enibodi na yu fambul geht "Sickle Cell Disease"? Mek wi no fɔ tru!

Tide wi go tɔk bɔt wan kɔndishɔn we nyu smɔl to bɔku pipul dɛn, bɔt kin rili nia sɔm famili. Dɛn kɔl am Siklɔs Sɛl Diziz (SCD). Sɔntɛm yu dɔn yɛri dis nem bifo. Fɔ tru, na sik we gɛt fɔ du wit wi blɔd, dat min se i gɛt fɔ du wit di blɔd, ɛn we pɔsin kin gɛt frɔm wi gret gret granpa. Lɛ wi tek tɛm luk wetin i rili bi, wetin mek i kin apin, ɛn wetin ɔda tin dɛn kin du bɔt am.

Wetin na Siklɔs Sɛl Sik? Lɛ wi ɔndastand am simpul wan!

Fɔ tɔk am simpul wan, sikɛl sɛl sik (SCD) na sik we kin afɛkt di rɛd blɔd sɛl dɛn na wi bɔdi, we mama ɛn papa kin gɛt frɔm pikin dɛn. Dis na wan pan di blɔd sik dɛn we pɔsin kin gɛt frɔm in mama ɛn papa na di wɔl. Naw luk, insay wi rɛd blɔd sɛl dɛn, wan prɔtin de we dɛn kɔl ɛmoglobin . Dis ɛmoglobin rili impɔtant. Bikɔs, na dis prɔtin de kɛr ɔksijɛn ɔlsay na wi bɔdi. I tan lɛk ɔksijɛn taksi. Bɔku tɛm, di rɛd blɔd sɛl dɛn na pɔsin we gɛt wɛlbɔdi kin rawnd ɛn i kin ebul fɔ chenj. Lɛk smɔl smɔl rɔba bɔl dɛn. bikɔs ɔf dis, i izi fɔ mek dɛn kray tru di smɔl smɔl blɔd vesel dɛn na di bɔdi (wi kin kɔl dɛn kapilari) ɛn gi ɔksijɛn to ɔl wi ɔgan ɛn tisu dɛn. Bɔt wetin kin apin to pɔsin we gɛt siklɛt sik na dat, dis ɛmoglobin kin chenj smɔl. Dis abnɔmal ɛmoglobin na in dɛn kɔl ɛmoglobin S. Dis kin mek di rɛd blɔd sɛl dɛn tan lɛk kres, ɔ af mun, instead fɔ bi rawnd ɛn fleksibul. Nɔto dat nɔmɔ, dɛn sɛl ya kin rili stif, dɛn nɔ kin bɛn izi wan, ɛn dɛn kin stik togɛda. Imajin, wetin kin apin we dɛn sɛl dɛn ya we tan lɛk sikl de travul tru dɛn smɔl smɔl blɔd vesel dɛn de? Dɛn kin stɔp! Dɔn di blɔd kin ambɔg. Dat min se, wi ɔgan ɛn tisu dɛn we impɔtant pas ɔl nɔ kin gɛt inof ɔksijɛn. Dis na di rizin we mek siriɔs prɔblɛm dɛn lɛk bad bad pen, difrɛn infɛkshɔn, ɔgan dɛn we de pwɛl, ɛn we nɔ de wok fayn kin apin. Wan ɔda tin na dat, dɛn sɛl dɛn ya we tan lɛk sikl nɔ de liv lɔng lɛk di nɔmal rɛd blɔd sɛl dɛn. Dɛn kin day kwik kwik wan. Dɔn di bɔdi nɔ kin gɛt bɛtɛ rɛd blɔd sɛl ɔltɛm. Dis na wetin wi kɔl anemia . Siklɔs sik na sik we pɔsin kin gɛt fɔ ɔl in layf. Bɔt nɔ wɔri, tritmɛnt dɛn de fɔ dis. Wit dɛn tritmɛnt ya, yu kin ridyus de sik ɛn lɔng yu layf.

Difrɛn kayn sik dɛn de we gɛt sik?

Yɛs, bɔku kayn sik dɛn de we dɛn kɔl sikɛl sɛl. Dɛn kayn tin ya kin bi bay di jin dɛn we pɔsin kin gɛt frɔm in mama ɛn papa.

Ɛmoglobin SS (HbSS) .

Dis na di kayn sik wae kin pasmak pan sik. Na lɛk 65% pan di pipul dɛm wae gɛt SCD gɛt dis kayn. Dɛn pipul ya kin gɛt di ɛmoglobin S jin frɔm dɛn mama ɛn papa dɛn ɔl tu. Dis min se bɔku ɔ ɔl dɛn ɛmoglobin nɔ de wok fayn. Dis kin mek dɛn gɛt anemia we nɔ de dɔn.

Ɛmoglobin SC (HbSC) .

Dis na tin we nɔ kin apin ɔ we nɔ kin bɔku.Wan kayn we de na ay levul. Na lɛk 25% pan di pipul dɛm wae gɛt SCD gɛt dis. Dɛn pipul ya kin gɛt di ɛmoglobin S jin frɔm wan mama ɛn papa ɛn di jin fɔ ɔda abnɔmal ɛmoglobin tayp we dɛn kɔl ɛmoglobin C frɔm di ɔda mama ɔ papa.

Ɛmoglobin (HbS) Bɛta Talasɛmia

Dɛn pipul ya kin gɛt wan ɛmoglobin S jin frɔm wan mama ɛn papa ɛn wan abnɔmal jin we dɛn kɔl beta thalassemia frɔm di ɔda mama ɛn papa. Tu sɔbtayp dɛn de bak fɔ dis:

• “Plus” (HbS beta +): Dis na wan kayn wae de afekt lɛk 8% pan pipul dɛm wae gɛt SCD ɛn i kin ɔltɛm bi smɔl.
• “Zero” (HbS beta 0): Dis na wan kayn we de afɛkt lɛk 2% pan pipul dɛm wae gɛt SCD ɛn i kin tranga lɛk ɛmoglobin SS (HbSS) sik.

Ɔda kayn dɛn we nɔ bɔku

Apat frɔm dis, ɔda kayn dɛn de we nɔ kin bɔku lɛk ɛmoglobin SD (HbSD), ɛmoglobin SE (HbSE), ɛn ɛmoglobin SO (HbSO) . Dɛn pipul ya kin gɛt wan ɛmoglobin S jin ɛn ɔda abnɔmal jin we dɛn kɔl D, E, ɔ O.

Wetin na di difrɛns bitwin Siklɔs Sɛl Anemia ɛn Siklɔs Sik?

Dis na di say we bɔku pipul dɛn kin kɔnfyus. Siklɔs sik (SCD) na wan jɛnɛral wɔd fɔ ɔl di difrɛn kayn sik dɛn we wi dɔn tɔk bɔt ɔp. I tan lɛk ambɔla. Ɔl di ɔda kayn dɛn kin fɔdɔm ɔnda da ambɔla de. Dɔktɔ dɛn kin jɔs yuz di wɔd "Sickle Cell Anemia" fɔ di kayn SCD we rili bad we kin mek pɔsin gɛt anemia . Dat min se di kayn dɛn we dɛn kɔl ɛmoglobin SS (HbSS) ɛn ɛmoglobin beta ziro talasɛmia. Dɔn gɛt am?

Wetin na di difrɛns bitwin Siklɔs Trayt ɛn Sik?

Sɔm pipul dɛn gɛt di siklɛt kwaliti nɔmɔ . Dis min se na wan mama ɔ papa nɔmɔ dɛn kin gɛt di ɛmoglobin S jin . Di ɔda mama ɔ papa gɛt wɛlbɔdi jin. Bɔrku tɛm, pipul dɛm wae gɛt siklɛt trayt nɔr kin sho sayn dɛm fɔ siklɛt sik. Bɔt dɛn kin pas dis abnɔmal jin to dɛn pikin dɛn. Dis min se na dɛn de kɛr dis jin. Bɔt nɔto ɔltɛm ivin pipul dɛn we gɛt siklɛt abit kin gɛt wɛlbɔdi prɔblɛm if dɛn nɔ gɛt bɛtɛ wata na dɛn bɔdi ɔ if dɛn de du ɛksɛsayz tranga wan . Risach stil de go bifo pan dis.

Aw kɔmɔn sik na sik?

Risach pipul dɛn se na lɛk 100,000 pipul dɛn na Amɛrika nɔmɔ gɛt sik we dɛn kɔl sikɛl. I kin bɔku pan pipul dɛn we kɔmɔt na Afrika. I de bak pan Hispanik Amɛrikin dɛm, ɛn pipul dɛm we kɔmɔt na Mɛditarenian, Midul Ist, Indian, ɛn Eshia. Pipul dɛn de bak we gɛt dis sik na Sri Lanka.

Wetin kin mek pɔsin gɛt sik we dɛn kɔl sikɛl sɛl?

Siklɔs sik kin kam bikɔs ɔf wan jɛnɛtik muteshɔn na wan jin we dɛn kɔl di HBB jin . dis HBB jin de mek wan pat pan di εmoglobin. Pipul dεm we gεt SCD kin gεt tu mכtayt HBB jin dεm we de mek abnכmal εmoglobin – wan frכm εvri mama εn papa. dis dεn kכl am כtosom rεsεsiv inhεritεns. dis min se dεn tu mama εn papa fכ pikin we gεt SCD de kכri wan kכpi fכ di mutated jin (we min se dεn kin gεt di sikl sεl trayt). Bɔt bɔku tɛm, dɛn mama ɛn papa dɛn de nɔ kin sho di sik.

Udat dɛn gɛt bɔku risk fɔ gɛt siklɛt sik (SCD)?

Sɔm grup pan pipul dɛn kin gɛt dis sik. Dɛn na:

• Pipul dɛn we kɔmɔt na Afrika (e.g. Afrikan Amɛrikin dɛn).
• Hispanik Amɛrikin dɛn na Sawt Amɛrika ɛn Sɛntral Amɛrika.
• Pipul dɛn we kɔmɔt na Mɛditarenian, Midul Ist, Indian, ɛn Eshia.

Wetin na di sayn dɛm wae de sho se yu gɛt siklɛt sik?

di sayn dεm fכ sik sεl sik kin bigin fכ sho we pikin ol lεk 5 to 6 mכ nt. Dɛn sayn ya kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Sɔm pipul dɛn kin gɛt sɔm kayn sik wae nɔr kin izi fɔ dɛn, ɛn ɔda wan dɛn kin gɛt siriɔs prɔblɛm. De men sayn wae yu kin si na:

• Di pen we kin apin ɔltɛm.
• Anemia : Dis kin mek yu taya pasmak, yu nɔr kin gɛt bɛtɛ blɔd, ɛn yu kin wik.
• Jaundice : Di skin kin yɔlɔ ɛn di yay kin wayt.
• Di an ɛn fut dɛn we de swel we de mek yu fil pen.

Wetin na de prɔblɛm wae kin kam wit dis sik?

Siklɔs sik kin afɛkt bɔku pat dɛn na di bɔdi. Sɔm ifɛkt kin bigin wantɛm wantɛm (akyu), ɔda wan dɛn kin las fɔ lɔng tɛm (krɔnik). Dɛn kɔmplikeshɔn ya kin bigin kwik ɛn las fɔ ɔl yu layf.

Pen

Dis na di kɔmplikeshɔn we kin kam wit siklɛt sik. Di pen kin apin we di sɛl dɛn we tan lɛk sik kin stɔp na di blɔd vesel dɛn ɛn blok di blɔd fɔ flɔ. Yu kin gɛt bad bad pen wantɛm wantɛm. Dɛn kin kɔl dis bak pen kraysis, siklɛs sɛl kraysis, vaso-occlusive crisis (VOC), ɔ vaso-occlusive episode (VOE) . Dɛn pen krɛse ya kin smɔl ɔr kin tranga, ɛn kin bigin wantɛm wantɛm ɛn las fɔ ɛni lɔng tɛm. Bɔrku tɛm, de pen kin de na di chɛst, bak, leg, ɛn an. Sɔm pipul dɛn kin gɛt pen we nɔ de dɔn , we min se dɛn kin gɛt pen we kin te pas siks mɔnt.

Anemia we nɔ gɛt bɛtɛ blɔd

Siklɔs sik kin mek pɔsin nɔ gɛt bɛtɛ blɔd bikɔs di rɛd blɔd sɛl dɛn kin day tumɔs. Anemia na we yu nɔ gɛt wɛlbɔdi rɛd blɔd sɛl dɛn we kin kɛr ɔksijɛn ɔlsay na di bɔdi. Dis na di rizinYu kin taya pasmak, yu kin gɛt janda, yu nɔ kin rɛst, yu kin gɛt diziz, ɛn yu ed kin gɛt layt.

Akyu Chɛst Sindrom we pɔsin kin gɛt

Dis na mɛdikal imejensi we kin mek pɔsin in layf de pan denja . I kin pwɛl di lɔng dɛn, i kin mek i nɔ izi fɔ blo, ɛn i kin mek di ɔksijɛn nɔ de go ɔda pat dɛn na di bɔdi. dis komplikashכn kin apin we sik sεl dεm de blכk di fכ fכlכ bכdi εn כksijεn to di lכng dεm.

Blɔd we De Klɔt

Sikl sɛl anemia kin mek di blɔd klɔt mɔ ɛn mɔ. dis de mek di risk fכ divεlכp bכdi kכlכt na dip vein (dip vein thrombosis - DVT). DVT kin brok bak εn i kin lod na di lכng dεm (pulmonary embolism - PE).

Strok

If siklɛt sɛl dɛn stɔp na blɔd vesel we de go na di bren, blɔd kin blok to di bren. Di bren nɔ de gɛt inof ɔksijɛn fɔ mek i ebul fɔ wok. Dis kin mek pɔsin gɛt strok . Na lɛk 10% pan di pipul dɛm wae gɛt SCD go gɛt klinik strok. Pipul wae gɛt siklɛt anemia kin gɛt bɔrku risk fɔ gɛt strok.

Prɔblɛm dɛn we kin apin we pɔsin de si

Siklɔs kin blok di blɔd vesel dɛn na di yay. dis kin apin bכku tεm na di rεtina . Sɔmtɛm, no sayn nɔr kin de ɛn afta dat, yu kin lɔs yu yay wantɛm wantɛm, ɛn i kin ivin mek yu blaynd fɔ ɔltɛm.

Priapism we dɛn kɔl priapism

Priapism na di kכndyushכn we di sεl dεm we lεk sikl na man in penis kin blok, we kin mek i εrekshכn kכntinyu, we de mek i fil pen ( priapism ). Apat frɔm di pen, priapism kin mek pɔsin gɛt damej fɔ ɔltɛm ɛn i kin mek i nɔ ebul fɔ tinap tranga wan . Priapism we de te pas 4 awa na mɛdikal imejensi.

Ɔgan dɛn we dɔn pwɛl ɛn we nɔ de wok fayn

Pipul wae gɛt siklɛt sik kin gɛt prɔblɛm wit dɛn at, lɔng, kidni, ɛn ɔda ɔgan dɛm bikɔs dɛn nɔr kin gɛt inof blɔd ɛn ɔksijɛn. SCD kin mek bɔku ɔgan dɛn nɔ wok .

Yu tink se siklɛt trayt ɔ sik kin afɛkt uman we gɛt bɛlɛ?

Bɔku uman dɛn we gɛt siklɛt sik kin gɛt bɛlɛ we gɛt wɛlbɔdi. Bɔt di prɔblɛm dɛn we kin apin kin bɔku. SCD kin mek di risk fɔ gɛt ay blɔd prɛshɔn, blɔd klɔt, fɔ gɛt bɛlɛ, fɔ bɔn pikin dɛn we nɔ gɛt bɔku wet, ɛn fɔ bɔn pikin dɛn bifo tɛm . So i impɔtant fɔ fala yu dɔktɔ in advays.

Aw dɛn kin no se sik na sik?

Insay Sri Lanka, lɛk bɔku kɔntri dɛn ɔlsay na di wɔl, dɛn kin chɛk ɛni pikin we dɛn jɔs bɔn fɔ siklɛt sik as pat pan di skrinin we dɛn kin du fɔ chɛk di pikin dɛn we dɛn jɔs bɔn . Dis min se dɛn kin tek smɔl blɔd na di pikin in il ɛn tɛst am. Dis kin chɛk bak fɔ bɔku ɔda sik dɛn. Fɔ mek dɛn no se i gɛt di sik, di pikin in dɔktɔ go du wan tɛst we dɛn kɔl ɛmoglobin ilɛktrɔfɔrɛsis . Dɔn bak, dɛn kin no siklɛt sik bifo dɛn bɔn di pikin bay we dɛn de tɛst am bifo dɛn bɔn am . Dɛn tɛst ya na:dis dεm inklud di chorionic villus sampling εn amniocentesis .

Yu tink se wan kɔmplit mɛrɛsin de fɔ siklɛt sik?

Yɛs, if pɔsin transplant bon mɛro , we dɛn kin kɔl bak stem sɛl transplant, i kin mɛn siklɛt sik. Dis involv fɔ tek wɛlbɔdi bon mɛrɔ frɔm pɔsin we gɛt wɛlbɔdi, we gɛt jɛnɛtiks kɔmpitishɔn (lɛk brɔda ɛn sista) ɛn transplant am to di pɔsin. Bɔt na lɛk 18% pan di pipul dɛn we gɛt SCD kin fɛn dis kayn mach. Risk ɛn kɔmplikɛshɔn dɛn de bak fɔ dis transplant. Yu dɔktɔ go tɔk bɔt dis wit yu.

Wetin na di tritmɛnt fɔ siklɛt sik?

Di tritmɛnt fɔ siklɛt sik na fɔ tek mɛrɛsin, blɔd transfyushɔn, bon mɛro transplant, ɛn jin tɛrapi . Dɛn kin bigin fɔ trit am wit antibayɔtik . Dɛn kin gi nyu bɔbɔ dɛn we gɛt siriɔs SCD antibayɔtik tu tɛm insay di de fɔ te 5 ia fɔ mek dɛn nɔ gɛt di sik.

Ɔda mɛrɛsin dɛn

Bɔrku pipul dɛm wae gɛt SCD kin yuse mɛrɛsin fɔ ridyus dɛn sik ɛn trit di sayn dɛm. Sɔm pan dɛn tin ya na:

• Voxelotor: Dis kin mek di rεd bכ di sεl dεm nכ de lεk sikl εn stכk togeda. Dis kin mek sɔm rɛd blɔd sɛl dɛn nɔ pwɛl, i kin mek di blɔd flɔ fayn fayn wan to di ɔgan dɛn, ɛn i kin mek i nɔ gɛt bɔku blɔd.
• Crizanlizumab: Dis mɛrɛsin de ɛp fɔ mek di rɛd blɔd sɛl dɛn we tan lɛk sikl nɔ stik na di wɔl dɛn na di blɔd vesel dɛn . Dis kin mek di blɔd flɔ fayn ɛn i kin mek di inflamɛns ɛn pen nɔ bɔku.
• Hydroxyurea : Dis kin ridyus ɔ mek sɔm prɔblɛm dɛn we kin kam wit SCD, lɛk fɔ gɛt pen ɔltɛm, akyu chɛst sindrom, ɛn siriɔs anemia.
• L-glutamine: Dis na tin we de mek pɔsin nɔ fil pen. E kin ɛp fɔ ridyus di nɔmba fɔ di pen atak dɛm wae yu gɛt. Ɔda tin dɛn we kin mek pɔsin nɔ fil pen na nɔ-stɛroyd anti-inflammatory drugs (NSAID) ɛn opiate .

Blɔd we dɛn kin gi pɔsin

Yu dɔktɔ kin tɛl yu fɔ tek sɔm blɔd fɔ trit ɛn mek yu nɔ gɛt prɔblɛm dɛn we kin kam wit SCD.

• Akyu transfyushɔn:Dɛn tin ya kin ɛp fɔ trit prɔblɛm dɛn we kin mek pɔsin gɛt siriɔs anemia. Dɔktɔ dɛn kin yuz dɛn bak fɔ krayse lɛk strok, akyu chɛst sindrom, ɛn ɔgan dɛn we nɔ de wok fayn.
• Rɛd blɔd sɛl transfyushɔn: Dɛn tin ya kin mek di rɛd blɔd sɛl dɛn bɔku na di bɔdi ɛn gi nɔmal rɛd blɔd sɛl dɛn we nɔ tan lɛk sik.

Stem sel transplant (dεn kin kכl am bak bon mכro transplant) .

SCD kin kכmכt wit stεm sεl transplant. Dis nid fɔ gɛt pɔsin we fit fɔ gi mɔni (lɛk brɔda ɛn sista). Risach de go bifo bak fɔ mek dɛn ebul fɔ transplant frɔm mama ɛn papa ɔ brɔda ɛn sista dɛn we nɔ tu mach. Yu dɔktɔ go tɔk bɔt di prɔblɛm dɛn ɛn di bɛnifit dɛn we dis tritmɛnt go gi yu bay di patikyula tin we de apin to yu.

Jin Tɛrapi

Naw, risechar dɛm de invɛstigat jin tɛrapi fɔ trit SCD. Dis min se yu fɔ kɔrɛkt di ɛmoglobin jin we nɔmal ɔ fɔ put wɛlbɔdi ɛmoglobin jin insay pɔsin in stem sɛl dɛn. Di fɔs data bɔt dis rili prɔmis. Di op na dat, wan de, jin tɛrapi go bi wan rutin tritmɛnt fɔ SCD.

Yu tink se dɛn go ebul fɔ stɔp dis?

Siklɔs sik na wan sik we pɔsin kin gɛt frɔm in jɛnɛtiks, so dɛn nɔ go ebul fɔ avɔyd am . If yu gɛt bɛlɛ, i go fayn fɔ mek yu tɔk to yu dɔktɔ bɔt aw fɔ tɛst yu jɛnɛtiks ɔ aw fɔ advays yu bɔt yu jɛnɛtiks . Dis go ɛp yu ɛn yu patna fɔ no if yu gɛt di jin ɛn wetin na yu risk fɔ pas am to yu pikin dɛn.

Wetin pɔsin we gɛt siklɛt sik kin ɛkspɛkt?

Pipul wae gɛt siklɛt sik kin gɛt shɔt layf fɔ lɔng pas di jenɛral pipul dɛm. Bɔt nyu tritmɛnt fɔ SCD dɔn rili ɛp fɔ mek pipul dɛn liv lɔng ɛn fɔ mek dɛn liv bɛtɛ layf . If dɛn mɛn di sik fayn fayn wan, pipul dɛn we gɛt siklɛt sik kin liv te dɛn rich 50 ia.

Aw a go kia fɔ mi pikin if i gɛt siklɛt sik?

If yu pikin gɛt siklɛt sik, bɔku tin dɛn de we yu kin du fɔ kɔntrol in kɔndishɔn:

• Tek yu pikin go to dɔktɔ ɔltɛm.
• Gi yu pikin ɔl di vaysin dɛn we dɛn dɔn rɛkɔmɛnd di rayt tɛm.
• Ɛp yu pikin fɔ ɛksesaiz ɔltɛm ɛn it tin dɛn we go ɛp in at .
• We pen kraysis apin, gi yu pikin bɔku wata ɛn wan nonsteroidal anti-inflammatory drug (NSAID) . If yu nɔ ebul fɔ kɔntrol di pen na os, kɛr yu pikin go na ɔspitul fɔ gɛt strɔng mɛrɛsin fɔ mɛn di pen.

Ustɛm yu nid fɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) ?

Siklɔs sik kin kam wit difrɛn prɔblɛm dɛn we kin mek pɔsin in layf de pan denja. If yu ɔ yu pikin gɛt ɛni wan pan dɛn sik ya, kɔl 911 ɔ go na di imejensi rum (ER) we de nia yu wantɛm wantɛm:

• I kin fil pen bad bad wan.
• Di sayn dɛm fɔ siriɔs anemia: yu kin taya pasmak, yu kin gɛt diziz, ɛn yu nɔ kin ebul fɔ blo fayn.
• Fiva pas 101.3 digri F (38.5 digri sɛlshiɔs).
• Prɔblɛm dɛn we pɔsin kin gɛt we i de si.
• I nɔ kin izi fɔ yu fɔ blo.
• di penile erection we de las fכ awa כ mכr (priapism).
• Di sayn dɛm fɔ akyu chɛst sindrom: chɛst pen, kɔf, fiva.
• Di sayn dɛm we de sho se pɔsin gɛt strok: Wan say na di bɔdi kin wik wantɛm wantɛm, i kin swɛla, ɛn i nɔ kin no natin.

Wetin mek siklɛt sik kin mek pɔsin fil pen?

Fɔ tɔk am simpul wan, di rɛd blɔd sɛl dɛn we tan lɛk sikl tan lɛk di lɛta C, ɔ wan kres mun. As dɛn de travul tru yu blɔd vesel dɛn, dɛn kin stɔp ɛn blok di blɔd fɔ flɔ. Na da tɛm de di pen kin apin. Tink bɔt am lɛk se trafik jam na rod.

Siklɔs na sik we pɔsin kin gɛt we i de fɛt insɛf?

Nɔ, pan ɔl we siklɛt sik gɛt sɔm pan di tin dɛn we kin mek pɔsin gɛt sik dɛn we i de fɛt insɛf , dɔktɔ dɛn nɔ kin tek SCD as sik we pɔsin kin gɛt we i de fɛt insɛf. Dɛn kin tek SCD as wan jenɛtik kɔndishɔn .

Siklɔs sik na sik we pɔsin kin gɛt fɔ ɔl in layf. Stɛm sɛl transplant, we kin gi pɔsin kɔmplit mɛn, nɔ kin pɔsibul ɔltɛm, ɛn i kin gɛt prɔblɛm. Bɔt if yu no di sik kwik kwik wan ɛn trit yu, dat kin ɛp fɔ ridyus di sayn dɛm ɛn ridyus di risk fɔ gɛt prɔblɛm. If yu de kia fɔ yu ɔltɛm, yu go ebul fɔ liv ful-ɔp ɛn aktif layf.

Fɔ dɔn, sɔm impɔtant tin dɛn we yu fɔ mɛmba (Take-Home Message) .

Okay, so wi don tok plenti boht sikle sel sik. Na sɔm impɔtant tin dɛn we yu fɔ mɛmba:

• Sikl sɛl sik (SCD) na wan sik we pɔsin kin gɛt frɔm in blɔd we di rɛd blɔd sɛl dɛn shep kin chenj, ɛn dis kin mek i gɛt prɔblɛm wit di blɔd we de flɔ.
• di men rizin fכ dis na wan abnכmal kayn εmoglobin we dεn kכl εmoglobin S.
• Pen, anemia, infεkshכn, εn כgan dεm we de pwεl na kכmכn.
• Fɔ no am kwik kwik wan ɛn fɔ trit am fayn fayn wan rili impɔtant. Dɛn kin chɛk nyu bɔn pikin dɛn fɔ dis.
• Pan ɔl we fɔ transplant bon mɛrɔ kin bi mɛrɛsin, i nɔ fayn fɔ ɔlman. Ɔda tritmɛnt dɛn de, lɛk mɛrɛsin ɛn blɔd transfyushɔn.
• Yu kin liv fayn wit dis sik bay we yu chenj yu layf, fala di rayt advays we dɔktɔ gi yu, ɛn du sɔntin kwik kwik wan if ɛnitin apin we nɔ izi fɔ yu .

If yu ɔ pɔsin we yu sabi gɛt ɛni kwɛstyɔn bɔt siklɛt sik, mek shɔ se yu go to dɔktɔ fɔ advays. Natin nɔ de fɔ fred ɔ shem. Di tin we impɔtant pas ɔl na fɔ mek dɛn no bɔt am! Siklɔs sik, ɛmoglobin, rɛd blɔd sɛl, anemia, jɛnɛtik sik, pen kraysis, siklɔs tritmɛnt