Yu de it wit wan strenj ples na yu skin? I kin bi di sik we dɛn kɔl Extramammary Paget’s Disease (EMPD)!

Yu dɔn ɛva notis wan pat pan yu skin we gɛt rɛd, skel, ɛn sɔntɛnde i kin krɔs, mɔ na yu smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl smɔl. I tan lɛk se i de gro smɔl smɔl, ɛn sɔntɛnde i kin it, nɔto so? Okay, so tide wi go tok boht wan speshal skin kondishon lek dat. Dɔktɔ dɛn kin kɔl am Extramammary Paget’s Disease , ɔ EMPD fɔ shɔt tɛm. I nɔ kin apin smɔl, bɔt i impɔtant fɔ no bɔt.

Wetin na di sik we dɛn kɔl Extramammary Paget’s Disease (EMPD)?

Fɔ tɔk am simpul wan, EMPD na wan sik we nɔ kin apin na di skin. Sɔntɛnde, i kin gɛt fɔ du wit ɔda kayn kansa. Bɔt nɔto so i kin bi ɔltɛm. Na wan sik wae yu skin kin rεd, skel, כ krεse εn de gro big. Sɔmtɛm, dɛn nɔr kin no bɔt am fɔ lɔng lɔng tɛm afta di sik bigin.

Dɛn gi am di nem "Paget's Disease" afta Sir James Paget, we na bin wan briliant British dɔktɔ we bin de insay di ia 1900. Dɛn dɔn yuz in nem fɔ sɔm ɔda kayn kansa dɛn bikɔs ɔf di tin dɛn we i dɔn du fɔ di wok we dɛn de du fɔ mɛn sik dɛn. di wכd "ekstramammary" min "ausayd di brεst." Dis nɔ fɔ kɔnfyus wit di sik we Pejɛt gɛt na di bɔdi.

Dɛn se bitwin 7% ɛn 40% pan di pipul dɛm wae gɛt Extramammary Paget’s Disease kin gɛt wan ɔndalayn kansa . Bɔt, lɛk aw a bin dɔn tɔk, EMPD nɔ kin bi sayn fɔ ɔda sik ɔltɛm. If yu trit yu kwik kwik wan, dat kin ɛp fɔ ridyus yu sik ɛn ɛp fɔ no di kansa we de ɔnda yu.

Wetin na di men kayn EMPD dɛn?

Tu men kayn EMPD dɛn de:

1. Praymari EMPD: Dis na wan sik we de apin na di skin we de apin bay insɛf. I kin bigin pan di skin we nɔ gɛt ɛni ɔda rizin.

2. Sεkɔndari EMPD: Dis kin kam bikɔs ɔf wan ɔndalayn kansa ɔdasay na di bɔdi.

Udat kin gɛt mɔ chans fɔ gɛt EMPD?

Ɛnibɔdi kin gɛt EMPD, bɔt i kin bɔku pan dɛn grup ya:

• Pipul dɛn we ol bitwin 50 ɛn 80 ia .
• Kɔmɔn fɔ uman dɛn .
• Yu kin si am bak bitwin man dɛn na Eshia .
• Wait pipul dɛn.

Bɔt i impɔtant fɔ mɛmba se dis na tin we nɔ kin apin so ɔltɛm.

Wetin mek dis EMPD kin apin?

Wetin kin mek pɔsin gɛt praymari EMPD?

Fɔ tɔk tru, dɔktɔ dɛn stil nɔ no bɛtɛ bɛtɛ wan wetin kin mek pɔsin gɛt praymari EMPD. Dɛn kin tink se i kin bigin na sɔm kayn sɛl dɛn na wi bɔdi. Dɛn kayn sɛl ya na:

• di apokrin gland dakt sεl dεm: Dis na swet gland dεm εn dεn de nia di ia fכlikul dεm.
• di kεratinosayt stεm sεl dεm: Dis na sεl dεm we de εp fכ mek di skin fayn.
• di tכk sεl dεm: dis na sεl dεm we de fכnshכn na di skin (`vulvar tissue`) we de rawnd di nipl εn di vagina opin.

Wetin kin mek sɛkɔndari EMPD?

Sɛkɔndari EMPD na kansa ɔdasay na di bɔdi. Dɛn se na di rɛktal kansa na in de mek lɛk wan pat pan tri pan di wan dɛn we gɛt EMPD. Apat frɔm dat, ɔda kayn kansa de we kin mek pɔsin gɛt sɛkɔndari EMPD:

• Kansa na di anal
• Blada kansa
• Kansa na di sɛvikal
• Kansa na ovarian
• Prɔstat kansa
• Kansa na di uterin

Wetin na di sayn dɛm fɔ EMPD?

Di men sayn fɔ EMPD na wan skin rash we tan lɛk ɛkzema . Risach dɔn sho se pan lɛk 65% pan di wan dɛn we gɛt EMPD, i kin apin rawnd di vulva , ɛn na lɛk 20%, i kin apin rawnd di anus .

Yu kin si say dɛn na yu skin we gɛt dɛn kayn tin ya:

• Lɛk wan krɔkrɔs (`Krɔsti`) .
• I dɔn tɔn rɛd (`Rɛd`) .
• Skayl we dɛn kɔl

di spat dεm de big sכmtεm, εn kin gεt ed dεm we nכ de rεgulεr. As EMPD de go bifo, dip ɔlsa ɔ nodul kin kam. Ɔda sayn dɛn we de sho se yu gɛt dis sik na:

• Fɔ mek yu fil lɛk se yu de bɔn
• Di skin kin rɛd ɛn i kin fil lɛk se i de vɛks .
• I de it
• I kin mek pɔsin fil pen ɔ i kin tan lɛk
• Skin we dɔn swel (ɛdima).

EMPD kin apin mכst na di εria dεm we yu swet gland dεm (especially di apocrine skin gland dεm) de. Dɛn kin si am mɔ rawnd di say we di vagina de opin. I kin apin bak na dɛn say ya:

• Arawnd di anus (`Anus`) .
• Penis we de na di bɔdi
• Pɛriniɔm
• Skrotum we dɛn kɔl Skrotum

Na smɔl tɛm nɔmɔ, dɛn kin si EMPD bak na ɔda pat dɛn na di bɔdi, lɛk:

• Di bɛlɛ we de na di bɛlɛ
• Armpit na di bɔdi
• Bɛlɛ bɔtin
• Bɔt dɛn
• Iya, aylid, fes ɔ skel
• Lɔwa chɛst
• Ni ɔ shɔl

I impɔtant fɔ no se lɛk 10% pan di pipul dɛm wae gɛt ɛkstra mamary Paget’s disease nɔr kin gɛt ɛni sayn .

Aw dɛn kin no dis EMPD kɔndishɔn?

Fɔs, dɔktɔ go aks yu bɔt di sayn dɛn we yu gɛt ɛn du ɛgzam fɔ yu bɔdi. If dɛn sɔspɛkt se yu gɛt EMPD, dɛn go:Dɛn kin du wan skin bayɔpsi. Bayopsi min fɔ tek smɔl sampul pan yu skin ɛn chɛk am ɔnda maykroskɔp.

we dεn de luk כnda maykroskכp, wan patכlayzm de luk fכ spεshal, big, abnכmal sεl dεm we dεn kכl "Paget sεl dεm." dεn kin no dεn sεl dεm ya bak bay we dεn de luk aw dεn de riak to difrεn kεmikכl dεm (immunohistochemistry).

Aw yu go no if yu gɛt kansa wit EMPD?

Afta dɛn dɔn no se yu gɛt EMPD, yu dɔktɔ go du sɔm ɔda tɛst fɔ chɛk if yu gɛt ɔndalayn kansa. Dɛn tɛst ya kin bi:

• Ultrasound skan (`Ɔltrasaund`) .
• Fɔ chɛk di bɔdi (mammogram) .
• Pap smear we dɛn kin yuz
• Kolonoskopi ɔ proktoskɔpi
• CT skan we dɛn kin du
• Sistoskɔpi (we dɛn de chɛk di blad) .
• Prɔstat ɛgzam
• Retrograde pyelogram (we dεn de egzamin di kidni dεm εn di urinary tract) .
• כltra saund כ nidul bayopsi fכ di limf no dεm
• כp εndoskopi (we dεn de egzamin di trot, di εsophagus, εn di bεlε) .

Wetin na di tritmɛnt dɛm fɔ EMPD?

Dɔktɔ dɛn kin trit di sik we dɛn kɔl Extramammary Paget’s disease wit ɔpreshɔn.

• Mohs ɔpreshɔn: Insay dis ɔpreshɔn, di ɔspitul kin pul di skin we afɛkt layt bay layt, ɛn dis kin kip di wɛlbɔdi skin we de rawnd am.
• Waid lokal excision: Insay dis prosidur, di sajin de pul di eria na EMPD wit sɔm hεlty tisu dεm we de rawnd am. Dɔn dɛn kin sutura di ed dɛn na di wund.

Sɔntɛnde, dɔktɔ dɛn we de du ɔpreshɔn kin gɛt fɔ pul bɔku say na di skin ɛn ɔda tin dɛn we de na di bɔdi. sכm pipul dεm we gεt EMPD rawnd di vulva kin nid fכ pul pat כ כl di vulva (a `vulvectomy`).

Tink bɔt dis: If yu nɔ ebul fɔ du ɔpreshɔn bikɔs ɔf ɔda wɛlbɔdi prɔblɛm ɔ yu nɔ gɛt bɛtɛ wɛlbɔdi, yu dɔktɔ kin tɛl yu ɔda tritmɛnt dɛn lɛk:

• Imyunotɛrapi
• Laser skin we de kɔmɔt bak
• Fɔtodaynamik tɛrapi (PDT) .
• Redyushɔn tɛrapi
• Di mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn kansa (cytotoxic drugs) .

Di tin we impɔtant pas ɔl na dat if kansa de we de ɔnda am, dɛn fɔ trit am sɛf sɛf.

We de fɔ ridyus di risk fɔ gɛt EMPD?

I sɔri fɔ no se natin nɔ de we wi go du fɔ ridyus di risk fɔ gɛt EMPD.

Us kayn fiuja pɔsin we gɛt EMPD kin ɛkspɛkt?

Afta yu dɔn gɛt tritmɛnt fɔ EMPD, yu go nid fɔ gɛt fɔlɔp visit wit yu dɔktɔ. Dis go dipen pan usay di EMPD bin de. I kɔmɔn fɔ mek EMPD kam bak na ɔ rawnd di sem eria usay dɛn bin dɔn trit am bifo. So, i rili impɔtant fɔ kɔntinyu fɔ fala wetin yu dɔktɔ tɛl yu fɔ du.

Extramammary Paget’s disease nɔ kin bɔku we i kin skata (metastasizes) to ɔda pat dɛn na di bɔdi. Bɔt sɔntɛnde i kin go na di limf no dɛn ɔ ɔda pat dɛn. Yu dɔktɔ kin ɛksplen fayn fayn wan wetin pɔsibul pan yu kes.

EMPD kin kam bak afta i dɔn wɛl?

Yes, EMPD na wan sik wae kin kam bak ivin afta tritmɛnt ɛn wɛl, ivin afta bɔrku ia. Sɔntɛnde, i kin kam bak afta pas 15 ia. Na dat mek dɔktɔ dɛn kin se dɛn fɔ de wach dɛn fɔ lɔng tɛm ɛn fɔ chɛk dɛn ɔltɛm.

If a gɛt EMPD, aw a go tek kia ɔf misɛf?

Di bɛst tin we yu kin du na fɔ kɔntinyu fɔ go to yu dɔktɔ fɔ mek yu go ebul fɔ fala yu ɔltɛm. If yu dɔktɔ si sayn dɛm fɔ EMPD de kam bak, dɛn kin bigin tritmɛnt wantɛm wantɛm.

Ustɛm a fɔ go to dɔktɔ?

If yu notis ɛni nyu sayn fɔ EMPD, ɔ if yu gɛt ɛni nyu sayn, go to dɔktɔ wantɛm wantɛm.

I nɔmal fɔ mek yu fred, shem, ɛn fil bad we yu notis se yu skin gɛt rɔsh ɔ lump na yu bɔdi we gɛt sɛnsitiv say lɛk yu bɔdi. Dis sik we dɛn kɔl Extramammary Paget’s Disease (EMPD), sɔmtɛm dɛn kin kɔnfyus am wit ɔda sik dɛn na di skin, so i kin tek sɔm tɛm fɔ mek dɛn no di sik kɔrɛkt wan. If ɔndalayn kansa de, EMPD kin rili siriɔs.

Bɔt di gud nyus na dat bɔku pipul dɛn we gɛt EMPD de liv nɔmal, ful layf afta dɛn dɔn gɛt tritmɛnt. Dɛn kin trit EMPD wit ɔpreshɔn. If kansa de we de ɔnda am, dat bak go nid fɔ trit. Bikɔs di sik we dɛn kɔl Extramammary Paget’s Disease kin kam bak, we yu de chɛk yu dɔktɔ ɔltɛm, dat kin ɛp fɔ no am kwik if i kam bak.

Di tin dɛn we impɔtant pas ɔl fɔ mek yu mɛmba (Take-Home Message) .

• EMPD na wan sik wae nɔr kin apin na di skin wae kin gɛt fɔ du wit kansa.
• Pe atɛnshɔn to ɛni pat pan di skin we rɛd, we gɛt skel, we gɛt krɔs, ɔ we rayz, mɔ we de rawnd di bɔdi, di an, ɔ di an. Di sayn dɛm kin bi fɔ it, bɔn, ɛn pen.
• If yu si sayn lɛk dis , nɔ shem ɔ fred, bɔt go to dɔktɔ wantɛm wantɛm.
• Dɛn kin no EMPD wit wan skin bayɔpsi.
• Ɔpreshɔn na di tritmɛnt we dɛn kin yuz mɔ.
• I impɔtant fɔ kɔntinyu fɔ chɛk di mɛrɛsin, bikɔs EMPD kin kam bak.
• Nɔ wɔri, bɔrku pipul dɛm wae gɛt EMPD kin liv fayn afta tritmɛnt. Di men tin na fɔ no di sik kwik kwik wan ɛn gɛt di rayt tritmɛnt.

If yu gɛt ɛni ɔda kwɛstyɔn bɔt dis, tɔk to yu dɔktɔ. I kin gi yu advays we rayt fɔ yu.

` Ekstramammary Paget’s Disease, EMPD, skin sik, skin kansa, Paget sel, skin spat, it, vulva, perianal eria, skin sik, Mohs ɔpreshɔn