Yu bɛlɛ we de at nɔto jɔs na yu bɛlɛ bɔg? Lɛ wi tɔk bɔt GIST (Gastrointestinal Stromal Tumor)!

Sɔntɛnde, yu bɛlɛ kin pwɛl bak, ɔ yu bɛlɛ kin at, ɔ yu kin fil se yu gɛt ebi? Sɔntɛnde wi kin tink se it bad, "gastric upset", ɔ jɔs "flatulence". Bɔt, tink bɔt am, sɔmtɛm, wan mɔr siriɔs stori kin de biɛn dɛn kayn smɔl smɔl sik ya. Wan pan dɛn kayn tin ya, we nɔ kin so, bɔt we rili impɔtant fɔ no bɔt kansa kɔndishɔn na GIST, we tinap fɔ Gastrointestinal Stromal Tumor . Lɛ wi tɔk bɔt dis smɔl mɔ, bɔt rili simpul, i fayn?

Wetin na dis gastrointestinal stromal tumor (GIST)?

Fɔ tɔk am simpul wan, GIST na kansa tumbu dɛn we de fɔm na di wɔl dɛn na yu dijestiv trakt —di pat na yu bɔdi usay it ɛn drink de travul frɔm yu mɔt to yu bɛlɛ ɛn afta dat tru yu intestinal fɔ mek dɛn digest. Dɛn tumbu ya, fɔ tɔk di kɔrɛkt tin, kin fɔdɔm insay wetin dɔktɔ dɛn kɔl ‘ sɔft tisu sarkoma.’

Naw tink bɔt am, sɔm GIST tumbu dɛn rili smɔl, lɛk pensil iras ɔ pia. If na rili smɔl tumbu, yu nɔ kin ivin notis am ɔ fil ɛni pen. Bɔt sɔm tumbu dɛn kin bigin fɔ gro as tɛm de go. Na da tɛm de dɛn GIST ya kin bigin fɔ mek yu gɛt difrɛn kayn sik ɛn ɔda wɛl bɔdi prɔblɛm. Bɔku tɛm, dɔktɔ dɛn kin trit dis GIST kɔndishɔn bay we dɛn kin du ɔpreshɔn fɔ pul di tumbu ɔ di tumbu dɛn kpatakpata.

Aw kɔmɔn dis sik we dɛn kɔl GIST?

Infakt, GIST na wan kayn kansa we nɔ kin bɔku . Ivin we yu kɔmpia am to ɔda kɔntri dɛn na di wɔl, na di sem tin. Fɔ ɛgzampul, na kɔntri lɛk Amɛrika, na 4,000 to 6,000 nyu pipul dɛn nɔmɔ kin gɛt GIST ɛvri ia. So yu kin imajin aw dis sik nɔ kin apin so ɔltɛm. Na dat mek i impɔtant fɔ no bɔt am, so dat if yu gɛt sɔm kayn sik, yu go go to dɔktɔ kwik kwik wan.

Wetin na di sayn dɛm fɔ GIST?

As wi bin dɔn tɔk, if di GIST tumbu dɛn rili smɔl, yu nɔ go gɛt ɛni sayn. Bɔku tɛm, dɛn kin no GIST tumbu bay we dɛn de du tɛst, lɛk we dɛn de skan bɛlɛ, ɔ we dɛn de du ɔda ɔpreshɔn.

Bɔt as di lump de big, ɔ dipen pan usay i de, sɔm sayn dɛn kin sho. Dɛn tin ya na di sayn dɛm wae kin kam pan pɔrsin:

• Fɔ fil se yu bɛlɛ de at ɔ yu nɔ de fil fayn . Dis kin jɔs bi fɔ fil se yu ful-ɔp ɔ sɔntin we stɔp na yu bɛlɛ.
• Blɔd na yu stɔl ɔ yu stɔl we gɛt blɔd. Sɔntɛnde di stɔl kin dak blak, we na sayn bak fɔ blɔd insay.
• Kɔnstipɛshɔn min se yu nɔ go gɛt bɔdi fɔ sɔm dez.
• ƆltɛmFɔ fil se yu taya bad bad wan ɛn yu taya . I tan lɛk se layf nɔ de na di bɔdi.
• Fɔ lɔs yu wet we yu nɔ tray.
• Anorexia min se yu nɔ want fɔ it.
• We yu de vɔmit blɔd . Dis na sayn we rili siriɔs.

If yu dɔn de gɛt wan ɔ mɔ pan dɛn sik ya fɔ sɔm tɛm, i go fayn fɔ mek yu go to dɔktɔ ɛn chɛk yu, pas fɔ jɔs de wɔnda se, "Wetin na dat?"

Wetin na di tin dɛn we kin mek pɔsin gɛt GIST?

Bɔku tɛm, GIST kin kam we chenj ɔ muteshon de na wan jin we dɛn kɔl KIT na wi bɔdi. tink bɔt am dis KIT jin tan lɛk smɔl mɛsenja we de tɛl sɔm sɛl dɛn na wi dijestiv sistɛm fɔ "divayd ɛn bɔku." So, we wan prɔblɛm de na dis jin, dɛn sɛl dɛn de kin bigin fɔ sheb ɛn bɔku tumɔs kwik kwik wan ɛn dɛn nɔ kin ebul fɔ kɔntrol dɛn. Dat lump, ɔ GIST, kin mek we dɛn sɛl dɛn de gro we dɛn nɔ ebul fɔ kɔntrol. Dis jin mכtεshכn kin apin afta wi bכn, insay wi layf. I nɔto sɔntin we mama ɛn papa gɛt frɔm in pikin dɛn.

dis KIT jin de tεl di sεl dεm fכ mek wan protin we dεn kכl KIT CD117 . dis protin de mek di sεl dεm na di dijestiv sistεm divεlכp. insay GIST, dis prכsεs de go awry, we de mek tכmכro dεm fכm.

Bɔt pan ɔl we i nɔ kin apin so ɔltɛm, sɔm tin dɛn we pɔsin kin gɛt frɔm in mama ɛn papa kin mek pɔsin gɛt GIST smɔl. Sɔm pan dɛn tin ya na:

• Famili GIST sindrom: Dis nɔ kin apin so ɔltɛm. wetin de apin ya na dat wan difεkt na di KIT jin de kכmכt frכm mama εn papa to pikin dεm. If dis apin, di risk fɔ gɛt GIST kin bɔku. כlso, GIST kin divεlכp we i yכng pas aw i kin bi εn mכr dan wan tכmכro kin divεlכp.
• Nyurofibromatosis tayp 1: Dis na jεnεtik sik bak. I kin mek sɔm kayn sɛl dɛn gro we dɛn nɔ ebul fɔ kɔntrol ɛn mek tumbu dɛn na difrɛn pat dɛn na di bɔdi. GIST na wan kayn tumbu we kin divɛlɔp dis we.
• Carney-Stratakis syndrome: Dis na sik bak we nɔ kin apin so ɔltɛm, we pɔsin kin gɛt frɔm in mama ɛn papa. Pipul wae gɛt dis sik kin gɛt bɔrku risk bak fɔ gɛt GIST pas ɔda pipul dɛm.

Aw dɛn kin no bɔt GIST?

We yu go to dɔktɔ we gɛt di sik dɛn we wi dɔn tɔk bɔt, i go aks yu fɔs bɔt di sik dɛn we yu gɛt, aw lɔng dɛn dɔn de, dɔn i go chɛk yu bɔdi . Dis min tin dɛm lɛk fɔ fil yu bɛlɛ.

Apat frɔm dat, yu dɔktɔ kin ɔda fɔ du sɔm ɔda tɛst fɔ no if yu gɛt GIST, in saiz, ɛn if i dɔn skata. Di men wan dɛn na:

• Ɛndoskopi we de ɔp: .Dis min se yu fɔ put wan tiub wit smɔl kamɛra tru yu mɔt ɛn chɛk di insay pat na yu trot, di it we yu de it (fud paip), ɛn di bɛlɛ. Dis kin mek yu ebul fɔ si dairekt if ɛnitin de, lɛk wan lump.
• CT scan: Dis kin yuz X-ray fɔ tek ditayla pikchɔ dɛn fɔ di insay pat pan yu bɛlɛ. Dis kin ɛp fɔ no di sayz ɛn usay di lump de.
• Positron emission tomography (PET) skan: Dis na spɛshal kayn skan bak. I de ɛp fɔ no aw di kansa sɛl dɛn de wok ɛn if dɛn dɔn spre to ɔda pat dɛn na di bɔdi.
• Bayopsi: Dis na di tɛst we dɛn kin yuz fɔ kɔnfɔm if yu gɛt GIST. Dis min se dɛn kin tek wan rili smɔl tisu frɔm di lump ɛn mek wan dɔktɔ we de stɔdi bɔt sik dɛn chɛk am ɔnda maykroskɔp . Dis go ɛp fɔ no if na GIST ɔ ɔda tin. sכmtεm dεn kin du di bayopsi di sem tεm we dεn de du di εndoskopi.

Aw dɛn kin trit GIST?

Di men pɔsin we de trit GIST na ɔnkɔlɔjis . Dɛn kin trit GIST wit ɔpreshɔn fɔ pul di tumbu. Bɔt di kayn tritmɛnt we go fayn fɔ yu go dipen pan wetin di tɛst dɛn go fɛn. Dis min se dɔktɔ dɛn go luk tin dɛn lɛk di sayz fɔ di tumbu, usay i de, ɛn if i dɔn skata (mɛtastas) frɔm usay i fɔs bigin.

Fɔ ɛgzampul:

• If di lump rili smɔl, yu ɔnkɔlɔji ɔpreshɔn kin ebul fɔ pul am kpatakpata wit ɔpreshɔn. Dɔn, dɛn nɔ go nid ɔda tritmɛnt.
• Bɔt if di tumbu rili big ɔ i de na say we at fɔ ɔpreshɔn, yu dɔktɔ we de mɛn yu kansa kin disayd fɔ gi yu wan kayn mɛrɛsin we dɛn kɔl targeted therapy fɔ mek di tumbu smɔl bifo dɛn du yu ɔpreshɔn. Dɛn mɛrɛsin ya de tɔch ɛn atak sɔm patikyula tin dɛn we de ɛp di GIST sɛl dɛn fɔ gro. Dis kin mek di tumbu smɔl ɛn mek i izi fɔ ɔpreshɔn pan am. Sɔntɛnde, dɛn kin kɔntinyu fɔ du dɛn tritmɛnt ya we dɛn dɔn tayt afta dɛn dɔn du di ɔpreshɔn fɔ stɔp GIST fɔ kam bak.

Mɛmba se nɔto ɔl GIST pasɛnt dɛn kin gɛt di sem tritmɛnt. Yu mɛdikal tim go tɔk to yu bɔt di bɛst tritmɛnt plan fɔ yu sityueshɔn.

Wetin na di sayd ɛfɛkt dɛm we di tritmɛnt kin gɛt?

Jɔs lɛk ɛni ɔda mɛrɛsin, GIST tritmɛnt kin mek sɔm sayd ɛfɛkt dɛn.

Sɔm sayd ɛfɛkt dɛm wae kin kam wae pɔrsin gɛt targeted therapy:

• Obstrukshɔn
• Dayarɛa (bɛlɛ de at) .
• Taya ɛn taya
• Mɔsul dɛn we kin kramp
• Nɔs (fɔ fil lɛk se yu de vɔmit) .

Kɔmɔn sayd ɛfɛkt dɛn we kin apin we dɛn de du ɔpreshɔn:

• Riakshɔn to anestezi (e.g., diziz, vɔmit) .
• Pen na di say we dɛn de du di ɔpreshɔn
• Blɔd we de kɔmɔt

Dɛn sayd ɛfɛkt ya nɔ kin apin to ɔlman di sem we. Sɔm pipul dɛn kin gɛt sɔm pan dɛn, ɛn ɔda wan dɛn nɔ kin gɛt ɛni wan pan dɛn. If yu fil ɛnitin we nɔ fayn, mek shɔ se yu tɛl yu dɔktɔ ɔ nɔs. Bɔku pan di sayd ɛfɛkt dɛn kin bi.

Wetin a fɔ ɛkspɛkt nɛks if a gɛt GIST?

Ivin afta di tritmɛnt dɔn, yu dɔktɔ we de mɛn yu kansa go kɔntinyu fɔ wach yu. Dis min se dɛn go aks yu fɔ kam insay fɔ fala-ap apɔntinmɛnt ɔltɛm fɔ chɛk if yu wɛl ɛn yu jenɛral wɛlbɔdi. Bɔku tɛm, dɛn apɔntinmɛnt ya kin apin ɛvri tri to siks mɔnt.

Insay dɛn visit ya, yu dɔktɔ go aks yu bɔt yu sik, ɛgzamin yu, ɛn i kin du ɔda tɛst dɛn bak, lɛk fɔ skan, fɔ si if di GIST dɔn kam bak ɔ aw i de ansa to tritmɛnt. Di tɛst dɛn we dɛn kin du na:

• CT skan fɔ di liva ɛn di bɔdi.
• MRI skan (Magnetic resonance imaging (MRI) skan) .
• PET skan fɔ si di rispɔns to di tritmɛnt dɛn we dɛn dɔn tɔk bɔt.

Yu dɔktɔ go disayd aw ɔltɛm yu fɔ du dɛn tɛst ya, i go dipen pan yu kɔndishɔn.

Wetin na di sɔvayv rit wit GIST?

Dis na sɔntin we rili impɔtant. Di rεt wae pɔrsin wae gɛt GIST kin liv kin difrɛn frɔm pɔrsin to ɔda pɔrsin. Bɔku tin dɛn de we kin mek pɔsin no dis. Fɔ ɛgzampul, di saiz fɔ di tumbu we dɛn no se i gɛt GIST, aw i de wok, yu ɔl wɛlbɔdi, ɛn aw di tumbu de ansa we dɛn gi yu tritmɛnt.

Akɔdin to di data we dɛn gɛda frɔm institiushɔn dɛm lɛk di US National Cancer Institute (NCI) , lɛk 85% pan di pipul dɛm wae gɛt GIST stil de alayv fayv ia afta dɛn dɔn no bɔt dis sik.

Bɔt we yu si sɔm statystik dɛn lɛk dis, yu fɔ mɛmba sɔm tin dɛn:

• Dis na jɔs ɛstimat: dɛn de bays pan di ɛkspiriɛns dɛm fɔ bɔku pipul dɛm wae dɔn gɛt GIST bifo. Di tin we de apin to yu kin rili difrɛn. Fɔ ɛgzampul, yu ej ɛn if yu gɛt ɔda mɛrɛsin kin afɛkt dɛn nɔmba ya.
• Dɛn nɔmba ya na istri: dɛn kin gɛda di data lɛk ɛvri fayv ia. So, di impak we di laytst tritmɛnt dɛn gɛt nɔ de insay dɛn nɔmba ya. If dɛn gɛt nyu tritmɛnt, dɛn nɔmba ya kin bɛtɛ mɔ ɛn mɔ.
• Di rεt wae yu de liv εn di layf εkspεktεshכn na tu difrεnt tin dεm: Di rεt wae yu de liv nכ de tεl yu aw lכng yu go liv. Layf ɛkspɛkteshɔn data kin at fɔ gɛt mɔ fɔ pipul dɛn we gɛt GIST.

So, nɔ mek yu at pwɛl wit dɛn nɔmba dɛn ya. If yu gɛt ɛni kwɛstyɔn, aks yu dɔktɔ we de mɛn kansa. I go ebul fɔ ɛksplen aw dɛn statystik ya de apin to yu sityueshɔn.

Aw yu de kia fɔ yusɛf?

Fɔ kia fɔ yu ɔl yu wɛl bɔdi na di bɛst tin we yu kin du fɔ yusɛf, ɔl tu di tɛm ɛn afta yu gɛt tritmɛnt fɔ GIST.

• It fayn: Tray fɔ it difrɛn it dɛn we gɛt bɔku prɔtin, we nɔ gɛt bɔku fat, ɛn we yu ebul fɔ it. Put grɛn, vɛjitebul, ɛn frut dɛn insay yu it ɛvride. If yu it di rayt tin, dat go mek yu bɔdi gɛt trɛnk fɔ mek i wɛl kwik kwik wan.
• Gɛt sɔm ɛksesaiz: We yu sik kin mek yu strɛs. Wae yu de wɛl frɔm tritmɛnt, layt ɛksɛsayz (lɛk fɔ waka) kin ɛp yu fɔ ridyus strɛs. Bɔt yu fɔ tɔk to yu dɔktɔ ɔltɛm bifo yu bigin fɔ du nyu ɛksɛsayz ɔ bifo yu bigin fɔ du ɛksɛsayz bak we yu bin dɔn de du.
• Nɔ smok ɔl: If yu yuz ɛni kayn tabak (inklud ilɛktronik sigrɛt) i kin mek yu gɛt nyu kansa, ɛn i kin mek yu gɛt GIST bak.

Wan sik lɛk GIST nɔ kin mek yu gɛt ɛni big big sayn fɔs. Ivin if yu du dat, yu go tink se na jɔs we yu nɔ de it fayn ɔ di bɛlɛ flu. So, fɔ no se yu gɛt wan rare kansa tumor lɛk dis kin bi big shɔk. If yu gɛt dis sik, tek sɔm tɛm fɔ tich yusɛf bɔt dis sik wae nɔr kin bɔrku ɛn aw yu kin trit yu. Bɔrku tɛm, tritmɛnt kin pul yu sik ɛn ivin mɛn GIST. Yu go gɛt bɔku kwɛstyɔn dɛn. Yu mɛdikal tim go de fɔ ansa dɛn ɔl ɛn sɔpɔt yu.

Fɔ dɔn, tin dɛn we wi fɔ mɛmba

Pan ɔl we GIST na sɔntin we yu fɔ fred, na sik we kin gɛt gud tin fɔ du if yu no bɔt am ɛn gɛt tritmɛnt insay di rayt tɛm.

• Nɔ ignore: If yu gɛt ɛni ɔda kayn pen na yu bɛlɛ we nɔ kɔmɔn, we nɔ de chenj, sayn dɛn we de sho se yu de blɔd, ɔ yu de lɔs yu wet we yu nɔ ɛksplen, go to dɔktɔ.
• Fɔ no di sik kɔrɛkt wan impɔtant: Dɛn nid spɛshal tɛst fɔ no if pɔsin gɛt GIST. So, aks fɔ spɛshal pɔsin fɔ tink bɔt dis.
• Tritmɛnt dɛn de: Tritmɛnt dɛn de we go wok fɔ GIST, lɛk ɔpreshɔn ɛn tritmɛnt we dɛn want.
• Nɔto yu wan de: yu mɛdikal tim, yu fambul, ɛn padi dɛn go ɛp yu fɔ du dis waka.

Di tin we impɔtant pas ɔl na fɔ kɔntinyu fɔ strɔng ɛn fala di advays dɛn we dɔktɔ gi yu.

` Gastrointestinal stromal tumor, GIST, kansa, dijestiv sistεm, KIT jin, כpεrayshכn, tεrapi we dεn tכk bכt