Thaum koj saib daim ntawv qhia txog cov ntshav, koj puas tau pom ib qho nqi hu ua 'Calcium'? Peb txhua tus paub tias calcium zoo npaum li cas rau cov pob txha thiab cov hniav. Tab sis qee zaum koj tus kws kho mob yuav hais kom kuaj tshwj xeeb hu ua "Ionized Calcium" es tsis yog kuaj calcium ib txwm. Tom qab ntawd peb xav tias, "Qhov ntawd yog dab tsi? Puas yog tib yam calcium?" Muaj qhov sib txawv me me, tab sis tseem ceeb heev ntawm ob qho no. Hnub no, cia peb tham txog tus phab ej tseem ceeb heev hauv peb lub cev hu ua "ionized calcium".
Calcium Ionized yog dab tsi?
Hais yooj yim xwb, qhov no yog cov calcium uas "dawb" lossis "ua haujlwm" hauv peb cov ntshav. Xav txog nws, 99% ntawm tag nrho cov calcium hauv peb lub cev yog nyob rau hauv peb cov pob txha thiab cov hniav. Nws zoo li cov nyiaj hauv lub tsev txhab nyiaj. Cov seem 1% ncig hauv cov ntshav.
Tam sim no, ntawm 1% ntawm cov calcium no hauv cov ntshav, qee qhov ntawm nws khi rau cov protein (tshwj xeeb tshaj yog albumin), lossis "alloyed." Peb hu qhov no ua "bound calcium." Qhov no tsis ua haujlwm, zoo li ib tug neeg zaum ntawm lub rooj zaum ntawm qhov chaw nres tsheb npav. Nws tsuas yog nyob ntawd, tsis ua dab tsi.
Qhov seem ntawd yog qhov uas ncig mus los hauv cov ntshav "dawb" yam tsis muaj kev khi rau cov protein twg. Qhov seem dawb no, uas nquag ua haujlwm yog qhov peb hu ua ionized calcium lossis "free calcium." Nws yog cov calcium dawb no uas ua haujlwm hauv lub cev, pab txhawb rau cov yam tseem ceeb tshaj plaws. Qhov seem no muaj li ntawm 50% ntawm tag nrho cov calcium.
Qhov ntawd txhais tau tias, nws yog cov calcium ionized no uas ua cov haujlwm tseem ceeb hauv peb lub cev, xws li xa cov lus ntawm cov hlab ntsha, cov leeg nqaij qaug zog, thiab ua rau lub plawv dhia.
Vim li cas cov calcium ionized thiaj li tseem ceeb rau peb lub cev?
Txawm hais tias cov calcium dawb me me xwb los, nws txoj haujlwm tsis yog qhov tsis tseem ceeb. Nws yog qhov tseem ceeb rau kev ua haujlwm zoo ntawm ntau lub cev tseem ceeb hauv peb lub cev.
- Cov hlab ntsha: Cov hlab ntsha nqa cov lus los ntawm peb lub hlwb mus rau lwm qhov ntawm lub cev. Ib yam li hluav taws xob khiav raws ib txoj hlua. Cov calcium uas muaj ionized yog qhov tseem ceeb rau cov lus no kom khiav tau zoo.
- Cov leeg nqaij: Peb siv peb cov leeg nqaij los txav peb txhais tes thiab ob txhais ceg, taug kev, thiab tsa khoom. Tag nrho cov leeg nqaij no xav tau cov calcium dawb no los cog thiab so. Lub plawv kuj yog ib cov leeg nqaij tshwj xeeb. Qhov no tseem ceeb heev rau nws kom dhia nrawm.
- Lub Plawv: Qhov no pab tswj lub plawv dhia thiab lub suab kom zoo.
- Kev ua kom cov ntshav txhaws:Thaum peb muaj qhov txhab qhov twg thiab los ntshav, ib qho txheej txheem nyuaj tshwm sim los tiv thaiv kev los ntshav. Ib kauj ruam tseem ceeb heev hauv cov txheej txheem ntawd yog cov calcium ionized no.
Vim li cas koj thiaj thov qhov no es tsis txhob kuaj calcium li niaj zaus?
Nov yog ib lo lus nug zoo heev. Kev kuaj calcium feem ntau ntsuas tag nrho cov calcium hauv cov ntshav. Uas yog, qhov sib npaug ntawm ob qho tib si "khi" thiab "dawb".
Txawm li cas los xij, muaj qee kis uas tus neeg cov protein hauv cov ntshav (albumin) qis. Piv txwv li, ib tus neeg uas mob hnyav heev, ib tus neeg uas muaj kab mob raum, lossis ib tus neeg uas muaj kab mob siab yuav muaj cov protein qis. Tom qab ntawd, cov calcium uas khi rau cov protein kuj txo qis. Yog li ntawd, yog tias koj saib lawv cov "Tag Nrho Calcium", nws yuav qhia tau tias tus nqi qis.
