Koj puas muaj teeb meem ua pa xws li mob hawb pob? Thaum lub sijhawm zoo li no, tus kws kho mob yuav hais kom koj siv lub tshuaj nqus pa. Cov tshuaj Beta-agonists yog ib hom tshuaj tshwj xeeb uas muaj nyob hauv cov tshuaj nqus pa uas ua rau peb ua pa tau yooj yim dua. Txawm hais tias lub npe no nyuaj me ntsis, tab sis lawv lub luag haujlwm yooj yim heev. Cia peb tham txog qhov no kom meej me ntsis, yooj yim heev.
Hauv lwm lo lus, beta-agonist yog dab tsi?
Xav txog cov cell hauv peb lub cev zoo li muaj cov 'switches' lossis 'buttons' me me. Hauv kev kho mob, peb hu cov receptors no. Hom tshuaj no, hu ua beta-agonist, tig cov 'switches' no hu ua beta-receptors hauv peb lub ntsws thiab lwm yam kabmob.
Thaum lub qhov hloov no raug qhib, cov leeg nqaij nyob ib puag ncig cov hlab pa hauv lub ntsws yuav so. Qhov no qhib cov hlab pa nqaim thiab ua rau peb ua pa tau yooj yim dua. Yog vim li cas cov tshuaj no thiaj hu ua 'bronchodilators'. Tsis tas li ntawd xwb, lawv pab ua kom lub plawv dhia ceev thiab ua kom lub plawv ua haujlwm tau zoo dua qee yam.
Puas muaj cov hom beta-agonists tseem ceeb?
Yog lawm, cov tshuaj no kuj muab faib ua peb pawg tseem ceeb, nyob ntawm seb muaj hom beta-receptors hauv peb lub cev.
- Cov tshuaj Beta-1 agonists: Cov no feem ntau cuam tshuam rau cov receptors hauv peb lub plawv . Hom tshuaj no ua rau lub plawv dhia ceev dua thiab pab nws nqus ntshav nrog lub zog ntau dua. Yog vim li ntawd cov kws kho mob siv lawv rau qee yam mob plawv thiab xwm txheej ceev.
- Cov tshuaj Beta-2 agonists: Qhov no yog hom tshuaj uas siv ntau tshaj plaws. Cov tshuaj no, tshwj xeeb tshaj yog cov uas muab los ntawm lub tshuab ua pa, ua haujlwm los ntawm kev khi ncaj qha rau cov receptors hauv lub ntsws , ua rau cov leeg hauv txoj hlab pa so thiab ua rau nws yooj yim dua rau kev ua pa. Lawv yog qhov tseem ceeb hauv kev kho mob ntawm cov mob xws li mob hawb pob thiab COPD (Chronic Obstructive Pulmonary Disease).
- Cov tshuaj Beta-3 agonists: Cov no yog cov tshuaj tshiab. Cov tshuaj tam sim no hauv pawg no feem ntau ua haujlwm los ntawm kev so cov leeg hauv lub zais zis , txo qhov xav tau tso zis ntau zaus. Qhov no txhais tau tias lawv siv los kho tus mob hu ua lub zais zis ua haujlwm ntau dhau.
Kuj tseem muaj cov hom beta-2 agonists.
Yog lawm, hom beta-2 no uas tau muab rau kev ua pa nyuaj kuj muab faib ua ob ntu. Nws yog ib qho tseem ceeb heev rau koj kom paub qhov no.
| Hom tshuaj | Kev piav qhia |
|---|---|
| Cov Beta-Agonists Ua Haujlwm Luv (SABA) | Cov no hu ua "cov tshuaj nqus pa cawm siav." Lawv siv thaum mob hawb pob zuj zus tuaj lossis thaum koj ua pa nyuaj. Lawv ua haujlwm hauv ob peb feeb xwb thiab pab kom koj zoo sai. |
| Cov Beta-Agonists Ua Haujlwm Ntev (LABA) | Cov no tsis yog siv rau kev pab sai sai. Lawv siv txhua hnub, rau lub sijhawm tsis tu ncua, los tswj cov tsos mob thiab tiv thaiv kev ua pa nyuaj. Lawv cov txiaj ntsig kav ntev li ob peb teev. Feem ntau lawv muab ua ke nrog cov tshuaj steroid (corticosteroid). |
Cov tshuaj no ua haujlwm li cas hauv lub cev?
Txoj kev zoo tshaj plaws los nkag siab qhov no yog xav txog peb lub cev txoj kev teb "sib ntaus los yog khiav". Xav txog koj tab tom yuav ntsib teeb meem tam sim ntawd. Lub sijhawm ntawd, koj lub cev npaj yuav sib ntaus los yog khiav.
