Koj puas muaj qhov teeb meem 'ntsiag to' no hauv koj cov ntshav? Cia peb kawm txog Smoldering Multiple Myeloma (SMM)!

Qee zaum, tej teeb meem loj tuaj yeem tshwm sim hauv peb lub cev yam tsis muaj tsos mob sab nraud. Tej zaum koj yuav xav tias, "Auj, qhov ntawd yuav tshwm sim li cas?" Zoo, yog, nws tuaj yeem tshwm sim. Hnub no peb yuav tham txog ib qho mob tshwj xeeb uas tuaj yeem tshwm sim ntsiag to, yam tsis muaj tsos mob, tab sis muaj peev xwm hloov mus ua mob qog noj ntshav loj heev yav tom ntej. Cov kws kho mob hu qhov no (Smoldering Multiple Myeloma - SMM) . Hais yooj yim, qhov no zoo li theem pib ntawm tus kab mob hu ua "chronic multiple myeloma."

Mob Smoldering Multiple Myeloma (SMM) yog dab tsi?

Hais yooj yim xwb, Smoldering Multiple Myeloma yog ib yam mob uas cuam tshuam rau koj cov ntshav thiab pob txha. Qhov no tuaj yeem hloov mus ua mob qog ntshav tsawg tsawg hu ua active Multiple Myeloma (MM) . Tam sim no koj yuav xav paub tias, "Qhov multiple myeloma no yog dab tsi?" Cov qe ntshav dawb yog ib hom qe ntshav dawb hauv peb lub cev tiv thaiv kab mob. Cov no yog cov uas tsim cov tshuaj tiv thaiv kab mob uas pab peb lub cev tawm tsam kab mob. Txawm li cas los xij, qee zaum cov qe ntshav dawb no tuaj yeem hloov pauv thiab dhau los ua cov qe ntshav tsis zoo. Thaum ntawd yog thaum muaj mob hu ua multiple myeloma tshwm sim.

Yog li, SMM yog theem "ntsiag to" ua ntej nws dhau los ua mob qog noj ntshav hu ua multiple myeloma, tsis muaj tsos mob dab tsi. Qee zaum nws yuav siv sijhawm ntau xyoo rau SMM kom dhau los ua mob qog noj ntshav multiple myeloma. Qhov xav tsis thoob yog tias qee tus neeg uas muaj SMM yeej tsis tau mob qog noj ntshav multiple myeloma. Yog vim li ntawd cov kws kho mob thiaj li kuaj xyuas cov neeg uas muaj SMM kom paub seb nws puas tuaj yeem hloov mus ua mob qog noj ntshav uas tab tom ua.

Puas yog (SMM) mob qog noj ntshav?

Qhov no yog ib lo lus nug nyuaj me ntsis. SMM tsis raug kho raws li mob qog noj ntshav. Txawm li cas los xij, vim tias nws tuaj yeem hloov mus ua mob qog noj ntshav hu ua active multiple myeloma, nws suav hais tias yog qhov ua ntej ntawm mob qog noj ntshav. Xav txog koj muaj ib qho chaw txawv txawv ntawm koj daim tawv nqaij, ib lub cim yug. Qhov ntawd yuav yog ib qho cim qhia ntxov ntawm mob qog noj ntshav ntawm daim tawv nqaij, puas yog? Qhov ntawd yog qhov SMM yog. Nws txhais tau tias koj muaj qee qhov muaj feem yuav mob qog noj ntshav ntau yam myeloma. Yog vim li cas cov kws kho mob thiaj li saib xyuas cov neeg uas muaj tus mob no ze heev .

Puas muaj lwm yam mob uas ua rau mob multiple myeloma?

Yog, muaj lwm yam mob. Nws hu ua Monoclonal Gammopathy of Undetermined Significance (MGUS) . Ib yam li SMM, qhov no yog ib yam mob uas tuaj yeem tshwm sim ua ntej mob multiple myeloma tshwm sim. Cov kws kho mob xav tias MGUS (hais tias "M-gus") yog ib qho ua ntej mob multiple myeloma.

