We yu dɔktɔ gi yu wan mɛrɛsin we dɛn kɔl Larotrectinib fɔ yu ɔ pɔsin we yu sabi, i nɔmal fɔ gɛt bɔku kwɛstyɔn bɔt am. Us kayn drɔg dis? Wetin go apin wit am? Ɛni bad bad tin dɛn de we kin apin to am? Sɔntɛm yu go de wɔnda. Nɔ wɔri. Lɛ wi tɔk bɔt dis drɔg simpul wan, insay wan we we yu go ɔndastand.
Wetin na Larotrectinib?
Fɔ tɔk am simpul wan, larotrectinib na spɛshal kayn mɛrɛsin we de stɔp di kansa sɛl dɛn fɔ gro. Dɛn kɔl dis ‘targeted therapy’. Dis min se dis mɛrɛsin de go dairekt to ɛn afɛkt wan patikyula prɔtin nɔmɔ we de na di kansa sɛl dɛn, ɛn dis kin mek dɛn sɛl dɛn de nɔ gro.
Bɔt dis nɔto mɛrɛsin we dɛn kin gi ɔl kayn kansa. dεn de tεst yu kεnsar sεl dεm fכ si if dεn gεt spεshal mכtεshכn insay wan jin we dεn kכl NTRK (neurotrophic receptor tyrosine kinase gene fusion) . Na pipul dɛn nɔmɔ we gɛt da jɛnɛtik muteshɔn de go bɛnifit frɔm dis mɛrɛsin. So if yu dɔktɔ dɔn tɛl yu dis mɛrɛsin, dat min se yu kayn kansa go mɔs du am fayn.
Tin dɛm fɔ tɛl yu dɔktɔ bifo yu bigin fɔ tek mɛrɛsin
Bifo yu bigin dis mɛrɛsin, i rili impɔtant fɔ gi yu dɔktɔ kɔmplit diskripshɔn bɔt yu wɛlbɔdi kɔndishɔn. Mek shɔ se yu tɛl dɛn mɔ bɔt dɛn tin ya:
| Pozishɔn | Wetin yu nid fɔ tɛl |
|---|---|
| Liva sik | If yu gɛt ɛni sik na yu liva. |
| Dizayd na di nerve | If yu an ɛn fut dɛn de tingling ɔ yu gɛt ɔda prɔblɛm dɛn wit yu nerve. |
| Alɛji dɛn we pɔsin kin gɛt | If yu gɛt alɛji fɔ dis mɛrɛsin, ɔda mɛrɛsin, it, ɔ day. |
| We uman gɛt bɛlɛ | If yu gɛt bɛlɛ, yu de tray fɔ gɛt bɛlɛ, ɔ yu gɛt ɛni dawt bɔt am. |
| Fɔ gi pikin in mama in bɛlɛ | If yu de gi yu pikin in bɛlɛ. |
Aw a fɔ yuz dis mɛrɛsin?
Di tin we impɔtant pas ɔl na fɔ tek di mɛrɛsin jɔs lɛk aw di dɔktɔ se.
- Swɛla dis kapsul ɔl wit wan glas wata .
- Nɔ brok, krɔs, ɔ chew di kapsul.
- Yu kin tek dis bifo ɔ afta yu it. Bɔt, tray fɔ tek am di sem tɛm ɛvride .
- I rili impɔtant: Nɔ ɛva tek dis mɛrɛsin wit grep jus.
- Nɔ stɔp fɔ tek yu mɛrɛsin if yu dɔktɔ nɔ advays yu.
If dɛn gi am to pikin dɛn: Sɔntɛnde dɛn kin gi dis mɛrɛsin ivin to yɔŋ pikin dɛn. Bɔt, i nid fɔ tek tɛm wit spɛshal tin dɛn. Tɔk to yu dɔktɔ we de mɛn pikin dɛn bɔt dis.
Wetin fɔ du if di doz go ɔp (ɔvados)?
If yu tink se yu dɔn tek dis mɛrɛsin tumɔs, nɔ panik. Wantɛm wantɛm kɔl di Nashɔnal Pɔyzin Infɔmeshɔn Sɛnta na di Kɔlɔmbɔ Nashɔnal Ospital . Ɔ go na di Imejɛnsi Tritmɛnt Yunit (ETU) na di ɔspitul we de nia yu.
Wetin a go du if a fɔgɛt fɔ tek mi mɛrɛsin?
If yu mis wan doz, tek am jɔs afta yu mɛmba. Bɔt if i nɔ rich 6 awa te yu tek yu nɛks doz, skip di doz we yu mis ɛn tek yu nɛks doz di tɛm we yu dɔn sɛtul. Nɔ ɛva tek tu dos wan tɛm.
Ɔda tin dɛm wae kin intarakt wit dis mɛrɛsin (Interactions) .
Dis mɛrɛsin kin miks wit ɔda mɛrɛsin ɛn it dɛn. So, tɛl yu dɔktɔ bɔt ɔltin we yu de tek. Dis inklud mɛrɛsin dɛn we dɛn kin gi pɔsin, mɛrɛsin dɛn we dɛn kin bay we dɛn nɔ kin bay, mɛrɛsin dɛn we dɛn kin yuz fɔ mɛn animal dɛn, vaytamɛn dɛn, ɛn sɔpɔtmɛnt dɛn. Dɔn bak, tɛl yu dɔktɔ if yu de smok ɔ drink rɔm.
Dis dɔŋ ya na sɔm tin dɛm wae kin intarakt wit dis mɛrɛsin.
- Mɛrɛsin fɔ HIV ɔ AIDS
- Sɔm antibayɔtiks (lɛk klarithromycin) .
- Mɛrɛsin fɔ fungal infɛkshɔn (lɛk ketoconazole) .
- Mεdisin dεm fכ εpilepshכn (lεk carbamazepine, phenytoin) .
- Sɔm mɛrɛsin dɛn we de mek pɔsin gɛt at sik
- Di mɛrɛsin dɛn we de mek di bɔdi nɔ gɛt bɛtɛ wɛlbɔdi (lɛk sayklɔspɔrin, takrolimus) .
- Sɔm mɛrɛsin dɛn we de agens kansa (kimotɛrapi) .
- Di herb we dɛn kɔl Sɛnt Jɔn Wɔt
- Grepfruit jus we dɛn kin mek
Dis list nɔ kɔmplit, so i impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di mɛrɛsin dɛn we yu de tek.
Tin dɛn we yu fɔ tink bɔt we yu de tek mɛrɛsin
- Blɔd tɛst: We yu de tek dis mɛrɛsin, yu dɔktɔ go ɔda fɔ du blɔd tɛst wan wan tɛm fɔ chɛk tin dɛn lɛk aw yu liva de wok.
- Di wok dɛn we yu fɔ pe atɛnshɔn to: Dis mɛrɛsin kin mek yu fil lɛk yu ed, yu kin slip, ɔ yu kin kɔnfyus. So, nɔ du tin dɛn we yu nid fɔ pe atɛnshɔn to, lɛk fɔ drayv ɔ fɔ yuz mashin, te yu no gud gud wan aw dis kin afɛkt yu bɔdi.
- Bεlε εn we yu de gi pikin bεlε (i rili impɔtant):
- Uman: Nɔ gɛt bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ at le wan wik afta yu dɔn stɔp di mɛrɛsin. If yu de plan fɔ gɛt bɛlɛ ɔ yu tink se yu gɛt bɛlɛ, tɛl yu dɔktɔ wantɛm wantɛm.
- Man dɛm: Nɔ fɔ bɔn pikin we yu de tek dis mɛrɛsin ɛn fɔ at le wan wik afta yu dɔn stɔp di mɛrɛsin.
- Nɔ gi yu pikin in bɛlɛ we yu de tek dis mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp.
- Fɔ bɔn pikin: Dis mɛrɛsin kin afɛkt di we aw yu ebul fɔ bɔn pikin. If yu gɛt ɛni kwɛstyɔn bɔt dis, tɔk to yu dɔktɔ.
Di sayd ɛfɛkt dɛn we di mɛrɛsin kin gɛt
Lɛk ɛni mɛrɛsin, dis wan kin gɛt sayd ɛfɛkt. Sɔm na smɔl smɔl tin dɛn, ɛn ɔda wan dɛn nid fɔ pe atɛnshɔn to dɛn wantɛm wantɛm.
| Sayd ɛfɛkt dɛn we yu fɔ ripɔt to yu dɔktɔ wantɛm wantɛm | |
|---|---|
| Alɛji we pɔsin kin gɛt | Skin rash, it, swel na di fes, lip ɔ tong. |
| Sayn dɛn we de sho se pɔsin in liva wund | Dak yɔlɔ/brawn urine, yu yay ɔ skin de yɔlɔ, pen na di ɔp rayt pat na di bɛlɛ, nɔs, yu nɔ de want fɔ it, yu stɔl de pale. |
| Prɔblɛm dɛn we de na di nervɔs sistɛm | Diziz, kɔnfyushɔn, lɔs balans, pen ɔ swɛ na yu an ɛn fut, at fɔ tɔk. |
| Kɔmɔn sayd ɛfɛkt dɛm we dɛn fɔ ripɔt to di dɔktɔ if dɛn kɔntinyu fɔ de | |
| Fɔ vɔmit | Rɔnbɛlɛ |
| Banbɛlɛ | Kɔf |
| We pɔsin taya | |
If yu gɛt ɛni ɔda kayn sik we nɔ kɔmɔn we dɛn nɔ tɔk bɔt na dis list, tɔk to yu dɔktɔ bɔt dɛn bak.
Mɛsej we dɛn kin kɛr go na os
- Larotrectinib na wan tεrapi we dεn tכk bכt spεshal fכ kεnsar dεm wit NTRK jin fכs.
- I impɔtant fɔ tɛl yu dɔktɔ bɔt ɔl di ɔda mɛrɛsin dɛn, ɛbul prɔdak dɛn, ɛn sɔpɔtmɛnt dɛn we yu de tek.
- Nɔ drink grep jus ɔltogɛda we yu de tek dis mɛrɛsin.
- Fɔ fala di strikt tin dɛn fɔ tek tɛm wit bɛlɛ, fɔ gi pikin in bɛlɛ, ɛn fɔ bɔn pikin we yu de tek di mɛrɛsin ɛn fɔ wan wik afta yu dɔn stɔp.
- Go to dɔktɔ kwik kwik wan if yu gɛt sɔm sayn dɛn lɛk we yu liva dɔn pwɛl ɔ yu gɛt siriɔs nyurolɔjik prɔblɛm.
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