Yu bɔdi de big ɛn yu fes de rawnd lɛk ful mun? Lɛ wi tɔk bɔt ‘Cushing’s Syndrome’!

Yu dɔn notis dis biɛn tɛm se yu bɔdi shep dɔn chenj smɔl, mɔ rawnd yu ɔpa bɔdi ɛn bɛlɛ, ɛn yu fes dɔn rawnd lɛk ful mun? Sɔntɛm yu gɛt smɔl smɔl fat we de gro na di bak pat na yu nɛk. Dis nɔto jɔs random tin dɛn. Bihayn dɛn sayn ya kin gɛt wan ɔmon sik we dɛn kɔl Cushing’s Syndrome . Nɔr wɔri, dis na sik wae kin mɛn bɔrku tɛm. Lɛ wi tɔk bɔt dis simpul wan, di we we ɔlman go ɔndastand.

Fɔ tɔk am simpul wan, wetin na di sik we dɛn kɔl Cushing’s Syndrome?

Cushing’s Syndrome, ɔ hypercortisolism , na wan sik we kin apin we wi bɔdi de mek tumɔs pan di ɔmon we dɛn kɔl cortisol . Naw yu go de wɔnda wetin na kɔtisol. Kɔtisol na wan rili impɔtant ɔmon we tu smɔl smɔl gland dɛn we de ɔp wi kidni dɛn, we na di adrenal gland dɛn, de mek. I de du bɔku wok na wi bɔdi.

• I de kɔntrol blɔd prɛshɔn .
• I de rigul di blɔd shuga lɛvɛl .
• I de ridyus di inflamɛns na di bɔdi.
• I de ɛp fɔ chenj di it we wi de it to ɛnaji.

Imajin, ɔl dis kin apin we di kɔtisol jɔs de. Bɔt we dis ɔmon tu bɔku, di wok we ɔda sistɛm dɛn na di bɔdi de du kin bigin fɔ go haywire. Na dat wi kin kɔl Cushing’s Syndrome. Dis sik kin kam pan uman dɛm pas man dɛm. I kin mɔna pipul dɛn we ol bitwin 25 ɛn 40 ia.

Wetin na de men tin wae kin mek pɔrsin gɛt dis sik wae de mɛk pɔrsin gɛt dis sik?

Bɔku rizin dɛn kin de fɔ dis. Lɛ wi luk di men wan dɛn.

1. Yuz mεdikeshכn (mכst kכmכn kכz) .

Di tin we kin mek pɔsin gɛt dis sik na we dɛn kin yuz bɔku mɛrɛsin dɛn we dɛn kɔl glukɔkɔtikoyd fɔ lɔng tɛm . Dɛn kin kɔl dɛn tin ya kɔtikosterɔyd ɔ jɔs stɛroyd . Fɔ ɛgzampul, prɛdnisonYu kin tek di mɛrɛsin we dɛn kɔl. Dɔktɔ dɛn kin se dɛn fɔ tek dɛn mɛrɛsin ya fɔ sik dɛn lɛk asma, rεumatoid at, lupus, ɔ afta dɛn dɔn transplant dɛn ɔgan dɛn. Dis na rili pawaful drɔgs we de kɔntrol inflamɛns. Bɔt we dɛn yuz dɛn tin ya fɔ lɔng tɛm, Cushing’s Syndrome kin apin as sayd ɛfɛkt. כlso, dis kכndyushכn kin apin bikoz fכ kכntinyu fכ injεkshכn stεroyd fכ tin dεm lεk jכyn pen εn bak pen. Dis kɔndishɔn nɔ kin bɔku bikɔs ɔf di stɛroyd krim dɛn we dɛn kin yuz fɔ sik dɛn na di skin, bɔt i kin apin.

2. Tumɔs we kin apin na di bɔdi

di kכtisol lεvεl kin inkrεs bak insay wi bכdi. di rizin fכ dis na difrεn kayn tכmכro dεm we de divεlכp na di bכdi.

• Pituitary Tumors: If smɔl tumor de divɛlɔp na di pituitary gland we de na di bays pan wi bren , i kin bigin fɔ mek mɔ ɔmon we dɛn kɔl ACTH (Adrenocorticotropic hormone) . dis ACTH כmon na in de gi signal fכ di adrenal gland dεm fכ prodyuz kכtisol . So we ACTH de inkrεs, di kכtisol prodakshכn de inkrεs bak כtomatכk. Wi kin kɔl dis sik bak Cushing’s Disease .
• Adrenal Tumors: Sɔntɛnde, tumor kin divɛlɔp pan di adrenal gland insɛf, we kin mek di kɔtisol we pasmak dairekt wan.
• Ectopic Tumors: Na sכm tεm we tכmכro kin divεlכp na ples we ACTH כmon nכ de prodyuz, lεk di lכng , pankrias , כ tayroyd gland , εn bigin fכ mek ACTH.

Dɛn tumbu ya kin bi kansa ɔ nɔ kin gɛt kansa.

Wetin na di sayn dɛm fɔ dis sik?

De sik kin difrɛn frɔm pɔrsin to ɔda pɔrsin, bɔt sɔm kɔmɔn sayn dɛm de wae yu kin si wae de sik dɔn go bifo. Lɛ wi luk dɛn tin ya na wan tebul. Apat frɔm dat, sɔm pipul dɛn kin notis pepul ɔ pink strɛch mak na dɛn bɛlɛ, shɔl, an, ɛn chɛst. As di bon dɛn de wik, dɛn kin gɛt bak pen ɔ dɛn rib dɛn kin brok, nɔto jɔs we dɛn bɛn ɔp, es wet, bɔt bak we dɛn grap frɔm chia. If yɔŋ pikin dɛn gɛt dis sik, dɛn go de gro sloslo , ɛn dɛn kin fat bak.

Aw di dɔktɔ kin no bɔt dis sik?

I kin tek sɔm visit fɔ yu dɔktɔ fɔ kɔnfirm di diagnosis. Fɔs, i go chɛk yu bɔdi ɛn aks yu sɔm kwɛstyɔn dɛn.

• Wetin na yu sayn dɛm?
• Ustɛm yu bin si dɛn tin ya fɔ di fɔstɛm?
• Us mɛrɛsin yu de tek? (Ɛspɛshali stɛroyd dɛn)
• Yu kin fil se yu de chenj yu maynd?

Bay dis infɔmeshɔn, if dɛn tink se gɛt Cushing’s Syndrome, di dɔktɔ go tɛl yu fɔ du sɔm tɛst dɛn.

• 24 awa urinary fri kכtisol tεst: I de mכsu di lεvεl fכ kכtisol na di urine we dεn kכlekt ova 24 awa.
• Dexamethasone suppression test: Dɛn kin gi wan smɔl doz stɛroyd pil arawnd 11 p.m., ɛn dɛn kin du blɔd tɛst di nɛks mɔnin fɔ si ɔmɔs kɔtisol di bɔdi stil de mek.
• let-nayt saliva kכtisol lεvεl: I de mכsu di kכtisol lεvεl na wan saliva sεmpl we dεn tek na nɛt.

If dɛn tɛst ya sho se yu gɛt Cushing’s Syndrome, di nɛks tin we yu fɔ du na fɔ fɛn di tin we mek yu gɛt dis sik . Fɔ du dis, spɛshal dɔktɔ kin du sɔm ɔda tɛst dɛn. Fɔ ɛgzampul, blɔd tɛst fɔ chɛk di ACTH ɔmon lɛvɛl, CT ɔ MRI skan.

Wetin na di tritmɛnt dɛm fɔ dis?

Di we aw dɛn de trit yu kin dipen pan wetin de mek yu gɛt dis sik.

• • If di kɔz na sterɔyd mɛrɛsin: Yu dɔktɔ go bigin fɔ ridyus yu stɛroyd doz smɔl smɔl as dɛn de kɔntrol yu ɔda mɛrɛsin (e.g. asma, at at).

Di tin we impɔtant pas ɔl: Nɔ stɔp fɔ tek stɛroyd wantɛm wantɛm if yu dɔktɔ nɔ advays yu. If yu du dat, dat kin mek yu gɛt siriɔs sayd ɛfɛkt.

• If di tin we mek i kam na di tumbu: Dɛn kin nid fɔ du ɔpreshɔn fɔ pul di tumbu. Sɔntɛnde, dɛn kin gi dɛn redyushɔn tɛrapi apat frɔm di ɔpreshɔn.
• Ɔda tritmɛnt dɛn: If ɔpreshɔn ɔ redyushɔn tɛrapi nɔ wok, dɛn kin gi mɛrɛsin fɔ kɔntrol di we aw dɛn de mek kɔtisol. Bɔt dɛn mɛrɛsin ya kin gɛt bad bad tin dɛn bak, so dɛn fɔ tek dɛn ɔnda dɔktɔ in sɔpɔtishɔn.

Aw fɔ chenj layf ɛn it wit tritmɛnt?

We yu de du tritmɛnt, fɔ ajɔst yu layf ɛn it kin ɛp yu bad bad wan fɔ kɔntrol yu sik dɛn.

• It gud it:
• It it wae gɛt bɔku kalsiɔm ɛn vaytamɛn D. Dis sik kin mek yu bon dɛn wik. Milk, yogɔt, chiz, grɛn vɛjitebul, ɛn smɔl fish (we gɛt bon) fayn.
• Limit it dɛn we gɛt bɔku sodium ɛn ɔyl/fat . Dɛn tin ya kin mek yu gɛt ay blɔd prɛshɔn ɛn yu bɔdi kin gɛt mɔ wet.
• Kɔntrol di pen:Tin dɛn lɛk fɔ was wit ɔt, fɔ masaj am saful saful, ɛn fɔ du wata aerobiks kin ɛp fɔ mek yu nɔ gɛt pen na yu mɔsul dɛn.
• Mental hεlth: Dis sik kin mek yu nɔr gɛt bɛtɛ trɛnk igen. Tɔk to yu fambul ɛn padi dɛn bɔt dis. Aks fɔ dɛn sɔpɔt. If nid de, aks pɔsin we de advays yu fɔ ɛp yu. Yu kin aks yu dɔktɔ fɔ gayd yu.

Cushing’s Syndrome, kɔtisol, stɛroyd, ɔmon, ay blɔd prɛshɔn, dayabitis, bɔdi atrofi, mun fes, bɔfalo hump, pituitary gland, adrenal gland, Cushing’s syndrome simptom dɛm, Cushing’s syndrome tritmɛnt