Tiamsis qhov ntau ntawm cov calcium "dawb" (ionized calcium) uas ua haujlwm hauv nws lub cev tej zaum yuav yog qhov ib txwm muaj. Tom qab ntawd, yog tias koj txiav txim siab raws li daim ntawv qhia txog calcium tag nrho xwb, nws yuav tsis raug. Hauv cov xwm txheej zoo li no, cov kws kho mob thov kom kuaj calcium ionized kom paub qhov tseeb ntawm cov calcium uas ua haujlwm hauv lub cev.
Nov yog qee qhov xwm txheej tseem ceeb uas tus kws kho mob yuav thov kom kuaj qhov no:
- Yog tias cov protein (tshwj xeeb tshaj yog albumin) hauv cov ntshav tsis zoo li qub.
- Rau ib tug neeg uas mob hnyav heev thiab tab tom txais cov tshuaj saline (IV fluids).
- Rau ib tug neeg uas npaj rau kev phais loj.
- Rau ib tus neeg uas feem ntau tau txais kev hloov ntshav.
- Saib xyuas cov niam cev xeeb tub thiab cov menyuam mos uas yug tshiab.
- Thaum muaj kev xav tias muaj mob pancreatitis.
- Yog tias muaj kev xav tias muaj kab mob ntawm cov qog parathyroid.
Yuav npaj li cas rau qhov kev xeem?
Feem ntau koj yuav tsum yoo mov li 6 teev ua ntej qhov kev kuaj mob. Haus dej me ntsis los tau. Nws tseem ceeb heev uas yuav tsum qhia rau koj tus kws kho mob txog txhua yam tshuaj, cov vitamins, thiab cov tshuaj ntxiv uas koj noj. Qee cov tshuaj tuaj yeem cuam tshuam rau cov txiaj ntsig ntawm qhov kev kuaj mob no, yog li koj tus kws kho mob yuav hais kom koj tsum tsis txhob noj lawv ib hnub ua ntej qhov kev kuaj mob. Tab sis nco ntsoov, tsis txhob tsum tsis txhob noj tshuaj yam tsis tau koj tus kws kho mob qhia.
Cov calcium ionized uas ib txwm muaj yog dab tsi?
Cov nqi no yuav txawv me ntsis nyob ntawm lub chaw kuaj mob uas ua qhov kev xeem. Ib txwm muab koj tus nqi piv rau "Normal Range" ntawm koj daim ntawv qhia.
| Pawg hnub nyoog | Qhov ntau npaum li cas (mg/dL) | Qhov ntau npaum li cas (mmol/L) |
|---|---|---|
| Cov menyuam mos tshiab | 4.8 – 5.3 mg/dL | 1.20 – 1.32 mmol/L |
| Cov menyuam yaus | 4.8 – 5.5 mg/dL | 1.20 – 1.38 mmol/L |
| Cov neeg laus | 4.6 – 5.3 mg/dL | 1.15 – 1.32 mmol/L |
Yog tias cov calcium ionized txo qis (Hypocalcemia)
Kev txo qis ntawm cov calcium uas ua haujlwm tau hauv cov ntshav (hu ua hypocalcemia) tuaj yeem tshwm sim los ntawm ntau yam mob.
- Hypoparathyroidism: Ib qho mob uas cov qog parathyroid hauv caj dab tsis tsim cov tshuaj hormones (PTH) txaus uas tswj cov calcium hauv lub cev.
- Pancreatitis: o ntawm lub pancreas.
- Tsis txaus Vitamin D: Vitamin D yog qhov tseem ceeb rau lub cev kom nqus tau calcium los ntawm cov khoom noj.
- Kev ua haujlwm tsis zoo ntawm lub raum.
- Malabsorption ntawm cov khoom noj.
- Kab mob Rickets rau menyuam yaus.
Cov tsos mob ntawm kev poob qis
Thaum cov calcium txo qis, ntau yam tsos mob tuaj yeem tshwm sim.
| Hom cwj pwm | Cov tsos mob qhia tau |
|---|---|
| Cov leeg thiab cov hlab ntsha cuam tshuam nrog | Cov leeg nqaij mob, loog ntawm ob txhais ceg thiab ib ncig ntawm lub qhov ncauj, tingling. |
| Kev cuam tshuam txog lub hlwb thiab lub hlwb | Kev tsis nco qab, kev tsis meej pem, kev nyuaj siab. |
| Lwm yam nta | Cov rau tes tsis muaj zog thiab yooj yim tawg, daim tawv nqaij qhuav. |
Yog tias nws txo qis, koj yuav ua li cas?
Koj tus kws kho mob yuav xub txiav txim seb yog vim li cas koj cov calcium tsis txaus. Tom qab ntawd, thaum kho qhov teeb meem ntawd, lawv yuav pib kho kom koj cov calcium rov qab zoo li qub.
