Koj puas muaj mob hawb pob? Tej zaum koj siv koj lub tshuaj nqus pa raws li tau sau tseg thiab noj lwm yam tshuaj, tab sis koj cov tsos mob ntawm mob hawb pob tsis zoo dua. Yog tias koj hnov lub suab nrov nrov, lub hauv siab nruj, thiab hnoos, koj yuav muaj mob hawb pob nruab nrab mus rau hnyav. Txoj kev kho mob tshiab no, hu ua 'Biologic Therapy', yog siv rau cov mob hawb pob uas nyuaj tswj.
Hais yooj yim xwb, Biologic Therapy yog dab tsi?
Qhov no yog kev kho mob niaj hnub, tsom mus rau tus neeg mob hawb pob hnyav. Txawm hais tias cov tshuaj nqus pa ib txwm ua rau txoj hlab pa dav dua ib ntus thiab ua rau ua pa yooj yim dua, kev kho mob biologic mus tob dua.
Xav txog seb, qhov laj thawj tseem ceeb uas ua rau peb mob hawb pob yog o ntawm txoj hlab pa uas tshwm sim los ntawm lwm yam kev ua haujlwm ntawm lub cev tiv thaiv kab mob. Yog li cov tshuaj biologic no ua yog tsom mus rau cov tshuaj tiv thaiv kab mob, cov hlwb lossis cov molecules hauv lub cev uas ua rau mob hawb pob thiab nres lawv txoj haujlwm. Vim li no, mob hawb pob raug tswj hwm ntawm qib yooj yim.
Kev kho mob no muaj ob txoj kev tseem ceeb. Ib txoj yog txhaj tshuaj rau hauv qab daim tawv nqaij (subcutaneous injection) thiab lwm txoj yog txhaj tshuaj rau hauv cov hlab ntsha (IV infusion).
Qhov tseem ceeb yog tias qhov no tsis yog kev kho mob uas sawv ntawm koj tus kheej xwb. Nws yuav tsum siv nrog koj cov tshuaj nqus pa uas twb muaj lawm thiab lwm yam tshuaj kho mob hawb pob.
Txoj kev kho mob no haum rau leej twg?
Kev kho mob siv tshuaj kho mob tsis yog kev kho mob rau txhua tus neeg mob hawb pob. Koj tus kws kho mob yuav xav txog ntau yam ua ntej pom zoo kom siv txoj kev kho mob no rau koj. Lub rooj hauv qab no yuav muab lub tswv yim zoo rau koj.
| Cov xwm txheej uas koj yuav raug xa mus rau Biologic Therapy | |
|---|---|
| Tsis raug tswj los ntawm cov tshuaj uas tau sau tseg | Yog tias koj cov tsos mob ntawm tus mob hawb pob tsis raug tswj txawm tias koj siv koj lub tshuaj nqus pa thiab lwm yam tshuaj kom raug. |
| Cov txiaj ntsig ntawm kev kuaj ntshav | Yog tias koj muaj cov Eosinophils (cov qe ntshav dawb uas ua rau mob hauv lub ntsws) lossis IgE (cov tshuaj tiv thaiv kab mob ntsig txog kev ua xua) ntau ntxiv hauv koj cov ntshav. |
| Cov ua rau mob hnyav dua | Yog koj paub tias dab tsi ua rau koj mob hawb pob thiab zam lawv, tab sis koj cov tsos mob tseem muaj. |
| Cov tsos mob tshwm sim ntau zaus | Yog tias koj sawv thaum ib tag hmo nrog hnoos, lossis yog tias koj siv koj lub tshuaj pab ua pa ntau tshaj ob zaug hauv ib lub lim tiam. |
| Kev mob hnyav zuj zus | Yog tias koj yuav tsum tau noj cov tshuaj corticosteroid ntau tshaj ob zaug hauv ib xyoos lossis yuav tsum mus rau ETU (Emergency Treatment Unit). |
| Kev pw hauv tsev kho mob | Yog koj yuav tsum tau nyob hauv tsev kho mob thiab tau txais kev kho mob vim yog mob hawb pob. |
Muaj cov tshuaj biologic hom twg rau kev mob hawb pob?