(SMM) cuam tshuam li cas rau kuv lub cev? Cov tsos mob yog dab tsi?

Nov yog qhov tseem ceeb: Feem ntau cov neeg uas muaj (SMM) tsis qhia cov tsos mob.Qhov ntawd txhais tau tias koj yuav tsis hnov ​​​​​​mob lossis tsis xis nyob. Cov neeg feem coob pom tias lawv muaj SMM thaum lawv kuaj ntshav tas li rau lwm qhov laj thawj. Cov kev kuaj ntshav ntawd yuav qhia tau tias koj muaj ib hom protein txawv txawv hu ua M proteins , uas yog tsim los ntawm cov hlwb plasma txawv txawv hauv koj lub cev.

Cov kev kuaj ntshav qhia tau tias cov qe ntshav dawb tsis zoo no tsim cov protein tiv thaiv kab mob tsis zoo (M proteins). Tsis tas li ntawd, yog tias koj ua qhov kev kuaj mob pob txha, cov kws kho mob tuaj yeem pom cov qe ntshav dawb tsis zoo no hauv cov pob txha. Txawm li cas los xij, thaum lub sijhawm "smokering" no, myeloma tsis ua rau muaj teeb meem hauv koj lub cev, yog li cov neeg uas muaj SMM feem ntau tsis muaj tsos mob dab tsi.

Leej twg thiaj li tau tus kab mob (SMM)? Qhov no puas yog ib qho kab mob uas neeg feem ntau kis tau?

Feem ntau tus mob no cuam tshuam rau cov neeg hnub nyoog tshaj 60 xyoo. Lub hnub nyoog nruab nrab thaum kuaj pom tias muaj tus mob no yog nyob nruab nrab ntawm 62 thiab 67 xyoo.

(SMM) tsis yog ib yam kab mob uas pom ntau. Cov kws tshawb fawb kwv yees tias nws tsuas cuam tshuam rau ib tus neeg hauv 100,000 tus xwb. Txawm li cas los xij, multiple myeloma tsuas cuam tshuam rau xya tus neeg hauv 100,000 tus xwb. Yog li, (SMM) yog ib yam mob uas tsis tshua muaj.

Qhov kev pheej hmoo ntawm kev mob (SMM) mus rau hauv mob multiple myeloma yog dab tsi?

Qhov no kuj tseem ceeb heev uas yuav tsum paub. Hauv tsib xyoos thawj zaug tom qab kuaj pom tias muaj SMM, kwv yees li 10% ntawm cov neeg uas muaj SMM yuav muaj mob multiple myeloma txhua xyoo. Hauv tsib xyoos tom ntej no, feem pua ​​ntawd yuav poob mus rau 3% ib xyoos. Tom qab 10 xyoo thawj zaug, qhov kev pheej hmoo no yuav poob ntxiv mus rau 1% ib xyoos.

Qhov no txhais tau tias tsis yog txhua tus neeg uas muaj (SMM) yuav mob multiple myeloma. Txawm li cas los xij, muaj kev pheej hmoo, yog li kev saib xyuas kev kho mob tsis tu ncua yog qhov tseem ceeb heev.

Puas muaj kev kuaj mob uas tuaj yeem kwv yees tau tseeb tias ib tug neeg puas yuav muaj mob multiple myeloma?

Tu siab kawg li, tam sim no tsis muaj kev kuaj mob uas yuav kwv yees tau tseeb tias ib tug neeg puas yuav muaj mob multiple myeloma. Cov kws kho mob thiab cov kws tshawb fawb tseem niaj hnub tshuaj xyuas cov kev hloov pauv ntawm cov noob caj noob ces uas cuam tshuam nrog mob multiple myeloma thiab tab tom nrhiav seb lawv puas tuaj yeem txheeb xyuas seb ib tug neeg uas muaj SMM puas yuav muaj mob multiple myeloma.

Cov laj thawj rau qhov tshwm sim ntawm (SMM) yog dab tsi?

Cov kws tshawb nrhiav paub tias cov hlwb plasma uas tsis zoo thiab cov khoom hu ua M proteins yog ib qho cim ntawm ntau yam myeloma (MM) thiab ntau yam myeloma (MM). Txawm li cas los xij, lawv tseem tsis tau paub meej tias yog dab tsi ua rau cov hlwb plasma uas zoo li qub thiab noj qab nyob zoo dhau los ua qhov tsis zoo. Lawv tab tom tshawb nrhiav qee qhov ua rau muaj:

• Kev hloov pauv ntawm cov noob caj noob ces: Cov kws tshawb fawb tab tom tshawb nrhiav seb puas muaj kev sib txuas ntawm kev hloov pauv hauv qee cov noob caj noob ces (oncogenes - cov noob caj noob ces uas txhawb kev loj hlob ntawm tes) thiab ntau yam mob myeloma (MM).
• Kev Rog Phem: Muaj kev xav tias cov rog hauv lub cev ntau dhau kuj yog ib qho tseem ceeb.

Yuav ua li cas thiaj paub (SMM)? Cov kev ntsuam xyuas twg ua?

Cov kws kho mob yuav ua ntau yam kev kuaj mob kom paub tseeb tias koj puas muaj tus mob no. Nco ntsoov tias, yog tias kev kuaj ntshav thiab/lossis zis ib txwm qhia cov cim ntawm M protein, qhov ntawd yuav yog thawj qhov cim qhia tias koj muaj multiple myeloma. Cov kws kho mob mam li ua qee qhov kev kuaj mob kom pom tias koj tus mob puas nce mus rau multiple myeloma. Cov kev kuaj mob no yuav suav nrog:

• Kev suav cov ntshav tag nrho (CBC): Qhov no ntsuas tus naj npawb ntawm cov qe ntshav liab, cov qe ntshav dawb, thiab cov platelets uas koj cov pob txha tsim tawm.
• Kev kuaj ntshav: Qhov no kuaj koj cov creatinine theem (los xyuas seb koj lub raum ua haujlwm zoo li cas), albumin theem (los xyuas seb koj lub raum thiab daim siab ua haujlwm zoo li cas), thiab calcium theem (los xyuas seb puas muaj pob txha poob).
• Kev kuaj ntshav immunoglobulin kom muaj nuj nqis: Kev kuaj ntshav no ntsuas cov protein M (cov protein tiv thaiv kab mob) hauv koj cov ntshav.
• Electrophoresis thiab serum immunofixation: Cov kev kuaj no nrhiav cov protein M hauv koj cov ntshav.
• Kev kuaj zis: Cov kws kho mob yuav hais kom koj khaws cov zis hauv tsev li 24 teev kom paub seb puas muaj cov protein M.
• Cov duab xoo hluav taws xob: Cov duab xoo hluav taws xob yog siv los saib seb puas muaj kev puas tsuaj rau pob txha vim yog ntau yam myeloma.
• Kev ntsuas Computed Tomography (CT): Qhov no yog lwm txoj hauv kev los pom kev puas tsuaj ntawm pob txha.
• Kev Siv Duab Xam Xaj Sib Nqus (MRI): Qhov kev kuaj no siv cov nthwv dej xov tooj cua thiab cov hlau nplaum muaj zog los ua cov duab ntxaws ntxaws ntawm koj cov pob txha thiab tus txha nqaj qaum. Qhov kev kuaj no siv tau los nrhiav pov thawj ntawm kev puas tsuaj thaum ntxov ntawm pob txha.
• Kev kuaj cov pob txha hauv cov nqaij: Cov kws kho mob tuaj yeem coj ib qho qauv ntawm koj cov pob txha thiab tshuaj xyuas nws kom pom feem pua ​​​​​​ntawm cov hlwb plasma zoo thiab tsis zoo hauv nws. Lawv kuj tuaj yeem kuaj xyuas cov qauv pob txha rau kev hloov pauv hauv koj cov DNA uas tuaj yeem ua rau mob qog noj ntshav.

