tau kuaj mob thiab kho los ntawm kws kho mob xwb. Tsis txhob sim kho lossis kuaj mob koj tus kheej.
👩🏽⚕️ Cov Lus Nug Ntxiv (FAQs)
💬 Cov tshuaj ntsiav Macitentan / Opsumit yog ib yam tshuaj tshwj xeeb uas muab rau tus kab mob twg?
Qhov no tsis yog ib yam tshuaj kho mob ib txwm muaj! Qhov no yog ib yam tshuaj zoo heev (Endothelin Receptor Antagonist) uas kho tau 'Pulmonary Arterial Hypertension (PAH),' ib yam kab mob uas ua rau cov hlab ntsha uas mus ntawm lub plawv mus rau lub ntsws nqaim/tawv, thiab cov ntshav siab hauv cov hlab ntsha ntawd siab heev ua rau nws tawg thiab tus neeg mob tuag. Nws 'Qeeb qeeb kev loj hlob ntawm tus kab mob' thiab ua rau lub neej ntev dua, tsis yog tsuas yog cov tsos mob xwb!
💬 Thaum koj tuag vim yog cov ntshav txhaws hauv koj lub ntsws, koj yuav ua li cas kom koj cov leeg ntshav nthuav dav / tswj tus kab mob los ntawm kev noj cov tshuaj no (Macitentan)?
Cov hlab ntsha hauv lub ntsws raug yuam kom cog thiab tawv (Fibrosis) los ntawm cov tshuaj lom neeg txaus ntshai hauv peb lub cev hu ua 'Endothelin-1'! Thaum cov tshuaj no nkag mus rau hauv cov ntshav, nws thaiv 100% ntawm lub sijhawm rau cov tshuaj ntawd khi rau cov receptors hauv cov hlab ntsha (ob qho tib si ETA thiab ETB receptors - Dual block). Tsis yog li ntawd xwb, cov tshuaj no kuj tseem tiv thaiv cov hlab ntsha kom tsis txhob tuab los ntawm kev nkag mus rau hauv cov hlwb hauv lub ntsws (Tissue penetration).
💬 Cov Lus Ceeb Toom Txog 'Black Box Warnings' uas cov poj niam/txiv neej uas noj cov tshuaj no (Opsumit) yuav tsum paub yog dab tsi?
Qhov txaus ntshai tshaj plaws yog qhov no raug txwv tsis pub rau 'cov niam cev xeeb tub'! Yog tias koj cev xeeb tub thaum haus qhov no, tus menyuam yuav raug deformed (Major Birth Defects) thiab tuag sab hauv (cov niam yuav tsum raug REMS program). Tsis tas li ntawd, qhov no yuav ua rau 'Cov phev tsawg dua / Tsis muaj menyuam' rau cov txiv neej! Tsis tas li ntawd, qee tus neeg cov hemoglobin (Anemia) tuaj yeem poob ntau thiab ua rau muaj anemia.
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