Muaj ntau hom tshuaj kho mob uas tau pom zoo txog tam sim no. Txhua hom tshuaj ua haujlwm txawv me ntsis. Koj tus kws kho mob yuav xaiv cov tshuaj uas haum rau koj tshaj plaws raws li koj hom mob hawb pob thiab cov txiaj ntsig ntawm kev kuaj ntshav.
| Lub npe ntawm cov tshuaj | Kev ua haujlwm thiab txoj kev xa khoom | Cov kev mob tshwm sim feem ntau |
|---|---|---|
| Omalizumab (Xolair®) | Kho mob hawb pob uas ua rau muaj kev ua xua. Nws raug txhaj rau hauv qab daim tawv nqaij txhua 2-4 lub lis piam. | Mob nqaij, mob pob qij txha, qaug zog heev, o/mob ntawm qhov chaw txhaj tshuaj. |
| Mepolizumab (Nucala®) | Kho cov mob hawb pob uas muaj cov kab mob eosinophilic. Yuav txhaj tshuaj rau hauv qab daim tawv nqaij txhua 4 lub lis piam. | Mob taub hau, mob nraub qaum, tsis muaj zog, qaug zog, o/mob ntawm qhov chaw txhaj tshuaj. |
| Reslizumab (Cinqair®) | Kho mob hawb pob eosinophilic. Muab tshuaj rau hauv cov hlab ntsha (IV) txhua 4 lub lis piam. | Mob caj pas, mob nqaij. |
| Benralizumab (Fasenra®) | Kho mob hawb pob eosinophilic. 3 koob tshuaj thawj zaug yog muab txhua 4 lub lis piam, tom qab ntawd txhua 8 lub lis piam. | Mob taub hau, mob caj pas. |
| Dupilumab (Dupixent®) | Kho cov mob eosinophilic hawb pob thiab lwm yam mob uas tshwm sim los ntawm kev o. Txhaj tshuaj txhua 2 lub lis piam. | Mob caj pas, o/mob ntawm qhov chaw txhaj tshuaj, cov qe ntshav dawb ntau ntxiv. |
| Tezepelumab (Tezspire®) | Ib yam tshuaj tshiab rau kev mob hawb pob hnyav. Nws txo qhov o. Nws raug txhaj txhua 4 lub lis piam. | Mob caj pas, mob nraub qaum, mob pob qij txha. |
Kev kho mob no yuav siv sijhawm ntev npaum li cas?
Qhov no feem ntau yog kev kho mob mus sij hawm ntev. Nws yuav siv sijhawm tsawg kawg 4-6 lub hlis kom paub tseeb tias cov tshuaj no puas ua haujlwm rau koj. Yog li nws yog ib qho tseem ceeb uas yuav tsum ua siab ntev nrog koj txoj kev kho mob.
Kuv puas yuav tsum tau siv kuv lub tshuaj nqus pa txuas ntxiv mus?
Yog, yeej yog li ntawd.Qhov no yog qhov tseem ceeb tshaj plaws. Txawm tias tom qab pib kho mob biologic, tsis txhob tsum noj koj cov tshuaj inhalers thiab lwm yam tshuaj uas koj tus kws kho mob tau sau tseg. Raws li lub sijhawm dhau mus, yog tias koj tus mob hawb pob tswj tau zoo, koj tus kws kho mob yuav txiav txim siab txo koj cov tshuaj inhalers. Tab sis qhov no tsuas yog yuav tsum ua raws li kev qhia ntawm kws kho mob xwb.
Cov txiaj ntsig thiab kev pheej hmoo ntawm kev kho mob no yog dab tsi?
Ib yam li kev kho mob twg los xij, qhov no muaj cov txiaj ntsig zoo thiab cov kev pheej hmoo me.