- Cov tshuaj calcium ntxiv
- Cov tshuaj Vitamin D ntxiv
- Qee zaum cov tshuaj calcium gluconate txhaj rau hauv cov hlab ntsha
- Kev hloov pauv ntawm cov tshuaj hormones parathyroid (PTH)
Qhov tseem ceeb tshaj plaws yog koj tus kws kho mob yuav txiav txim siab txog qhov kev kho mob no. Nws yuav qhia koj tias yam twg zoo tshaj plaws rau koj thiab koj yuav tsum noj ntev npaum li cas. Tsis txhob mus rau lub tsev muag tshuaj thiab yuav cov tshuaj calcium raws li koj lub siab nyiam.
Yog tias cov calcium ionized nce ntxiv (Hypercalcemia)
Kev nce ntxiv ntawm cov calcium uas nquag ua haujlwm hauv cov ntshav (hu ua hypercalcemia) kuj yog ib qho mob uas yuav tsum tau saib xyuas.
- Hyperparathyroidism: Kev tsim cov tshuaj hormones ntau dhau los ntawm cov qog parathyroid.
- Hyperthyroidism: Cov thyroid caj pas ua haujlwm ntau dhau.
- Qee cov mob qog noj ntshav: Piv txwv li, ntau yam mob myeloma, uas yog mob qog ntshav hauv cov ntshav.
- Kab mob Paget ntawm pob txha.
- Kev noj ntau dhau ntawm cov vitamin D hauv lub cev.
Cov tsos mob ntawm kev nce ntxiv
Txawm tias thaum cov calcium ntau ntxiv, ntau cov tsos mob tuaj yeem tshwm sim.
| Hom cwj pwm | Cov tsos mob qhia tau |
|---|---|
| Cov yam ntxwv dav dav ntawm lub cev | qaug zog heev, mob taub hau, xeev siab thiab ntuav, tsis xav noj mov. |
| Kev zom zaub mov | Cem quav, mob plab. |
| Txog raum | Tso zis ntau zaus, nqhis dej ntau dhau. |
| Cov pob txha thiab cov leeg nqaij | Mob pob txha, mob nqaij lossis qaug zog. |
| Kev puas siab puas ntsws | Kev nco tsis zoo, kev nyuaj siab. |
Yuav ua li cas yog tias nws nce ntxiv?
Thaum kho cov calcium uas ntau dhau, nws yog ib qho tseem ceeb uas yuav tsum xub txheeb xyuas qhov ua rau. Cov kev kho mob sib txawv nyob ntawm qhov ua rau.
- Cov tshuaj uas tswj kev ua haujlwm ntawm cov qog parathyroid (Calcimimetics).
- Cov tshuaj uas ua rau cov pob txha muaj zog thiab txo cov calcium hauv cov ntshav (Bisphosphonates).
- Yog tias qhov mob no yog tshwm sim los ntawm cov vitamin D ntau, cov tshuaj xws li prednisone yuav raug sau tseg.
- Yog tias qhov mob hnyav heev, yuav tsum tau mus pw hauv tsev kho mob thiab muab cov kua ntsev (IV fluids) rau hauv cov hlab ntsha.
- Yog tias nws yog vim muaj qee yam zoo li qog nqaij hlav ntawm cov qog parathyroid, nws tuaj yeem raug phais tshem tawm (parathyroidectomy).
Kev kho mob no kuj tseem txiav txim siab los ntawm kev nrhiav qhov ua rau muaj calcium ntau ntxiv. Tsis txhob ua dab tsi yam tsis tau koj tus kws kho mob qhia. Qee zaum qhov no tuaj yeem yog xwm txheej ceev hauv kev kho mob.
Cov Lus Qhia Txog Kev Coj Mus Tsev
- Cov Calcium uas muaj ionized yog cov calcium uas "dawb" thiab "ua haujlwm" hauv peb cov ntshav. Nws yog qhov tseem ceeb rau ntau yam haujlwm tseem ceeb hauv peb lub cev.
- Txawm hais tias kev kuaj calcium tsis tu ncua qhia txog tag nrho cov calcium, kev kuaj calcium ionized muab cov duab meej dua ntawm cov calcium uas ua haujlwm hauv lub cev.
- Qhov kev kuaj no tseem ceeb heev rau cov mob hnyav, kab mob raum, thiab ua ntej phais.
- Qhov calcium qis lossis siab no yuav yog ib qho tsos mob ntawm ib qho mob uas twb muaj lawm.
- Nco ntsoov tham txog koj cov txiaj ntsig kuaj thiab txhua yam kev kho mob nrog koj tus kws kho mob. Tsis txhob noj tshuaj rau koj tus kheej lossis tsum tsis txhob noj tshuaj.
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Tsis muaj lus teb tau muab tso tawm. Ntxiv koj cov lus tawm ntawm no thawj zaug.
Ntxiv koj cov lus