Hepatoblastoma: Yu no bɔt dis rare challenge to yu smɔl pikin in liva?

Mama ɛn papa, una kin tink bɔt una smɔl pikin in wɛlbɔdi ɔltɛm, nɔto so? Sɔntɛnde, ivin we yu bɛlɛ at smɔl ɔ yu nɔ want fɔ it, dat kin mek yu fred bad bad wan ɛn wɔri. Tide, wi go tɔk bɔt wan kansa we kin mek mama ɛn papa dɛn fred smɔl, bɔt fɔtunate wan, i nɔ kin apin so ɔltɛm . Dis na wetin dɔktɔ dɛn kin kɔl ɛpatoblastoma. Pan ɔl we di nem kin tan lɛk se i kɔmplikt smɔl, lɛ wi kip am simpul.

Wetin na ɛpatoblastoma? Lɛ wi ɔndastand am simpul wan.

Fɔ tɔk am simpul wan, ɛpatoblastoma na wan kayn kansa we nɔ kin apin na di liva . I kin mɔs afɛkt yɔŋ pikin dɛn we ol bitwin 1 ɛn 3. Ivin na kɔntri lɛk Amɛrika, dis sik kin apin to wan ɔ tu pikin dɛn pan wan milyɔn. Dat min se i nɔ kin apin so ɔltɛm. Bɔt if dɛn no dis sik kwik kwik wan ɛn dɛn kin yuz ɔpreshɔn fɔ pul di kansa ɔ lump, di pikin kin wɛl kpatakpata . Sɔntɛnde, fɔ transplant liva na ɔda tritmɛnt opshɔn.

Yu smɔl pikin gɛt ɛni wan pan dɛn sayn ya? Tek tɛm!

Bɔrku kɔmɔn sayn dɛm de wae yu kin si pan di kes wae gɛt ɛpatoblastoma. Bɔt mɛmba se, nɔr frayd fɔ tink se na dis sik jɔs bikɔs yu gɛt dɛn sik ya. Dɛn tin ya kin apin bak bikɔs ɔf ɔda simpul rizin dɛn. Bɔt if dɛn tin ya kɔntinyu, i go fayn fɔ mek yu go to dɔktɔ.

• Bɛlɛ pen (espɛshali na di midul ɔ ɔp rayt say na di bɛlɛ).
• Wan lump we nɔ kɔmɔn na di bɛlɛ. Imajin, we yu de was yu pikin ɔ chenj in klos, yu de fil sɔntin we strenj, lɛk wan swɛlin, na in bɛlɛ.
• Yu nɔ go want fɔ it ɛn yu nɔ go gɛt bɔku bɔku bɔdi (fɔ no rizin). Di pikin nɔ de it bɔku lɛk aw i bin de it bifo ɛn i tan lɛk se i de lɔs in wet.
• Nɔs ɛn vɔmit we de kɔntinyu fɔ de.
• Di skin ɔ di yay we de yɔlɔ (jaundice).

Bɔku tɛm, ɛpatoblastoma na kansa we de gro sloslo . So, yu pikin nɔ go sho ɛni sayn te di kansa tumbu big fɔ afɛkt di bɔdi. Fɔ ɛgzampul, yu pikin kin gɛt bɛlɛ we de at fɔ sɔm dez, ɔ i kin tan lɛk se i de lɔs in wet. Nɔto ɔl di bɛlɛ at na di ɛpatoblastoma. Bɔt if yu gɛt ɛnitin we de mɔna yu, lɛk "dis nɔto jɔs bɛlɛ we de at," nɔ shek fɔ go to yu pikin in dɔktɔ we de mɛn pikin dɛn wantɛm wantɛm.

Wetin mek dis de apin? Wetin na di rizin dɛn?

Infakt, masta sabi bukman dɛn stil nɔ no di rayt we aw di liva sɛl dɛn we gɛt wɛlbɔdi kin tɔn to kansa sɛl dɛn. Bɔt sɔm tin dɛn de we kin mek pɔsin gɛt ɛpatoblastoma:

• fכ bכn wit vεri lכw wet we dεn bכn (we dεn bכn wet sכmtεm sכmtεm 2.4 kilogram).
• di pikin we dεn bכn bifo tεm (dεn bכn am bifo 37 wik).
• Aicardi syndrome: Dis kin mek di pikin in bren ɛn ɔda pat dɛn na di bɔdi nɔ fayn.
• Beckwith-Wiedemann syndrome: Dis kin afɛkt di pikin in divɛlɔpmɛnt ɛn i kin mek i gɛt kansa.
• biliary atresia: Dis kin blok di bayl dakt dεm na yכŋ pikin dεm εn mek di liva pwεl.
• Edwards syndrome (trisomy 18): Dis kin afɛkt di we aw pikin in bɔdi de divɛlɔp.
• famili adenomatous polyposis (FAP): dis kin mek big nכmba fכ sכm sכm sכm sכm sכm sכm dεm (polyps) na di kכlon we kin bi kεnsar.
• Hemihyperplasia: Insay dis, wan say na di pikin in bɔdi kin gro fast pas di ɔda wan.
• Simpson-Golabi-Behmel syndrome (SGB): Dis kin mek pikin dεm na di liva εn כda כgan dεm we nכ de nכmal.

Nɔto ɔl pikin dɛn we gɛt dɛn kayn sik ya go gɛt ɛpatoblastoma. Dɔn bak, pikin we nɔ gɛt ɛni wan pan dɛn tin ya we kin mek i gɛt dis sik. Na dat mek dɛn se dɛn nɔ no di rayt tin we mek i apin.

Lɛ wi lan bak bɔt de kɔmplikɛshɔn (let ifekt) wae kin apun afta tritmɛnt.

Sɔntɛnde di tritmɛnt fɔ kansa fɔ ɛpatoblastoma kin mek i gɛt let ɛfɛkt . Dis na wɛl bɔdi prɔblɛm wae kin apun sɔm mɔnt ɔr ivin sɔm ia afta dɛn dɔn no bɔt ɔr tritmɛnt. Yu pikin kin nid fɔ gɛt lɔng tɛm fɔ fala am ɛn fɔ gɛt mɛrɛsin fɔ mek i ebul fɔ kɔntrol dɛn tin ya.

Sɛkɔn kansa na ɔda ɛgzampul fɔ dis kayn let ɛfɛkt. Dat min se, di divɛlɔpmɛnt fɔ wan nyu kayn kansa mɔnt ɔ ia afta dɛn dɔn dɔn di tritmɛnt fɔ ɛpatoblastoma.

Dɛn tin ya we kin apin let kin afɛkt yu pikin in:

• Di ebul fɔ tink, lan, ɛn mɛmba.
• Grɔw ɛn divɛlɔpmɛnt.
• Di mud, imɔshɔn ɛn mental wɛlbɔdi.
• di כgan dεm we de insay di bכdi εn di tisu dεm.

Nɔ fred dis. Dɔktɔ dɛnsɛf no bɔt dis, so dɛn kin pe atɛnshɔn to tin dɛn lɛk dis.

Aw dɔktɔ dɛn kin no dis sik kɔrɛkt wan?

We yu kɛr yu pikin go to dɔktɔ we de mɛn pikin dɛn, dɛn go du am fɔs fɔ chɛk in bɔdi . Dɛn go aks yu bɔt yu pikin in sik ɛn aw lɔng dɛn dɔn de de. Dɔn, dɛn kin du sɔm tɛst dɛn, lɛk:

• alfa-fetoprotein (AFP) tεst dεm: AFP na tin we di pikin in liva de mek. Dɛn kin chɛk di lɛvul dɛn we i gɛt.
• Kɔmplit blɔd kɔnt (CBC): Dis de sho di kayn blɔd sɛl dɛn we de na di pikin in blɔd ɛn di bɔku bɔku blɔd sɛl dɛn.
• kכmprεhεnsiv mεtabolik panεl (CMP): dis de tεst 14 difrεn tin dεm na di pikin in bכdi εn in liva fכ wok.
• Liva ɛn Dɔpl ɔltrasɔund: Dɛn tin ya kin mek dɔktɔ dɛn tek pikchɔ fɔ di insay pat pan yu pikin in liva.
• Magnetic resonance imaging (MRI): Dis tɛst kin mek yu si rili klia pikchɔ dɛn bɔt di ɔgan dɛn ɛn di blɔd vesel dɛn.
• Vascular ultrasound: dεn kin du dis tεst fכ luk di nεtwכk fכ di bכdi vεsul dεm we de go insay εn kכmכt na di pikin in liva.

Yu dɔktɔ we de mɛn pikin dɛn, if nid de, kin sɛn yu to dɔktɔ we de mɛn pikin dɛn we gɛt kansa, we na dɔktɔ we spɛshal fɔ mɛn kansa pan yɔŋ pikin dɛn.

Aw dɛn kin no di stej dɛm we pɔsin kin gɛt kansa?

Fɔ no di stej we di kansa gɛt rili impɔtant fɔ mek di wan dɛn we de mɛn kansa plan fɔ trit am. Pikin ɔnkɔlɔjis dɛn kin yuz tu klasifikeshɔn sistɛm instead fɔ stej kansa. Dɛn na:

• PRETEXT: Dis tinap fɔ "pri-tritment extent of disease." Bifo di dɔktɔ tek kimotɛrapi, we dɛn kin gi bifo dɛn du di ɔpreshɔn, i kin luk aw fa di kansa dɔn go na di pikin in liva. Dɛn kin chɛk di nɔmba fɔ di kansa nodul dɛn, dɛn saiz, ɛn di kayn we aw dɛn tan.
• POSTTEXT: Dis tinap fɔ "post-treatment extent of disease." I de luk pan di kɔndishɔn afta dɛn dɔn trit am bifo dɛn du di ɔpreshɔn.

Wi liva gɛt tu men pat dɛn (lobes). Di wan dɛn we sabi bɔt kansa kin sheb dɛn tu pat ya to 4 ɔda grup dɛn. Dɛn kin sheb ɛni kategori akɔdin to di nɔmba fɔ di lob dɛn na di liva we gɛt kansa tɔŋ dɛn. as di nכmba fכ di lכb dεm we gεt kεnsar tכmכro de inkrεs, di nכmba fכ di kεtכgrεf dεm de inkrεs bak.

Fɔ ɛgzampul, tink bɔt dis: We dɛn de tɛst am, dɛn kin si tu say dɛn we gɛt kansa na tu difrɛn pat dɛn na di pikin in liva. Dɔn dɛn kin klas di kansa as PRETEXT stej II. If di kemotɛrapi pul wan lump bifo dɛn du di ɔpreshɔn, dɛn kin put di kansa as POSTTEXT stej I. Dɔn di dɔktɔ kin se naw di pikin gɛt stej I ɛpatoblastoma.

Ɔda kayn ɛpatoblastoma na:

• Katej I: Di kansa de na wan pat nɔmɔ na di pikin in liva. Di ɔda tri pat dɛn nɔ kin afɛkt.
• Katej II: Tu kes de fɔ dis. Wan pan dɛn na dat, kansa de na tu pat dɛn we de nia di liva, bɔt i nɔ de na di ɔda tu pat dɛn. Di ɔda wan na dat, kansa de na wan pat, bɔt nɔto tu pat dɛn we nɔ de nia dɛnsɛf.
• Stej III: Kansa de na wan ɔ mɔ pat na di liva, bɔt nɔ kansa de na di pat dɛn we de nia di pat dɛn we gɛt kansa.
• Kategori IV: .Di kansa dɔn skata to ɔl di 4 pat dɛn na di pikin in liva.

Pan ɔl we i kin tan lɛk se dɛn klas ya kɔmplikt smɔl, di dɔktɔ dɛn go ɛksplen dɛn to yu gud gud wan.

Wetin na di tritmɛnt dɛn we dɛn kin gɛt?

Di tritmɛnt we dɛn kin yuz mɔ na fɔ ɔpreshɔn fɔ pul di pat pan di liva we di kansa dɔn afɛkt . Di liva na wan pan di ɔgan dɛn we rili wɔndaful na wi bɔdi. Bikɔs na di wangren ɔgan we kin gro bak afta dɛn dɔn ɔpreshɔn wan pat. Dis min se yu pikin in liva go gro bak lɛk aw i bin de fɔs.

Yu pikin in pikin dɛn we de mɛn kansa kin disayd fɔ gi yu mɔ kemotɛrapi bifo ɛn afta dɛn du di ɔpreshɔn. Dɛn kin yuz dis tritmɛnt fɔ mek di tumbu we gɛt kansa smɔl.

Di pikin kin gɛt kemotɛrapi fɔ lɛk 4 to siks wiks afta dɛn dɔn du di ɔpreshɔn. Dis kemotɛrapi, we dɛn kin gi afta dɛn dɔn ɔpreshɔn, kin mek di chans fɔ mek di kansa kam bak.

Ɔda tritmɛnt dɛn fɔ ɛpatoblastoma na:

• Ablashכn tεrapi: Dis na di minimally invasive prosidכs fכ εpatoblastoma we de kam bak.
• Liva transplant: Dis na opshɔn if di kansa dɔn afɛkt di sɛntral pat na di liva ɔ bɔku pat dɛn na di liva.
• Transarterial chemoemboliization (TACE): Dis prosidur involv fɔ kɔt di blɔd saplai to di kansa tumor ɛn deliv kemotɛrapi drɔgs dairekt to di tumor.

Yu tink se dɛn kin mɛn ɛpatoblastoma?

Yɛs, i kin ebul. Bɔt i dipen pan ustɛm dɛn go no se yu pikin gɛt di sik ɛn aw lɔng dɛn go gɛt tritmɛnt. Epatoblastoma kin wɛl if yu pikin in dɔktɔ ebul fɔ pul ɔl ɔ pat pan di kansa lump .

"Fɔ no bɔt dis sik kwik kwik wan ɛn fɔ trit am kwik kwik wan na tu tin dɛn we rili impɔtant fɔ fɛt dis sik."

Wetin na di rεt dεm wae de liv?

Di rεt wae dεn de liv wit kansa na כnli εstimat bay di εkspiriεns dεm wae pipul dεm wae gεt difrεn kayn kεnsar. Ɔl togɛda, 4 pan 5 pikin dɛn we gɛt ɛpatoblastoma kin liv fayv ia afta dɛn dɔn no se dɛn gɛt di sik .

We yu de tink bɔt aw pɔsin kin wɛl, i impɔtant fɔ mɛmba se di tin we yu pikin kin gɛt kin difrɛn frɔm ɔda pikin dɛn .

Bɔku tin dɛn de we kin afɛkt di prɔgnosis fɔ di ɛpatoblastoma. If yu gɛt kwɛstyɔn bɔt aw pɔsin kin liv, yu pikin in dɔktɔ we de mɛn pipul dɛn we gɛt kansa na in na di bɛst tin fɔ no bɔt. I kin ɛksplen wetin dɛn nɔmba ya min pan yu pikin in kes.

Ustɛm mi pikin fɔ go to dɔktɔ?

Yu pikin fɔ gɛt apɔntinmɛnt fɔ fala am ɔltɛm wit di tim we de kia fɔ di kansa. Di tim go de chɛk yu pikin in wɛlbɔdi ɔltɛm, ivin ɛnitin we go apin let. Dɛn go chɛk bak fɔ sayn dɛm fɔ hepatoblastoma we de kam bak ɔ nyu kansa.

Ustɛm a fɔ kɛr mi pikin go na di Imejɛnsi Rum?

Bɔku tɛm, dɛn kin du ɔpreshɔn pan di tritmɛnt fɔ di ɛpatoblastoma. Ɔpreshɔn kin mek prɔblɛm dɛn lɛk fɔ gɛt infɛkshɔn. Tek yu pikin go na di imejensi rum wantɛm wantɛm if ɛni wan pan dɛn tin ya apin:

• If di fiva pas 100.4 digri F (38.3 digri sɛlshiɔs).
• If di say we dɛn du di ɔpreshɔn na dak rɛd, ɔ if i tan lɛk se di pikin de fil pen we yu tɔch am.
• If grɛn ɔ yɔlɔ wata kɔmɔt na di say we dɛn du di ɔpreshɔn.

Aw yu go ɛp yu pikin wit dɛn tɛst ɛn tritmɛnt ya?

I impɔtant fɔ du tɛst fɔ no wetin mek yu pikin sik. Bɔt nidul fɔ pul blɔd kin at. Pikin dɛn kin fred bikɔs ɔf di nɔys we di MRI mashin dɛn kin mek. Pikin dɛn kin fil wɔri ɛn fred fɔ kemotɛrapi ɔ ɔpreshɔn. I rili kɔmɔn fɔ mek pikin du dis kayn we we dɛn gɛt kansa. Fɔ wok wit pikin layf spɛshal pɔsin dis tɛm kin bi big ɛp fɔ yu pikin (ɛn yu) as dɛn de go tru dɛn tɛst ɛn tritmɛnt ya.

We yu kam fɔ no se yu pikin gɛt ɛpatoblastoma, yu kin fil bɔku bɔku tin dɛn. Pan ɔl we yu kin tray fɔ mek yu nɔ gɛt wanwɔd na do, yu kin fil lɛk se yu de fɔdɔm na do. Dis na tɛm we rili at fɔ du. Pan ɔl we dɛn kin mɛn ɛpatoblastoma wit tritmɛnt, fɔ dil wit di tritmɛnt kin bi prɔblɛm fɔ di pikin ɛn di wan dɛn we dɛn lɛk.

Di dɔktɔ we de mɛn yu pikin ɛn di ɔda wan dɛn we de kia fɔ am ɔndastand dɛn prɔblɛm dɛn ya. Dɛn go du ɔl wetin dɛn ebul fɔ mek di tritmɛnt izi as dɛn ebul. Dɛn go gladi bak fɔ ɛksplen wetin yu go ɛkspɛkt ɛn aw yu go ɛp yu pikin. Mɛmba se nɔto yu wangren de.

Fɔ dɔn, di tin dɛn we impɔtant pas ɔl fɔ mɛmba (Take-Home Message) .

• Epatoblastoma na wan kansa we nɔ kin bɔku na di liva we kin mɔs afɛkt yɔŋ pikin dɛn we ol bitwin 1-3 ia.
• Yu fɔ no bɔt di sayn dɛm lɛk bɛlɛ pen, blo, nɔr kin want fɔ it, yu nɔr kin gɛt bɔku bɔku bɔdi, yu kin vɔmit ɔltɛm, ɛn yu kin gɛt janda. Nɔ panik jɔs bikɔs yu gɛt dɛn tin ya, bɔt go to dɔktɔ.
• Dis sik kin mɛn mɔ if dɛn no am kwik ɛn trit am kwik kwik wan .
• Di tritmɛnt dɛn we dɛn kin gɛt na ɔpreshɔn, kemotɛrapi, ɛn transplant liva.
• Let ifekt kin apin afta tritmɛnt, so fɔ fala fɔ lɔng tɛm impɔtant.
• Kɔntinyu fɔ tɔk fayn to yu pikin in dɔktɔ. Aks ɔl yu kwɛstyɔn dɛn ɛn tin dɛn we de mɔna yu.
• Gɛt sɔpɔt pan yu maynd ɛn filin fɔ yusɛf ɛn yu pikin we yu de travul.

A op se dis infɔmeshɔn go ɛp yu fɔ gɛt sɔm ɔndastandin bɔt dis rare kɔndishɔn. A de wish yu pikin fɔ wɛl kwik kwik wan!

` Epatoblastoma, liva kansa, pikin kansa, bɛlɛ pen, liva, kansa simptom, kansa tritmɛnt