Cov txiaj ntsig tseem ceeb:
- Nws txo qhov o ntawm txoj hlab pa thiab tswj tau cov tsos mob ntawm tus mob hawb pob zoo.
- Mob khaub thuas thiab hnoos ntau zaus yuav txo qis.
- Koj yuav muaj peev xwm tawm dag zog thiab ua tiav cov haujlwm txhua hnub yam tsis tas yuav ua haujlwm hnyav li yav dhau los.
- Tus naj npawb ntawm cov sijhawm koj sawv thaum hmo ntuj txo qis.
- Qhov xav tau mus rau ETU (Chav Kho Mob Thaum Muaj Xwm Ceev) tsawg zaus yuav txo qis.
- Lub neej zoo dua qub lawm.
Tej yam txaus ntshai uas yuav tshwm sim:
- Kev ua xua hnyav heev: Tsis tshua muaj neeg yuav muaj kev ua xua hnyav heev (anaphylaxis). Qhov no yog vim li cas ob peb koob tshuaj thawj zaug thiaj li muab rau hauv tsev kho mob lossis chaw kho mob uas muaj kev saib xyuas los ntawm kws kho mob.
- Kev Pheej Hmoo ntawm kev kis kab mob parasitic: Cov tshuaj uas txo cov eosinophils yuav txo qhov muaj peev xwm ntawm lub cev los tawm tsam cov kab mob parasitic, tshwj xeeb tshaj yog helminths. Yog li koj tus kws kho mob yuav xav txog qhov ntawd ua ntej pib kho mob no.
Tseem Ceeb: Tsis txhob tsum noj cov tshuaj no tam sim ntawd rau txhua qhov laj thawj yam tsis tau koj tus kws kho mob qhia. Ua li ntawd yuav ua rau koj cov tsos mob ntawm tus mob hawb pob hnyav zuj zus.
Thaum twg yuav tsum nrog koj tus kws kho mob tham
Hauv cov xwm txheej hauv qab no, nco ntsoov sab laj nrog koj tus kws kho mob thiab qhia rau nws paub.
- Yog tias cov tsos mob ntawm tus mob hawb pob tsis zoo dua lossis hnyav zuj zus tom qab kho mob ob peb lub hlis.
- Yog tias muaj cov tsos mob tshiab ntawm kev ua xua (piv txwv li, tawv nqaij tawm pob, khaus).
- Yog koj muaj lus nug lossis kev txhawj xeeb txog kev kho mob.
Kev kho mob no koj yuav tau txais los ntawm kev pom zoo ntawm tus kws kho mob tshwj xeeb, los ntawm chav kho mob tshwj xeeb hauv tsev kho mob (chaw txhaj tshuaj) lossis los ntawm lub tsev kho mob tshwj xeeb. Kev kho mob no yuav kim me ntsis. Tab sis koj tuaj yeem tham nrog koj tus kws kho mob txog nws thiab nrhiav cov ntaub ntawv ntxiv.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Kev Kho Mob Biologic yog ib txoj kev kho mob siab heev uas siv rau cov mob hawb pob hnyav uas nyuaj rau tswj nrog cov tshuaj ib txwm muaj.
- Qhov no tsis yog kev kho mob hawb pob, tab sis nws pab tswj tus kab mob tau zoo heev.
- Thaum koj tau txais kev kho mob no, nws yog ib qho tseem ceeb uas yuav tsum txuas ntxiv siv koj lub tshuaj nqus pa thiab lwm yam tshuaj uas koj tus kws kho mob tau sau tseg.
- Seb qhov kev kho mob no puas haum rau koj lossis tsis haum yuav txiav txim siab tom qab xav txog koj cov tsos mob thiab cov ntawv kuaj ntshav tshwj xeeb.
- Vim tias nws yuav siv sijhawm ntau lub hlis kom pom cov txiaj ntsig ntawm kev kho mob, nws yog ib qho tseem ceeb heev uas yuav tsum ua siab ntev thiab ua raws li cov lus qhia ntawm kws kho mob thaum lub sijhawm kho mob.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus