Sɔntɛnde wi kin aks wisɛf se, "A gɛt famili histri bɔt kansa, so a kin wɔnda if a go mɔs gɛt am bak." Infakt, sɔm kayn kansa kin kɔmɔt frɔm di jɛnɛreshɔn inflɔwɛns we kin pas frɔm wan jɛnɛreshɔn to jɛnɛreshɔn. Fɔ ɛgzampul, Lynch Syndrome na wan sik wae de mek pɔrsin gɛt kansa pasmak, bɔt dɛn nɔr kin tɔk bɔt am bɔrku. I rili impɔtant fɔ no bɔt dis. So lɛ wi tɔk bɔt am jɔs tide.
Fɔ tɔk am simpul wan, wetin na Lynch Syndrome?
Lynch syndrome na wan sik we de kɔmɔt frɔm in mama ɔ papa to pikin, ɔ we pɔsin kin gɛt frɔm in mama ɛn papa . Pɔsin wae gɛt dis sik kin gɛt bɔrku kayn kansa, ɔr kin gɛt sɔm kayn kansa pas ɔda pipul dɛm.
spεshal wan, pכsin we gεt dis kכndyushכn gεt 40% to 80% hכy chans fכ gεt k כlכrektal kεnsar we i ol 70. I de bak fכ gεt kεnsar na di uterus, ovaria, εn bεlε. Wetin spɛshal bɔt dis na dat, kansa kin kam bifo bɔku tɛm pas di nɔmal ej fɔ kansa, sɔntɛm na di 30 ɔ 40 ia.
Trade, dɔktɔ dɛn bin de kɔl am bak HNPCC (Hereditary Non-Polyposis Colorectal Cancer), bɔt naw dɛn de yuz di nem Lynch syndrome mɔ.
Wetin na di rizin we mek dis kayn tin de apin?
Fɔ ɔndastand dis, lɛ wi tink bɔt wi bɔdi fɔ smɔl tɛm. Wi bɔdi gɛt bɔku bɔku sɛl dɛn. Dɛn sɛl dɛn ya de sheb ɔltɛm ɛn mek nyu sɛl dɛn. Tink bɔt am lɛk we yu de mek kɔpi wit fotokɔpi mashin. We di sɛl dɛn sheb dis we, sɔntɛnde smɔl mistek dɛn kin apin. bכt bכt bכt bכt wi bכdi in DNA gεt spεshal ‘mismatch repair genes’ we de no dεn mistek dεm ya εn kכrekt dεm.
Pɔsin we gɛt Lynch syndrome gɛt difrɛns ɔ mistek pan wan pan dɛn ‘chɛk jin’ ya . Dɔn we dɛn sɛl dɛn de sheb, dɛn nɔ kin kɔrɛkt di ɔda mistek dɛn, ɛn di sɛl dɛn we nɔ fayn kin kɔntinyu fɔ sheb, ɛn bɔku ɔda sɛl dɛn we nɔ fayn kin bigin fɔ mek na di bɔdi. As tɛm de go, dɛn sɛl dɛn ya we nɔ fayn kin bi kansa.
If yu mama ɔ papa gɛt dis sik, yu gɛt 50% chans fɔ gɛt am bak.
Wetin na di sayn dɛm wae kin sho se yu gɛt Lynch syndrome?
Bɔku impɔtant tin dɛn de we kin mek pipul dɛn wɔri bɔt dis sik. If wan ɔ mɔ pan dɛn tin ya apin to yu ɔ yu famili, i rili impɔtant fɔ tɔk to dɔktɔ.
| Ustɛm fɔ sɔprayz se yu gɛt Lynch Syndrome | |
|---|---|
| Pɔsin in yon kansa istri | Yu gɛt kɔlorektal kansa bifo yu ol 50 ia. |
| Famili kansa istri |
|
| Tumɔs dɛn we nɔ gɛt kansa | Polips, na wan kayn we we nɔ gɛt kansa we de gro na di kɔlon, kin apin we dɛn yɔŋ. |
Aw fɔ no dis sik?
If yu ɔ sɔmbɔdi na yu famili dɔn gɛt kansa ɛn yu dɔktɔ tink se i kin bi bikɔs ɔf Lynch syndrome, dɛn kin tɛst smɔl pan di kansa. Tu men we dɛn de fɔ du dis:
- Immunohistochemistry (IHC) test: Dis de tεst fכ di kayn protin dεm we de insay di kεnsar sεl dεm. if di protin dεm we di ‘chεka jin dεm’ we wi bin tכk bכt de mek nכ de insay dεn sεl dεm, i kin bi sayn fכ Lynch sεndrכm.
- Maykrosataylayt instεbiliti (MSI) tεst: Dis de chεk dεn wan dεm fכ mistek dεm na di DNA fכ di kεnsar sεl dεm.
If dɛn tɛst ya kɔnfirm se yu gɛt Lynch syndrome, ɔ if yu tink se yu de pan denja bikɔs sɔmbɔdi na yu famili gɛt dis sik, yu kin mek dɛn du wan jenɛtik tɛst pan blɔd sɛmpul fɔ no fɔ tru if yusɛf gɛt dis jenɛtik dɛfɛkt.
Sɔpɔt frɔm wan Jɛnɛtik Kɔnsul
Dis tɛm ya, yu dɔktɔ kin sɛn yu to pɔsin we de advays yu bɔt yu jɛnɛtiks. Dɛn go ɛksplen bɔku tin to yu bɔt dis.
- Aw dɛn kin gɛt Lynch syndrome na famili.
- Wetin di rizɔlt fɔ yu jenɛtik tɛst ripɔt min.
- Aw dɛn rizɔlt ya kin afɛkt yu kansa risk.
- Di prɔbabiliti se yu pikin dɛn go gɛt dis jin frɔm yu.
- Yu opshɔn dɛm fɔ mek yu nɔ gɛt kansa.
Mɛmba se, if yu no se yu gɛt Lynch syndrome , dat nɔ min se yu go mɔs gɛt kansa . I jɔs min se yu risk bɔku pas ɔda pipul dɛn.
If yu gɛt Lynch syndrome, aw dɛn kin mɛn am?
Di bɛst tin fɔ du we yu no se yu gɛt dis sik na fɔ go fɔ chɛk ɔltɛm fɔ chɛk if yu gɛt kansa. Dɔn, ilɛksɛf kansa gɛt kansa, i go mɔs bi se dɛn go no am kwik kwik wan ɛn i go wɛl kpatakpata . fכ egzampl, kכlon kεnsar kin kכl insay 90% pan di kes dεm if dεn no am kwik.
Yu dɔktɔ go disayd us tɛst yu nid fɔ du ɛn aw ɔltɛm yu nid fɔ du am. Di tɛst dɛm we dɛn kin rɛkɔmɛnd na:
- Kolonoskopi: Frɔm we yu ol 20-25 ia, dɛn kin aks yu fɔ du dis tɛst ɛvri ia ɔ tu ia. Dis de chɛk fɔ polip ɔ sayn dɛm fɔ kansa na di big intestinal.
- εndoskopi: Frɔm we yu ol 30 ia, yu kin du dis ɛvri 3-5 ia fɔ chɛk di bɛlɛ ɛn di intestinal.
- tεst fכ uman dεm: afta dεn ol 30 ia, dεn kin rεkomεnd fכ tεst lεk fכ du di bכdi εgzam, transvaginal ultrasound, כ uterin biopsy εvri ia fכ chεk di uterus εn ovaries.
Sɔm pipul dɛn, mɔ di uman dɛn we dɔn bɔn pikin, kin tɔk to dɛn dɔktɔ bɔt aw fɔ du ɔpreshɔn fɔ mek dɛn nɔ gɛt kansa. Dis min se dɛn fɔ ɔpreshɔn di kɔlon, di uterus, ɔ di ovaria bifo kansa bigin. Dis na sɔntin we pɔsin kin disayd fɔ du.
Di impɔtant tin fɔ liv fayn layf
Pan ɔl we yu kin gɛt chɛk-ap ɔltɛm, fɔ liv fayn layf kin ɛp bak fɔ ridyus dis prɔblɛm.
- It it we gɛt bɔku vɛjitebul, frut, ligɛm, ɛn ɔl gren.
- Du ɛksɛsayz ɔltɛm .
- Kɔntrol yu wet.
- Limit fɔ drink rɔm.
Sɔm stɔdi dɔn sho se fɔ tek wan smɔl smɔl aspirin ɛvride kin ridyus dis risk, bɔt dɛn nid fɔ du mɔ risach bɔt dis. So , nɔ ɛva bigin fɔ tek mɛrɛsin fɔ yusɛf we yu nɔ go to yu dɔktɔ.
Mɛsej we dɛn kin kɛr go na os
- Lynch syndrome na wan jεnεtik kכndyushכn wae de pas dכn tru jεnereshכn. I de mek di risk fɔ gɛt bɔku kansa dɛn, lɛk kansa na di kɔlon ɛn di uterin.
- If pɔsin na yu famili dɔn gɛt kansa we i yɔŋ (espɛshali na di kɔlon ɔ di uterus), dat kin mek i gɛt kansa.
- If yu gɛt ɛni dawt ɔ wɔri bɔt dis, mek shɔ se yu tɔk to yu dɔktɔ. I go gi yu di advays we yu nid.
- We dɛn no se yu gɛt dis sik, dat nɔ min se kansa go gɛt. Na chans fɔ tek step fɔ protɛkt yusɛf frɔm kansa kwik kwik wan.
- Fɔ de skrin ɔltɛm na yu wɛpɔn we gɛt pawa pas ɔl. Ivin if kansa kin apin, dɛn kin kech am kwik ɛn dɛn kin trit am fayn.
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