Wetin na Mantle Cell Lymphoma? Lɛ wi tɔk bɔt am!

Yu nɔ go ivin no se sɔntɛnde, fɛt-fɛt dɛn kin de we wi nɔ de tɔk natin insay wi bɔdi. Fɔ ɛgzampul, Mantle Cell Lymphoma (MCL) na wan kansa we nɔ kin apin so ɔltɛm we kin bigin na wi wayt blɔd sɛl dɛn we dɛn kɔl limfosayt. Na tru tru wan kayn limfoma we dɛn kɔl nɔ-Hɔdgkin limfoma. Lɛ wi tɔk bɔt dis simpul wan, di we we yu go ɔndastand.

Aw di mantle cell lymphoma (MCL) de divεlכp? Wetin kin apin to di bɔdi?

Imajin, dis kansa we dεn kכl MCL de stat fכ spre rili slo εn tif na di bכdi fכs. Bɔt afta sɔm tɛm, i kin gro kwik kwik wan wantɛm wantɛm. dis kin mεntal sכprεd כlsay na wi limfatik sistεm. di limfatik sistεm na wan kayn wata we de insay wi bכdi εn na nεtwכk fכ di vεsεl dεm we de kכri da wata de. I tan lɛk wan sistɛm we de pul dɔti na wi bɔdi. We di sik wɔs smɔl , dɛn kansa sɛl ya kin kɔmɔt na di limf no dɛm ɛn go na wi blɔd, bon mɛro, ɛn sɔntɛnde ivin go na say dɛm lɛk di dijestiv sistɛm.

Impɔtant tin na dat, pɔrsin wae gɛt MCL kin gɛt sɔm tɛm wae i kin gɛt di sik, ɛn dɛn kin gɛt bak di sik bak. Dis kin apin bɔku tɛm. Pan ɔl we tritmɛnt nɔ kin ebul fɔ mɛn MCL ɔltogɛda, i kin ɛp fɔ mek di tɛm we di sik nɔ de igen fɔ lɔng tɛm.

Mantle cell lymphoma na kansa we nɔ kin bɔku . I kin afɛkt lɛk wan pan ɛvri 200,000 pipul dɛn. Pan ɔl we ɛnibɔdi kin gɛt dis kansa, pipul dɛn we ol bitwin 60 ɛn 70 ia kin gɛt dis kansa smɔl.

Wetin na di kayn mantle cell lymphoma (MCL)?

Tu men kayn MCL de: 1. Klasik MCL: Dis na di kayn we we kɔmɔn pas ɔl. i de stat na di limf no dεm εn i de spre to כda pat dεm na di bכdi. Bɔku tɛm, na wan kayn we we kin agresiv mɔ. 2. lukemik nכn-nodal MCL: dis kayn kin involv wan big splin εn limfoma sεl dεm na di bכdi εn bon mכro. I de gro sloslo pas di klasical tayp.

Wetin na di sayn dɛm fɔ dis sik? Aw yu no am?

MCL simptom kin difrɛn frɔm wan pɔrsin to ɔda pɔrsin. Sɔmtɛm dɛn kin tan lɛk sayn dɛm fɔ wan kɔmɔn sik, so yu nɔr kin ivin tink se na kansa. Na dat mek dɛn kin no MCL let, we di sik dɔn ɔlrɛdi skata. Sɔntɛm yu nɔ go gɛt ɛni sayn atɔl. Bɔt if yu gɛt sɔm sayn dɛn, dɛn kin inklud:

• Brus we de mek pɔsin brus
• Ed de at
• Fɔ fil taya ɔltɛm ( Fatigue ) .
• Fiva
• Bɛlɛ we de mek yu at pwɛl
• Fil fɔ it
• Fɔ di nɛtWe pɔsin de swet
• di limf no dεm we swεla (lεk na di nεk, di armpit, di groin) .
• Fɔ fil se yu wik
• We yu de lɔs yu wet fɔ natin

Nɔr frayd MCL jɔs bikɔs yu gɛt dɛn sik ya. Bɔt if dɛn sik ya kɔntinyu, i go fayn fɔ mek yu go to dɔktɔ .

Wetin kin mek pɔsin gɛt mantle cell lymphoma (MCL)?

כl di tεm dεm, MCL de kכz fכ wan mכtεshכn na sכm pan wi jin dεm. dis mכtεshכn de chenj di we aw wi B sεl dεm, we na wan kayn limfosayt, de wok. Risach pipul dεm nכ no εksεkshכn wetin mek dis mכtεshכn de apin. bכt na wetin de apin: 1. di B sεl dεm we nכmכl mכt de prodyuz tu mכch wan protin we dεn kכl sayklin D1. dis protin de εp di B sεl dεm fכ gro. 2. di εksyכs prodakshכn fכ dis sayklin D1 protin de mek di B sεl dεm de divayd εn mכltiply we dεn nכ de kכntro. 3. di sεl dεm we de divayd we dεn nכ de kכntro de kכlכp tכgeda fכ mek tכmכro.

Wetin na de prɔblɛm wae kin kam wit dis sik?

as di mantle sel limfoma de go bifo, di komplikashכn dεm lεk:

• Blɔd we de kɔmɔt na di bɛlɛ
• Spleen we dɔn brok
• Tumor lysis syndrome (na wan kɔmplikeshɔn we kin kam bikɔs di kansa sɛl dɛn kin brok kwik kwik wan) .

Aw dɛn kin no se pɔsin gɛt mantle cell lymphoma (MCL)?

If yu dɔktɔ sɔprayz se yu gɛt MCL, i go mɔs bi se dɛn go du bɔku tɛst dɛn.

• Lab test: Dɛn tin ya kin inklud fɔ kɔmplit blɔd kɔnt (CBC), kɔmprɛhɛnsif mɛtabolik panɛl (CMP), LDH tɛst, ɔ yurik asid lɛvɛl tɛst. Bɔku tɛm, dɔktɔ dɛn kin dawt if dɛn si se di nɔmba fɔ di limfosayt dɛn de bɔku we dɛn de du blɔd tɛst.
• Bayopsi: Yu dɔktɔ kin se yu fɔ tek limf node bayɔpsi ɔ bon mɛro bayɔpsi fɔ no if kansa sɛl dɛn de. di tisu sεmpl na wan patכlכjist de egzamin am.
• Imej tɛst: Dɛn tɛst ya kin ɛp fɔ si aw fa di kansa dɔn skata. Dipen pan usay di kansa de, yu kin nid fɔ gɛt kɔlon skan, CT skan, EGD (ɛsophagogastroduodenoscopy), ɔ PET skan.

If di blɔd tɛst rizɔlt nɔr fayn, yu dɔktɔ go chɛk yu ɛn aks yu bɔt yu sik. Dɛn kin fil bak say dɛm lɛk yu nɛk ɛn yu armpit fɔ si if yu limf no dɛm dɔn swel.

Wetin na di stej dɛm fɔ mantle cell lymphoma (MCL)?

Dɔktɔ dɛn kin sheb di sik to difrɛn stej dɛn bay aw i dɔn skata fa fawe. Dɛn kin yuz wan spɛshal sistɛm we dɛn kɔl di Mantle Cell Lymphoma International Prognostic Index (MIPI). Dis kin gi rough idea of ​​aw lɔng pɔrsin kin ɛkspɛkt fɔ liv. In jɛnɛral, di sik kin kam bak leta pas di fɔs stej. Di stej na aw fa di kansa dɔn skata:

• Stej I: I de limited to wan ɔ sɔm limf no dɛm na di sem eria.
• Stej II: I dɔn spre to tu ɔ mɔ limf no dɛm na di sem say na yu dayafragm.
• Stej III: I dɔn spre to ɔl tu di say dɛm na di dayafragm, ɔ to di splin ɛn limf no dɛm we de ɔp di dayafragm.
• Stej IV: di mantle sεl limfoma dεn dכn spre to fa fa say dεm na di bכdi, כ to כda say dεm we nכ de na di limf no dεm.

Aw dɛn kin trit mantle cell lymphoma (MCL)?

Di tritmɛnt fɔ MCL nɔto di sem fɔ ɔlman. De tritmɛnt wae fayn fɔ yu kin dipen pan tin dɛm lɛk usai de kansa de ɛn aw i de gro fast. Na sɔm pan di tritmɛnt dɛm wae de fɔ MCL:

• Kimotɛrapi: Na drɔgs we dɛn kin gi fɔ pwɛl di kansa sɛl dɛn.
• Immunotherapy: Na tritmɛnt we de mek yu bɔdi in yon imyun sistɛm fɔ fɛt kansa.
• Radieshɔn tɛrapi: Fɔ pwɛl di kansa sɛl dɛn we yu de yuz ay ɛnaji rayt.
• Targeted therapy: Na Drug wae de target spεshal mכlikul dεm wae de εp di kεnsar sεl dεm fכ gro εn spre.
• stεm sεl transplant: Transplant fכ hεlty stεm sεl dεm fכ riples di bon mכro we sik.

Yu kin kwalifay fɔ sɔm pan dɛn tritmɛnt ya, ɛn yu nɔ kin kwalifay fɔ sɔm.

If yu gɛt MCL, i fayn bak fɔ tink bɔt klinik trial dɛm we de tɛst nyu tritmɛnt dɛm. Dɛn nyu tritmɛnt ya nɔ go ebul fɔ mɛn MCL ɔltogɛda, bɔt dɛn kin gi yu mɔ tɛm fɔ liv gladi layf, we nɔ gɛt ɛni sik. Aks yu dɔktɔ bɔt dis.

Yu tink se dɛn kin ebul fɔ mek dɛn nɔ gɛt mantle cell lymphoma (MCL)?

I sɔri fɔ no se dɛn nɔ go ebul fɔ stɔp MCL. Jɔs bikɔs yu gɛt dis sik nɔ min se yu du ɛnitin we nɔ rayt. Risach pipul dεm stil de tray fכ no wetin mek di jin dεm na wi bכdi de chenj (mutate) insay we dεm we de mek kansa lεk MCL.

Aw layf tan lɛk wit mantle cell lymphoma (MCL)?