Lub sijhawm no, cov cim qhia los ntawm lub hlwb, ua rau cov hlab pa hauv lub ntsws dav dua kom tau txais cov pa oxygen ntau dua, thiab ua kom lub plawv dhia ceev dua kom xa cov ntshav uas muaj oxygen mus rau cov leeg nqaij sai dua.
Qhov ntawd yog qhov uas cov tshuaj beta-agonist ua tsis raws li txoj cai. Lawv qhib cov 'switches' (receptors) thiab ua rau lub cev teb zoo li nws tab tom ntsib xwm txheej ceev. Yog vim li ntawd cov leeg nqaij hauv lub ntsws thiaj li so, ua rau nws yooj yim dua rau kev ua pa.
Cov tshuaj beta-agonist uas siv ntau tshaj plaws yog dab tsi?
Muaj ntau hom tshuaj beta-agonist uas cov kws kho mob sau ntawv kom siv. Nov yog qee cov piv txwv:
| Pawg tshuaj | Piv txwv (cov npe tshuaj) |
|---|---|
| Beta-2 ua haujlwm luv luv (SABA) | Salbutamol / Albuterol, Levalbuterol |
| Beta-2 ua haujlwm ntev (LABA) | Formoterol, Salmeterol, Indacaterol |
| Beta-1 agonist | Dobutamine, Norepinephrine |
| Beta-3 agonists | Mirabegron |
Puas muaj tej yam tshwm sim tsis zoo rau cov tshuaj no?
Ib yam li lwm yam tshuaj, cov beta-agonists tuaj yeem ua rau muaj kev phiv rau qee tus neeg. Txawm li cas los xij, thaum siv ua lub tshuaj nqus pa, cov tshuaj mus ncaj qha rau hauv lub ntsws, yog li cov kev phiv feem ntau tsis hnyav heev. Txawm li cas los xij, qee tus neeg yuav muaj:
- Lub plawv dhia ceev ceev (Tachycardia)
- Lub plawv dhia tsis xwm yeem (Arrhythmia)
- Kev tshee hnyo
- Kev ntxhov siab
- Mob taub hau
- Mob nqaij ntshiv
- Tawm hws
Qhov tseem ceeb tshaj plaws yog tias yog koj muaj tej yam tshwm sim no, lossis yog koj xav tias muaj dab tsi txawv txawv tom qab siv tshuaj, nrog koj tus kws kho mob tham tam sim ntawd. Nws yuav hloov tau qhov ntau npaum li cas lossis sau lwm yam tshuaj rau koj.
Thaum twg koj yuav tsum mus ntsib kws kho mob?
Muaj ntau qhov xwm txheej uas nws yog ib qho tseem ceeb heev uas yuav tsum mus ntsib koj tus kws kho mob.
- Yog tias koj ntsib cov kev mob tshwm sim tsis zoo, tsis tau xav txog .
- Yog koj xav tias koj cov tshuaj tsis ua haujlwm zoo li yav tas los (piv txwv li, koj yuav tsum siv koj lub tshuaj nqus pa ntau dua li yav dhau los kom tau kev pab).
- Yog koj xav tias koj cov tsos mob zuj zus tuaj thiab koj tswj tsis tau lawv .
Hauv qhov no, koj tus kws kho mob tuaj yeem tshuaj xyuas koj txoj kev npaj kho mob thiab muab qhov kev daws teeb meem zoo tshaj plaws thiab yooj yim rau koj.Tsis txhob tsum noj koj cov tshuaj lossis hloov qhov ntau npaum li cas yam tsis tau kev qhia los ntawm kws kho mob. Yog tias koj muaj tej yam kev mob tshwm sim hnyav, mus rau chav kho mob ceev (ETU) ze tshaj plaws tam sim ntawd.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov tshuaj Beta-agonists yog ib hom tshuaj uas ua rau ua pa yooj yim dua, feem ntau yog siv rau cov kab mob ua pa xws li mob hawb pob thiab COPD.
- Muaj ob hom tseem ceeb: tshuaj ua haujlwm luv luv (SABA) uas pab kho sai sai thaum muaj xwm txheej ceev, thiab tshuaj ua haujlwm ntev (LABA) uas tswj tau tus kab mob mus sij hawm ntev.
- Siv cov tshuaj no raws nraim li koj tus kws kho mob tau hais, thiab tsuas yog siv raws li qhov ntau npaum li tau teev tseg xwb .
- Yuav tsum paub txog tej yam tshwm sim tsis zoo xws li lub plawv dhia ceev thiab tes tshee hnyo. Yog tias koj muaj teeb meem dab tsi, qhia rau koj tus kws kho mob tam sim ntawd.
- Yog koj xav tias koj txoj kev kho mob tsis ua haujlwm zoo lossis koj cov tsos mob hnyav zuj zus, tsis txhob kho koj tus kheej thiab nrhiav kev pab kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus