Yu ɔ pɔsin we yu sabi dɔn ɛva gɛt sɔm pat dɛn na yu bɔdi we swel wantɛm wantɛm, mɔ yu fes, yu lip, yu tɔŋ, ɔ yu an ɛn fut dɛn, we nɔ gɛt ɛni pen? Sɔntɛnde dis swɛlin kin ivin mek i nɔ izi fɔ blo. Wi kin kɔl dis kɔndishɔn Angioedema. Tide wi de tɔk bɔt wan spɛshal vaysin we dɛn kin gi fɔ mek dɛn nɔ gɛt di swɛlin atak we kin apin na dis kɔndishɔn. Dɛn kɔl am di C1 Inhibitor, Human vaysin.
Fɔ tɔk am simpul wan, wetin na dis C1 Inhibitor vaysin?
C1 Inhibitor na rili wan protin we na nכmal tin we dεn de mek na כl wi bכdi. I de kɔntrol sɔm pan di tin dɛn we de apin na wi imyun sistɛm. כltu, fכ sכm pipul dεm, biכs fכ jεnεtik rizin (dεn kכl dis Hεreditary Angioedema) כ כda rizin dεm, dis C1 Inhibitor protin nכ de prodyuz na di bכdi insay inof kwantiti. Na da tɛm de di swɛlin kin apin wantɛm wantɛm lɛk aw wi bin dɔn tɔk.
So, wetin dis vaksin de du na fכ gi di bכdi di C1 Inhibitor protin we nכ de. Dɛn kɔl dis vaysin ‘Mɔtalman’ bikɔs dɛn kin klin am frɔm di plasma pat pan mɔtalman blɔd ɛn dɛn kin mek am afta wan spɛshal prɔses. Yu kin fɛn dis mɛrɛsin na di makit ɔnda brand nem dɛn lɛk Cinryze ɔ HAEGARDA.
Di tin we impɔtant pas ɔl na dat, dɛn kin yuz dis mɛrɛsin fɔ mek dɛn nɔ gɛt atak we dɛn kɔl angioedema.
Tin dɛm we yu fɔ rili tɛl yu dɔktɔ bifo yu tek dis mɛrɛsin
Bifo yu gi yu dis mɛrɛsin, yu dɔktɔ fɔ no bɔt yu kɔmplit wɛlbɔdi histri. Mek shɔ se yu tɛl dɛn if yu gɛt ɛni wan pan dɛn tin ya:
- Blɔd klɔt disɔda: If yu bin dɔn gɛt blɔd klɔt disɔda bifo, lɛk we blɔd klɔt na wan vein na yu leg (DVT - Deep Vein Thrombosis) ɔ strok.
- Alɛji: If yu gɛt alɛji to di C1 Inhibitor vaysin ɔ ɛni ɔda mɛrɛsin, it, ɔ tin dɛn we de mek yu nɔ pwɛl.
- Bɛlɛ: If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu de gi pikin in bɛlɛ.
Bay dis infɔmeshɔn, yu dɔktɔ go disayd if dis mɛrɛsin fayn fɔ yu ɛn aw fɔ gi am.
Aw fɔ yuz di mɛrɛsin?
Dɛn kin gi dis mɛrɛsin mɔ tu we dɛn.
1. Infushכn insay vein: Na we fכ gi sכlushכn lεk salin insay vein.
2. Injεkshכn כnda di skin: Na sכm injεkshכn we dεn gi כnda di skin.
Na ɔspitul ɔ klinik kin gi yu dis mɛrɛsin. Bɔt sɔm tɛm, yu kin nid fɔ tek dis mɛrɛsin na os. If na so i bi, dɛn go gi yu di rayt trenin bɔt aw fɔ pripia di mɛrɛsin ɛn aw fɔ injɛkt am kɔrɛkt wan . I rili impɔtant fɔ tek di mɛrɛsin di rayt tɛm ɛn di rayt doz, lɛk aw yu dɔktɔ tɛl yu.
If yu de yuz am na os, tink bɔt dis bak.
If yu de yuz nidul ɛn sirinj na os, nɔ trowe dɛn na dɔti afta yu dɔn yuz am. Yuz wan kɔntena we gɛt shap tin dɛn. If yu nɔ gɛt wan, aks yu dɔktɔ bɔt aw fɔ gɛt wan. Dis impɔtant fɔ yu sef, yu famili, ɛn di say we yu de.
Sɔm sayd ɛfɛkt dɛn we dis mɛrɛsin kin gɛt
Lɛk ɛni mɛrɛsin, dis wan kin gɛt sɔm bad bad tin dɛn. Bɔt nɔto ɔlman kin gɛt dɛn. Lɛ wi sheb dɛn sayd ɛfɛkt ya to tu kategori.
| Sayd ifekt dɛm fɔ di C1 Inhibitor vaysin | |
|---|---|
| Siriɔs sayd ɛfɛkt dɛm we yu fɔ ripɔt to yu dɔktɔ ɔ ETU wantɛm wantɛm | |
| Siriɔs alɛji dɛn | Skin rash, it, swel na yu fes, lip ɔ tong, i nɔ izi fɔ blo. |
| Di sayn dɛn we de sho se blɔd de klɔt | Pen, swel ɛn wam na yu leg (DVT), at fɔ blo, pen na yu chɛst. |
| Di sayn dɛn we pɔsin kin gɛt we i gɛt Strɔk | Wantɛm we yu fes, yu an, ɔ yu fut kin wik, yu kin kɔnfyus, yu nɔ kin ebul fɔ tɔk ɔ ɔndastand, yu nɔ kin ebul fɔ waka, yu ed kin tɔn, yu nɔ kin balans. |
| Ɔda siriɔs sayn dɛn | Siriv ed pen, vishɔn chenj. |
| Sayd ɛfɛkt dɛn we nɔ kin siriɔs, bɔt dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Ed de at | Dis na wan kɔmɔn sayd ɛfɛkt. |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, duya tɛl yu dɔktɔ bɔt dɛn bak.
Sɔm ɔda tin dɛn we wi fɔ tink bɔt
- Ɔvados: If yu tink se yu dɔn ɔvados pan ɛni mɛrɛsin, kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta wantɛm wantɛm na di Kolombo Nashɔnal Ospital , ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
- If yu mis wan doz: If yu mis wan doz, tek am as yu mɛmba. Bɔt if i dɔn lɛf smɔl fɔ lɛ yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos di sem tɛm.
- Dɛn mek am wit mɔtalman blɔd: As wi bin dɔn tɔk, na mɔtalman blɔd dɛn mek dis mɛrɛsin. So, na rili smɔl, bɔt nɔto ziro, risk de fɔ transmit infɛkshɔn. Bɔt dɛn kin mek dis mɛrɛsin afta dɛn dɔn rili strikt fɔ klin ɛn tɛst am. Sote naw, dɛn nɔ ripɔt ɛni infekshɔn. Tɔk to yu dɔktɔ bɔt ɛni kwɛstyɔn we yu go gɛt bɔt dis.
- Nɔ sheb di mɛrɛsin wit ɔda pipul dɛn: Dɛn dɔn gi dis mɛrɛsin fɔ yu nɔmɔ. Nɔ ɛva sheb am wit ɔda pipul dɛn.
I rili impɔtant bak fɔ mek yu dɔktɔ no if yu sik nɔr de bɛtɛ, ɔr if dɛn de wɔs.
Mɛsej we dɛn kin kɛr go na os
- C1 Inhibitor na spɛshal vaysin we dɛn kin gi fɔ mek i nɔ swel wantɛm wantɛm we Angioedema kin mek.
- Bifo yu tek dis mɛrɛsin, tɛl yu dɔktɔ bɔt ɔl yu wɛlbɔdi infɔmeshɔn, mɔ di prɔblɛm dɛn we de mek yu blɔd klɔt ɛn alɛji.
- We yu de yuz di mɛrɛsin, no bɔt siriɔs sayd ɛfɛkt dɛn (especially sayn dɛm fɔ blɔd klot ɔ strok). If yu gɛt ɛni wan pan dɛn tin ya, go to dɔktɔ wantɛm wantɛm.
- Tɔk opin wan wit yu dɔktɔ bɔt ɛni kwɛstyɔn ɔ wɔri we yu gɛt bɔt dis mɛrɛsin. Nɔ fred.
- If yu de yuz sirinj na os, mek shɔ se yu trowe am fayn ɛn sef wan.
👩🏽 ⚕️ Ɔda kwɛstyɔn dɛn (FAQ dɛn)
💬 Wetin dɛn kin yuz Difenoxin ɛn Atropine / Motofen tablɛt fɔ?
Dis nɔto mɛrɛsin we yu kin jɔs bay na famasi! Dis na wan kɔmbaynshɔn fɔ di mɛrɛsin dɛn we rili pawaful we de insay wan klas ɔf drɔgs (Opioid antidiarrheal) we dɔktɔ dɛn kin gi fɔ stɔp bad bad dayarɛa ɔ vɔmit wantɛm wantɛm we nɔ kin bia ɛn we kin kɔntinyu ɛn lɛk wata!
💬 We bad bad dayarɛa kam, aw dis pil (Motofen) go stɔp di dayarɛa wantɛm wantɛm?
We yu gɛt bɔdi, di insay de muv kwik kwik wan ɛn push di stɔl kɔmɔt. di opioid mεdisin (Difenoxin) we de insay dis mεdisin de paralayz di mכsul dεm na di intestines bay 100% εn i de slo dכn (Decreases GI motility). Dɔn, we di stɔl de na di intestinal, i kin absɔb wata fayn fayn wan ɛn dayarɛa kin stɔp wantɛm wantɛm. Atropine (Anticholinergic) de ɛp bak fɔ dray di saliva/likwid flɔ frɔm di intestinal.
💬 Wetin mek smɔl atropine de na dis antidiarrheal pill? Wetin na di denja dɛn?
Di ‘Difenoxin’ we de insay dis na drɔg lɛk Opioid! So, if yu drink bɔku pan dis, yu kin rili ‘drunk/high’. Fɔ mek dat nɔ apin, dɛn ad ‘Atropine’ as pɔnishmɛnt fɔ di wan dɛn we de drink dɛn tin ya sikrit wan! If yu drink bɔku pils, dis Atropine kin mek yu mɔt dray bad bad wan, yu at kin bit kwik kwik wan, ɛn yu kin gɛt urinary retention (Anticholinergic toxicity). Dɔn bak, if dɛn gi pikin dɛn, dɛn kin stɔp fɔ blo (Respiratory depression) ɛn ivin day!
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