Cov qauv rau (SMM) yog dab tsi?

Thaum cov kws kho mob tham txog "cov qauv," lawv txhais tau tias cov txiaj ntsig ntawm kev kuaj mob uas ua tau raws li cov qauv kho mob uas xav tau los ua qhov kev kuaj mob. Cov qauv rau (SMM) yog:

• Kev kuaj ntshav qhia txog qib M protein ntau dua 3g/dl (3 grams ib deciliter ntawm cov ntshav).
• Kev kuaj zis 24 teev qhia tias muaj 500 milligrams lossis ntau dua ntawm cov protein. Los yog...
• Kev kuaj cov pob txha hauv koj lub cev qhia tau tias cov hlwb ntshav muaj li ntawm 10% thiab 59% ntawm tag nrho cov hlwb ntshav hauv koj lub hlwb pob txha. Thiab...
• Tsis muaj cov cim qhia txog cov pob txha tsis zoo lossis lub raum puas tsuaj uas tuaj yeem tshwm sim los ntawm myeloma, koj cov qe ntshav dawb yog ib txwm muaj, thiab koj cov calcium yog ib txwm muaj.

Yuav kho tus mob no li cas?

Tam sim no, kev kho mob rau SMM yog "tos ntsoov." Qhov no suav nrog cov kws kho mob ua qhov kev kuaj mob tsis tu ncua los saib xyuas cov protein M hauv koj cov ntshav thiab cov hlwb ntshav hauv koj cov pob txha. Zoo li tus neeg saib xyuas, lawv tab tom saib xyuas seb tus kab mob puas hnyav zuj zus.

Tej zaum ib txhia neeg yuav muaj feem yuav mob multiple myeloma ntau dua . Hauv cov xwm txheej zoo li no, tej zaum ib txhia kws kho mob yuav pom zoo kom pib kho mob multiple myeloma thaum ntxov. Yog tias koj muaj multiple myeloma (MM), koj tus kws kho mob yog tus neeg zoo tshaj plaws los muab cov ntaub ntawv thiab cov lus qhia kho mob uas koj xav tau.

Kuv puas txo tau qhov kev pheej hmoo ntawm kev tsim (SMM)?

Tu siab kawg li, tam sim no tsis muaj txoj hauv kev los tiv thaiv kev tsim ntawm (SMM).

Koj yuav nyob tau ntev npaum li cas nrog (SMM)?

Txoj kev uas tus mob no cuam tshuam rau txhua tus neeg txawv. Tej zaum yuav muaj ib txhia neeg tab sis yeej tsis muaj mob multiple myeloma. Ib txhia neeg muaj mob multiple myeloma ntau lub hlis lossis ntau xyoo tom qab kuaj pom. Yog tias koj txhawj xeeb txog kev nyob nrog SMM, nug koj tus kws kho mob seb koj tuaj yeem cia siab li cas. Lawv yog cov neeg zoo tshaj plaws los muab cov ntaub ntawv tshwj xeeb rau koj.

Koj muaj peev xwm ua neej nyob tau ntev npaum li cas nrog rau ntau yam mob myeloma?

Qhov no kuj yog ib qho teeb meem rau ntau tus neeg. Kwv yees li ntawm 40% txog 82% ntawm cov neeg uas muaj mob multiple myeloma tseem muaj sia nyob tsib xyoos tom qab kuaj pom. Qhov no nyob ntawm ntau yam, suav nrog hom kab mob thiab kev teb rau kev kho mob.

Kuv yuav ua li cas thiaj saib xyuas kuv txoj kev noj qab haus huv?

Yog tias koj muaj mob multiple myeloma, tej zaum koj yuav tsis tas yuav kho tam sim ntawd - lossis tsis tas yuav kho li. Koj tus kws kho mob yuav qhia koj kom tuaj kuaj xyuas tsis tu ncua. Qhov no yog los xyuas seb koj tus mob puas tau hloov mus ua mob multiple myeloma. Kev nyob nrog mob multiple myeloma tuaj yeem ua rau ntxhov siab thiab ntxhov siab . Tej zaum koj yuav xav tias, "Auj, kuv xav tias kuv ua tau ib yam dab tsi txog qhov no." Qhov ntawd yog ib txwm muaj. Tab sis muaj qee yam uas koj tuaj yeem ua tau los saib xyuas koj txoj kev noj qab haus huv tag nrho:

• Noj zaub mov kom zoo. Yog tias koj tsis paub meej txog qhov no, nrog tus kws noj haus tham.
• Yog koj haus luam yeeb, thov sim tso tseg.
• So kom txaus.
• Tiv thaiv koj tus kheej kom tsis txhob muaj kab mob. Nug koj tus kws kho mob txog cov hau kev los tiv thaiv kab mob.
• Ua si nawv tsis tu ncua.Tiamsis, nrog koj tus kws kho mob tham ua ntej thiab nug seb hom kev tawm dag zog twg yog qhov zoo rau koj thiab koj yuav tsum ua ntau npaum li cas. Nws kuj tsis zoo rau kev ua ntau dhau.
• Ua tib zoo saib xyuas koj txoj kev noj qab haus huv ntawm lub hlwb thiab. Yog tias koj tu siab lossis nyuaj siab txog koj tus mob, nrog koj tus kws kho mob tham txog qhov ntawd. Nco ntsoov qhia rau lawv, tshwj xeeb tshaj yog tias qhov kev tu siab lossis kev nyuaj siab kav ntev tshaj ob lub lis piam lossis cuam tshuam rau koj cov dej num txhua hnub.

Kuv yuav tsum nug kuv tus kws kho mob li cas?

Yog koj muaj (SMM), ntawm no yog qee cov lus nug uas koj tuaj yeem nug koj tus kws kho mob:

• Vim li cas qhov no thiaj tshwm sim rau kuv?
• Qhov no cuam tshuam li cas rau kuv lub neej txhua hnub?
• Yuav siv sijhawm ntev npaum li cas rau tus kab mob multiple myeloma thiaj li loj hlob tuaj?
• Puas muaj tej yam tsos mob tshwj xeeb uas yuav qhia tau tias muaj mob multiple myeloma, thiab kuv puas yuav tsum paub txog lawv?
• Puas muaj kev kho mob los tiv thaiv tus mob (SMM) kom tsis txhob loj hlob mus ua ntau yam mob myeloma?

Thaum kawg, yuav tsum nco ntsoov li cas (Cov Lus Coj Mus Tsev)

Mob Multiple Myeloma uas kub hnyiab (SMM) yog ib qho mob ua ntej mob qog nqaij hlav ntawm mob multiple myeloma (MM). Txawm li cas los xij, tsis yog txhua tus neeg uas muaj mob SMM yuav mob multiple myeloma uas tseem muaj sia nyob. Cov neeg uas muaj mob SMM feem ntau xav paub seb lawv puas yuav mob multiple myeloma uas tseem muaj sia nyob, thiab yog tias muaj, yuav mob thaum twg. Cov lus nug no nyuaj teb heev. Cov kws kho mob tseem tsis tau muaj tag nrho cov lus teb.

Txawm li cas los xij, kev tshawb fawb tsis ntev los no qhia tau hais tias los ntawm kev kos duab kev hloov pauv hauv qee cov noob caj noob ces, nws yuav ua tau los kwv yees qee yam seb (SMM) puas yuav loj hlob mus ua ntau yam mob myeloma, thiab yog tias yog, thaum twg.

Yog koj muaj tus mob no, nug koj tus kws kho mob yog tias muaj cov ntaub ntawv tshiab txog koj tus mob. Lawv yuav zoo siab pab koj. Qhov tseem ceeb tshaj plaws yog ua raws li koj tus kws kho mob cov lus qhia thiab ua kom lub siab muaj zog.

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