Mantle cell lymphoma nɔto wan kayn limfoma we pɔsin kin mɛn ɔltogɛda. Bɔt, tritmɛnt dɛn de wae kin ɛp yu fɔ go na remission. Fɔ de na rɛmishɔn nɔ min se di kansa dɔn wɛl ɔltogɛda. MCL kin kam bak afta sɔm mɔnt ɔ ia. Di tɛm we yu de na rɛmishɔn wit MCL kin shɔt. Bɔt dɛn dɔn sho se nyu tritmɛnt dɛn we dɛn dɔn tɔk bɔt kin bɔku dis tɛm. Tɔk to yu dɔktɔ fɔ no mɔ bɔt yu prɔgnosis.

Di rit we pipul dɛn kin liv

di fayv ia sכvayv rεt fכ mantle sεl limfoma na bכt 50%. Dis min se lɛk af pan di pipul dɛm we dɛn no se gɛt dis sik stil de alayv fayv ia afta dɛn dɔn no se dɛn gɛt dis sik.

Bɔt mɛmba se dɛn kayn we ya we pipul dɛn kin liv na jɔs sɔm tin dɛn we dɛn kin tɔk bɔt. Dɛn nɔr kin tɛl yu ustɛm aw lɔng yu go liv ɔr aw yu go ansa ɛni tritmɛnt. I bɛtɛ fɔ tɔk to yu dɔktɔ fɔ no aw dɛn ret ya de apin to yu.

Aw yu de kia fɔ yusɛf?

I rili impɔtant fɔ tek kia ɔf yusɛf pan bɔdi, maynd, ɛn filin we yu de liv wit mantle cell lymphoma. Na sɔm advays dɛn we go ɛp yu:

• Aksept aw yu de fil: Fɔ stɔp filin lɛk pwɛl hat ɛn frayd nɔr go mek dɛn nɔr de igen. Fɔ ɔndastand ɛn alaw aw yu de fil fɔ sho tru na di fɔs tin we yu fɔ du fɔ fɛn di sɔpɔt we yu nid.
• Gɛt sɔpɔt: I fayn fɔ jɔyn sɔpɔt grup wit pipul dɛn we de go tru di sem kayn ɛkspiriɛns. Aks yu dɔktɔ bɔt grup dɛn na yu eria ɔ na di Intanɛt.
• Manej di strɛs: Fɛn we fɔ rilaks. Tray fɔ du ɛksesaiz fɔ tink gud wan, lɛk fɔ tink gud wan.
• Gɛt insay wan rutin: Di saykl fɔ rεmishɔn ɛn rilaps fɔ di sik kin mek ɔltin fil chaotic. If yu mek wan rutin fɔ di tin dɛn we yu de du ɛvride ɛn fɔ fala am, dat go ɛp yu fɔ gɛt sɔm kɔntrol.
• Tɔk to pɔsin we de advays yu: I impɔtant fɔ tek kia ɔf yu maynd wɛlbɔdi. Wan pɔsin we de gi advays ɔ we de mɛn yu kin ɛp yu fɔ dil wit kɔmpleks filin dɛn.

Ustɛm yu fɔ go to dɔktɔ?

If dɛn de trit yu fɔ mantle cell lymphoma, yu go nid fɔ go to yu dɔktɔ ɔltɛm. Dɛn go wach yu kɔndishɔn ɛn ɛp yu fɔ kɔntrol di sayd ɛfɛkt dɛm we yu tritmɛnt gɛt. If yu sik de na remission, yu go nid fɔ go to yu dɔktɔ wan wan tɛm (follow-ups). Aks yu dɔktɔ aw ɔltɛm yu fɔ gɛt dɛn apɔntinmɛnt ya. If yu gɛt mantle cell lymphoma (MCL), yu de liv wit di uncertainty fɔ wan sik wae nɔr de ɛva rili go. Bɔrku tɛm yu kin wɔri bɔt if de sik go kam bak. Ɔ yu go de wɔnda if di tritmɛnt fayn fɔ yu. I nɔmal fɔ fil dɛn filin ya. Bɔt if dis wɔri de mek yu nɔ ebul fɔ ɛnjɔy layf, mek shɔ se yu tɔk to yu dɔktɔ . Dɛn kin rifer yu to risɔs dɛm wae kin ɛp yu pan yu joyn.

Fɔ dɔn, mɛsej we yu kin kɛr go na os:

Mantle cell lymphoma (MCL) kin bi wɔd we de mek pɔsin fred. Bɔt i impɔtant fɔ no bɔt am, pe atɛnshɔn to di sayn dɛm, ɛn go to dɔktɔ di rayt tɛm. Mɛmba se nɔto yu wangren de. If yu gɛt di rayt tritmɛnt ɛn sɔpɔt, yu go gɛt di trɛnk fɔ bia wit dis sik. Nɔ shek fɔ sheb ɛni kwɛstyɔn ɔ tin we de mɔna yu wit yu dɔktɔ. Mantle Cell Lymphoma, Kansa, Blɔd Kansa, Limfatik Sistɛm, Simptom dɛm, Tritmɛnt